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- Xu, Si-Qi, et al. Show all 6 Authors
- BMC genetics 2018 v.19 no.1 pp. 109
- X chromosome; algorithms; alleles; confidence interval; females; genotype; loci; molecular genetics; population genetics; rheumatoid arthritis; statistical analysis; United States
- ... BACKGROUND: X chromosome inactivation (XCI) is an important gene regulation mechanism in females to equalize the expression levels of X chromosome between two sexes. Generally, one of two X chromosomes in females is randomly chosen to be inactivated. Nonrandom XCI (XCI skewing) is also observed in females, which has been reported to play an important role in many X-linked diseases. However, there ...