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- Xu, Keye, et al. Show all 7 Authors
- Biochemical and biophysical research communications 2019 v.508 no.1 pp. 198-202
- adipose tissue; anti-inflammatory activity; chemokine CCL2; gene transfer; genes; high fat diet; hydrodynamics; inflammation; insulin resistance; interleukin-1beta; interleukin-6; lipid content; liver; mice; obesity; plasmids; tissue weight; weight gain
- ... Obesity is associated with a chronic inflammatory response. Interleukin (IL)-38 is a poorly characterized cytokine of the IL-1 family with anti-inflammatory activity. The role of IL-38 in obesity-induced inflammation and insulin resistance remains unknown. In this study, we investigated the effects of IL-38 expression by hydrodynamic-based gene delivery on high-fat diet-induced obesity in mice. Tr ...