PubAg

Main content area

You searched for: Author "Zingue, Stéphane" Remove constraint Author: "Zingue, Stéphane"
Start Over

Search

11  Search Results

1 - 11 of 11
Number of results to display per page

Search Results

1. Cytotoxicity, antiprotozoal, and anti‐inflammatory activities of eight curry powders and comparison of their UPLC‐ESI‐QTOF‐MS chemical profiles

Author:
Zingue, Stephane,   et al.   ; Sandjo, Louis P; dos Santos Nascimento, Marcus VP; de Moraes, Milene H; Vicente, Geison; Amoah, Solomon KS; Dalmarco, Eduardo M; Frode, Tania S; Creczynski‐Pasa, Tânia B; Steindel, Mario;     Show all 10 Authors
Source:
Journal of the science of food and agriculture 2019 v.99 no.6 pp. 2987-2997
ISSN:
0022-5142
Subject:
Leishmania amazonensis; Trypanosoma cruzi; anti-inflammatory activity; antileishmanial properties; antiparasitic agents; apoptosis; chemical composition; condiments; curry; cytotoxicity; enzyme activity; ionization; leukocytes; liquids; mass spectrometry; metabolites; models; myeloperoxidase; nitrogen oxides; parasites; pleurisy; powders; Central Asia
Abstract:
... BACKGROUND: Curry powder is a blend of spices that is extensively consumed worldwide and mainly in Central Asia. Its preparation is strictly related to each locality and, because of the health benefits of its constituents, eight commercial forms of this condiment were biologically and chemically investigated. This study aimed to compare their chemical profile as well as their anti‐inflammatory, cy ...
DOI:
10.1002/jsfa.9512

2. The hydro-ethanolic extract of Acacia seyal (Mimosaceae) stem barks induced death in an ER-negative breast cancer cell line by the intrinsic pathway of apoptosis and inhibited cell migration

Author:
Zingue, Stephane,   et al.   ; Michel, Thomas; Cisilotto, Julia; Tueche, Alain Brice; Ndinteh, Derek Tantoh; Mello, Leônidas João; Njamen, Dieudonné; Creczynski-Pasa, Tânia Beatriz;     Show all 8 Authors
Source:
Journal of ethnopharmacology 2018 v.223 pp. 41-50
ISSN:
0378-8741
Subject:
Acacia seyal; antineoplastic activity; antineoplastic agents; apoptosis; breast neoplasms; breasts; caspases; cell cycle checkpoints; cell lines; cell movement; cytotoxicity; death; enzyme activity; flora; flow cytometry; membrane potential; metastasis; mitochondria; mitochondrial membrane; necrosis; neoplasm cells; protein content; traditional medicine; Cameroon
Abstract:
... Despite the significant developments occurring in the treatment of cancer, it still remains the second deadly disease, responsible for 8.2 million deaths every year. Various natural substances have been studied for active molecules of tumor suppression in the past and the tropical flora, by its diversity, continues to provide new antitumor drugs. Acacia seyal is a plant used in Cameroonian traditi ...
DOI:
10.1016/j.jep.2018.05.021

3. Correction to: Ficus sycomorus extract reversed behavioral impairment and brain oxidative stress induced by unpredictable chronic mild stress in rats

Author:
Zingue, Stéphane,   et al.   ; Foyet, HarquinSimplice; Deffo, SergeTchinda; Yewo, PascalineKoagne; Antioch, Iulia; Asongalem, EmmanuelAcha; Kamtchouing, Pierre; Ciobica, Alin;     Show all 8 Authors
Source:
BMC complementary and alternative medicine 2017 v.17 no.1 pp. 552
ISSN:
1472-6882
Subject:
Ficus sycomorus; alternative medicine; brain; oxidative stress; rats
Abstract:
... CORRECTION: After the publication of this article [1] it came to our attention that Harquin Simplice Foyet was incorrectly included as Harquin Simplice Harquin Foyet. The corrected name is included in the author list. The original article was updated. ...
DOI:
10.1186/s12906-017-2069-5
PubMed:
29284460
PubMed Central:
PMC5747076

