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- Saisuk, W., et al. Show all 4 Authors
- Analytical chemistry 2019 v.91 no.5 pp. 3286-3293
- RNA; dengue; detection limit; nucleic acid hybridization; reverse transcription; temperature; viruses
- ... Biological RNA generally comprises secondary structure motifs which cause a problem for target RNA detection by isothermal amplification methods. The complexity of the secondary structures makes RNA targets inaccessible for probe hybridization, resulting in decreased sensitivity and selectivity. This is particularly important because the hybridization step of the isothermal amplification method re ...