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methicillin-resistant Staphylococcusaureus, etc ; peptides; surfactants; therapeutics; Show all 4 Subjects
Abstract:
... To address the challenge from microbial resistance, this work developed a surfactant with 18-carbon single hydrocarbon chain and multi-amine head groups (C18N3). After assembling with Staphylococcus aureus-targeting peptide (CARG), the obtained C18N3/CARG assemblies exhibited excellent antimicrobial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in vitro a ...
Staphylococcusaureus, etc ; absorption; irradiation; light; photocatalysis; photocatalysts; polymerization; polymers; Show all 8 Subjects
Abstract:
... The low utilization of visible light and the fast recombination of photogenerated electron–hole pairs are the two intrinsic defects that have hindered the antibacterial applications of TiO₂. The addition of organic photocatalytic agents to form heterojunctions with TiO₂ powder can effectively address these problems. A novel linear conjugated polymer poly[(thiophene–ethylene–thiophene)-thiophene-3- ...
Staphylococcusaureus, etc ; cell membranes; electron microscopy; erythrocytes; hemolysins; transmembrane proteins; Show all 6 Subjects
Abstract:
... Staphylococcus aureus expresses several hemolytic pore‐forming toxins (PFTs), which are all commonly composed of three domains: cap, rim and stem. PFTs are expressed as soluble monomers and assemble to form a transmembrane β‐barrel pore in the erythrocyte cell membrane. The stem domain undergoes dramatic conformational changes to form a pore. Staphylococcal PFTs are classified into two groups: one ...
Staphylococcusaureus, etc ; Escherichia coli; cost effectiveness; droplets; green chemistry; pollution; Show all 6 Subjects
Abstract:
... Metal–organic frameworks (MOFs) have recently been widely used in antimicrobial fields due to their adjustable composition and morphology. The inherent properties of MOFs (e.g., their shape, size, and metal element) are highly related to their antibacterial performance. The traditional beaker-based synthesis system to evaluate antibacterial properties of MOFs often leads to high reagent costs and ...
Staphylococcusaureus, etc ; Candida albicans; Escherichia coli; antibacterial properties; chitosan; molecular weight; Show all 6 Subjects
Abstract:
... We selected eight kinds of chitosan fibers to characterize and analyze their composition, surface morphology, and mechanical properties. Crucially, we investigated their antibacterial activity against Escherichia coli, Staphylococcus aureus and Candida albicans and the dependence on the molecular weight (Mw) and the degree of deacetylation (DD). On that basis, the relationship between antibacteria ...
Staphylococcusaureus, etc ; agricultural research; bacterial culture; hardness; milk; udders; New Zealand; Show all 7 Subjects
Abstract:
... The objectives of this study were to identify the prevalence, incidence and range of udder defects in non-dairy breed ewes in New Zealand and to investigate the range of bacteria present in milk samples. The udders of 5700 mixed-age ewes on 11 sheep farms in the lower North Island of New Zealand were examined and scored at weaning. The majority were examined again 4–6 weeks later. Milk samples wer ...
Staphylococcusaureus, etc ; bacterial growth; ceftriaxone; inoculum; minimum inhibitory concentration; models; pharmacodynamics; Show all 7 Subjects
Abstract:
... Ceftriaxone is a broad-spectrum cephalosporin that may be one option to treat methicillin-susceptible Staphylococcus aureus (MSSA). Although MSSA may be susceptible to ceftriaxone, the minimum inhibitory concentration (MIC) is generally two- to four-fold higher than other susceptible bacterial pathogens. This study aimed to explore the pharmacodynamics of ceftriaxone against MSSA and to determine ...
Staphylococcusaureus, etc ; Escherichia coli; Klebsiella pneumoniae; bacterial proteins; nucleic acids; polysaccharides; Show all 6 Subjects
Abstract:
... Bacterial FT-IR signals are extremely specific and highly reproducible, making FT-IR an efficient tool for bacterial typing at the subspecies level. The polysaccharide and nucleic acid FT-IR regions (1200–900 cm⁻¹) are recommended as a precise and reproducible pattern for bacterial typing. However, proteins are the major macromolecules present in bacteria, and the FT-IR spectral region of proteins ...
Staphylococcusaureus, etc ; Escherichia coli; chitosan; food safety; fumaric acid; oligosaccharides; technology; Show all 7 Subjects
Abstract:
... Inventions into chitosan oligosaccharide (COS) derivatives over recent decades have hugely broadened their application in food safety. Herein, monomethyl fumaric acid (MFA) was grafted on the OH position of COS to synthesise new COS‐O‐MFA derivatives and evaluated their in vitro antibacterial properties. The degrees of substitution (DS) of the derivatives yielded almost 15% with the range of 0.093 ...
Staphylococcusaureus, etc ; Escherichia; lighting; nanogels; nanosilver; photoirradiation; silver; ultraviolet radiation; yeasts; Show all 9 Subjects
Abstract:
... A robust method to prepare silver nanoclusters (AgNCs) inside a methacrylic acid-ethyl acrylate (MAA-EA) nanogel is proposed, where AgNCs were produced within the nanogel scaffold via UV-photoreduction. The impact of UV irradiation time on the formation of AgNCs and their application in biolabeling and antimicrobial properties were examined. The AgNCs formation is described by two stages; (1) Agₙ ...
