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- Torres Pérez, Sergio A., et al. Show all 5 Authors
- Developmental biology 2018 v.444 pp. S193
- DNA; DNA methylation; RNA; S-adenosylmethionine; bisulfites; epigenetics; folic acid; folic acid transporters; histones; human health; loci; lysine; metabolism; moieties; neural crest; phenotype; sequence analysis; tissues; vitamin B deficiency
- ... Folate deficiency has been known to contribute to neural tube and neural crest defects, but why these tissues are particularly affected, and which are the molecular mechanisms involved in those abnormalities are important human health questions that remain unanswered. Here we study the function of two of the main folate transporters, FolR1 and Rfc1, which are robustly expressed in these tissues. F ...