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aminoacidmetabolism, etc ; cryoprotectants; energy metabolism; frozen dough; frozen storage; glycerol; hydrocolloids; ice; lipid metabolism; maltodextrins; metabolomics; trehalose; viability; yeasts; Show all 14 Subjects
Abstract:
... The formation and growth of ice crystals are widely acknowledged to cause damage to different substances and we found short-clustered maltodextrin (SCMD) could alleviate the quality deterioration of frozen dough in previous research. But how SCMD interacts with dough components such as yeast is poorly understood. Here, we analyze the ice-recrystallization-inhibition (IRI) activity of SCMD and prov ...
... The inhomogeneity of plastisphere and soil may result in different microbial communities, thus potentially affecting soil functions. Biodegradable plastics offer an alternative to conventional plastics, nevertheless, the inadequate end-of-life treatment of biodegradable plastics may release more microplastics. Herein, we collected PE and PBAT/PLA microplastics in plastic-mulching farmland in Hebei ...
aminoacidmetabolism, etc ; adenosine triphosphate; biosynthesis; energy; energy metabolism; food chemistry; fruit quality; fruits; mechanical damage; metabolomics; secondary metabolites; transportation; vibration; Show all 13 Subjects
Abstract:
... Mechanical damage caused by vibration during transportation can destroy organization structure and reduce the fruit quality. The objective was to reveal the mechanism of hypobaric treatment on energy metabolism in vibration-injured 'Huangguan' pears based on metabolomics. Results showed that hypobaric treatment delayed the decline of adenosine triphosphate (ATP) content, energy charge (EC), H⁺-ATP ...
... Resistant starch (RS) has caught much attention for its potential to exert a beneficial impact on intestine and certain members of its resident microbiota. In this study, we examined how dietary RS promotes intestinal barrier in meat ducks by microbiome-metabolomics analysis. Ducklings were fed corn-soybean basal diet or RS diet. Dietary RS improved intestinal morphology and enhanced barrier funct ...
... With the rapid development of hydropower facility construction, the total dissolved gas (TDG) generated by dam discharge is seriously threatening the survival of fish and has become an ecological environmental issue of global concern. However, how TDG affects fish physiology and the underlying molecular mechanism remain poorly known. In this study, Acipenser dabryanus, an ancient living fossil tha ...
... Water quality is closely related to the nutritional and sensory qualities of grass carp, which has the largest aquaculture production among freshwater fishes. The purpose of this study was to explore the effects of nitrite and nitrate on the growth performance, nutrition composition and muscle flavor-associated metabolites of grass carp through an exposure experiment with varying concentrations (n ...
Moha Esmaeili; Chris G. Carter; Richard Wilson; Seumas P. Walker; Matthew R. Miller; Andrew R. Bridle; Tim Young; Andrea C. Alfaro; Olivier Laroche; Jane E. Symonds
aminoacidmetabolism, etc ; Oncorhynchus tshawytscha; aquaculture; blood plasma; catabolism; data collection; feed conversion; fish; genes; glucose; glutathione; isoleucine; leucine; liver; metabolites; metabolomics; multiomics; muscles; phenotype; phenylalanine; protein degradation; protein synthesis; proteolysis; proteomics; pyruvic acid; seawater; tryptophan; tyrosine; valine; Show all 29 Subjects
Abstract:
... Feed efficiency (FE) is a critical phenotype for aquaculture sustainability, yet it is poorly understood at the molecular level. In this study, the molecular basis of FE was investigated using a multi-omics approach to integrate proteome-level data and metabolites associated with differences in feed efficiency. To achieve this, Chinook salmon (Oncorhynchus tshawytscha) were reared in seawater and ...
... Cadmium (Cd) induces severe soil pollution worldwide and exerts adverse effects on paddy field arthropods. Spiders grant a novel perspective to assess the Cd-induced toxicity, yet the impacts of long-term Cd stress on spider silk glands and its underlying mechanism remain elusive. The study showed that Cd stress enervated the antioxidant system in the spider Pardosa pseudoannulata, manifested as t ...
aminoacidmetabolism, etc ; fermentation; fermenters; pH; sludge; temperature; Show all 6 Subjects
Abstract:
... The pH control to promote short-chain fatty acids (SCFAs) production during anaerobic alkaline fermentation basically focused on constant pH control. In this study, a simple and consumption-reducing intermittent pH control strategy at moderate temperature (23 ± 2 °C) was investigated with adjusting pH to 10 when naturally reduced to 8. The intermittent pH control strategy could alleviate the inhib ...
aminoacidmetabolism, etc ; absorption; biomarkers; detection limit; diet; fluorescence; humans; immunoassays; labor; phenylketonuria; urine; Show all 11 Subjects
Abstract:
... Phenylketonuria (PKU) is the most common inborn error of amino acid metabolism caused by an inherited deficiency in L-phenylalanine-4-hydroxylase (PAH) activity. It is usually controlled by diet and monitored regularly with markers, as PKU is not curable. However, conventional methods for target biomarker analysis are invasive and labor intensive. Here, we report a rapid and sensitive, mimetic imm ...
aminoacidmetabolism, etc ; blood serum; colitis; colon; glycolipids; inflammation; intestinal microorganisms; metabolites; pollution; tebuconazole; Show all 10 Subjects
Abstract:
... As a common fungicide, tebuconazole are ubiquitous in the natural environment and poses many potential risks. In this study, we examined the effects of exposure to tebuconazole on colitis in mice and explored its underlying mechanism. Specifically, exposure to tebuconazole could cause structural damage and inflammatory cell infiltration in colon tissue, activate the expression of inflammation-rela ...
aminoacidmetabolism, etc ; amino acids; autophagy; biochemical pathways; biotechnology; homeostasis; lipid metabolism; secondary metabolites; Show all 8 Subjects
Abstract:
... Amino acids are the building blocks of protein, promoting the balance between growth and lipid synthesis. However, the accumulation of microbial lipids involves multiple pathways, which requires the analysis of the global cellular metabolic network in which amino acid metabolism is involved. This review illustrates the dependence patterns of intracellular amino acids and lipids of oleaginous eukar ...
