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- Stapels, Daphne A. C., et al. Show all 12 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2014 v.111 no.36 pp. 13187-13192
- Staphylococcus aureus; bacteria; crystallography; immune response; neutrophils; pathogenicity; proteinase inhibitors; proteins; serine proteinases
- ... Significance Neutrophils are among the first immune cells to migrate to the site of infection and clear invading bacteria. They store large amounts of neutrophil serine proteases (NSPs) that play key roles in immune defense. Unfortunately, NSPs also contribute to tissue destruction in a variety of inflammatory disorders. In this study we discover that the pathogenic bacterium Staphylococcus aureus ...
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