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- Zhu, Wenyong, et al. Show all 8 Authors
- Biochemical and biophysical research communications 2019 v.512 no.2 pp. 319-325
- agonists; alcohol drinking; aldehyde dehydrogenase; atherosclerosis; cell senescence; dose response; endothelium; ethanol; mice; protective effect; resveratrol
- ... Moderate alcohol consumption has been shown to reduce atherosclerosis-associated diseases. As shown in our earlier works, ethanol has a dose-dependent protective effects against endothelial cellular senescence by activating aldehyde dehydrogenase 2 (ALDH2) in vitro. However, whether ethanol administration possesses anti-atherosclerosis properties and whether ALDH2 is involved in the underlying mec ...