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1. The Advances of Broad-Spectrum and Hot Anti-Coronavirus Drugs

Author:
Sen Zeng,   et al.   ; Yuwan Li; Wenhui Zhu; Zipeng Luo; Keke Wu; Xiaowen Li; Yiqi Fang; Yuwei Qin; Wenxian Chen; Zhaoyao Li; Linke Zou; Xiaodi Liu; Lin Yi; Shuangqi Fan;     Show all 14 Authors
Source:
Microorganisms 2022 v.10 no.7 pp. -
ISSN:
2076-2607
Subject:
Betacoronavirus 1; Infectious bronchitis virus; Middle East respiratory syndrome coronavirus; Murine hepatitis virus; Porcine epidemic diarrhea virus; Severe acute respiratory syndrome coronavirus 2; antiviral agents; chickens; diarrhea; drug therapy; gastroenteritis; humans; immunization; morbidity; mortality; public health; swine; vaccines; viruses
Abstract:
... Coronaviruses, mainly including severe acute respiratory syndrome virus, severe acute respiratory syndrome coronavirus 2, Middle East respiratory syndrome virus, human coronavirus OC43, chicken infectious bronchitis virus, porcine infectious gastroenteritis virus, porcine epidemic diarrhea virus, and murine hepatitis virus, can cause severe diseases in humans and livestock. The severe acute respir ...
DOI:
10.3390/microorganisms10071294

2. Adsorptive removal of uremic toxins using Zr-based MOFs for potential hemodialysis membranes

Author:
Sen Zeng,   et al.   ; Yaqi Hou; Yaming Zhou; Xi Zhou; Shefang Ye; Miao Wang; Lei Ren;     Show all 7 Authors
Source:
Journal of materials science 2022 v.57 no.4 pp. 2909-2923
ISSN:
0022-2461
Subject:
absorptivity; adsorption; biocompatibility; blood; density functional theory; hemodialysis; hippuric acid; hydrogen bonding; kidney diseases; polylactic acid; sulfates; van der Waals forces; zirconium
Abstract:
... Protein-bound uremic toxins (PBUTs) are difficult to remove through dialytic procedures, and the accumulation of PBUTs is always associated with adverse symptoms in end-stage kidney disease. Hemoperfusions and novel membranes have been developed for the removal of PBUTs, but still suffer from low efficiency. Herein, we investigated the adsorption performance of three zirconium metal–organic framew ...
DOI:
10.1007/s10853-021-06783-4

3. Antiviral activity of puerarin as potent inhibitor of influenza virus neuraminidase

Author:
Mao‐Sen Zeng,   et al.   ; Hui‐Xian Wang; Yi Ye; Jin‐Yuan Liu; Pei‐Ping Xu;     Show all 5 Authors
Source:
Phytotherapy research 2021 v.35 no.1 pp. 324-336
ISSN:
0951-418X
Subject:
Influenza A virus; Pueraria montana var. lobata; animal models; antioxidants; antiviral properties; binding capacity; cells; cholesterol; computer simulation; death; fluorescent antibody technique; infection; inflammation; liver; lungs; mechanism of action; mice; molecular dynamics; neuroprotective effect; physiological transport; phytotherapy; research; sialidase; viral load; virion
Abstract:
... Puerarin is a major isofiavone compound isolated from the root of Pueraria lobata. It was reported that puerarin had antioxidant, antiinflammatory, antitumor, cholesterol lowering, liver protective, and neuroprotective properties. However, few studies have explored the antiviral effect of puerarin and its target mechanism related to influenza virus. Here, the antiinfluenza activity of puerarin in ...
DOI:
10.1002/ptr.6803

