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- Author:
- Rizzo, Francesca, et al. ; Coffman, James A.; Arnone, Maria Ina; Show all 3 Authors
- Source:
- Developmental biology 2016
- ISSN:
- 0012-1606
- Subject:
- DNA; Strongylocentrotus; alanine; apoptosis; aspartic acid; cell cycle; cell proliferation; cell viability; embryogenesis; messenger RNA; mitogen-activated protein kinase; phenotype; phosphorylation; regulator genes; serine; transcription factors
- Abstract:
- ... Elk proteins are Ets family transcription factors that regulate cell proliferation, survival, and differentiation in response to ERK (extracellular-signal regulated kinase)-mediated phosphorylation. Here we report the embryonic expression and function of Sp-Elk, the single Elk gene of the sea urchin Strongylocentrotus purpuratus. Sp-Elk is zygotically expressed throughout the embryo beginning at l ...
- DOI:
- 10.1016/j.ydbio.2016.05.026
- PubMed:
- 27235147
- PubMed Central:
- PMC4961547
- http://dx.doi.org/10.1016/j.ydbio.2016.05.026
- Author:
- Rizzo, Francesca, et al. ; Panero, Riccardo; Rinaldi, Antonio; Memoli, Domenico; Nassa, Giovanni; Ravo, Maria; Tarallo, Roberta; Milanesi, Luciano; Weisz, Alessandro; Giurato, Giorgio; Show all 10 Authors
- Source:
- Bioinformatics 2017 v.33 no.6 pp. 938-940
- ISSN:
- 1460-2059
- Subject:
- algorithms; automation; bioinformatics; brain; data collection; microRNA; non-coding RNA; patients; pleiotropy; prediction; sequence analysis; user interface
- Abstract:
- ... Summary: The interest in investigating the biological roles of small non-coding RNAs (sncRNAs) is increasing, due to the pleiotropic effects of these molecules exert in many biological contexts. While several methods and tools are available to study microRNAs (miRNAs), only few focus on novel classes of sncRNAs, in particular PIWI-interacting RNAs (piRNAs). To overcome these limitations, we implem ...
- DOI:
- 10.1093/bioinformatics/btw734
- http://dx.doi.org/10.1093/bioinformatics/btw734
3. Carcinogenic risk and Bisphenol A exposure: A focus on molecular aspects in endoderm derived glands
- Author:
- Rizzo, Francesca, et al. ; Cuomo, Danila; Porreca, Immacolata; Cobellis, Gilda; Tarallo, Roberta; Nassa, Giovanni; Falco, Geppino; Nardone, Antonio; Mallardo, Massimo; Ambrosino, Concetta; Show all 10 Authors
- Source:
- Molecular and Cellular Endocrinology 2017
- ISSN:
- 0303-7207
- Subject:
- DNA repair; androgen receptors; bisphenol A; carcinogenesis; carcinogenicity; cell communication; developmental stages; epigenetics; humans; liver; neoplasms; pancreas; risk; transcriptomics
- Abstract:
- ... Epidemiological and experimental evidence associates the exposure to Bisphenol A with the increase of cancer risk in several organs, including prostate. BPA targets different pathways involved in carcinogenicity including the Nuclear Receptors (i.e. estrogen and androgen receptors), stress regulated proteins and, finally, epigenetic changes.Here, we analyse BPA-dependent carcinogenesis in endoderm ...
- DOI:
- 10.1016/j.mce.2017.01.027
- http://dx.doi.org/10.1016/j.mce.2017.01.027
- Author:
- Rizzo, Francesca, et al. ; Vitale, Nicoletta; Ballardini, Marco; Borromeo, Vitaliano; Luzzago, Camilla; Chiavacci, Laura; Mandola, Maria Lucia; Show all 7 Authors
- Source:
- Preventive veterinary medicine 2016 v.130 pp. 10-17
- ISSN:
- 0167-5877
- Subject:
- Coxiella burnetii; Q fever; animal health; antibodies; bacteria; confidence interval; cross-sectional studies; enzyme-linked immunosorbent assay; exposure duration; farm management; farms; flocks; goats; health policy; humans; immune response; immunoglobulin G; logit analysis; odds ratio; questionnaires; reproductive disorders; risk factors; seroprevalence; sheep; zoonoses; Italy
- Abstract:
- ... Q fever is a zoonosis caused by the bacterium Coxiella burnetii; domestic ruminants, mainly goats and sheep, are the main source of Q fever outbreaks in humans. From both a public and an animal health perspective, providing reliable prevalence data is extremely relevant for the decision processes by policymakers and food producer organizations.Information on Q fever seroprevalence in small ruminan ...
