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- Roy, Udita, et al. Show all 2 Author
- Current opinion in microbiology 2019 v.52 pp. 77-83
- Candida albicans; animals; bioavailability; cell walls; crystal structure; fungi; heme; heme iron; hemoglobin; pathogens; plasma membrane; virulent strains
- ... Heme is a bioavailable source of iron, for which different fungi have evolved several distinct acquisition mechanisms. In the iron-scarce animal host, in particular, microbial pathogens are able to utilize the large heme pool of hemoglobin. The opportunistic pathogenic fungus Candida albicans relies on a cascade of related extracellular soluble and cell wall-anchored hemophores to extract the heme ...