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- Qin, Fangyun, et al. Show all 12 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.24 pp. 9587-9592
- Human immunodeficiency virus 1; RNA-directed DNA polymerase; T-lymphocytes; fractionation; gene expression regulation; humans; proteins; reverse transcription; small interfering RNA
- ... Cellular proteins have been implicated as important for HIV-1 reverse transcription, but whether any are reverse transcription complex (RTC) cofactors or affect reverse transcription indirectly is unclear. Here we used protein fractionation combined with an endogenous reverse transcription assay to identify cellular proteins that stimulated late steps of reverse transcription in vitro. We identifi ...
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