Jump to Main Content
- Shimizu, Maria Heloisa Massola, et al. Show all 4 Authors
- Life sciences 2019 v.231 pp. 116544
- acetylcysteine; albuminuria; blood pressure; blood serum; creatinine; drinking water; fibrosis; heart; high sodium diet; ischemia; kidneys; laboratory animals; males; rats; renal function; sodium chloride; surgery; water treatment
- ... To investigate the effect of long-term N-acetyl-l-cysteine (NAC) treatment in Wistar rats subjected to renal ischemia and reperfusion (IR) and a chronic high‑sodium diet (HSD).Adult male Wistar rats received an HSD (8.0% NaCl) or a normal‑sodium diet (NSD; 1.3% NaCl) and NAC (600 mg/L) or normal drinking water starting at 8 weeks of age. At 11 weeks of age, the rats from both diet and NAC or water ...