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1. Secondary Metabolites Produced by Combined Culture of Penicillium crustosum and a Xylaria sp.

Author:
Zhu, Meilin,   et al.   ; Yu, Guihong; Sun, Zichao; Peng, Jixing; Che, Qian; Zhang, Guojian; Zhu, Tianjiao; Gu, Qianqun; Li, Dehai;     Show all 9 Authors
Source:
Journal of natural products 2019 v.82 no.7 pp. 2013-2017
ISSN:
1520-6025
Subject:
Mycobacterium phlei; Penicillium crustosum; Xylaria; antibacterial properties; aromatic compounds; coculture; fungi; mass spectrometry; mixed culture; secondary metabolites; ultra-performance liquid chromatography; Antarctic region
Abstract:
... Four new alkyl aromatics, penixylarins A–D (1–4), along with the known biogenetically related 1,3-dihydroxy-5-(12-hydroxyheptadecyl)benzene (5) and 1,3-dihydroxy-5-(12-sulfoxyheptadecyl)benzene (6), were isolated from a mixed culture of the Antarctic deep-sea-derived fungus Penicillium crustosum PRB-2 and the mangrove-derived fungus Xylaria sp. HDN13-249. UPLC-MS data and an analysis of structural ...
DOI:
10.1021/acs.jnatprod.9b00345

2. Erratum to: Differences in mass balance behavior for three glaciers from different climatic regions on the Tibetan Plateau

Author:
Zhu, Meilin,   et al.   ; Yao, Tandong; Yang, Wei; Xu, Baiqing; Wu, Guanjian; Wang, Xiaojun;     Show all 6 Authors
Source:
Climate dynamics 2018 v.51 no.1-2 pp. 769
ISSN:
0930-7575
Subject:
climate; glaciers; China
Abstract:
... In the original publication of the article, Fig. 1 caption has been published incorrectly. In the original publication of the article, “OPS” in the note of Table 5 is changed to “QPS”. In the original publication of the article, “Fig. 1” in Line 15 of the second paragraph on Page 4 is changed to “Fig. S1”. In the original publication of the article, “Table S3” in Line 42 of the third paragraph on ...
DOI:
10.1007/s00382-017-3915-3

3. Differences in mass balance behavior for three glaciers from different climatic regions on the Tibetan Plateau

Author:
Zhu, Meilin,   et al.   ; Yao, Tandong; Yang, Wei; Xu, Baiqing; Wu, Guanjian; Wang, Xiaojun;     Show all 6 Authors
Source:
Climate dynamics 2018 v.50 no.9-10 pp. 3457-3484
ISSN:
0930-7575
Subject:
air temperature; climatic factors; energy; glaciers; global warming; humidity; melting; meteorological data; models; snow; China
Abstract:
... Glacier mass balance shows a spatially heterogeneous pattern in response to global warming on the Tibetan Plateau (TP), and the climate mechanisms controlling this pattern require further study. In this study, three glaciers where systematic glaciological and meteorological observations have been carried out were selected, specifically Parlung No. 4 (PL04) and Zhadang (ZD) glaciers on the southern ...
DOI:
10.1007/s00382-017-3817-4

4. A compact, low-cost, quantitative and multiplexed fluorescence detection platform for point-of-care applications

Author:
Zhu, Meilin,   et al.   ; Obahiagbon, Uwadiae; Smith, Joseph T.; Katchman, Benjamin A.; Arafa, Hany; Anderson, Karen S.; Blain Christen, Jennifer M.;     Show all 7 Authors
Source:
Biosensors & bioelectronics 2018 v.117 pp. 153-160
ISSN:
0956-5663
Subject:
Papillomaviridae; antibodies; biomarkers; biosensors; color; colorimetry; diagnostic techniques; filters; fluorescence; humans; infectious diseases; latex; microparticles; photons; point-of-care systems; probability; scanners; screening; systems engineering; uterine cervical neoplasms
Abstract:
... An effective method of combating infectious diseases is the deployment of hand-held devices at the point-of-care (POC) for screening or self-monitoring applications. There is a need for very sensitive, low-cost and quantitative diagnostic devices. In this study, we present a low-cost, multiplexed fluorescence detection platform that has a high sensitivity and wide dynamic range. Our system feature ...
DOI:
10.1016/j.bios.2018.04.002

