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- Tuusa, Jussi T., et al. Show all 3 Authors
- FEBS journal 2010 v.277 no.13 pp. 2815-2829
- Ca2-transporting ATPase; G-protein coupled receptors; adenosine triphosphate; biogenesis; biosynthesis; calcium; calnexin; cytosol; endoplasmic reticulum; homeostasis; humans; molecular chaperones; mutants; protein folding; protein-protein interactions; quality control; reticulum
- ... Sarco(endo)plasmic reticulum calcium ATPase (SERCA)2b maintains the cellular Ca²⁺ homeostasis by transferring Ca²⁺ from the cytosol to the lumen of the endoplasmic reticulum (ER). Recently, SERCA2b has also been shown to be involved in the biosynthesis of secreted and membrane proteins via direct protein-protein interactions, involving components of the ER folding and quality-control machinery, as ...