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- Van Meer, M.M.M., et al. Show all 5 Authors
- Proceedings of the National Academy of Sciences of the United States of America 1997 v.94 no.12 pp. 6007-6012
- viral insecticides; Manduca sexta; insecticidal properties; Baculoviridae; lysosomes; mutagenesis; recombinant proteins; Lactuca sativa; carboxylic ester hydrolases; bioassays; mutants; cytochemistry; enzyme activity; infection
- ... Juvenile hormone esterase (JHE; EC 18.104.22.168), which is intrinsically involved in regulation of development of some insect larvae, is rapidly removed from the hemolymph by the pericardial cells. Lys-29 and Lys-524, which are implicated in the degradation of JHE, were mutated to Arg. Neither the half-life of the modified JHE in the hemolymph nor the catalytic parameters were changed significantly, bu ...
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