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- Rudolph, Cornelia, et al. Show all 10 Authors
- Chromosome research 2011 v.19 no.7 pp. 857-868
- chromosome translocation; chromosomes; fluorescence in situ hybridization; karyotyping; mice; transcription factors; trisomics
- ... Induced pluripotent stem (iPS) cells have greatly provoked people’s interest due to their enormous potential of clinical applications. Increasing care is taken with the genetic safety of iPS cells. However, up to now, the chromosomal integrity of murine iPS (miPS) cells has been largely unknown. We have observed recurrent trisomy and/or Robertsonian translocation (Rb) of chromosome 14 in six out o ...