5. Determination of arsenic speciation and the possible source of methylated arsenic in Panax Notoginseng

Author:
Zhu, Meilin,   et al.   ; Zeng, Xiancai; Jiang, Yanxue; Fan, Xiaoting; Chao, Sihong; Cao, Hongbin; Zhang, Wensheng;     Show all 7 Authors
Source:
Chemosphere 2017 v.168 pp. 1677-1683
ISSN:
0045-6535
Subject:
Panax notoginseng; arsenic; arsenites; cacodylic acid; correlation; fluorescence; genes; high performance liquid chromatography; hydrides; medicinal plants; methyltransferases; planting; reverse transcriptase polymerase chain reaction; risk; soil; toxicity; transcription (genetics)
Abstract:
... Arsenic species and a possible source of methylated arsenic in a Panax Notoginseng (PN) medicinal plant were explored to further understand the change of inorganic arsenic to the less toxic methylated form to minimize the health risks associated with its medicinal use. Arsenic speciation in PN from major planting areas was determined using high-performance liquid chromatography coupled with hydrid ...
DOI:
10.1016/j.chemosphere.2016.10.093

6. Recent accelerating mass loss of southeast Tibetan glaciers and the relationship with changes in macroscale atmospheric circulations

Author:
Zhu, Meilin,   et al.   ; Yang, Wei; Guo, Xiaofeng; Yao, Tandong; Wang, Yongjie;     Show all 5 Authors
Source:
Climate dynamics 2016 v.47 no.3-4 pp. 805-815
ISSN:
0930-7575
Subject:
air temperature; atmospheric circulation; climate change; climatic factors; cold; energy balance; glaciers; models; mountains; China
Abstract:
... The mass balance history (1980–2010) of a monsoon-dominated glacier in the southeast Tibetan Plateau is reconstructed using an energy balance model and later interpreted with regard to macroscale atmospheric variables. The results show that this glacier is characterized by significant interannual mass fluctuations over the past three decades, with a remarkably high mass loss during the recent peri ...
DOI:
10.1007/s00382-015-2872-y

7. Melt season hydrological characteristics of the Parlung No. 4 Glacier, in Gangrigabu Mountains, south‐east Tibetan Plateau

Author:
Zhu, Meilin,   et al.   ; Li, Shenghai; Yao, Tandong; Yang, Wei; Yu, Wusheng;     Show all 5 Authors
Source:
Hydrological processes 2016 v.30 no.8 pp. 1171-1191
ISSN:
0885-6087
Subject:
air temperature; autocorrelation; basins; floods; glaciers; global warming; ice; lakes; melting; models; mountains; regression analysis; snowmelt; time series analysis; vapor pressure; China
Abstract:
... With global warming, hazards relating to glacial melt, such as glacial lake outburst floods, are becoming progressively more serious. However, glacial melt processes and their hydrological consequences are very poorly understood. This study collected glacier discharge data from the terminus of the Parlung No. 4 Glacier throughout the melt season (May–October) during 2008, 2010, 2011 and 2012 to st ...
DOI:
10.1002/hyp.10696

8. Trichodermamides D–F, heterocyclic dipeptides with a highly functionalized 1,2-oxazadecaline core isolated from the endophytic fungus Penicillium janthinellum HDN13-309

Author:
Zhu, Meilin,   et al.   ; Yang, Zhen; Feng, Huimin; Gan, Qi; Che, Qian; Zhu, Tianjiao; Gu, Qianqun; Han, Bingnan; Li, Dehai;     Show all 9 Authors
Source:
RSC advances 2017 v.7 no.76 pp. 48019-48024
ISSN:
2046-2069
Subject:
Penicillium janthinellum; X-ray diffraction; dipeptides; endophytes; enzymes; fungi; heterocyclic compounds; metabolic detoxification; nuclear magnetic resonance spectroscopy
Abstract:
... Three new heterocyclic dipeptides with a highly functionalized 1,2-oxazadecaline core, named trichodermamides D–F (1–3), together with the known trichodermamides A–C (4–6), were isolated from the broth of the mangrove-derived endophytic fungus Penicillium janthinellum HDN13-309. The structures were elucidated through extensive NMR spectroscopic and physical data. The absolute configurations of com ...
DOI:
10.1039/c7ra10389a

