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- Shaikh, Hanif, et al. Show all 48 Authors
- Vaccine 2017 v.35 no.45 pp. 6228-6237
- Rotavirus; children; clinical trials; diarrhea; gastroenteritis; infants; monitoring; morbidity; mortality; oral administration; vaccination; vaccines; India
- ... Rotavirus is the most common cause of moderate-to-severe infant diarrhoea in developing countries, resulting in enormous morbidity, mortality, and economic burden. A bovine-human reassortant pentavalent rotavirus vaccine (BRV-PV) targeting the globally most common strains was developed in India and tested in a randomized, double-blind, placebo-controlled end-point driven Phase III efficacy clinica ...
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- Shaikh, Hanif, et al. Show all 28 Authors
- Vaccine 2014 v.32 pp. A110
- Rotavirus; children; clinical trials; diarrhea; gastroenteritis; infants; monitoring; vaccines; India
- ... Rotavirus gastroenteritis is one of the leading causes of diarrhea in Indian children less than 2 years of age. The 116E rotavirus strain was developed as part of the Indo-US Vaccine Action Program and has undergone efficacy trials. This paper reports the efficacy and additional safety data in children up to 2 years of age.In a double-blind placebo controlled multicenter trial, 6799 infants aged 6 ...