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- Yuanshu, Zhang, et al. Show all 5 Authors
- Veterinary microbiology 2010 v.144 no.3-4 pp. 409-414
- chickens; Campylobacter jejuni; bacterial infections; poultry diseases; enrofloxacin; ciprofloxacin; quinolones; antimicrobial agents; dosage; dose response; mutagenesis; mutation; mutants; transport proteins; minimum inhibitory concentration; genes
- ... The mutant prevention concentration (MPC) and mutant selection window (MSW) concepts have been used to evaluate antibiotic concentration ranges that prevent the emergence of antibiotic resistant mutants. Campylobacter jejuni is highly mutable to fluoroquinolone (FQ) antibiotics, but it is unknown if the MPC concept can be used to prevent mutant emergence. In this study, the MPCs of three FQs inclu ...