Jump to Main Content
- Yin, Xi-Jiang, et al. Show all 10 Authors
- Journal of agricultural and food chemistry 2018 v.66 no.41 pp. 10748-10759
- Moringa oleifera; anti-inflammatory activity; beta-sitosterol; caspase-1; cell lines; inflammasomes; inflammation; interleukin-1beta; interleukin-6; interleukin-8; keratinocytes; macrophages; nanoparticles; secretion; signal transduction; solubility; transcription factor NF-kappa B; tumor necrosis factor-alpha
- ... β-Sitosterol is a well known phytosterol in plants, but owing to its poor solubility in typical media, determining its cellular mechanisms has been proven to be difficult. In this study, we investigated the anti-inflammatory activity of β-sitosterol (BSS) isolated from Moringa oleifera in two cell lines. Over a dose range of 7.5 to 30 μM, BSS dispersed well in the medium as nanoparticles with diam ...