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1. Improving the Detection of Hepatocellular Carcinoma using serum AFP expression in combination with GPC3 and micro-RNA miR-122 expression

Author:
Qiyu, Sun,   et al.   ; Li, Jian; Wang, Tiezheng; Jin, Boxun; Li, Ning;     Show all 5 Authors
Source:
Open life sciences 2019 v.14 no.1 pp. 53-61
ISSN:
2391-5412
Subject:
Hepatitis C virus; biomarkers; blood serum; early diagnosis; hepatoma; liver cirrhosis; microRNA; patients
Abstract:
... Early diagnosis of hepatocellular carcinoma (HCC) greatly improves the survival and prognosisfor patients. In this study weevaluate the diagnostic promise of combining serum alpha-fetoprotein (AFP) expression with two potential biomarkers, serum glypican-3 (GPC3) and expression of the micro-RNA miR-122 for hepatitis C virus (HCV) related early-stage HCC. For this study serum samples from 47 patien ...
DOI:
10.1515/biol-2019-0007