9. Penicisulfuranols A–F, Alkaloids from the Mangrove Endophytic Fungus Penicillium janthinellum HDN13-309

Author:
Zhu, Meilin,   et al.   ; Zhang, Xiaomin; Feng, Huimin; Dai, Jiajia; Li, Jing; Che, Qian; Gu, Qianqun; Zhu, Tianjiao; Li, Dehai;     Show all 9 Authors
Source:
Journal of natural products 2017 v.80 no.1 pp. 71-75
ISSN:
1520-6025
Subject:
Penicillium janthinellum; alkaloids; amino acids; chemical structure; cytotoxicity; endophytes; fungi; inhibitory concentration 50; spectral analysis; sulfur
Abstract:
... Six new epipolythiodioxopiperazine (ETP) alkaloids, penicisulfuranols A–F (1–6), were isolated from the mangrove endophytic fungus Penicillium janthinellum HDN13-309. All structures including absolute configurations were elucidated on the basis of comprehensive spectroscopic data and ECD calculations. They belong to the unusual family of ETPs containing sulfur atoms on both α- and β-positions of a ...
DOI:
10.1021/acs.jnatprod.6b00483

10. Campyridones A–D, pyridone alkaloids from a mangrove endophytic fungus Campylocarpon sp. HDN13-307

Author:
Zhu, Meilin,   et al.   ; Zhang, Xiaomin; Feng, Huimin; Che, Qian; Zhu, Tianjiao; Gu, Qianqun; Li, Dehai;     Show all 7 Authors
Source:
Tetrahedron 2016 v.72 pp. 5679-5683
ISSN:
0040-4020
Subject:
alkaloids; biochemical pathways; chemical reactions; chemical structure; cytotoxicity; endophytes; fungi; inhibitory concentration 50; new family; spectroscopy
Abstract:
... Two pairs of epimers, campyridones A and B (1 and 2) and campyridones C and D (3 and 4), were isolated from the mangrove endophytic fungus Campylocarpon sp. HDN13-307, as well as the biogenetically related known ilicicolin H (5). Their structures including absolute configurations were elucidated on the basis of the spectroscopic analysis and ECD calculations. The new compounds 1–4 possess unpreced ...
DOI:
10.1016/j.tet.2016.07.080

11. Effects of Sulfate Application on Inhibiting Accumulation and Alleviating Toxicity of Arsenic in Panax notoginseng Grown in Arsenic-Polluted Soil

Author:
Zhu, Meilin,   et al.   ; Zeng, Xiancai; Jiang, Yanxue; Fan, Xiaoting; Chao, Sihong; Yang, Yue; Liu, Jianwei; Cao, Hongbin;     Show all 8 Authors
Source:
Water, air, and soil pollution 2016 v.227 no.5 pp. 148
ISSN:
0049-6979
Subject:
Panax notoginseng; arsenic; fertilizers; medicinal plants; peroxidase; planting; pot culture; roots; saponins; soil; sulfates; superoxide dismutase; toxicity
Abstract:
... Panax notoginseng (P. notoginseng) is a well-known traditional Chinese medicinal herb. Due to elevated arsenic (As) levels in some planting area, P. notoginseng and its derivatives are contaminated, and the As concentration in these products exceeds the standard limit (As concentration < 2 mg/kg). In this study, the effects of sulfate (S) application on As uptake and the physicological response of ...
DOI:
10.1007/s11270-016-2836-9

12. Cadmium accumulation in Panax notoginseng: levels, affecting factors and the non-carcinogenic health risk

Author:
Zhu, Meilin,   et al.   ; Jiang, Yang; Cui, Bin; Jiang, Yanxue; Cao, Hongbin; Zhang, Wensheng;     Show all 6 Authors
Source:
Environmental geochemistry and health 2016 v.38 no.2 pp. 423-435
ISSN:
0269-4042
Subject:
Monte Carlo method; Panax notoginseng; World Health Organization; acceptable daily intake; cadmium; diet; females; herbal medicines; males; men; pH; regression analysis; risk; roots; women; zinc; China
Abstract:
... Cadmium (Cd) contamination has been reported to be a problem for the safe usage of Panax notoginseng (Sanchi); thus, it is necessary to elucidate the Cd accumulation in Sanchi and to assess its associated health risk. Samples were collected from major producing areas in Yunnan, China. The average concentration of Cd in Sanchi was 0.43 mg/kg, which exceeds the standard level for herbal medicine in ...
DOI:
10.1007/s10653-015-9728-6