- DOI:
- 10.1016/j.prevetmed.2016.05.014
- https://dx.doi.org/10.1016/j.prevetmed.2016.05.014
- Author:
- Rizzo, Francesca, et al. ; Edenborough, Kathryn M.; Toffoli, Roberto; Culasso, Paola; Zoppi, Simona; Dondo, Alessandro; Robetto, Serena; Rosati, Sergio; Lander, Angelika; Kurth, Andreas; Orusa, Riccardo; Bertolotti, Luigi; Mandola, Maria Lucia; Show all 13 Authors
- Source:
- BMC veterinary research 2017 v.13 no.1 pp. 396
- ISSN:
- 1746-6148
- Subject:
- Coronavirinae; Myotis; Pipistrellus; Plecotus; RNA; Respirovirus; control methods; databases; genes; habitats; hosts; humans; mixed infection; monitoring; pathogens; phylogeny; polymerase chain reaction; public health; risk; roosting behavior; veterinary medicine; viral load; zoonoses; Italy
- Abstract:
- ... BACKGROUND: Bat-borne virus surveillance is necessary for determining inter-species transmission risks and is important due to the wide-range of bat species which may harbour potential pathogens. This study aimed to monitor coronaviruses (CoVs) and paramyxoviruses (PMVs) in bats roosting in northwest Italian regions. Our investigation was focused on CoVs and PMVs due to their proven ability to swi ...
- DOI:
- 10.1186/s12917-017-1307-x
- PubMed:
- 29273042
- PubMed Central:
- PMC5741894
- https://dx.doi.org/10.1186/s12917-017-1307-x
- Author:
- Rizzo, Francesca, et al. ; Giammarino, Mauro; Quatto, Piero; Mandola, Maria Lucia; Show all 4 Authors
- Source:
- Israel journal of ecology & evolution 2014 v.60 no.2-4 pp. 55-61
- ISSN:
- 2224-4662
- Subject:
- Anas platyrhynchos; Orthomyxoviridae; avian influenza; computer software; ecology; longevity; monitoring; variance; water birds; Italy
- Abstract:
- ... Avian influenza is an infectious viral disease of birds caused by type A strains of the influenza virus. Aquatic bird species have adapted to carry and transmit a wide range of influenza strains in nature. Here we report the results of a 4.5-year monitoring program for Orthomyxovirus prevalence in a population of wild mallard (Anas plathyrynchos) in northwestern Italy. To determine whether Orthomy ...
- DOI:
- 10.1080/15659801.2014.950478
- http://dx.doi.org/10.1080/15659801.2014.950478
- Author:
- Rizzo, Francesca, et al. ; Romano, Francesco Paolo; Caliri, Claudia; Cosentino, Luigi; Gammino, Santo; Mascali, David; Pappalardo, Lighea; Scharf, Oliver; Santos, Hellen Cristine; Show all 9 Authors
- Source:
- Analytical chemistry 2016 v.88 no.20 pp. 9873-9880
- ISSN:
- 1520-6882
- Subject:
- X-radiation; algorithms; cameras; computer software; energy; fluorescence; image analysis; least squares; photons; user interface
- Abstract:
- ... A full field-X-ray camera (FF-XRC) was developed for performing the simultaneous mapping of chemical elements with a high lateral resolution. The device is based on a conventional CCD detector coupled to a straight shaped polycapillary. Samples are illuminated at once with a broad primary beam that can consist of X-rays or charged particles in two different analytical setups. The characteristic ph ...
- DOI:
- 10.1021/acs.analchem.6b02811
- http://dx.doi.org/10.1021%2Facs.analchem.6b02811
- Author:
- Rizzo, Francesca, et al. ; Tarallo, Roberta; Giurato, Giorgio; Bruno, Giuseppina; Ravo, Maria; Salvati, Annamaria; Ricciardi, Luca; Marchese, Giovanna; Cordella, Angela; Rocco, Teresa; Gigantino, Valerio; Pierri, Biancamaria; Cimmino, Giovanni; Milanesi, Luciano; Ambrosino, Concetta; Nyman, Tuula A.; Nassa, Giovanni; Weisz, Alessandro; Show all 18 Authors
- Source:
- Genome biology 2017 v.18 no.1 pp. 189
- ISSN:
- 1474-760X
- Subject:
- RNA splicing; RNA-binding proteins; binding sites; breast neoplasms; carcinogenesis; chromatin; cytoplasm; estrogen receptors; genes; humans; mass spectrometry; messenger RNA; microRNA; prognosis; proteomics; sequence analysis; transcription (genetics)
- Abstract:
- ... BACKGROUND: The RNA-binding protein Argonaute 2 (AGO2) is a key effector of RNA-silencing pathways It exerts a pivotal role in microRNA maturation and activity and can modulate chromatin remodeling, transcriptional gene regulation and RNA splicing. Estrogen receptor beta (ERβ) is endowed with oncosuppressive activities, antagonizing hormone-induced carcinogenesis and inhibiting growth and oncogeni ...
