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- Randle, Nadine, et al. Show all 11 Authors
- Cell and tissue research 2019 v.375 no.2 pp. 409-424
- Salmonella Typhimurium; Toxoplasma gondii; animal models; cattle; confocal microscopy; cryopreservation; epithelial cells; host-pathogen relationships; human population; humans; intestinal crypts; jejunum; morbidity; mortality; pathogens; renewable resources; rodents; slaughterhouses; staining; stem cells; swine; zoonoses
- ... The in vitro 3D culture of intestinal epithelium is a valuable resource in the study of its function. Organoid culture exploits stem cells’ ability to regenerate and produce differentiated epithelium. Intestinal organoid models from rodent or human tissue are widely available whereas large animal models are not. Livestock enteric and zoonotic diseases elicit significant morbidity and mortality in ...
- Randle, Nadine, et al. Show all 5 Authors
- Parasitology research 2017 v.116 no.10 pp. 2707-2719
- Neospora caninum; Protozoa; Toxoplasma gondii; cattle; definitive hosts; dogs; genome; gluconeogenesis; glycolysis; host range; host-parasite relationships; intermediate hosts; parasites; phosphorylation; phosphotransferases (kinases); proteins; proteome; signal transduction; transcriptome; virulence
- ... Toxoplasma gondii and Neospora caninum are closely related intracellular protozoan parasites and tissue cyst-forming Coccidia of the phylum Apicomplexa. There are remarkable similarities between the morphology, genomes and transcriptomes of both parasites. Toxoplasma is zoonotic, with a wide host range and is mainly transmitted horizontally between its definitive host, the cat, and its intermediat ...