13. Evidence on the Adaptive Recruitment of Chinese Cork Oak (<i>Quercus variabilis</i> Bl.): Influence on Repeated Germination and Constraint Germination by Food-Hoarding Animals

Author:
Zhu, Meilin,   et al.   ; Zhang, Yifeng; Shi, Yuhua; Sichilima, Alfred M; Lu, Jiqi;     Show all 5 Authors
Source:
Forests 2016 v.7 no.2
ISSN:
1999-4907
Subject:
Apodemus; Quercus variabilis; buried seeds; drought; forest restoration; forest succession; fruits; models; predation; rodents; roots; seed germination; seed storage; seedlings; species recruitment; temperate forests; viability; China
Abstract:
... In drought temperate forest, seedling recruitment is highly dependent on seed burial by native animal dispersers. To prolong seed storage, animals often take measures to impede seed germination. Aiming to understand the strategic balance between the natural seed germination and the role played by animals in the constraint germination procedures, we investigated the stages on the germinated acorns ...
DOI:
10.3390/f7020047

14. Neosartoryadins A and B, Fumiquinazoline Alkaloids from a Mangrove-Derived Fungus Neosartorya udagawae HDN13-313

Author:
Zhu, Meilin,   et al.   ; Yu, Guihong; Zhou, Guoliang; Wang, Wei; Zhu, Tianjiao; Gu, Qianqun; Li, Dehai;     Show all 7 Authors
Source:
Organic letters 2016 v.18 no.2 pp. 244-247
ISSN:
1523-7052
Subject:
Neosartorya; alkaloids; chemical reactions; chemical structure; endophytes; fungi; inhibitory concentration 50; viruses
Abstract:
... Neosartoryadins A (1) and B (2), both with a unique 6/6/6/5 quinazoline ring system connected directly to a 6/5/5 imidazoindolone ring, together with three biogenetically related compounds 3–5, were isolated from the endophytic fungus Neosartorya udagawae HDN13-313. The absolute configurations of new compounds 1–4 were established. Compounds 1 and 2 displayed anti-influenza virus A (H1N1) activiti ...
DOI:
10.1021/acs.orglett.5b02964

15. Warming and wetting climate during last century revealed by an ice core in northwest Tibetan Plateau

Author:
Zhu, Meilin,   et al.   ; Deji,; Yao, Tandong; Yang, Xiaoxin; Xu, Baiqing; Zhao, Huabiao; Li, Jiule; Li, Zhen; Wu, Guangjian; Yao, Ping; You, Chao; Wang, Mo; Qu, Dongmei; Li, Quanlian;     Show all 14 Authors
Source:
Palaeogeography, palaeoclimatology, palaeoecology 2017
ISSN:
0031-0182
Subject:
cesium; climate; climate change; glaciers; ice; meteorological data; monsoon season; oxygen; radionuclides; seasonal variation; temperature; China
Abstract:
... Glaciers on the Tibetan Plateau (TP) exist in different states of extension and retreat, responding to the westerly winds and Indian monsoon. However, few studies to-date have focused on climate change in the westerlies-dominated northwest TP. Here, we report an ice core climate record during the last century retrieved from the Kuokuosele (KKSL) Glacier in the westerlies-dominated eastern Pamir, n ...
DOI:
10.1016/j.palaeo.2017.09.009

16. Identification of the sources of metals and arsenic in river sediments by multivariate analysis and geochemical approaches

Author:
Zhu, Meilin,   et al.   ; Cui, Bin; Jiang, Yang; Jiang, Yanxue; Cao, Hongbin;     Show all 5 Authors
Source:
Journal of soils and sediments 2014 v.14 no.8 pp. 1456-1468
ISSN:
1439-0108
Subject:
anthropogenic activities; arsenic; bedrock; cadmium; chromium; copper; fractionation; ionization; isotopes; lead; mercury; mining; multivariate analysis; rivers; sediment contamination; sediments; soil; spectrometers; zinc; China
Abstract:
... PURPOSE: Frequent mining activities and higher background values in soil have led to the contamination of the sediments of some rivers in southwest China by several metals and arsenic (As). This study combined multivariate analysis with geochemical approaches to differentiate mining activity from other sources, which may aid to evaluate the effectiveness of reducing mining release. MATERIALS AND M ...
DOI:
10.1007/s11368-014-0930-4