4. Antifouling performance of in situ synthesized chitosan-zinc oxide hydrogel film against alga M. aeruginosa

Author:
Sen Zeng,   et al.   ; Xueqin Zhao; Hua Feng; Yunhua Wang; Shuo Li; Xi Zhou; Miao Wang; Lei Rei;     Show all 8 Authors
Source:
International journal of biological macromolecules 2022 v.200 pp. 234-241
ISSN:
0141-8130
Subject:
antifouling activities; cell membranes; chitosan; chlorophyll; dose response; growth retardation; hydrogels; mechanical properties; microalgae; solvents; water uptake; zinc oxide
Abstract:
... The undesirable settlement and growth of microalgae on submerged installations is a universal problem in water environment. Soft hydrogels are promising fouling-resistant materials due to the inherent surface properties. Herein, a kind of chitosan hydrogels with increasing zinc oxide (ZnO) mineral phase content were prepared by in situ sol–gel and solvent casting method, to prevent growth of algae ...
DOI:
10.1016/j.ijbiomac.2021.12.159

5. Nanoliquid Dressing with Enhancing Anti-Infection Performance under the Moderate Photothermal Effect for Wound Treatment

Author:
Sen Zeng,   et al.   ; Yaming Zhou; Hua Feng; Yanjie Jiang; Guanping Hua; Qiang Zhang; Wenlong Li; Lihuang Li; Ning Kang; Lei Ren;     Show all 10 Authors
Source:
ACS applied materials & interfaces 2021 v.13 no.16 pp. 18443-18453
ISSN:
1944-8252
Subject:
Escherichia coli; Staphylococcus aureus; biofilm; health services; inflammation; nitric acid; reactive oxygen species; sulfides; wound treatment
Abstract:
... Nonhealing wounds have become a major healthcare burden worldwide. Chronic wound healing is universally hampered by the presence of bacterial infections that form biofilms. Therefore, in this study, a novel nanoliquid dressing based on a mild photothermal heating strategy was designed to provide safe healing of biofilm-infected wounds. Dilute nitric acid (HNO₃) solution was employed to induce a re ...
DOI:
10.1021/acsami.0c21854

6. The KNRL nuclear receptor controls hydrolase‐mediated vitellin breakdown during embryogenesis in the brown planthopper, Nilaparvata lugens

Author:
Ren‐Sen Zeng,   et al.   ; Kai Lu; Yi‐Bei Cheng; Yi‐Min Li; Wen‐Ru Li; Yuan‐Yuan Song; Zhong‐Xiang Sun;     Show all 7 Authors
Source:
Insect science 2021 v.28 no.6 pp. 1633-1650
ISSN:
1672-9609
Subject:
Nilaparvata lugens; RNA interference; adults; cathepsins; egg hatchability; eggs; embryogenesis; fecundity; gene ontology; homeostasis; insects; ovipary; transcription (genetics); transcriptome; transportation; trypsin; vitellin; vitellogenesis
Abstract:
... Vitellin (Vn) homeostasis is central to the fecundity of oviparous insects. Most studies have focused on the synthesis and transportation of Vn as a building block for developing eggs during vitellogenesis; however, less is known about how the utilization of this nutrient reserve affects embryonic development. Here, we show that the single ortholog of the knirps and knirps‐like nuclear receptors, ...
DOI:
10.1111/1744-7917.12885

7. A potential antiviral activity of Esculentoside A against binding interactions of SARS-COV-2 spike protein and angiotensin converting enzyme 2 (ACE2)

Author:
Mao-Sen Zeng,   et al.   ; Wen-Di Yu; Hui-Xian Wang; Jin-Yuan Liu; Pei-Ping Xu;     Show all 5 Authors
Source:
International journal of biological macromolecules 2021 v.183 pp. 2248-2261
ISSN:
0141-8130
Subject:
Betacoronavirus 1; Phytolacca acinosa; Severe acute respiratory syndrome coronavirus 2; anti-inflammatory activity; antiviral properties; bioavailability; bioinformatics; drugs; glycoproteins; molecular dynamics; pandemic; pathogenesis; saponins; toxicity; virus replication; viruses
Abstract:
... The recent emergence of the novel coronavirus (SARS-CoV-2) has resulted in a devastating pandemic with global concern. However, to date, there are no regimens to prevent and treat SARS-CoV-2 virus. There is an urgent need to identify novel leads with anti-viral properties that impede viral pathogenesis in the host system. Esculentoside A (EsA), a saponin isolated from the root of Phytolacca escule ...
DOI:
10.1016/j.ijbiomac.2021.06.017

