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- Servato, João Paulo S., et al. Show all 15 Authors
- Microbial pathogenesis 2019 v.135 pp. 103618
- Trypanosoma cruzi; amastigotes; angiogenesis; bioactive properties; cell cycle; chemotaxis; epimastigotes; fibrosis; leukocytes; mice; parasite load; parasites; pathogenesis; phagocytosis
- ... P21 is a protein secreted by Trypanosoma cruzi (T. cruzi). Previous studies have shown a spectrum of biological activities performed by P21 such as induction of phagocytosis, leukocyte chemotaxis and inhibition of angiogenesis. However, the activity of P21 in T. cruzi infection remains unknown. Here, we reported the role of P21 in mice harboring late T. cruzi infection. Treatment with recombinant ...