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- Richa, Rashmi, et al. Show all 3 Authors
- Pesticide biochemistry and physiology 2019 v.153 pp. 106-115
- Mus musculus; blood serum; body weight; catalase; corticosterone; enzyme activity; gene expression; gene expression regulation; hypothalamus; males; messenger RNA; mice; neurodegenerative diseases; neuronal nitric oxide synthase; neuropeptides; paraquat; stress response; superoxide dismutase; toxicity; transcription factor NF-kappa B; translation (genetics)
- ... Paraquat (PQ) is a herbicide and well characterized pneumotoxicant which is also known to induce neurodegeneration in organisms. Aim of this study was to investigate the effect of PQ on hypothalamic – pituitary – adrenal (HPA) axis. PQ was administered i.p.10 mg/kg body weight once a week for 5 weeks in laboratory male mice. Results indicate that SOD activity decreased while catalase activity and ...