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- Sun, Haozhe, et al. Show all 10 Authors
- In vitro cellular & developmental biology 2013 v.49 no.9 pp. 679-688
- biosynthesis; cystathionine gamma-lyase; hydrogen sulfide; inflammation; lipopolysaccharides; macrophages; mice; mitogen-activated protein kinase
- ... Hydrogen sulfide (H₂S), formed mainly by the enzyme cystathionine γ-lyase (CSE) in macrophages, is emerging as a novel regulator in inflammation. Although elevated production of H₂S has been shown in inflammatory processes, the underlying molecular mechanism remains to be further elucidated. In this study, we compared parallel TLR4 knockout (TLR4⁻/⁻) mice with their wild-type counterparts followin ...