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1. Efficacy of deltamethrin, diazinon, and ivermectin on Boophilus annulatus ticks (in vitro and in vivo study)

Author:
Shaheen, Hazem M.,   et al.   ; El-Bahy, Nasr M.; Bazh, Eman K.;     Show all 3 Authors
Source:
Parasitology research 2015 v.114 no.1 pp. 29-36
ISSN:
0932-0113
Subject:
in vivo studies; ticks; ivermectin; cattle; farms; diazinon; tick control; disease transmission; anthelmintics; Rhipicephalus annulatus; in vitro studies; deltamethrin; eggs; adults
Abstract:
... Tick infection is considered a cause of major concern as it is a vector for some disease transmission. The use of chemicals to control tick infection is increasing in farm systems. The efficacy of three chemicals was studied on the tick Boophilus annulatus. In vitro and in vivo studies were done. The active ticks were collected from naturally infected cattle for in vitro study. They were incubated ...
DOI:
10.1007/s00436-014-4129-9
PubMed:
25398684

2. The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice

Author:
Shaheen, Hazem M.,   et al.   ; Onoda, Atsuto; Shinkai, Yusuke; Nakamura, Masayuki; El-Ghoneimy, Ashraf A.; El-Sayed, Yasser S.; Takeda, Ken; Umezawa, Masakazu;     Show all 8 Authors
Source:
Ecotoxicology and environmental safety 2016 v.132 pp. 390-396
ISSN:
0147-6513
Subject:
air pollution; biomarkers; biosynthesis; body weight; breathing; ceramides; epithelial cells; fumonisin B1; gene expression; inflammation; males; messenger RNA; mice; oxidative stress
Abstract:
... Recent studies have suggested that inhalation of diesel exhaust (DE), a major source of air pollution, results in pulmonary alterations; however, the effects of DE at low concentrations are poorly understood. Therefore, this study was conducted to elucidate the pulmonary effects of low-level exposure to DE and the potential role of a ceramide de novo biosynthesis inhibitor, fumonisin B1 (FB1) to a ...
DOI:
10.1016/j.ecoenv.2016.06.025

3. Impact of diesel exhaust exposure on the liver of mice fed on omega-3 polyunsaturated fatty acids-deficient diet

Author:
Shaheen, Hazem M.,   et al.   ; Umezawa, Masakazu; Nakamura, Masayuki; El-Ghoneimy, Ashraf A.; Onoda, Atsuto; Hori, Hiroshi; Shinkai, Yusuke; El-Sayed, Yasser S.; El-Far, Ali H.; Takeda, Ken;     Show all 10 Authors
Source:
Food and chemical toxicology 2018 v.111 pp. 284-294
ISSN:
0278-6915
Subject:
air; anti-inflammatory activity; breathing; diet; droplets; fatty liver; gene expression; genes; histology; leptin; lipid metabolism; liver; mice; omega-3 fatty acids; polyunsaturated fatty acids; risk factors; toxicity; toxicology; triacylglycerols
Abstract:
... Exposure to diesel exhaust (DE) exacerbates non-alcoholic fatty liver disease, and may systemically affect lipid metabolism. Omega-3 polyunsaturated fatty acids (n-3 PUFA) have anti-inflammatory activity and suppresses hepatic triacylglycerol accumulation, but many daily diets are deficient in this nutrient. Therefore, the effect of DE exposure in mice fed n-3 PUFA–deficient diet was investigated. ...
DOI:
10.1016/j.fct.2017.11.027

4. Enhancement of Equid Distal Limb Wounds Healing by Topical Application of Silver Nanoparticles

Author:
Shaheen, Hazem M.,   et al.   ; Khafaga, Asmaa F.; Abu-Ahmed, Howaida M.; El-Khamary, Ahmed N.; Elmehasseb, Ibrahim M.;     Show all 5 Authors
Source:
Journal of equine veterinary science 2018 v.61 pp. 76-87
ISSN:
0737-0806
Subject:
amoxicillin; angiogenesis; antimicrobial properties; asses; cell nucleolus; fibroblasts; granulation tissue; histopathology; horses; immunohistochemistry; macrophages; metronidazole; nanosilver; nuclear membrane; silver; sulfadiazine; tissue repair; topical application; transforming growth factor beta 1; ultrastructure
Abstract:
... Healing of equine distal limb wound represents a challenging problem and occupies a vital place in everyday pathology. Silver nanoparticles (AgNPs) are attractive materials for many researchers because of their anti-inflammatory, antibacterial, and wound-healing properties; as such, this study was performed to investigate the healing efficacy of AgNPs on second-intention wound healing in five clin ...
DOI:
10.1016/j.jevs.2017.11.013

5. Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats

Author:
Shaheen, Hazem M.,   et al.   ; Abdel-Daim, Mohamed M.; Abushouk, Abdelrahman Ibrahim; Toraih, Eman A.; Fawzy, Manal S.; Alansari, Wafa S.; Aleya, Lotfi; Bungau, Simona;     Show all 8 Authors
Source:
Environmental science and pollution research international 2018 v.25 no.24 pp. 23909-23916
ISSN:
0944-1344
Subject:
alanine; albumins; alkaline phosphatase; antioxidant activity; antioxidants; aspartic acid; blood serum; brain; catalase; cholesterol; creatinine; diallyl sulfides; fipronil; gamma-glutamyltransferase; glutathione; glutathione peroxidase; insecticides; laboratory animals; lactate dehydrogenase; males; malondialdehyde; nitric oxide; oxidative stress; rats; superoxide dismutase; tissues; toxicity; triacylglycerols; urea; uric acid
Abstract:
... Fipronil (FPN) is a phenylpyrazole insecticide, widely used for agricultural and veterinary activities. Early reports indicated that FIP organ toxicity is primarily mediated by the induction of oxidative stress. Both thymoquinone (TQ) and diallyl sulfide (DAS) are natural antioxidants with established health benefits. This study investigated the potential ameliorative effects of DAS and TQ against ...
DOI:
10.1007/s11356-018-2386-3

6. Inhibitory effects of Syzygium aromaticum and Camellia sinensis methanolic extracts on the growth of Babesia and Theileria parasites

Author:
Shaheen, Hazem Mohammed,   et al.   ; Batiha, Gaber El-Saber; Beshbishy, Amany Magdy; Tayebwa, Dickson Stuart; Yokoyama, Naoaki; Igarashi, Ikuo;     Show all 6 Authors
Source:
Ticks and tick-borne diseases 2019 v.10 no.5 pp. 949-958
ISSN:
1877-959X
Subject:
Camellia sinensis; in vivo studies; ticks; Babesia caballi; cell lines; median effective concentration; oral administration; drug resistance; inhibitory concentration 50; Babesia bigemina; Theileria equi; medicinal properties; Babesia bovis; babesiosis; humans; cattle; mice; Syzygium aromaticum; kidneys; toxicity; Babesia microti; Babesia divergens; viability; green tea; fibroblasts
Abstract:
... Currently, chemotherapeutics against piroplasmosis are also associated with toxicity and the emergence of drug-resistant parasites. Therefore, the discovery of new drug compounds is necessary for the effective control of bovine and equine piroplasms. Syzygium aromaticum (clove) and Camellia sinensis (green tea) have several documented medicinal properties. In the present study, the growth-inhibiti ...
DOI:
10.1016/j.ttbdis.2019.04.016

7. Putative impacts of phytogenic additives to ameliorate lead toxicity in animal feed

Author:
Shaheen, Hazem,   et al.   ; Abd El-Hack, Mohamed E.; Abdelnour, Sameh A.; Abd El-Moneim, Abd El-Moneim E.; Arif, Muhammad; Khafaga, Asmaa; Samak, Dalia; Swelum, Ayman A.;     Show all 8 Authors
Source:
Environmental science and pollution research international 2019 v.26 no.23 pp. 23209-23218
ISSN:
0944-1344
Subject:
additives; animal models; animals; anthropogenic activities; antioxidants; chronic exposure; epithelium; feeds; health status; heavy metals; hepatocytes; hypertrophy; lead; liver; necrosis; oxidative stress; poisoning; pollutants; renal tubules; risk; spermatocytes; testes; toxicity; working conditions
Abstract:
... Lead (Pb) is a toxic heavy metal and an environmental pollutant, particularly because of its anthropogenic activity. The main impacts of Pb is recognized to cause injurious influences of various levels of the tropic chain, due to bio-accumulated lead causes many health issues such as intoxication of different body organs, such as kidneys and liver, and reproductive and nervous systems. Industrial ...
DOI:
10.1007/s11356-019-05805-8