Staphylococcusaureus, etc ; biocatalysis; cathodes; detection limit; electrochemiluminescence; electrochemistry; food chemistry; oxygen; Show all 8 Subjects
Abstract:
... An Ag@C hybrid bipolar electrode (BPE) sensing platform has been established for the temporal detection of Staphylococcus aureus (S. aureus) in food. Combining the advantages of anodic dissolution of Ag and cathodic biocatalysis of oxygen (O₂) reduction, this strategy showed an ultralow detection limit down to 10 CFU mL⁻¹. As the formation of Ag@C completely quenched the electrochemiluminescence ( ...
Staphylococcusaureus, etc ; Escherichia coli; chlorination; disinfection; filtration; freshwater; stormwater; wastewater treatment; China; Show all 9 Subjects
Abstract:
... Stormwater reuse is one of the most important ways to mitigate water resource shortage. However, urban stormwater contains many bacteria species, which threaten the reuse safety. Therefore, stormwater disinfection is highly needed. Although disinfection has been widely conducted in the drinking water and reclaimed water, it is rarely carried out for stormwater. This study collected the roof stormw ...
Staphylococcusaureus, etc ; biofilm; confocal microscopy; immune system; orthopedics; phenotype; plankton; social behavior; Show all 8 Subjects
Abstract:
... Understanding how bacteria adapt their social behavior to environmental changes is of crucial importance from both biological and clinical perspectives. Staphylococcus aureus is among the most common infecting agents in orthopedics, but its recalcitrance to the immune system and to antimicrobial treatments in the physiological microenvironment are still poorly understood. By means of optical and c ...
Staphylococcusaureus, etc ; antibacterial properties; imidazole; ligands; nanogold; oxidative stress; pH; temperature; thiols; Show all 9 Subjects
Abstract:
... Surface ligand plays a crucial role in regulating the physicochemical properties and functionalities of gold nanoclusters (AuNCs). Compared to the widely studied thiolate-stabilized AuNCs, the reports on imidazole-based ligands to protect AuNCs are still rare. Herein, we report the facile preparation of imidazole-stabilized AuNCs using 1-vinylimidazole as both a reducing and capping agent. The coo ...
Staphylococcusaureus, etc ; amino acid sequences; flavin-adenine dinucleotide; flavoproteins; molecular dynamics; mutants; Show all 6 Subjects
Abstract:
... The bifunctional flavin adenine dinucleotide synthetase (FADS) synthesizes the flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) co-factors essential for the function of flavoproteins. The Staphylococcus aureus FADS (SaFADS) produces FMN from riboflavin (RF) by ATP:riboflavin kinase (RFK) activity at its C-terminal domain. The N-terminal domain converts FMN to FAD under a reducing ...
methicillin-resistant Staphylococcusaureus, etc ; biofilm; biosafety; mortality; peroxidase; superoxide anion; therapeutics; toxicity; Show all 8 Subjects
Abstract:
... A rapid increase in methicillin-resistant Staphylococcus aureus (MRSA) induced infection has been noticed in recent years and the biofilm formed by MRSA further delays wound healing, causing a high mortality rate. Hence, a safe and effective superoxide radical (O₂•–) mediated self-synthesis strategy is developed to prepare Au-doped MoO₃–ₓ (Au/MoO₃–ₓ) plasmonic-semiconductor hybrid for the eliminat ...
Staphylococcusaureus, etc ; Pseudomonas aeruginosa; Weigela florida; bacterial infections; cytokines; macrophages; microbiology; phosphorylation; Show all 8 Subjects
Abstract:
... Inflammatory responses involve the action of inflammatory mediators that are necessary for the clearance of invading bacterial pathogens. However, excessive production of inflammatory mediators can damage tissues, thereby impairing bacterial clearance. Here, we examined the effects of Weigela florida on the expression of inflammatory cytokines induced by Pseudomonas aeruginosa or Staphylococcus au ...
Staphylococcusaureus, etc ; amino acid sequences; heme; hemoglobin; humans; iron; molecular biology; mutants; solvents; Show all 9 Subjects
Abstract:
... Pathogenic Staphylococcus aureus actively acquires iron from human hemoglobin (Hb) using the IsdH surface receptor. Heme extraction is mediated by a tri-domain unit within the receptor that contains its second (N2) and third (N3) NEAT domains joined by a helical linker domain. Extraction occurs within a dynamic complex, in which receptors engage each globin chain; the N2 domain tightly binds to Hb ...
methicillin-resistant Staphylococcusaureus, etc ; DNA; cholesterol; curcumin; drugs; hydrolysis; hydrophobicity; micelles; phospholipids; therapeutics; Show all 10 Subjects
Abstract:
... Curcumin has shown remarkable therapeutic utilization for various medical conditions. Still, its limited chemical stability and rapid hydrolysis capped its applications to a certain extent. Approaches have been made in the past to surpass these shortcomings by encapsulating the drug in surfactant-based micelles or liposomes and so far, natural surfactants have been used to do this bidding. Through ...
Elena V. Girich; Anton B. Rasin; Roman S. Popov; Ekaterina A. Yurchenko; Ekaterina A. Chingizova; Phan Thi Hoai Trinh; Ngo Thi Duy Ngoc; Mikhail V. Pivkin; Olesya I. Zhuravleva; Anton N. Yurchenko
Staphylococcusaureus, etc ; Aspergillus terreus; cinnamic acid; cytotoxicity; fungi; neoplasm cells; sortase A; tripeptides; Show all 8 Subjects
Abstract:
... Three new tripeptide derivatives asterripeptides A–C (1–3) were isolated from Vietnamese mangrove-derived fungus Aspergillus terreus LM.5.2. Structures of isolated compounds were determined by a combination of NMR and ESIMS techniques. The absolute configurations of all stereocenters were determined using the Murfey’s method. The isolated compounds 1–3 contain a rare fungi cinnamic acid residue. T ...