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- Author:
- Trudeau, Vance L., et al. ; Gutierrez-Villagomez, Juan Manuel; Vázquez-Martínez, Juan; Ramírez-Chávez, Enrique; Molina-Torres, Jorge; Show all 5 Authors
- Source:
- Journal of hazardous materials 2020 v.390 pp. 122186
- ISSN:
- 0304-3894
- Subject:
- aqueous solutions; carboxylic acids; carcinogenicity; chemical composition; gas chromatography; headspace analysis; industrial applications; mass spectrometry; mine tailings; mining; molecular weight; mutagens; naphthalene; naphthenates; oil sands; oil spills; petroleum; phenols; solid phase microextraction; water solubility; Alberta
- Abstract:
- ... Naphthenic acids (NAs) are complex mixtures of carboxylic acids from petroleum that have industrial applications and that may be released to the environment after oil spills. There is significant research on the chemical composition and toxicity of water-soluble NAs derived from oil sands mining in Alberta, Canada. Yet, little is known about low molecular weight organic compounds (LMWOC) from thes ...
- DOI:
- 10.1016/j.jhazmat.2020.122186
-
https://dx.doi.org/10.1016/j.jhazmat.2020.122186
- Author:
- Trudeau, Vance L., et al. ; Edge, Christopher B.; Baker, Leanne F.; Lanctôt, Chantal M.; Melvin, Steven D.; Gahl, Megan K.; Kurban, Marharyta; Navarro-Martín, Laia; Kidd, Karen A.; Thompson, Dean G.; Mudge, Joseph F.; Houlahan, Jeff E.; Show all 12 Authors
- Source:
- The Science of the total environment 2020 v.718 pp. 137254
- ISSN:
- 0048-9697
- Subject:
- amphibians; anthropogenic activities; benthic organisms; ecological communities; ecosystems; glyphosate; invertebrates; larvae; macrophytes; path analysis; pesticide application; regression analysis; wetlands
- Abstract:
- ... The direct effects of large-scale disturbances are readily studied because their effects are often apparent and result in large changes to ecosystems. Direct effects can cascade through the ecosystem, leading to indirect effects that are often subtle and difficult to detect. Managing anthropogenic disturbances, such as chemical contamination, requires an understanding of both direct and indirect e ...
- DOI:
- 10.1016/j.scitotenv.2020.137254
-
https://dx.doi.org/10.1016/j.scitotenv.2020.137254
- Author:
- Trudeau, Vance L., et al. ; Gutierrez-Villagomez, Juan M.; Peru, Kerry M.; Edington, Connor; Headley, John V.; Pauli, Bruce D.; Show all 6 Authors
- Source:
- Environmental science & technology 2019 v.53 no.4 pp. 2095-2104
- ISSN:
- 1520-5851
- Subject:
- Xenopus; abnormal development; amphibians; bitumen; body size; carboxylic acids; death; digestive system; edema; embryogenesis; guidelines; heart; lethal concentration 50; mass spectrometry; median effective concentration; mine tailings; mining; naphthenates; oil sands; oils; oxygen; petroleum; ponds; teratogenicity; toxic substances; wastewater
- Abstract:
- ... Naphthenic acids (NAs) are carboxylic acids naturally occurring in crude oils and bitumen and are suspected to be the primary toxic substances in wastewaters associated with oil refineries and mining of oil sands. Oil sands process-affected water (OSPW) generated by the extraction of bitumen from oil sands are a major source of NAs and are currently stored in tailings ponds. We report on the acute ...
- DOI:
- 10.1021/acs.est.8b04461
-
http://dx.doi.org/10.1021/acs.est.8b04461
- Author:
- Trudeau, Vance L., et al. ; Scaia, María Florencia; Morandini, Leonel; Noguera, CristobalAlejandro; Somoza, Gustavo Manuel; Pandolfi, Matías; Show all 6 Authors
- Source:
- Physiology & behavior 2018 v.194 pp. 481-490
- ISSN:
- 0031-9384
- Subject:
- Cichlasoma dimerus; aggression; aromatization; estrogens; females; males; physiological regulation; testosterone
- Abstract:
- ... Territorial aggression has been widely studied in males and it has been historically suggested that androgens are key mediators of this behavior. However, more recent evidence suggests that it is the aromatization to estrogens, rather than androgens themselves, that is key to regulating this behavior. Females also display aggressive behaviors, but the physiological regulation of female aggression ...