8. Activiation of the nitric oxide cycle by citrulline and arginine restores susceptibility of resistant brown planthoppers to the insecticide imidacloprid

Author:
Ren-sen Zeng,   et al.   ; Mohammed Esmail Abdalla Elzaki; Zhen-fang Li; Jie Wang; Lu Xu; Nannan Liu; Yuan-yuan Song;     Show all 7 Authors
Source:
Journal of hazardous materials 2020 v.396 pp. 122755
ISSN:
0304-3894
Subject:
Fulgoroidea; arginine; citrulline; cytochrome P-450; imidacloprid; insect pests; insecticide resistance; nitric oxide
Abstract:
... Pest management, which is critical for global crop productivity, is hampered by rapidly evolving insecticide resistance in insect pests. The ability to manage the development of insecticide resistance is thus vital. Nitric oxide (NO) is a ubiquitous signaling molecule with important functions in a variety of biological processes. Here we show that imidacloprid-resistant brown planthoppers (BPH) ar ...
DOI:
10.1016/j.jhazmat.2020.122755

9. Self-recognizing and stimulus-responsive carrier-free metal-coordinated nanotheranostics for magnetic resonance/photoacoustic/fluorescence imaging-guided synergistic photo-chemotherapy

Author:
Sen Zeng,   et al.   ; Li Tu; Zhongxiong Fan; Fukai Zhu; Qiang Zhang; Zhong Chen; Lei Ren; Zhenqing Hou; Shefang Ye; Yang Li;     Show all 10 Authors
Source:
Journal of materials chemistry B 2020 v.8 no.26 pp. 5667-5681
ISSN:
2050-7518
Subject:
Food and Drug Administration; acidity; biosafety; blood circulation; fluorescence; folic acid; ligands; magnetism; methotrexate; neoplasms; photochemotherapy; photosensitizing agents; precision medicine; toxicity
Abstract:
... Carrier-free nanotheranostics directly assembled by using clinically used photosensitizers and chemotherapeutic drugs are a promising alternative to tumor theranostics. However, the weak interaction-driven assembly still suffers from low structural stability against disintegration, lack of targeting specificity, and poor stimulus-responsive property. Moreover, almost all exogenous ligands possess ...
DOI:
10.1039/d0tb00850h

10. Optimization of Nanostructured Copper Sulfide to Achieve Enhanced Enzyme-Mimic Activities for Improving Anti-Infection Performance

Author:
Sen Zeng,   et al.   ; Yaming Zhou; Zhou Chen; Chufan Wang; Wenlong Li; Miao Wang; Xiumin Wang; Xi Zhou; Xueqin Zhao; Lei Ren;     Show all 10 Authors
Source:
ACS applied materials & interfaces 2021 v.13 no.45 pp. 53659-53670
ISSN:
1944-8252
Subject:
ascorbic acid; biofilm; energy; face; glutathione; hydrogen peroxide; irradiation; nanocatalysts; peroxidase; quantum mechanics; stoichiometry; sulfides; sulfur
Abstract:
... Advanced antibacterial methods are urgently needed to deal with possible infectious diseases. As promising alternatives to antibiotics, enzyme-mimic nanocatalysts face bottlenecks of low activities and indistinct catalytic mechanisms, which seriously restrict their development for anti-infection treatment. Herein, metastable copper sulfide (Cu₂₋ₓS) nanozymes with diversiform sizes and compositions ...
DOI:
10.1021/acsami.1c17985