- DOI:
- 10.1186/s13059-017-1321-0
- PubMed:
- 29017520
- PubMed Central:
- PMC5634881
- https://dx.doi.org/10.1186/s13059-017-1321-0
- Author:
- Rizzo, Francesca, et al. ; Gentilcore, Daniela; Porreca, Immacolata; Ganbaatar, Erdentuya; Carchia, Emanuele; Mallardo, Massimo; De Felice, Mario; Ambrosino, Concetta; Show all 8 Authors
- Source:
- Toxicology 2013 v.304 pp. 21-31
- ISSN:
- 0300-483X
- Subject:
- Danio rerio; bisphenol A; endocrine-disrupting chemicals; epoxides; gene expression; genes; humans; infants; models; physiological regulation; plastics; pollutants; thyroid hormones; toxicology; transcription factors
- Abstract:
- ... Bisphenol A (BPA) is an endocrine-disrupting chemical that leads to low-dose human exposure due to its ability to leach from chemically derived products, as polycarbonate plastics and epoxy resin. In addition to its known xeno-endocrine action, BPA exerts a wide range of metabolic effects. Despite the documented BPA exposure outcomes on synthesis of thyroid hormones, there are not any data availab ...
- DOI:
- 10.1016/j.tox.2012.12.001
- http://dx.doi.org/10.1016/j.tox.2012.12.001
- Author:
- Rizzo, Francesca, et al. ; Cerutti, Francesco; Ballardini, Marco; Mosca, Andrea; Vitale, Nicoletta; Radaelli, Maria Cristina; Desiato, Rosanna; Prearo, Marino; Pautasso, Alessandra; Casalone, Cristina; Acutis, Pierluigi; Peletto, Simone; Mandola, Maria Lucia; Show all 13 Authors
- Source:
- Parasites & vectors 2014 v.7 no.1 pp. 395
- ISSN:
- 1756-3305
- Subject:
- Aedes albopictus; Aedes vexans; Culex pipiens; DNA; Ochlerotatus caspius; RNA; Usutu virus; genes; humans; monitoring; mosquito control; pathogens; phylogeny; piedmont; polymerase chain reaction; risk; surveys; viruses; Czech Republic; Italy
- Abstract:
- ... BACKGROUND: The genus Flavivirus comprises several mosquito-borne species, including the zoonotic pathogens West Nile and Usutu virus, circulating in animals and humans in Italy since 1998. Due to its ecological and geographical features, Piedmont is considered a risk area for flavivirus transmission. Here we report the results of a flavivirus survey (detection and genetic characterization) of mos ...
- DOI:
- 10.1186/1756-3305-7-395
- PubMed:
- 25160565
- PubMed Central:
- PMC4150984
- http://dx.doi.org/10.1186/1756-3305-7-395
- Author:
- Rizzo, Francesca, et al. ; Romano, Francesco Paolo; Caliri, Claudia; Cosentino, Luigi; Gammino, Santo; Giuntini, Lorenzo; Mascali, David; Neri, Lorenzo; Pappalardo, Lighea; Taccetti, Francesco; Show all 10 Authors
- Source:
- Analytical chemistry 2014 v.86 no.21 pp. 10892-10899
- ISSN:
- 1520-6882
- Subject:
- X-radiation; algorithms; cameras; energy; energy-dispersive X-ray analysis; fluorescence; geometry; irradiation; photons
- Abstract:
- ... This work describes a tabletop (50 cm × 25 cm × 25 cm) full field X-ray pinhole camera (FF-XPC) presenting high energy- and high spatial-resolution. The FF-XPC consists of a conventional charge-coupled device (CCD) detector coupled, in a coaxial geometry, to a pinhole collimator of small diameter. The X-ray fluorescence (XRF) is induced on the samples with an external low-power X-ray tube. The use ...