- DOI:
- 10.1016/j.physbeh.2018.06.028
-
https://dx.doi.org/10.1016/j.physbeh.2018.06.028
- Author:
- Trudeau, Vance L., et al. ; Cameron, Brooke E.; Craig, Paul M.; Show all 3 Authors
- Source:
- Environmental toxicology and chemistry 2016 v.35 no.4 pp. 788-793
- ISSN:
- 0730-7268
- Subject:
- antidepressants; aquatic organisms; carcinogenesis; ecotoxicology; endocrine-disrupting chemicals; estrogens; gonadotropins; messenger RNA; microRNA; neoplasms; physiology; plants (botany); thyroid hormones; tissues; translation (genetics); vertebrates; wildlife
- Abstract:
- ... Micro ribonucleic acids (miRNAs) are recently discovered small regulatory molecules that control messenger RNA (mRNA) translation in plants and animals and have been implicated in a variety of hormone‐related physiological pathways. Estrogens, thyroid hormones, and gonadotropins are all known to act on miRNA abundance to cause major shifts in cellular activity, physiology, and homeostatic control ...
- DOI:
- 10.1002/etc.3063
-
http://dx.doi.org/10.1002/etc.3063
- Author:
- Trudeau, Vance L., et al. ; Lefebvre, Claudine; Kimpe, Linda E.; Metcalfe, Chris D.; Blais, Jules M.; Show all 5 Authors
- Source:
- Environmental pollution 2017 v.231 pp. 1593-1600
- ISSN:
- 0269-7491
- Subject:
- Oncorhynchus mykiss; air; bioaccumulation factor; biotransformation; females; fish; models; risk; rivers; sediments; vitellogenin; wastewater; wastewater treatment; Alberta; Saskatchewan
- Abstract:
- ... The synthetic polycyclic musks HHCB (Galaxolide®) and AHTN (Tonalide®) were monitored in fathead minnows (FHMs) caged for a month at various locations in the North Saskatchewan River (NSR), upstream and downstream of the Gold Bar wastewater treatment plant that serves the city of Edmonton, AB, Canada. In addition, the distribution of these musk compounds in the river was predicted using the fugaci ...
- DOI:
- 10.1016/j.envpol.2017.09.062
-
https://dx.doi.org/10.1016/j.envpol.2017.09.062
- Author:
- Trudeau, Vance L., et al. ; Mennigen, Jan A.; Zamora, Jacob M.; Chang, John P.; Show all 4 Authors
- Source:
- Comparative biochemistry and physiology 2017 v.202 pp. 70-78
- ISSN:
- 1532-0456
- Subject:
- Carassius auratus; animal ovaries; aromatase; drugs; endocrine-disrupting chemicals; estradiol; experimental design; females; goldfish; gonadosomatic index; gonadotropin receptors; homeostasis; luteinizing hormone; males; messenger RNA; pituitary gland; reproduction; serotonin; somatotropin; testosterone; vasotocin
- Abstract:
- ... Evidence suggests that pharmaceuticals and personal care products reach urban watersheds, bioconcentrate in fish, and potentially disrupt physiological homeostasis. These impairments often affect hormone functions. Selective serotonin reuptake inhibitors (SRRIs) are increasingly studied with regards to their endocrine disrupting effects on teleost physiological processes, including reproduction. T ...
- DOI:
- 10.1016/j.cbpc.2017.08.003
-
https://dx.doi.org/10.1016/j.cbpc.2017.08.003
- Author:
- Trudeau, Vance L., et al. ; Gutierrez-Villagomez, Juan Manuel; Vázquez-Martínez, Juan; Ramírez-Chávez, Enrique; Molina-Torres, Jorge; Show all 5 Authors
- Source:
- Talanta 2017 v.162 pp. 440-452
- ISSN:
- 0039-9140
- Subject:
- additives; carboxylic acids; derivatization; distillation; emulsifiers; gas chromatography; hexane; industry; infrastructure; mass spectrometry; methanol; naphthenates; oil sands; oils; preservatives; surfactants; toxicity
- Abstract:
- ... In this study, we report for the first time the efficiency of pentafluorobenzyl bromide (PFBBr) for naphthenic acid (NA) mixtures derivatization, and the comparison in the optimal conditions to the most common NAs derivatization reagents, BF3/MeOH and N-(t-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA). Naphthenic acids are carboxylic acid mixtures of petrochemical origin. These compound ...