11. Seed priming with calcium chloride enhances wheat resistance against wheat aphid Schizaphis graminum Rondani

Author:
Ren‐Sen Zeng,   et al.   ; Jun Wang; Jia Song; Xiao‐Bao Wu; Qian‐Qian Deng; Zhong‐Yan Zhu; Ming‐Jian Ren; Mao Ye;     Show all 8 Authors
Source:
Pest management science 2021 v.77 no.10 pp. 4709-4718
ISSN:
1526-498X
Subject:
1,3-beta-glucan synthase; Schizaphis graminum; Triticum aestivum; abiotic stress; biotic stress; calcium; calcium chloride; callose; pest management; phloem; plant growth; plant response; population size; wheat
Abstract:
... BACKGROUND: Calcium is an essential macronutrient for plant growth. Although it has been shown that exogenous Ca application can increase plant resistance to abiotic stress, little is known about its potential to enhance plant tolerance to biotic stress. Here, we investigated whether pretreatment of wheat (Triticum aestivum L.) seeds with calcium chloride (CaCl₂) improves plant resistance against ...
DOI:
10.1002/ps.6513

12. Plant allelochemicals affect tolerance of polyphagous lepidopteran pest Helicoverpa armigera (Hübner) against insecticides

Author:
Ren-sen Zeng,   et al.   ; Shi Chen; Mohammed Esmail Abdalla Elzaki; Chaohui Ding; Zheng-fang Li; Jie Wang; Yuan-Yuan Song;     Show all 7 Authors
Source:
Pesticide biochemistry and physiology 2019 v.154 pp. 32-38
ISSN:
0048-3575
Subject:
Helicoverpa armigera; acetylcholinesterase; allelochemicals; carboxylesterase; chlorpyrifos; coumarin; cytochrome P-450; dimboa; fat body; flavones; genes; glutathione transferase; host plants; hydroxamic acids; larvae; methomyl; midgut; mortality; pests; piperonyl butoxide; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction
Abstract:
... Cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae), is a polyphagous lepidopteran pest distributed worldwide with a broad spectrum of host plants. However, the mechanism of H. armigera adaptation to various insecticides and defensive allelochemicals in its host plants is not fully understood. Therefore, this study examined the influence of consumption of plant allelochemicals ...
DOI:
10.1016/j.pestbp.2018.12.009

13. LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway

Author:
Wei-sen Zeng,   et al.   ; Ting-ru Shao; Ze-nan Zheng; Yue-chuan Chen; Qing-qing Wu; Guang-zhao Huang; Fei Li; Xiao-zhi Lv;     Show all 8 Authors
Source:
Life sciences 2019 v.239 pp. 117087
ISSN:
0024-3205
Subject:
apoptosis; beta catenin; cell movement; cell proliferation; histology; lymph nodes; metastasis; non-coding RNA; patients; prognosis; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; squamous cell carcinoma; therapeutics; tissues
Abstract:
... Long noncoding RNA (lncRNA) AC007271.3 has been identified to be dysregulated in oral squamous cell carcinoma (OSCC) in our previous study. However, the precise role of AC007271.3 in OSCC remains unclear. In this study, we investigated the potential functions and the underlying mechanisms of AC007271.3 in OSCC.The expression levels of AC007271.3 in OSCC tissues and cell lines were examined using R ...
DOI:
10.1016/j.lfs.2019.117087

14. Bioactivation of aflatoxin B1 by a cytochrome P450, CYP6AE19 induced by plant signaling methyl jasmonate in Helicoverpa armigra (Hübner)

Author:
Ren-sen Zeng,   et al.   ; Mohammed Esmail Abdalla Elzaki; Rong-rong Xue; Lin Hu; Jin-da Wang; Yuan-yuan Song;     Show all 6 Authors
Source:
Pesticide biochemistry and physiology 2019 v.157 pp. 211-218
ISSN:
0048-3575
Subject:
Helicoverpa armigera; RNA interference; aflatoxin B1; cytochrome P-450; diet; double-stranded RNA; genes; glutathione transferase; herbivores; jasmonic acid; larvae; methyl jasmonate; models; mortality; nucleotide sequences; risk; signal transduction; toxicity
Abstract:
... Herbivore attack leads to enhanced production of defensive compounds to mount anti-herbivore defense in plants via activation of the jasmonate signaling pathway. On the other hand, some herbivores can eavesdrop on plants defense signaling and up-regulate their cytochrome P450 genes to increase detoxification of defensive compounds. However, the ecological risk of eavesdropping on plant defense sig ...
DOI:
10.1016/j.pestbp.2019.03.020

