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Influenza A virus; Oriental traditional medicine; Trollius chinensis; Western blotting; blood; cytoplasm; epithelium; fluorescent antibody technique; lungs; nasal cavity; pharmacology; pharyngitis; pneumonia; spleen; therapeutics; viruses
Abstract:
... The flowers of Trollius chinensis Bunge (Ranunculaceae) is a traditional Chinese medicine used to treat various inflammatory diseases, including upper respiratory infections, chronic tonsillitis, and pharyngitis. Recently, there has been growing research on the antiviral role of the flowers of T. chinensis Bunge. However, little is known about its anti-influenza virus effects and the underlying me ...
... Peptidoglycan (PGN) is a unique component in the cytoderm of prokaryotes which can be recognized by different pathogen-associated molecular patterns (PAMPs) in eukaryotes, followed by a cascade of immune responses via different pathways. This review outlined the basic structure of PGN, its immunologic functions. The immunomodulation pathways mediated by PGN were elaborated. PGN induces specific im ...
... Hollow-structured hybrid nanomaterials were superior electrocatalysts on account of their unique structures and preeminent properties. This study showed the synthesis of Au decorated with hollow-structured Cu₂MoS₄ (H-CMS) nanohybrid via hydrothermal and chemical reduction methods. Furthermore, novel hydrazine (N₂H₄) electrochemical sensor was fabricated based on the as-prepared nanocomposites. The ...
... Nonlinear catastrophes caused by geological fluids are a fundamental issue in rock mechanics and the geoengineering hazard field. For the consideration of hydrodynamic force on red-bed mudstone softening damage, X-ray visualization tests on the fissure flow in mudstone block failure under hydrodynamic force was performed in this study based on block scale, and the physical phenomena of fissure see ...
... INTRODUCTION: Recent studies demonstrated that living in areas with high ambient air pollution may have adverse effects on pregnancy outcomes, but few studies have investigated its association with spontaneous abortion. Further investigation is needed to explore the acute effect and lag effect of air pollutants exposure on spontaneous abortion. OBJECTIVE: To investigate the acute effect and lag ef ...
... In this study, we aimed to clone and further investigate the novel chitosanase PoCSN75A from Penicillium oxalicum M2 that we have previously identified and characterized. Sequence alignment and bioinformatics analysis revealed the conserved regions, enzyme classification, and other properties of PoCSN75A. Furthermore, the gene encoding PoCSN75A was heterologously expressed in Pichia pastoris GS115 ...
Aspergillus niger; Saccharomyces cerevisiae; blackberries; gene expression regulation; polyphenols; proteomics; tandem mass spectrometry; wines
Abstract:
... Wine haze seriously influences customers’ purchasing decisions. Protein is an influencing factor in wine haze formation. In this study, the differentially expressed proteins (DEPs) in fresh blackberry wine (FBBW) and aged blackberry wine (ABBW) were analyzed by label-free quantitative proteomics, and the proteins in BBWH were identified by high-performance liquid chromatography-tandem mass spectro ...
... The zein-tannic acid nanoparticles (ZTNPs) were developed as antioxidants for oxidation inhibition of blackberry seed oils. These particles were spherical with an average diameter below 200 nm. The results of structural characterization indicated that tannic acid was bound to zein by electrostatic, hydrophobic, and hydrogen bonding interactions, resulting in the conformational changes of zein. The ...
... Heat stress during flowering is a critical limitation for summer maize production. However, the incidence of heat varies with years and locations, and it poses a great risk to successful maize reproduction and kernel setting. Therefore, it is essential to provide a sound quantification of heat occurrence in relation to maize growth and development. Here, we analyzed the characteristics of heat occ ...
adhesion; air; air drying; compression strength; deformation; granite; static load; water; China
Abstract:
... For Fangshan granite in Beijing, the static compression and dynamic compression tests have been carried out separately under natural air drying and water saturation. It was found that the dynamic compressive strength of water-saturated granite is higher than that of air-dried granite, which is contrary to the result that the strength of water-saturated rock is lower than that of air-dried granite ...
