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- Vaishnav, Roopal, et al. Show all 4 Authors
- Journal of organic chemistry 2019 v.84 no.5 pp. 2512-2522
- acids; aminoquinolines; arylation; catalytic activity; chemical structure; engineering; organic chemistry; palladium; peptides; regioselectivity
- ... An approach for the synthesis of a variety of new β-aryl-β-amino acids has been developed via a palladium-catalyzed auxiliary-directed regioselective Csp³-H arylation of the unactivated β-methylene bond of β-alanine. The use of 8-aminoquinoline amide as an auxiliary efficiently directs the desired regioselective β-Csp³-H functionalization. The developed protocol enables the easy and straightforwar ...