- DOI:
- 10.1016/j.talanta.2016.10.057
-
http://dx.doi.org/10.1016/j.talanta.2016.10.057
- Author:
- Trudeau, Vance L., et al. ; Xing, Lei; Gutierrez-Villagomez, Juan Manuel; Da Fonte, Dillon F.; Venables, Maddie J.; Show all 5 Authors
- Source:
- Aquatic toxicology 2016 v.180 pp. 78-83
- ISSN:
- 0166-445X
- Subject:
- aquatic environment; central nervous system; cytotoxicity; death; gene expression; goldfish; lactate dehydrogenase; neurogenesis; neuroglia; steroidogenesis
- Abstract:
- ... Dehydroabietic acid (DHAA) is a resin acid present in aquatic environments shown to induce cellular and molecular damage in aquatic animals. In this study, the cytotoxicity of DHAA on primary cultured goldfish radial glial cells (RGCs), an important component of the central nervous system, was evaluated. Here, it is reported that a concentration of 20mg/L DHAA affected cellular morphology and expr ...
- DOI:
- 10.1016/j.aquatox.2016.09.009
-
https://dx.doi.org/10.1016/j.aquatox.2016.09.009
- Author:
- Trudeau, Vance L., et al. ; Venables, Maddie J.; Navarro-Martín, Laia; Basak, Ajoy; Baum, Bernard R.; Zhang, Dapeng; Show all 6 Authors
- Source:
- Comparative biochemistry and physiology 2016 v.19 pp. 8-17
- ISSN:
- 1744-117X
- Subject:
- Western blotting; alternative splicing; amino acids; antibodies; brain; complementary DNA; goldfish; humans; intermediate filaments; mass spectrometry; mice; molecular weight; neurogenesis; nucleotides; protein isoforms; proteins; rapid amplification of cDNA ends; sequence analysis
- Abstract:
- ... Nestin is an intermediate filament protein involved in neurogenesis in fish, mice, and humans. In this study we used rapid amplification of cDNA ends PCR to isolate goldfish nestin (nes). PCR analysis and sequencing revealed three different nes transcripts of 4003, 2446, and 2126 nucleotides, which are predicted to generate proteins of 860, 274, and 344 amino acids in length. Sequence analysis sug ...
- DOI:
- 10.1016/j.cbd.2016.05.002
-
https://dx.doi.org/10.1016/j.cbd.2016.05.002
- Author:
- Trudeau, Vance L., et al. ; Xing, Lei; Martyniuk, Christopher J.; Esau, Crystal; Da Fonte, Dillon F.; Show all 5 Authors
- Source:
- Journal of proteomics 2016 v.144 pp. 123-132
- ISSN:
- 1874-3919
- Subject:
- Western blotting; actin; adenosine monophosphate; adenosine triphosphate; adults; agonists; biomarkers; brain; calcium; cell cycle; cyclic AMP; dopamine; dopamine receptors; estrogen receptors; females; glucose; goldfish; hormones; muscles; neurogenesis; neuroglia; neurons; neurotransmitters; phosphoglycerate dehydrogenase; protein synthesis; proteome; proteomics; quantitative polymerase chain reaction; signal transduction; stem cells; steroids; triose-phosphate isomerase
- Abstract:
- ... Radial glial cells (RGCs) are stem-like cells found in the developing and adult central nervous system. They function as both a scaffold to guide neuron migration and as progenitor cells that support neurogenesis. Our previous study revealed a close anatomical relationship between dopamine neurons and RGCs in the telencephalon of female goldfish. In this study, label-free proteomics was used to id ...
- DOI:
- 10.1016/j.jprot.2016.05.003
-
https://dx.doi.org/10.1016/j.jprot.2016.05.003
- Author:
- Trudeau, Vance L., et al. ; Salgado Costa, Carolina; Ronco, Alicia E.; Natale, Guillermo S.; Show all 4 Authors
- Source:
- Journal of Herpetology 2016 v.50 no.2 pp. 233-238
- ISSN:
- 0022-1511
- Subject:
- cannibalism; frogs; hunger; ingestion; predation; tadpoles
- Abstract:
- ... Previous studies found that two larvae of the family Ceratophryidae, Ceratophrys ornata (Ornate Horned Frogs) and Ceratophrys cranwelli (Cranwell's Horned Frogs), are able to produce underwater sounds as an antipredator strategy. Here, we determined whether tadpoles of another ceratophryid, Lepidobatrachus llanensis (Llanos Frogs), also produce underwater sounds in similar contexts of intraspecifi ...