15. Identification of a novel cytochrome P450 CYP321B1 gene from tobacco cutworm (Spodoptera litura) and RNA interference to evaluate its role in commonly used insecticides

Author:
Ren‐Sen Zeng,   et al.   ; Rui‐Long Wang; Keyan Zhu‐Salzman; Scott R. Baerson; Xiao‐Wei Xin; Jun Li; Yi‐Juan Su;     Show all 7 Authors
Source:
Insect science 2017 v.24 no.2 pp. 235-247
ISSN:
1672-9609
Subject:
RNA interference; Spodoptera litura; amino acids; chlorpyrifos; complementary DNA; cytochrome P-450; fat body; genes; insects; larvae; lethal concentration 50; methomyl; midgut; monitoring; mortality; open reading frames; pests; piperonyl butoxide; pupal development; reverse transcriptase polymerase chain reaction; synergism; toxicity
Abstract:
... Insect cytochrome P450 monooxygenases (CYPs or P450s) play an important role in detoxifying insecticides leading to resistance in insect populations. A polyphagous pest, Spodoptera litura, has developed resistance to a wide range of insecticides. In the present study, a novel P450 gene, CYP321B1, was cloned from S. litura. The function of CYP321B1 was assessed using RNA interference (RNAi) and mon ...
DOI:
10.1111/1744-7917.12315

16. Characterization of highly interconnected porous poly(lactic acid) and chitosan-coated poly(lactic acid) scaffold fabricated by vacuum-assisted resin transfer molding and particle leaching

Author:
Sen Zeng,   et al.   ; Zhixiang Cui; Zhangqiang Yang; Junhui Si; Qianting Wang; Xiaofeng Wang; Kaiping Peng; Wenzhe Chen;     Show all 8 Authors
Source:
Journal of materials science 2016 v.51 no.22 pp. 9958-9970
ISSN:
0022-2461
Subject:
absorption; biocompatibility; chitosan; coatings; hydrophilicity; leaching; mechanical properties; microstructure; particle size; polylactic acid; porosity; separation; sodium chloride; solvents
Abstract:
... Polylactic acid (PLA) scaffolds were prepared using vacuum-assisted resin transfer molding (VARTM), phase separation, solvent extraction, and particle leaching approaches. A chitosan (CS)-coated PLA scaffold was then fabricated using CS coating treatment. To control the pore morphology and porosity, different processing parameters, such as NaCl particle size and PLA solution concentrations were st ...
DOI:
10.1007/s10853-016-0203-2

17. Control of Panama Disease of Banana by Rotating and Intercropping with Chinese Chive (Allium Tuberosum Rottler): Role of Plant Volatiles

Author:
Ren Sen Zeng,   et al.   ; Hui Zhang; Azim Mallik;     Show all 3 Authors
Source:
Journal of chemical ecology 2013 v.39 no.2 pp. 243-252
ISSN:
0098-0331
Subject:
Allium tuberosum; Fusarium oxysporum; Fusarium wilt; Musa; agricultural land; antifungal agents; antimicrobial properties; bananas; biodiversity; chives; intercropping; leachates; leaves; roots; spore germination; volatile compounds; China; Panama
Abstract:
... Intercropping and rotating banana (Musa spp.) with Chinese chive (Allium tuberosum Rottler) has been used as an effective method to control Panama disease (Fusarium wilt) of banana in South China. However, the underlying mechanism is unknown. In this study, we used aqueous leachates and volatiles from Chinese chive to evaluate their antimicrobial activity on Fusarium oxysporum f. sp. cubense race ...
DOI:
10.1007/s10886-013-0243-x
PubMed:
23355016