17. Levels of arsenic pollution in daily foodstuffs and soils and its associated human health risk in a town in Jiangsu Province, China

Author:
Zhu, Meilin,   et al.   ; Jiang, Yanxue; Zeng, Xiancai; Fan, Xiaoting; Chao, Sihong; Cao, Hongbin;     Show all 6 Authors
Source:
Ecotoxicology and environmental safety 2015 v.122 pp. 198-204
ISSN:
0147-6513
Subject:
arsenic; bioavailability; crabs; eggs; emissions; females; fertilizers; fish; fruits; geophagia; human health; industry; ingestion; males; neoplasms; paddies; pesticides; pollution; pork; rice; risk; rural areas; shrimp; sludge; soil; uncertainty; vegetables; water management; China
Abstract:
... The development of industries in rural areas can aggravate the arsenic (As) contamination of the local environment, which may pose unacceptable health risks to the local residents. This paper estimated the health risk posed by inorganic As (iAs) to residents via ingestion of soil, skin contact with soil and consumption of foodstuffs in a typical rural- industrial developed town in southern Jiangsu ...
DOI:
10.1016/j.ecoenv.2015.07.018

18. Determination of the Heavy Metal Levels in Panax notoginseng and the Implications for Human Health Risk Assessment

Author:
Zhu, Meilin,   et al.   ; Jiang, Yang; Cui, Bin; Jiang, Yanxue; Cao, Hongbin; Zhang, Wensheng;     Show all 6 Authors
Source:
Human and ecological risk assessment 2015 v.21 no.5 pp. 1218-1229
ISSN:
1549-7860
Subject:
Oriental traditional medicine; Panax notoginseng; United States Environmental Protection Agency; World Health Organization; acceptable daily intake; arsenic; carcinogenicity; chromium; copper; health hazards; heavy metals; human health; lead; nickel; plantations; risk; risk assessment; zinc
Abstract:
... High levels of heavy metals in Panax notoginseng (Sanchi), a valued traditional Chinese medicine, have drawn increasing concern regarding the safe usage of Sanchi preparations. Here, we measured the concentrations of six heavy metals in Sanchi samples from 20 major plantations, investigated the pharmaceutical processes and usages of Sanchi preparations, and assessed the associated potential health ...
DOI:
10.1080/10807039.2014.957942

19. Methods for assessing regional glacial lake variation and hazard in the southeastern Tibetan Plateau: a case study from the Boshula mountain range, China

Author:
Zhu, Meilin,   et al.   ; Wang, Weicai; Yao, Tandong; Yang, Wei; Joswiak, Daniel;     Show all 5 Authors
Source:
Environmental earth sciences 2012 v.67 no.5 pp. 1441-1450
ISSN:
1866-6280
Subject:
case studies; equipment; floods; geographic information systems; glaciers; global warming; lakes; models; remote sensing; surveys; China
Abstract:
... Glaciers on the Tibetan Plateau are undergoing an accelerating retreat under climatic warming, with the immediate result of glacial lake outburst floods (GLOFs) becoming increasingly frequent. Glacial lakes in the southeast of the Tibetan Plateau are densely distributed. Due to the difficulties associated with field investigations of glacial lakes, including remote locations and harsh weather cond ...
DOI:
10.1007/s12665-012-1589-z

20. The toxicity of cadmium (Cd2+) towards embryos and pro-larva of soldatov's catfish (Silurus soldatovi)

Author:
Zhu, Meilin,   et al.   ; Zhang, Hui; Cao, Hongbin; Meng, Yaobin; Jin, Guanghai;     Show all 5 Authors
Source:
Ecotoxicology and environmental safety 2012 v.80 pp. 258-265
ISSN:
0147-6513
Subject:
Silurus; adverse effects; cadmium; catfish; developmental stages; egg quality; embryogenesis; field experimentation; lethal concentration 50; mortality; river water; toxicity
Abstract:
... A six-day static-renewal toxicity test was performed to determine the influences of cadmium on the development of embryos of soldatov's catfish (Silurus soldatovi). The median lethal concentration (LC50) value and median effective concentration (EC50, i.e., the total adverse effects, including developmental defects and mortality) were calculated to be 2740 and 133μg/L, respectively, when cadmium w ...
DOI:
10.1016/j.ecoenv.2012.03.013