- DOI:
- 10.1670/14-179
-
http://dx.doi.org/10.1670%2F14-179
- Author:
- Trudeau, Vance L., et al. ; Massarsky, Andrey; Labarre, Justine; Moon, Thomas W.; Show all 4 Authors
- Source:
- Aquatic toxicology 2014 v.147 pp. 68-75
- ISSN:
- 0166-445X
- Subject:
- Oncorhynchus mykiss; bioactive properties; glucocorticoid receptors; gluconeogenesis; glucose; glycogenolysis; hepatocytes; nanosilver; signal transduction; stress response; trout
- Abstract:
- ... Silver nanoparticles (AgNPs) are found in many consumer products yet their biological effects on non-target aquatic organisms are yet to be fully understood. This research aimed to investigate the effects of AgNPs on cell signaling in rainbow trout (Oncorhynchus mykiss) hepatocytes. We focused on the β-adrenoreceptor (AR), which mediates glycogenolysis, and the glucocorticoid receptor (GCR), which ...
- DOI:
- 10.1016/j.aquatox.2013.11.026
-
https://dx.doi.org/10.1016/j.aquatox.2013.11.026
- Author:
- Trudeau, Vance L., et al. ; Robinson, Stacey A.; Richardson, Sarah D.; Dalton, Rebecca L.; Maisonneuve, France; Pauli, Bruce D.; Lee‐Jenkins, Stacey S.Y.; Show all 7 Authors
- Source:
- Environmental toxicology and chemistry 2017 v.36 no.4 pp. 1101-1109
- ISSN:
- 0730-7268
- Subject:
- Lithobates sylvaticus; sublethal effects; tadpoles; metamorphosis; chronic exposure; thiamethoxam; amphibians; imidacloprid; population dynamics; aquatic ecosystems; crops
- Abstract:
- ... Neonicotinoids are prophylactically used globally on a variety of crops, and there is concern for the potential impacts of neonicotinoids on aquatic ecosystems. The intensive use of pesticides on crops has been identified as a contributor to population declines of amphibians, but currently little is known regarding the sublethal effects of chronic neonicotinoid exposure on amphibians. The objectiv ...
- DOI:
- 10.1002/etc.3739
-
http://dx.doi.org/10.1002/etc.3739
- Author:
- Trudeau, Vance L., et al. ; Della Togna, Gina; Gratwicke, Brian; Evans, Matthew; Augustine, Lauren; Chia, Han; Bronikowski, Edward J.; Murphy, James B.; Comizzoli, Pierre; Show all 9 Authors
- Source:
- Theriogenology 2017 v.91 pp. 27-35
- ISSN:
- 0093-691X
- Subject:
- Atelopus; DNA; acrosome; agonists; body weight; cryopreservation; frogs; germplasm; gonadotropin-releasing hormone; human chorionic gonadotropin; intraperitoneal injection; males; metoclopramide; mitochondria; pH; sperm concentration; urine
- Abstract:
- ... Knowledge of basic gamete biology is critical to better protect and propagate endangered amphibian species and also to develop reproductive technologies combined with germplasm cryopreservation. The objectives of the study were to test different hormonal stimulations and then characterize the quantity and quality of Panamanian golden frog (Atelopus zeteki) spermatozoa. Following intraperitoneal in ...
- DOI:
- 10.1016/j.theriogenology.2016.12.033
-
https://dx.doi.org/10.1016/j.theriogenology.2016.12.033
- Author:
- Trudeau, Vance L., et al. ; Mullally, Martha; Mimeault, Caroline; Otárola Rojas, Marco; Sanchez Vindas, Pablo; Garcia, Mario; Poveda Alvarez, Luis; Moon, Thomas W.; Gilmour, Kathleen M.; Arnason, John Thor; Show all 10 Authors
- Source:
- Aquaculture 2017 v.468 pp. 26-31
- ISSN:
- 0044-8486
- Subject:
- Oncorhynchus mykiss; aquaculture; betulinic acid; corticotropin; cortisol; cytotoxicity; diet; humans; kidneys; trout
- Abstract:
- ... The capacity of the traditional anxiolytic plant, Souroubea sympetala, and its bioactive principle, betulinic acid (BA), to lower cortisol levels in rainbow trout, Oncorhynchus mykiss, was investigated. Effects at the level of the cortisol-producing interrenal cells were investigated using an in vitro head kidney preparation. Head kidney tissue incubated with S. sympetala extract or BA produced si ...
