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- Štukelj, Jernej, et al. Show all 5 Authors
- Analytical chemistry 2019 v.91 no.6 pp. 3997-4003
- bioavailability; gastrointestinal system; indomethacin; ionic strength; pH; permeability; solubility; surfactants
- ... Solubility is a physicochemical property highly dependent on the solid-state form of a compound. Thus, alteration of a compound’s solid-state form can be undertaken to enhance the solubility of poorly soluble drug compounds. In the Biopharmaceutics Classification System (BCS), drugs are classified on the basis of their aqueous solubility and permeability. However, aqueous solubility does not alway ...