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- Rahman, Shaila, et al. Show all 5 Authors
- Nucleic acids research 2008 v.36 no.4 pp. 1237-1246
- DNA-binding domains; HIV infections; Human immunodeficiency virus 1; binding proteins; complementary DNA; ex vivo studies; nucleosomes
- ... Integration is an essential step in the retroviral lifecycle, and the lentiviral integrase binding protein lens epithelium-derived growth factor (LEDGF)/p75 plays a crucial role during human immunodeficiency virus type 1 (HIV-1) cDNA integration. In vitro, LEDGF/p75 stimulates HIV-1 integrase activity into naked target DNAs. Here, we demonstrate that this chromatin-associated protein also stimulat ...
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