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- Ren, Mingming, et al. Show all 7 Authors
- RSC advances 2019 v.9 no.9 pp. 5234-5243
- Western blotting; animal tissues; apoptosis; autophagy; cell proliferation; cisplatin; cytotoxicity; flow cytometry; gene overexpression; inhibitory concentration 50; luciferase; lung neoplasms; microRNA; multiple drug resistance; neoplasm cells; precipitin tests; protein content; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction
- ... Background: Drug resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). Recently, miRNAs are reported to be involved in the drug resistance of NSCLC. The roles of miR-124 and miR-142 in the multidrug resistance of NSCLC cells have been reported. However, the underlying mechanism by which miR-124 and miR-142 regulate resistance to cisplatin (CDDP) remains unknown. Me ...