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- Xuan, Meiyan, et al. Show all 6 Authors
- Nutrients 2014 v.6 no.4 pp. 1554-1577
- animal disease models; anti-inflammatory activity; ascorbic acid; brain; caspase-3; cortex; dehydroascorbic acid; diabetes mellitus; edema; endothelial cells; glucose transporters; immunohistochemistry; infarction; interleukin-1beta; neoplasms; neurons; oxidative stress; oxidative toxicity; rats; staining; superoxide anion; tumor necrosis factor-alpha
- ... Diabetes mellitus is known to exacerbate cerebral ischemic injury. In the present study, we investigated antiapoptotic and anti-inflammatory effects of oral supplementation of ascorbic acid (AA) on cerebral injury caused by middle cerebral artery occlusion and reperfusion (MCAO/Re) in rats with streptozotocin-induced diabetes. We also evaluated the effects of AA on expression of sodium-dependent v ...