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- Wang, Bin-feng, et al. Show all 6 Authors
- European journal of plant pathology 2019 v.153 no.1 pp. 239-250
- Bursaphelenchus xylophilus; acetylcholinesterase; active sites; bromine; computer simulation; enzyme inhibition; inhibitory concentration 50; lethal concentration 50; moieties; molecular models; quaternary ammonium compounds
- ... In the present study, we have investigated nematicidal effects against Bursaphelenchus xylophilus and inhibition potential, molecular docking of 43 harmine derivatives on acetylcholinesterase in vitro and in vivo. Among them, harmine quaternary ammonium derivatives 10, 11, 12 and 13 displayed promising nematicidal effects with 48 h LC₅₀ values of 1.63, 1.63, 1.75 and 1.44 μg/mL, respectively and r ...