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"Reis, Levi Eduardo Soares"
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1. Canine visceral leishmaniasis: Incidence and risk factors for infection in a cohort study in Brazil
- Author:
- Reis, Levi Eduardo Soares, et al. ; Coura-Vital, Wendel; Reis, Alexandre Barbosa; Braga, Samuel Leôncio; Roatt, Bruno Mendes; Aguiar-Soares, Rodrigo Dian de Oliveira; Marques, Marcos José; Veloso, Vanja Maria; Carneiro, Mariângela; Show all 9 Authors
- Source:
- Veterinary parasitology 2013 v.197 no.3-4 pp. 411-417
- ISSN:
- 0304-4017
- Subject:
- parasites; questionnaires; insecticides; monitoring; cohort studies; dogs; Phlebotominae; environmental management; Leishmania infantum; confidence interval; regression analysis; immunology; risk factors; seroconversion; visceral leishmaniasis; biting rates; spraying; Brazil
- Abstract:
- ... Zoonotic visceral leishmaniasis in Brazil is caused by Leishmania infantum parasites and is transmitted by sand flies of the Phlebotominae family. Dogs are the main urban reservoirs and represent the major source of contagion for the vectors. Studies have shown that most infected dogs are polymerase chain reaction-positive months before seroconversion. Herein, we describe a cohort study designed t ...
- DOI:
- 10.1016/j.vetpar.2013.07.031
- PubMed:
- 23941965
- https://dx.doi.org/10.1016/j.vetpar.2013.07.031
- Author:
- Reis, Levi Eduardo Soares, et al. ; Coura-Vital, Wendel; Roatt, Bruno Mendes; Bouillet, Leoneide Érica Maduro; Ker, Henrique Gama; Fortes de Brito, Rory Cristiane; Resende, Daniela de Melo; Carneiro, Mariângela; Giunchetti, Rodolfo Cordeiro; Marques, Marcos José; Carneiro, Cláudia Martins; Reis, Alexandre Barbosa; Show all 12 Authors
- Source:
- Veterinary parasitology 2013 v.197 no.3-4 pp. 498-503
- ISSN:
- 0304-4017
- Subject:
- DNA; DNA-directed DNA polymerase; Leishmania infantum; bone marrow; dogs; ears; enzyme-linked immunosorbent assay; fluorescent antibody technique; genes; parasites; quantitative polymerase chain reaction; spleen; visceral leishmaniasis
- Abstract:
- ... Polymerase chain reaction (PCR) and its variations represent highly sensitive and specific methods for Leishmania DNA detection and subsequent canine visceral leishmaniasis (CVL) diagnosis. The aim of this work was to compare three different molecular diagnosis techniques (conventional PCR [cPCR], seminested PCR [snPCR], and quantitative PCR [qPCR]) in samples of skin and spleen from 60 seropositi ...
- DOI:
- 10.1016/j.vetpar.2013.07.006
- PubMed:
- 23953760
- https://dx.doi.org/10.1016/j.vetpar.2013.07.006
- Author:
- Reis, Levi Eduardo Soares, et al. ; de Souza, Sheler Martins; de Abreu Vieira, Paula Melo; Roatt, Bruno Mendes; da Silva Fonseca, Kátia; Nogueira, Nívia Carolina; Reis, Alexandre Barbosa; Tafuri, Washington Luiz; Carneiro, Cláudia Martins; Show all 9 Authors
- Source:
- Molecular Immunology 2014 v.58 pp. 92-97
- ISSN:
- 0161-5890
- Subject:
- CCR5 receptor; Chagas disease; Triatominae; Trypanosoma cruzi; acute course; blood; blood transfusion; chemokines; dog diseases; dogs; gene expression; heart; host-parasite relationships; immigration; immune response; infectious diseases; inoculum; interferon-gamma; interleukin-10; interleukin-12; messenger RNA; parasitism; people; transforming growth factor beta 1; trypomastigotes; Europe; United States
- Abstract:
- ... The recent increase in immigration of people from areas endemic for Chagas disease (Trypanosoma cruzi) to the United States and Europe has raised concerns about the transmission via blood transfusion and organ transplants in these countries. Infection by these pathways occurs through blood trypomastigotes (BT), and these forms of T. cruzi are completely distinct of metacyclic trypomastigotes (MT), ...