4. Ficus sycomorus extract reversed behavioral impairment and brain oxidative stress induced by unpredictable chronic mild stress in rats

Author:
Zingue, Stéphane,   et al.   ; Foyet, HarquinSimplice; Tchinda Deffo, Serge; Koagne Yewo, Pascaline; Antioch, Iulia; Asongalem, Emmanuel Acha; Kamtchouing, Pierre; Ciobica, Alin;     Show all 8 Authors
Source:
BMC complementary and alternative medicine 2017 v.17 no.1 pp. 502
ISSN:
1472-6882
Subject:
Ficus sycomorus; alternative medicine; antidepressants; antioxidant activity; antioxidants; anxiety; bark; brain; enzymes; flavonoids; glutathione; lipid content; lipid peroxidation; liquid chromatography; malondialdehyde; mass spectrometry; memory disorders; oxidative stress; oxygen consumption; pathophysiology; rats; risk factors; sucrose; swimming
Abstract:
... BACKGROUND: Stress, regardless of its nature is nowadays recognized as one of the major risk factors for neuropsychiatric diseases, such as mood and anxiety disorders. The brain compared with other organs is more vulnerable to oxidative damage mainly due to its high rate of oxygen consumption, abundant lipid content, and relative insufficiency of antioxidant enzymes. Thus, the identification of ne ...
DOI:
10.1186/s12906-017-2012-9
PubMed:
29179735
PubMed Central:
PMC5704586

5. Millettia macrophylla (Fabaceae) phenolic fraction prevents differentiation of 3T3-L1 adipocytes and the increased risks of cardiovascular diseases in ovariectomized rats

Author:
Zingue, Stéphane,   et al.   ; do Carmo, Ícaro Andrade Rodrigues; Tchoumtchoua, Job; Tchoupang, Edwige Nana; Bratti, Letícia de Oliveira Souza; Mora, Tamara Dal; Halabalaki, Maria; Njamen, Dieudonné; Creczynski-Pasa, Tânia Beatriz; Filippin-Monteiro, Fabíola Branco;     Show all 10 Authors
Source:
Journal of ethnopharmacology 2018 v.222 pp. 87-98
ISSN:
0378-8741
Subject:
Millettia; abdominal fat; adipocytes; antioxidant activity; aorta; body weight changes; cardiovascular diseases; catalase; daidzein; enzyme activity; estrogenic properties; estrogens; glucose; glutathione; hyperlipidemia; interleukin-6; lipid composition; lipid metabolism; malondialdehyde; nitric oxide; ovariectomy; plant estrogens; postmenopause; protective effect; rats; risk factors; superoxide dismutase; traditional medicine; vasodilator agents; Cameroon
Abstract:
... A prolonged estrogen deficiency alters lipid metabolism and increases risks of cardiovascular diseases. Phytoestrogens, naturally occurring compounds with estrogenic properties are reported to have cardiovascular protective effects. Millettia macrophylla used in the Cameroonian traditional system to treat physiological disorders related to menopause, was previously reported to have estrogenic effe ...
DOI:
10.1016/j.jep.2018.04.046

6. Safety evaluation (acute and sub-acute studies) of the aqueous extract of the leaves of Myrianthus arboreus P. Beauv. (Cecropiaceae) in Wistar rats

Author:
Zingue, Stéphane,   et al.   ; Awounfack, Charline Florence; Ateba, Sylvin Benjamin; Mouchili, Oumarou Riepouo; Njamen, Dieudonné;     Show all 5 Authors
Source:
Journal of ethnopharmacology 2016 v.194 pp. 169-178
ISSN:
0378-8741
Subject:
Urticaceae; acute toxicity; alanine transaminase; blood serum; cholesterol; creatinine; diarrhea; dietary exposure; erythrocyte count; female fertility; females; forests; guidelines; hematocrit; hemoglobin; high density lipoprotein; leaf extracts; leaves; lethal dose 50; leukocyte count; lymphocytes; males; medicinal plants; mortality; neoplasms; oral administration; rats; safety assessment; seminal vesicles; traditional medicine; triacylglycerols; Africa
Abstract:
... Myrianthus arboreus P. Beauv (Cecropiaceae) is a medicinal plant distributed in forests and damp places of tropical Africa. Its leaves are widely used as food and/or for the treatment of various ailments including dysmenorrhoea, female infertility, tumors and diarrhea. However, to the best of our knowledge, no safety assessment of this plant has been reported yet.The present study aimed at evaluat ...
DOI:
10.1016/j.jep.2016.08.052

