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- Shimizu, Kumiko, et al. Show all 9 Authors
- Journal of bioscience and bioengineering 2017 v.123 no.4 pp. 437-443
- Escherichia coli; NAD (coenzyme); NADH dehydrogenase; acetic acid; biochemical pathways; fermentation; gene deletion; glucose; microbial physiology; mutants; pyruvate dehydrogenase (lipoamide); pyruvic acid; transcription factors
- ... Pyruvate dehydrogenase complex regulator (PdhR) is a transcriptional regulator that negatively regulates formation of pyruvate dehydrogenase complex (PDHc), NADH dehydrogenase (NDH)-2, and cytochrome bo3 oxidase in Escherichia coli. To investigate the effects of a PdhR defect on glucose metabolism, a pdhR deletion mutant was derived from the wild-type E. coli W1485 strain by λ Red-mediated recombi ...