- DOI:
- 10.1021/ac503263h
- http://dx.doi.org/10.1021%2Fac503263h
- Author:
- Rizzo, Francesca, et al. ; Tappin, Simon W; Tasker, Séverine; Show all 3 Authors
- Source:
- Journal of feline medicine and surgery 2007 v.9 no.4 pp. 319-325
- ISSN:
- 1098-612X
- Subject:
- cats; hematologic diseases; blood platelet count
- Abstract:
- ... Feline haematology profiles of patients presented to the University of Bristol Small Animal Hospital from January 2000 to October 2005 were evaluated for thrombocytosis (defined as a platelets count of >700×10⁹/l and confirmed on smear evaluation). Thrombocytosis was found in 79 cats (4.64% of the hospital feline population), with values ranging from 703 to 1895×10⁹/l. Signalment, clinical present ...
- DOI:
- 10.1016/j.jfms.2007.01.008
- PubMed:
- 17387028
- https://dx.doi.org/10.1016/j.jfms.2007.01.008
- Author:
- Rizzo, Francesca, et al. ; Sidoti, Francesca; Costa, Cristina; Astegiano, Sara; Curtoni, Antonio; Mandola, Maria Lucia; Cavallo, Rossana; Bergallo, Massimiliano; Show all 8 Authors
- Source:
- Molecular biotechnology 2010 v.44 no.1 pp. 41
- ISSN:
- 1073-6085
- Subject:
- Influenza A virus; birds; disease control; hemagglutinins; humans; poultry; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; screening; viruses
- Abstract:
- ... Rapid detection and subtyping of H5 and H7 subtypes influenza A viruses are important for disease control in poultry and potential transmission to humans. Currently, virus isolation and subsequent HA and NA subtyping constitute the standard for avian influenza viruses detection and subtype identification. These methods are highly accurate and sensitive but are also laborious and time-consuming. Re ...
- DOI:
- 10.1007/s12033-009-9211-7
- http://dx.doi.org/10.1007/s12033-009-9211-7
- Author:
- Rizzo, Francesca, et al. ; Harvey, Andrea M; Holt, Peter E; Barr, Frances J; Tasker, Séverine; Show all 5 Authors
- Source:
- Journal of feline medicine and surgery 2007 v.9 no.5 pp. 424-431
- ISSN:
- 1098-612X
- Subject:
- cats; gall bladder diseases; cholelithiasis; pyruvate kinase; hemolytic anemia; case studies
- Abstract:
- ... A 2-year-old female neutered Somali cat was presented with vomiting and acute onset jaundice 1 year after diagnosis of pyruvate kinase (PK) deficiency. Diagnostic investigations revealed a moderate regenerative haemolytic anaemia, severe hyperbilirubinaemia and elevated liver enzymes. Ultrasonography revealed marked distension of the gall bladder and common bile duct (CBD), consistent with extrahe ...
- DOI:
- 10.1016/j.jfms.2007.02.003
- PubMed:
- 17475529
- https://dx.doi.org/10.1016/j.jfms.2007.02.003
- Author:
- Rizzo, Francesca, et al. ; Sodergren, Erica; Weinstock, George M.; Davidson, Eric H.; Cameron, R. Andrew; Gibbs, Richard A.; Angerer, Robert C.; Angerer, Lynne M.; Arnone, Maria Ina; Burgess, David R.; Burke, Robert D.; Coffman, James A.; Dean, Michael; Elphick, Maurice R.; Ettensohn, Charles A.; Foltz, Kathy R.; Hamdoun, Amro; Hynes, Richard O.; Klein, William H.; Marzluff, William; McClay, David R.; Morris, Robert L.; Mushegian, Arcady; Rast, Jonathan P.; Smith, L. Courtney; Thorndyke, Michael C.; Vacquier, Victor D.; Wessel, Gary M.; Wray, Greg; Zhang, Lan; Elsik, Christine G.; Ermolaeva, Olga; Hlavina, Wratko; Hofmann, Gretchen; Kitts, Paul; Landrum, Melissa J.; Mackey, Aaron J.; Maglott, Donna; Panopoulou, Georgia; Poustka, Albert J.; Pruitt, Kim; Sapojnikov, Victor; Song, Xingzhi; Souvorov, Alexandre; Solovyev, Victor; Wei, Zheng; Whittaker, Charles