- DOI:
- 10.1016/j.aquaculture.2016.09.040
-
https://dx.doi.org/10.1016/j.aquaculture.2016.09.040
- Author:
- Trudeau, Vance L., et al. ; Melvin, Steven D.; Show all 2 Author
- Source:
- Environmental pollution 2012 v.167 pp. 178-183
- ISSN:
- 0269-7491
- Subject:
- Lithobates; Xenopus tropicalis; amphibians; hatching; lethal concentration 50; mortality; naphthenates; oil sands; pollution; tadpoles; wildlife
- Abstract:
- ... Naphthenic acids (NA) have been identified as harmful environmental contaminants that influence survival, growth and development of wildlife. Amphibian larvae are particularly susceptible to waterborne contaminants, but little information exists regarding exposure of amphibian embryos or tadpoles to NA. Our results demonstrate that embryos of Lithobates pipiens and Silurana tropicalis exposed to 2 ...
- DOI:
- 10.1016/j.envpol.2012.04.002
- PubMed:
- 22575099
-
http://dx.doi.org/10.1016/j.envpol.2012.04.002
- Author:
- Trudeau, Vance L., et al. ; Duarte-Guterman, Paula; Show all 2 Author
- Source:
- Molecular and cellular endocrinology 2011 v.331 no.1 pp. 143-149
- ISSN:
- 0303-7207
- Subject:
- Xenopus tropicalis; amphibians; bioactive properties; estrogen receptors; gene expression; genes; masculinization; metamorphosis; reverse transcriptase polymerase chain reaction; sex hormones; tadpoles; triiodothyronine
- Abstract:
- ... In amphibians, the main role of thyroid hormones (THs) is to regulate metamorphosis; however, there is evidence that THs also affect gonadal sexual differentiation. In this study, Silurana (Xenopus) tropicalis tadpoles were exposed to triiodothyronine (T3; 0, 0.5, 5 and 50nM), the bioactive form of THs for 48h. Real-time RT-PCR analyses in the gonad–mesonephros complex (GMC) revealed that TH- and ...
- DOI:
- 10.1016/j.mce.2010.09.004
-
http://dx.doi.org/10.1016/j.mce.2010.09.004
- Author:
- Trudeau, Vance L., et al. ; Abass, Nermeen Y.; Elwakil, Houssam E.; Hemeida, Alaa A.; Abdelsalam, Nader R.; Ye, Zhi; Su, Baofeng; Alsaqufi, Ahmed S.; Weng, Chia-Chen; Dunham, Rex A.; Show all 10 Authors
- Source:
- Aquaculture 2016 v.458 pp. 140-148
- ISSN:
- 0044-8486
- Subject:
- Ictalurus furcatus; Ictalurus punctatus; actin; antifreeze proteins; aquaculture; catfish; climate change; fingerlings; freezing; genotype-environment interaction; glutamate decarboxylase; goldfish; gonadotropin-releasing hormone; heterosis; hybrids; males; natural resource management; osmoregulation; pleiotropy; risk; salinity; somatotropin; survival rate; temperature; transgenes; transgenic animals; weather
- Abstract:
- ... Organisms exposed to sub-zero temperatures are at risk of freezing damage. Fingerling channel catfish, Ictalurus punctatus, hybrid catfish (channel catfish female×blue catfish, Ictalurus furcatus, male), channel catfish transgenic for the goldfish glutamate decarboxylase 65 gene driven by the carp β-actin promoter (βA-GAD65), and channel catfish transgenic for the catfish growth hormone gene drive ...
- DOI:
- 10.1016/j.aquaculture.2016.02.031
-
https://dx.doi.org/10.1016/j.aquaculture.2016.02.031
- Author:
- Trudeau, Vance L., et al. ; Massarsky, Andrey; Strek, Laura; Craig, Paul M.; Eisa-Beygi, Shahram; Moon, Thomas W.; Show all 6 Authors
- Source:
- The Science of the total environment 2014 v.478 pp. 133-140
- ISSN:
- 0048-9697
- Subject:
- Danio rerio; adulthood; adults; antibacterial properties; aquatic environment; corticotropin; cortisol; fish; larvae; nanosilver; silver; stress response; toxicity
- Abstract:
- ... The antibacterial properties of silver nanoparticles (AgNPs) are widely exploited in a variety of medical and consumer products. AgNPs in these products can be released into the aquatic environment, however, the potential toxicity of AgNPs to organisms, including fish, is yet to be fully understood. The present study aimed to investigate the effects of the early life exposure to AgNPs on the hypot ...
- DOI:
- 10.1016/j.scitotenv.2014.01.077
-
http://dx.doi.org/10.1016/j.scitotenv.2014.01.077