Steven A. van der Hoek; Matej Rusnák; Guokun Wang; Lyubomir Dimitrov Stanchev; Luana de Fátima Alves; Mathew M. Jessop-Fabre; Kalaivani Paramasivan; Irene Hjorth Jacobsen; Nikolaus Sonnenschein; José L. Martínez; Behrooz Darbani; Douglas B. Kell; Irina Borodina
aminoacidmetabolism, etc ; Saccharomyces cerevisiae; amino acids; antioxidants; batch fermentation; biosynthesis; carbon; glucose; synthesis; yeasts; Show all 10 Subjects
Abstract:
... Ergothioneine (ERG) is an unusual sulfur-containing amino acid. It is a potent antioxidant, which shows great potential for ameliorating neurodegenerative and cardiovascular diseases. L-ergothioneine is rare in nature, with mushrooms being the primary dietary source. The chemical synthesis process is complex and expensive. Alternatively, ERG can be produced by fermentation of recombinant microorga ...
aminoacidmetabolism, etc ; Saccharomyces cerevisiae; biochemical pathways; biosynthesis; coumaric acids; indigenous species; kava; oxidoreductases; yeasts; Show all 9 Subjects
Abstract:
... Plant styrylpyrones exerting well-established neuroprotective properties have attracted increasing attention in recent years. The ability to synthesize each individual styrylpyrone in engineered microorganisms is important to understanding the biological activity of medicinal plants and the complex mixtures they produce. Microbial biomanufacturing of diverse plant-derived styrylpyrones also provid ...
aminoacidmetabolism, etc ; beers; biotechnology; fermentation; flavor; gravity; metabolites; metabolomics; pyruvic acid; stress tolerance; sugars; transcriptomics; Show all 12 Subjects
Abstract:
... The fermentation performance of yeast is the key of beer production. High gravity brewing is a commonly used technique in industrial lager beer production and it is environmentally friendly. Therefore, there has been extensive effort toward improving high gravity brewing. In this study, through transcriptomic and metabolomic analysis of two homologous lager yeasts, genes that relate to stress tole ...
aminoacidmetabolism, etc ; amino acids; anaerobic ammonium oxidation; biofilm; biosynthesis; energy; enzymes; lipids; metabolites; nitrogen; technology; Show all 11 Subjects
Abstract:
... Although amino acid (AA) metabolism is basis of bacterial activities, unique characteristics of its response to decreased temperatures are not fully understood. Achieving nitrogen removal rate of 130–150 mg N/ (L∙d), metabolic differences of anammox consortia between 35 °C and four decreased temperatures (15–30 °C) were revealed respectively. 0-11.4-fold abundance variation of marker metabolites e ...
aminoacidmetabolism, etc ; amino acids; ammonia; animal nutrition; indoles; intestinal microorganisms; intestines; metabolites; microbial communities; swine; Show all 10 Subjects
Abstract:
... With the rapid development of sequencing technology, research on pigs has focused on intestinal microbes. Accumulating evidence suggests that the metabolites of intestinal microbes are the key medium for interactions between microbes and the host. Amino acid metabolism is involved in the growth and immune processes of pigs. The gut microbes of pigs are heavily involved in the metabolism of amino a ...
aminoacidmetabolism, etc ; biomarkers; blood serum; chromatography; glucose; lipid metabolism; mass spectrometry; metabolites; metabolomics; pain; rheumatoid arthritis; Show all 11 Subjects
Abstract:
... Yaobitong capsule (YBTC) has been used for the prevention and treatment of inflammation-related lumbago and leg pain. However, its intervention mechanism still remains unclear. This study was aimed to evaluate the control efficiency of YBTC on adjuvant-induced rheumatoid arthritis (RA) rats by metabonomic method and to explore its possible anti-arthritis mechanism. Taking into account the complexi ...
aminoacidmetabolism, etc ; COVID-19 infection; Firmicutes; Moraxella; biomarkers; lipid metabolism; microbiome; nose; pathogenesis; species diversity; throat; Show all 11 Subjects
Abstract:
... In the prevalence of COVID-19, infection symptoms are different in children and adults. In this study to investigate the differences in the upper respiratory tract microbiome profile between healthy children and adults and to explore which microbiome protect them from COVID-19. Thirty healthy children and 24 healthy adults were enrolled between October 2020 and January 2021. Nasal and throat swabs ...
aminoacidmetabolism, etc ; Acidocella; Clostridium; activated sludge; carbohydrate metabolism; chemical oxygen demand; fermentation; organic matter; solubilization; sorbitol; Show all 10 Subjects
Abstract:
... Polyoxyethylene dehydration sorbitol monooleate (polysorbate-80) pretreatment enhanced volatile fatty acids (VFAs) production of waste activated sludge (WAS) in acidogenic fermentation. The results showed that polysorbate-80 ameliorated WAS solubilization obviously with a soluble chemical oxygen demand (SCOD) increasing to 1536 mg/L within 4 h. Within 2 days of acidogenic fermentation, the maximal ...