7. Estrogen-like and tissue-selective effects of 7-methoxycoumarin from Ficus umbellata (Moraceae): an in vitro and in vivo study

Author:
Zingue, Stéphane,   et al.   ; Michel, Thomas; Nde, ChantalBeatrice Magne; Njuh, AmstrongNang; Cisilotto, Julia; Ndinteh, DerekTantoh; Clyne, Colin; Fernandez, Xavier; Creczynski-Pasa, TâniaBeatriz; Njamen, Dieudonné;     Show all 10 Authors
Source:
BMC complementary and alternative medicine 2017 v.17 no.1 pp. 383
ISSN:
1472-6882
Subject:
Ficus; abdominal fat; alternative medicine; animal models; aromatase; blood lipids; bone density; cell proliferation; epithelium; estradiol; estrogenic properties; histology; in vitro studies; in vivo studies; lipid composition; medicinal plants; metabolites; neoplasms; ovariectomy; plant extracts; rats; reporter genes; umbelliferones; uterus; vagina
Abstract:
... BACKGROUND: Ficus umbellata is a medicinal plant previously shown to endow estrogenic properties. Its major component was isolated and characterized as 7-methoxycoumarin (MC). Noteworthy, coumarins and the respective active metabolite 7-hydroxycoumarin analogs have shown aromatase inhibitory activity, which is of particular interest in the treatment of estrogen-dependent cancers. The present work ...
DOI:
10.1186/s12906-017-1895-9
PubMed:
28768532
PubMed Central:
PMC5541738

8. Ethanol-extracted Cameroonian propolis exerts estrogenic effects and alleviates hot flushes in ovariectomized Wistar rats

Author:
Zingue, Stéphane,   et al.   ; Nde, ChantalBeatrice Magne; Michel, Thomas; Ndinteh, DerekTantoh; Tchatchou, Jules; Adamou, Moïse; Fernandez, Xavier; Fohouo, Fernand-NestorTchuenguem; Clyne, Colin; Njamen, Dieudonné;     Show all 10 Authors
Source:
BMC complementary and alternative medicine 2017 v.17 no.1 pp. 65
ISSN:
1472-6882
Subject:
adults; alternative medicine; amenorrhea; caffeic acid; dose response; epithelium; estrogen receptors; estrogenic properties; humans; kidney cells; mammary glands; menopause; ovariectomy; plant estrogens; propolis; protein content; rats; reporter genes; scientists; uterus; women; Cameroon
Abstract:
... BACKGROUND: Since the biological properties of propolis depend to the plants that can be found in a specific region, propolis from unexplored regions attracts the attention of scientists. Ethanolic extract of Cameroonian propolis (EEP) is used to treat various ailments including gynecological problems and amenorrhea. Since there were no scientific data to support the above claims, the present stud ...
DOI:
10.1186/s12906-017-1568-8
PubMed:
28109283
PubMed Central:
PMC5477728

9. Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth (Fabaceae): towards a better understanding of its underlying mechanisms