18. Ratoon rice generated from primed parent plants exhibit enhanced herbivore resistance

Author:
Ren‐Sen Zeng,   et al.   ; Mao Ye; Yuan‐Yuan Song; Scott R. Baerson; Jun Long; Jie Wang; Zhiqiang Pan; Wen‐Xiong Lin;     Show all 8 Authors
Source:
Plant, cell and environment 2017 v.40 no.5 pp. 779-787
ISSN:
0140-7791
Subject:
RNA interference; rice; labor; insect larvae; pest resistance; trypsin; hydroperoxide dehydratase; jasmonic acid; parents; ratooning; peroxidase; crop production; catechol oxidase; plant-insect relations; methyl jasmonate; resistance mechanisms; pathogenesis-related proteins; vegetative growth; biosynthesis; phytophagous insects; Cnaphalocrocis medinalis; proteinase inhibitors
Abstract:
... Rice ratooning is practiced in many rice‐growing countries for achieving increased rice production with limited labour input. Here, we report that attack by insect herbivores, or treatment with a defense signaling compound in parent plants, can prime anti‐herbivore defense responses in subsequent ratoon plants. We compared the defense responses of rice ratoons generated from parent plants that had ...
Handle:
10113/5801789
DOI:
10.1111/pce.12897

19. Expression Analysis of Two P450 Monooxygenase Genes of the Tobacco Cutworm Moth (Spodoptera litura) at Different Developmental Stages and in Response to Plant Allelochemicals

Author:
Ren-Sen Zeng,   et al.   ; Rui-Long Wang; Jun Li; Christian Staehelin; Xiao-Wei Xin; Yi-Juan Su;     Show all 6 Authors
Source:
Journal of chemical ecology 2015 v.41 no.1 pp. 111-119
ISSN:
0098-0331
Subject:
Spodoptera litura; adults; allelochemicals; amino acids; cinnamic acid; complementary DNA; coumarin; crops; cytochrome P-450; diet; food safety; genes; hemolymph; insect control; insecticides; larvae; metabolism; methoxsalen; midgut; moths; nucleotide sequences; phylogeny; plant response; quantitative polymerase chain reaction; quercetin; toxicity; transcription (genetics)
Abstract:
... Cytochrome P450 monooxygenases (P450s) of insects are known to be involved in the metabolism or detoxification of plant allelochemicals and insecticides. Spodoptera litura (Lepidoptera, Noctuidae) is a polyphagous moth responsible for severe yield losses in many crops. In this study, two full-length P450 genes, CYP6B48 and CYP6B58, were cloned from S. litura. The cDNA sequences encode proteins wit ...
DOI:
10.1007/s10886-014-0540-z
PubMed:
25547988

20. Molecular, biochemical and bioassay based evidence of lower allelopathic potential in genetically modified rice

Author:
Ren Sen Zeng,   et al.   ; Khalid Mahmood; Muhammad Bismillah Khan; Muhammad Ijaz; Shi Ming Luo;     Show all 5 Authors
Source:
Plant growth regulation 2014 v.74 no.1 pp. 73-82
ISSN:
0167-6903
Subject:
Bacillus thuringiensis; Echinochloa crus-galli; Spodoptera litura; bioassays; biosynthesis; cultivars; enzyme activity; genes; genotype; herbivores; insects; isogenic lines; leachates; leaves; lettuce; mechanical damage; phenolic compounds; rhizosphere; rice; shoots; soil
Abstract:
... This study examines allelopathic potential of genetically modified rice. The experiment was conducted on two isogenic lines Bacillus thuringiensis (Bt) and non-Bacillus thuringiensis (non-Bt). Both isogenic lines have same allelopathic ability before insect feeding and after limited insect feeding (Spodoptera litura) non-Bt rice genotype demonstrates more allelopathic potential. The S. litura cann ...
DOI:
10.1007/s10725-014-9898-8