- DOI:
- 10.1016/j.molimm.2013.11.007
- http://dx.doi.org/10.1016/j.molimm.2013.11.007
- Author:
- Reis, Levi Eduardo Soares, et al. ; Cardoso, Jamille Mirelle de Oliveira; Ker, Henrique Gama; Aguiar-Soares, Rodrigo Dian de Oliveira; Moreira, Nádia das Dores; Mathias, Fernando Augusto Siqueira; Roatt, Bruno Mendes; Vieira, Paula Melo de Abreu; Coura-Vital, Wendel; Carneiro, Cláudia Martins; Reis, Alexandre Barbosa; Show all 11 Authors
- Source:
- Veterinary parasitology 2017 v.243 pp. 260-266
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum; Phlebotominae; collagen; dog diseases; dogs; ears; histology; humans; inflammation; mast cells; necropsy; parasite load; parasites; parasitism; pathogenesis; public health; visceral leishmaniasis; zoonoses
- Abstract:
- ... Canine visceral leishmaniosis (CVL) is a zoonosis of major public health impact caused by organisms of the genus Leishmania which is transmitted to human and animals by phlebotomine sand flies. The skin is the first point of contact with Leishmania parasites for sandy fly vectors and it is considered an important reservoir compartment in infected dogs. The aim of this study was to determine the ma ...
- DOI:
- 10.1016/j.vetpar.2017.05.028
- https://dx.doi.org/10.1016/j.vetpar.2017.05.028
- Author:
- Reis, Levi Eduardo Soares, et al. ; Nunes, Juliana Barbosa; Coura-Vital, Wendel; Colombo, Fabio Antônio; Baêta, Frederico José Moreira; Pinheiro, Aimara Costa; Roatt, Bruno Mendes; Reis, Alexandre Barbosa; Marques, Marcos José; Show all 9 Authors
- Source:
- Parasitology research 2018 v.117 no.10 pp. 3341-3346
- ISSN:
- 0932-0113
- Subject:
- DNA; Leishmania infantum; blood; blood sampling; diagnostic techniques; dogs; epidemiological studies; hosts; parasites; quantitative polymerase chain reaction; spleen; tissues; veterinary clinics; visceral leishmaniasis
- Abstract:
- ... Dogs are important hosts and reservoirs of leishmaniasis, a disease caused by protozoan parasites from the genus Leishmania, affecting ~12 million people worldwide. The detection of visceral leishmaniasis (VL) in dogs by real-time PCR (qPCR) may improve on diagnosis, but the different qPCR methods available for Leishmania DNA detection have not been established as routine in diagnostic tools and/o ...
- DOI:
- 10.1007/s00436-018-6038-9
- http://dx.doi.org/10.1007/s00436-018-6038-9
- Author:
- Reis, Levi Eduardo Soares, et al. ; de Lana, Marta; Cunha, Eleonora Lima Alves; Torchelsen, Fernanda Karoline Vieira da Silva; Cunha, Lucas Maciel; Oliveira, Maykon Tavares; Fonseca, Kátia da Silva; Vieira, Paula Melo Abreu; Carneiro, Cláudia Martins; Lana, Marta; Show all 10 Authors
- Source:
- MethodsX 2019 v.6 pp. 2544-2552
- ISSN:
- 2215-0161
- Subject:
- Chagas disease; adverse effects; benznidazole; blood; dog diseases; dogs; heart; histopathology; itraconazole; parasitemia; quantitative polymerase chain reaction; serology; therapeutics; trypomastigotes; Brazil; Latin America
- Abstract:
- ... Chagas disease (CD) is a serious public health problem in Latin America and its treatment remains neglected. Benznidazole (BZ) available in Brazil, presents serious side effects and low therapeutic efficacy at chronic phase. This study evaluated the therapeutic efficacy of BZ, itraconazole (ITZ) and BZ + ITZ in dogs infected with VL-10 T. cruzi strain in the acute phase (Ethic protocol number 2013 ...
- DOI:
- 10.1016/j.mex.2019.10.007
- PubMed:
- 31908981
- PubMed Central:
- PMC6939041
- http://dx.doi.org/10.1016/j.mex.2019.10.007