Author:
Zingue, Stéphane,   et al.   ; Tchoumtchoua, Job; Ntsa, Dieudonnée Mireille; Sandjo, Louis Pergaud; Cisilotto, Julia; Nde, Chantal Beatrice Magne; Winter, Evelyn; Awounfack, Charline Florence; Ndinteh, Derek Tantoh; Clyne, Colin; Njamen, Dieudonné; Halabalaki, Maria; Creczynski-Pasa, Tânia Beatriz;     Show all 13 Authors
Source:
BMC complementary and alternative medicine 2016 v.16 no.1 pp. 421
ISSN:
1472-6882
Subject:
Millettia; adults; alternative medicine; chromatography; cytotoxicity; epithelium; estrogenic properties; methanol; nuclear magnetic resonance spectroscopy; osteoporosis; ovariectomy; postmenopause; rats; reporter genes; secondary metabolites; traditional medicine
Abstract:
... BACKGROUND: Millettia macrophylla was previously reported to have estrogenic effects and to prevent postmenopausal osteoporosis in Wistar rats. So, the study deals with the identification of its secondary metabolites and the evaluation of their estrogenicity and cytotoxicity toward tumoural cells. Thus, 13 known compounds were obtained from successive chromatographic columns and identified by NMR ...
DOI:
10.1186/s12906-016-1385-5
PubMed:
27784319
PubMed Central:
PMC5396542

10. Estrogenic effects of Ficus umbellata Vahl. (Moraceae) extracts and their ability to alleviate some menopausal symptoms induced by ovariectomy in Wistar rats

Author:
Zingue, Stéphane,   et al.   ; Michel, Thomas; Tchatchou, Jules; Chantal Beatrice Magne, Nde; Winter, Evelyn; Monchot, André; Awounfack, Charline Florence; Djiogue, Sefirin; Clyne, Colin; Fernandez, Xavier; Creczynski-Pasa, Tânia Beatriz; Njamen, Dieudonné;     Show all 12 Authors
Source:
Journal of ethnopharmacology 2016 v.179 pp. 332-344
ISSN:
0378-8741
Subject:
Ficus; adults; amenorrhea; coumarin; dose response; epithelium; estrogen receptors; estrogenic properties; fractionation; humans; kidneys; medicinal plants; menopause; methanol; ovariectomy; protein content; rats; reporter genes; traditional medicine; Cameroon
Abstract:
... Ficus umbellata Vahl. (Moraceae) is a medicinal plant used in Cameroon to treat amenorrhea as well as other physiological disorders related to menopause.In order to justify scientifically its traditional use, the estrogen-like properties of the aqueous (AE) and methanol (MeOH) extracts of F. umbellata were investigated.In vitro, the ability of different extracts of F. umbellata to activate estroge ...
DOI:
10.1016/j.jep.2016.01.004

11. Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo

Author:
Zingue, Stéphane,   et al.   ; Cisilotto, Julia; Tueche, Alain Brice; Bishayee, Anupam; Mefegue, Francine Azegha; Sandjo, Louis Pergaud; Magne Nde, Chantal Beatrice; Winter, Evelyn; Michel, Thomas; Ndinteh, Derek Tantoh; Awounfack, Charline Florence; Silihe, Kevine Kamga; Melachio Tanekou, Tito Tresor; Creczynski-Pasa, Tânia Beatriz; Njamen, Dieudonné;     Show all 15 Authors
Source:
Journal of ethnopharmacology 2016 v.190 pp. 183-199
ISSN:
0378-8741
Subject:
Crateva adansonii; DNA; DNA fingerprinting; animal use replacement; asthma; body weight; breast neoplasms; carcinogenesis; constipation; cytotoxicity; females; flavonols; histology; human cell lines; hyperplasia; in vitro studies; in vivo studies; laboratory animals; lethal dose 50; lignans; liquids; mammary glands; methanol; methylene chloride; models; neoplasm cells; postmenopause; rats; sesquiterpenoids; snake bites; spectroscopy; tamoxifen; traditional medicine; Cameroon
Abstract:
... Crateva adansonii DC is a plant traditionally used in Cameroon to treat constipation, asthma, snakebites, postmenopausal complaints and cancers.The anticancer potential of the dichloromethane/methanol extract of C. adansonii stem barks was investigated using human breast cancer cell and 7,12 dimethylbenz(a)anththracene (DMBA)-induced mammary tumorigenesis model in rats.The cytotoxicity of C. adans ...
DOI:
10.1016/j.jep.2016.06.004