... This study explored the effects of varying the time of pulsed ultrasound (PUS) treatment on the physicochemical and textural properties of chicken myofibrillar protein (CMP) gel. The solubility rapidly increased at ≤ 6 min and then steadily decreased, while the particle size showed the opposite trend. At longer PUS treatment times, the total sulfhydryl(–SH)and reactive SH content of CMP gel all de ...
COVID-19 infection; Severe acute respiratory syndrome coronavirus 2; fluorescence; immune evasion; pathogens; polyproteins; proteinases; public health; virology
Abstract:
... The global scourge of COVID-19 is a serious threat to public health, but effective therapies remain very limited for this disease. Therefore, the discovery of novel antiviral agents is urgently needed to fight against COVID-19. In the lifecycle of SARS-CoV-2, the causing pathogen of COVID-19, papain-like protease (PLpro) is responsible for the cleavage of polyprotein into functional units as well ...
... As a lactic acid bacteria, Lactobacillus is an important probiotic used in aquaculture. Intestines play an important role in beneficial function of probiotic. But little is known about the mechanism of lactic acid bacteria effecting on the intestines of sea cucumber Apostichopus japonicus. Herein, the present study was designed to explore the effects of endogenous Lactobacillus rhamnosus M2–4 on t ...
... Gap junction (GJ), a special intercellular junction between different cell types, directly connects the cytoplasm of adjacent cells, allows various molecules, ions and electrical impulses to pass through the intercellular regulatory gate, and plays vital roles in response to bacterial infection. Up to date, the information about the GJ in turbot (Scophthalmus maximus L.) is still limited. In curre ...
... The endothelial glycocalyx is a carbohydrate–rich layer overlying the outermost surface of endothelial cells. It mediates intercellular interactions by specific chemical compositions (e.g., proteoglycans containing glycosaminoglycan (GAG) side chains) and micro/nanotopography. Inspired by the endothelial glycocalyx, we fabricated a series of glycocalyx–mimetic surfaces with tunable chemical compos ...
... Boscalid is a novel, highly effective carboximide fungicide that has been substantially and irrationally applied in greenhouses. However, little is known about the residual characteristics of boscalid and its ecological effects in long-term polluted greenhouse soils. Therefore, actual boscalid pollution status in greenhouse soils was simulated by repeatedly introducing boscalid into the soil under ...
... Graphene oxide (GO) nanolayer, combining extraordinary mechanical properties, separation performance and chemical stability, holds great promise for widespread applications. The current preparation of GO nanolayer is complex and requires expensive and technical equipment, which limits the further development. In this work, we deposit GO nanolayer on TiO₂ modified Polytetrafluoroethylene (PTFE) fil ...
Setaria italica; human settlements; humans; immigration; land; people; rivers; watersheds; China
Abstract:
... Human settlement numbers have significantly changed before and after ~4000 cal. y BP in the upper and middle Qin River reaches, but the external and internal factors driving this change remain unclear. In this study, we examine changing spatial and temporal patterns of the Longshan and Erlitou settlements in relation to extreme flooding at ~4000 cal. y BP and a variety of subsistence strategies du ...
Ctenopharyngodon idella; Fourier transform infrared spectroscopy; antioxidants; biodegradability; cellulose; chitosan; contact angle; oxygen; pollution; polyphenols; shelf life; tea; thermal stability; water content; water solubility; water vapor
Abstract:
... To alleviate the environmental pressure caused by plastic pollution, biodegradable films made from natural polymers are gaining popularity. In the current paper, biodegradable films were successfully prepared by incorporating tea polyphenols (TP) into chitosan-bacterial cellulose (CS-BC) matrix. The effects of different concentrations (2–10% w/w) of TP on physicochemical, antioxidant and antimicro ...
... Bacterial cellulose (BC) is a kind of high-purity cellulose biomaterial with a unique three-dimensional structure. To improve the mechanical properties and reinforce the BC composite films, in this study, we provide in detail a simple, fast, and environmentally-friendly method to prepare a biodegradable composite film using chitosan (CS) with different molecular weights and BC with excellent dispe ...