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- Author:
- Uri Y. Levine, et al. ; Julian Trachsel; Darrell O. Bayles; Torey Looft; Heather K. Allen; Show all 5 Authors
- Source:
- Applied and environmental microbiology 2016 v.82 no.22 pp. 6788-6798
- ISSN:
- 0099-2240
- Subject:
- CoA-transferases; DNA; RNA; bacteria; bacterial communities; butyrates; colon; ecosystems; enzyme activity; genes; homeostasis; intestinal microorganisms; phylogeny; swine
- Abstract:
- ... Studying the host-associated butyrate-producing bacterial community is important because butyrate is essential for colonic homeostasis and gut health. Previous research has identified the butyryl-coA:acetate transferase (2.3.8.3) as a the main gene for butyrate production in intestinal ecosystems; however, this gene family (but) remains poorly defined. To develop analysis tools for this community, ...
- Handle:
- 10113/63276
- DOI:
- 10.1128/AEM.02307-16
- PubMed:
- 27613689
- PubMed Central:
- PMC5086572
- https://doi.org/10.1128/AEM.02307-16
- Author:
- Uri Y. Levine, et al. ; Shawn M.D. Bearson; Thad B. Stanton; Show all 3 Authors
- Source:
- Veterinary microbiology 2012 v.159 no.1-2 pp. 115-122
- ISSN:
- 0378-1135
- Subject:
- acetic acids; ribosomal RNA; Selenomonas; Salmonella Typhimurium; Anaerovibrio; Streptococcus; Escherichia; fermentation; gastrointestinal system; human health; feces; synergism; screening; Shigella; food safety; swine; Mitsuokella; probiotics; pH; nucleotide sequences
- Abstract:
- ... Salmonella continues to be a significant human health threat, and the objective of this study was to identify microorganisms with the potential to improve porcine food-safety through their antagonism of Salmonella. Anaerobic culture supernatants of 973 bacterial isolates from the gastrointestinal tract and feces of swine were screened for their capacity to inhibit the growth of Salmonella enterica ...
- DOI:
- 10.1016/j.vetmic.2012.03.027
- PubMed:
- 22503601
- https://doi.org/10.1016/j.vetmic.2012.03.027
- Author:
- Uri Y. Levine, et al. ; Heather K Allen; Torey Looft; Meggan Bandrick; Thomas A. Casey; Show all 5 Authors
- Source:
- Trends in microbiology 2013 v.21 no.3 pp. 114-119
- ISSN:
- 0966-842X
- Subject:
- animal performance; antibiotic resistance; antibiotics; disease prevention; drug therapy; feed additives; feed conversion; food animals; growth promotion; medicated feeds; prebiotics; probiotics; vaccination; vaccines
- Abstract:
- ... Alternatives to antibiotics are urgently needed in animal agriculture. The form these alternatives should take presents a complex problem due to the various uses of antibiotics in agriculture, including disease treatment, disease prevention, and growth promotion, ant the relative contribution of these uses to the antibiotic resistance problem. Numerous antibiotic alternatives, such as feed amended ...
- Handle:
- 10113/56315
- DOI:
- 10.1016/j.tim.2012.11.001
- PubMed:
- 23473629
- https://doi.org/10.1016/j.tim.2012.11.001
- Author:
- Uri Y. Levine, et al. ; Torey Looft; Heather K. Allen; Brandi L. Cantarel; Darrell O. Bayles; David P. Alt; Bernard Henrissat; Thaddeus B. Stanton; Show all 8 Authors
- Source:
- Journal of the International Society for Microbial Ecology 2014 v.8 pp. 1566-1576
- ISSN:
- 1751-7370
- Subject:
- Escherichia; Lachnobacterium; bacteria; bacterial communities; bacteriophages; cecum; cell wall components; chlortetracycline; colon; feces; feed conversion; food safety; genes; ileum; inoculum; intestinal microorganisms; metagenomics; mucosa; nucleotide sequences; penicillins; ribosomal RNA; swine
- Abstract:
- ... Disturbance of the beneficial gut microbial community is a potential collateral effect of antibiotics, which have many uses in animal agriculture (disease treatment or prevention and feed efficiency improvement). Understanding antibiotic effects on bacterial communities at different intestinal locations is essential to realize the full benefits and consequences of in-feed antibiotics. In this stud ...