A.; Worley, Kim; Durbin, K. James; Shen, Yufeng; Fedrigo, Olivier; Garfield, David; Haygood, Ralph; Primus, Alexander; Satija, Rahul; Severson, Tonya; Gonzalez-Garay, Manuel L.; Jackson, Andrew R.; Milosavljevic, Aleksandar; Tong, Mark; Killian, Christopher E.; Livingston, Brian T.; Wilt, Fred H.; Adams, Nikki; Bellé, Robert; Carbonneau, Seth; Cheung, Rocky; Cormier, Patrick; Cosson, Bertrand; Croce, Jenifer; Fernandez-Guerra, Antonio; Genevière, Anne-Marie; Goel, Manisha; Kelkar, Hemant; Morales, Julia; Mulner-Lorillon, Odile; Robertson, Anthony J.; Goldstone, Jared V.; Cole, Bryan; Epel, David; Gold, Bert; Hahn, Mark E.; Howard-Ashby, Meredith; Scally, Mark; Stegeman, John J.; Allgood, Erin L.; Cool, Jonah; Judkins, Kyle M.; McCafferty, Shawn S.; Musante, Ashlan M.; Obar, Robert A.; Rawson, Amanda P.; Rossetti, Blair J.; Gibbons, Ian R.; Hoffman, Matthew P.; Leone, Andrew; Istrail, Sorin; Materna, Stefan C.; Samanta, Manoj P.; Stolc, Viktor; Tongprasit, Waraporn; Tu, Qiang; Bergeron, Karl-Frederik; Brandhorst, Bruce P.; Whittle, James; Berney, Kevin; Bottjer, David J.; Calestani, Cristina; Peterson, Kevin; Chow, Elly; Yuan, Qiu Autumn; Elhaik, Eran; Graur, Dan; Reese, Justin T.; Bosdet, Ian; Heesun, Shin; Marra, Marco A.; Schein, Jacqueline; Anderson, Michele K.; Brockton, Virginia; Buckley, Katherine M.; Cohen, Avis H.; Fugmann, Sebastian D.; Hibino, Taku; Loza-Coll, Mariano; Majeske, Audrey J.; Messier, Cynthia; Nair, Sham V.; Pancer, Zeev; Terwilliger, David P.; Agca, Cavit; Arboleda, Enrique; Chen, Nansheng; Churcher, Allison M.; Hallböök, F.; Humphrey, Glen W.; Idris, Mohammed M.; Kiyama, Takae; Liang, Shuguang; Mellott, Dan; Mu, Xiuqian; Murray, Greg; Olinski, Robert P.; Raible, Florian; Rowe, Matthew; Taylor, John S.; Tessmar-Raible, Kristin; Wang, D.; Wilson, Karen H.; Yaguchi, Shunsuke; Gaasterland, Terry; Galindo, Blanca E.; Gunaratne, Herath J.; Juliano, Celina; Kinukawa, Masashi; Moy, Gary W.; Neill, Anna T.; Nomura, Mamoru; Raisch, Michael; Reade, Anna; Roux, Michelle M.; Song, Jia L.; Su, Yi-Hsien; Townley, Ian K.; Voronina, Ekaterina; Wong, Julian L.; Amore, Gabriele; Branno, Margherita; Brown, Euan R.; Cavalieri, Vincenzo; Duboc, Véronique; Duloquin, Louise; Flytzanis, Constantin; Gache, Christian; Lapraz, François; Lepage, Thierry; Locascio, Annamaria; Martinez, Pedro; Matassi, Giorgio; Matranga, Valeria; Range, Ryan; Röttinger, Eric; Beane, Wendy; Bradham, Cynthia; Byrum, Christine; Glenn, Tom; Hussain, Sofia; Manning, François Gerard; Miranda, Esther; Thomason, Rebecca; Walton, Katherine; Wikramanayke, Athula; Wu, Shu-Yu; Xu, Ronghui; Brown, C. Titus; Chen, Lili; Gray, Rachel F.; Lee, Pei Yun; Nam, Jongmin; Oliveri, Paola; Smith, Joel; Muzny, Donna; Bell, Stephanie; Chacko, Joseph; Cree, Andrew; Curry, Stacey; Davis, Clay; Dinh, Huyen; Dugan-Rocha, Shannon; Fowler, Jerry; Gill, Rachel; Hamilton, Cerrissa; Hernandez, Judith; Hines, Sandra; Hume, Jennifer; Jackson, LaRonda; Jolivet, Angela; Kovar, Christie; Lee, Sandra; Lewis, Lora; Miner, George; Morgan, Margaret; Nazareth, Lynne V.; Okwuonu, Geoffrey; Parker, David; Pu, Ling-Ling; Thorn, Rachel; Wright, Rita; Show all 228 Authors
- Source:
- Science 2006 v.314 no.5801 pp. 941-952
- ISSN:
- 0036-8075
- Subject:
- Chordata; Strongylocentrotus purpuratus; bacterial artificial chromosomes; clones; evolution; genes; heterozygosity; models; sequence analysis; vertebrates
- Abstract:
- ... We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The geno ...
- DOI:
- 10.1126/science.1133609
- PubMed:
- 17095691
- PubMed Central:
- PMC3159423
- http://dx.doi.org/10.1126/science.1133609