Jump to Main Content
- Strandh, Magnus, et al. Show all 12 Authors
- International journal of antimicrobial agents 2019 v.54 no.2 pp. 159-166
- Klebsiella pneumoniae; antibacterial properties; antibiotic resistance; antimicrobial peptides; bacteria; colistin; cross resistance; drugs; mechanism of action; multiple drug resistance
- ... Colistin is an antimicrobial peptide (AMP) used as a drug of last resort, although plasmid-mediated colistin resistance (MCR) has been reported. AA139 and SET-M33 are novel AMPs currently in development for the treatment of multidrug-resistant (MDR) Gram-negative bacterial infections. As many AMPs have a similar mode of action to colistin, potentially leading to cross-resistance, the antimicrobial ...