- Handle:
- 10113/58451
- DOI:
- 10.1038/ismej.2014.12
- PubMed:
- 24522263
- PubMed Central:
- PMC4817603
- https://doi.org/10.1038/ismej.2014.12
- Author:
- Uri Y. Levine, et al. ; Heather K. Allen; Torey Looft; Darrell O. Bayles; Samuel Humphrey; David Alt; Thaddeus B. Stanton; Show all 7 Authors
- Source:
- mBio 2011 v.2 no.6 pp. -
- ISSN:
- 2150-7511
- Subject:
- Streptococcus; antibiotic resistance; aquatic communities; bacteria; bacterial communities; bacteriophages; carbadox; chlortetracycline; digestive system; disease prevention; drug therapy; ecosystems; feces; feed additives; feed conversion; gene transfer; genes; intestinal microorganisms; lysogeny; medicated feeds; metagenomics; models; multiple drug resistance; population; population dynamics; population structure; predator-prey relationships; predators; ribosomal RNA; risk reduction; sequence analysis; strains; swine; transporters
- Abstract:
- ... Antibiotics are a cost-effective tool for improving feed efficiency and preventing disease in agricultural animals, but the full scope of their collateral effects is not understood. Antibiotics have been shown to mediate gene transfer by inducing prophages in certain bacterial strains; therefore, one collateral effect could be prophage induction in the gut microbiome at large. Here we used metagen ...
- Handle:
- 10113/59214
- DOI:
- 10.1128/mBio.00260-11
- PubMed:
- 22128350
- PubMed Central:
- PMC3225969
- https://doi.org/10.1128/mBio.00260-11
- Author:
- Uri Y. Levine, et al. ; Shawn M.D. Bearson; Heather K. Allen; Bradley L. Bearson; Torey Looft; Brian W. Brunelle; Jalusa D. Kich; Christopher K. Tuggle; Darrell O. Bayles; David Alt; Thaddeus B. Stanton; Show all 11 Authors
- Source:
- Infection, genetics, and evolution 2013 v.16 pp. 330-340
- ISSN:
- 1567-1348
- Subject:
- Prevotella; intestinal microorganisms; ribosomal RNA; community structure; hosts; DNA; Salmonella Typhimurium; feces; Catenibacterium; salmonellosis; nucleotide sequences; bacterial communities; species diversity; colonizing ability; piglets; excretion
- Abstract:
- ... Controlling Salmonella in the food chain is complicated by the ability of Salmonella to colonize livestock without causing clinical symptoms/disease. Salmonella-carrier animals are a significant reservoir for contamination of naïve animals, the environment, and our food supply. Salmonella carriage and shedding in pigs varies greatly both experimentally and on-farm. To investigate the dynamics betw ...
- Handle:
- 10113/56318
- DOI:
- 10.1016/j.meegid.2013.03.022
- https://doi.org/10.1016/j.meegid.2013.03.022
- Author:
- Uri Y. Levine, et al. ; Kathleen K. Treseder; Teri C. Balser; Mark A. Bradford; Eoin L. Brodie; Eric A. Dubinsky; Valerie T. Eviner; Kirsten S. Hofmockel; Jay T. Lennon; Barbara J. MacGregor; Jennifer Pett-Ridge; Mark P. Waldrop; Show all 12 Authors
- Source:
- Biogeochemistry 2012 v.109 no.1-3 pp. 7-18
- ISSN:
- 0168-2563
- Subject:
- anthropogenic activities; atmospheric precipitation; biogeochemical cycles; carbon; climate; ecological function; ecosystems; eutrophication; global change; microbial activity; microbial communities; microorganisms; model validation; models; nitrogen; paper; phylogeny; temporal variation
- Abstract:
- ... Microbial communities can potentially mediate feedbacks between global change and ecosystem function, owing to their sensitivity to environmental change and their control over critical biogeochemical processes. Numerous ecosystem models have been developed to predict global change effects, but most do not consider microbial mechanisms in detail. In this idea paper, we examine the extent to which i ...
- DOI:
- 10.1007/s10533-011-9636-5
- https://doi.org/10.1007/s10533-011-9636-5