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arrhythmia, etc ; cotton fabric; electrocardiography; research; Show all 4 Subjects
Abstract:
... Wearable electrocardiogram (ECG) systems should be comfortable, non-stigmatizing, and capable of producing high-quality data. Many different designs of wearable textile ECG systems have recently emerged. Some of them are not considered to be smart garments, whereas most of the others present only the electronic side of the system. Our research work introduces a comprehensive study for an improved ...
arrhythmia, etc ; anxiety; behavior; brain stem; scanners; Show all 5 Subjects
Abstract:
... Recently, we reported on a rare manifestation of respiratory sinus arrhythmia (RSA), namely the “switched-off” RSA (Rassler et al., 2018), also called negative RSA (nRSA). It was found in a minority of healthy persons during elevated fMRI-related anxiety characterized by slow spontaneous breathing and synchronous slow beat-to-beat interval (RRI) oscillations.From 23 healthy scanner naïve participa ...
arrhythmia, etc ; catheters; dogs; electric potential difference; etiology; radio waves; Show all 6 Subjects
Abstract:
... A 1.5-year-old, female-spayed mix-breed dog was presented with recurrent episodes of shaking and excessive panting attributed to drug-refractory ventricular arrhythmia (VA) characterized predominantly by incessant periods of ventricular bigeminy. The VA had a narrow QRS morphology, suggestive of an origin near the His bundle or fascicular system. Diagnostic evaluation found no structural heart dis ...
arrhythmia, etc ; least squares; principal component analysis; support vector machines; Show all 4 Subjects
Abstract:
... To evaluate the performance of the classic machine learning algorithms and the effectiveness of various features, the iterative algorithms (i.e., support vector machine (SVM), and least-squares SVM (LS-SVM)) and non-iterative algorithms (i.e., random forest (RF) and naive bayes (NB)) for six feature schemes were performed to classify the ECG recordings. The ECG recordings were initially filtered w ...
arrhythmia, etc ; animal diseases; consciousness; death; foams; mortality; poultry; swine; Show all 8 Subjects
Abstract:
... Animal disease preparedness plans including depopulation guidelines are paramount to prevent the spread of emerging infectious diseases but difficult to implement for swine under field conditions. However, water‐based foam (WBF) is currently an approved and successfully deployed depopulation methodology in poultry. Therefore, the reliability of WBF as a depopulation method and the effectiveness an ...
arrhythmia, etc ; curriculum; family and consumer science; poverty; sustainable development; Show all 5 Subjects
Abstract:
... The Swedish school subject Home Economics (HE) covers complex content to do with cooking and sustainable development, but is allocated relatively few hours. I draw on observations of HE lessons and interviews with teachers to show how experiences of time poverty can be conceptualized as arrhythmia in relation to the requirements of the curriculum, scheduling, cultural expectations, and the unpredi ...
arrhythmia, etc ; algorithms; data collection; electrocardiography; neural networks; songbirds; vocalization; wavelet; Show all 8 Subjects
Abstract:
... Classification and subsequent diagnosis of cardiac arrhythmias is an important research topic in clinical practice. Confirmation of the type of arrhythmia at an early stage is critical for reducing the risk and occurrence of cardiovascular events. Nevertheless, diagnoses must be confirmed by a combination of specialist experience and electrocardiogram (ECG) examination, which can lead to delays in ...
arrhythmia, etc ; biomarkers; drug development; equations; heart rate; moxifloxacin; risk; risk assessment; toxicology; Show all 9 Subjects
Abstract:
... Preclinical risk assessment of drug-induced arrhythmias is critical for drug development and relies on heart rate corrected QT interval (QT) prolongation as a biomarker for arrhythmia risk. However, the methods used to correct QT vary in complexity and don't account for all changes in the QT-rate relationship. Thus, we developed the novel Ratio QT correction method which characterizes that relatio ...
Praloy Chakraborty; Stéphane Massé; Mohammed Ali Azam; Catherine Thollon; Ahmed Niri; Patrick F.H. Lai; Muriel Bouly; Sheila Riazi; Kumaraswamy Nanthakumar
arrhythmia, etc ; action potentials; calcium; electric potential difference; models; rabbits; research; risk; ryanodine receptors; Show all 9 Subjects
Abstract:
... Proarrhythmic risk of conventional anti-arrhythmic agents is linked to unintended modulation of membrane voltage dynamics. We have demonstrated that the anti-fibrillatory effect of azumolene is mediated via stabilization of the hyperphosphorylated ryanodine receptor (RyR2), leading to attenuation of diastolic calcium leak. However, the concomitant effects on membrane voltage dynamics have not been ...
arrhythmia, etc ; coronary vessels; echocardiography; heart failure; hemodynamics; histology; infarction; mice; myocardial infarction; pathophysiology; therapeutics; Show all 11 Subjects
Abstract:
... Right ventricular infarction (RVI) is a common presentation in clinical practice. Severe RVI can lead to fatal hemodynamic dysfunction and arrhythmia. In contrast to the extensively used mouse myocardial infarction (MI) model generated by left coronary artery ligation, the RVI mouse model is rarely employed due to the difficulty associated with model generation. Research on the mechanisms and trea ...
arrhythmia, etc ; apoptosis; autophagy; high fat diet; infarction; ischemia; melatonin; mitochondria; oxidative stress; reperfusion injury; surgery; Show all 11 Subjects
Abstract:
... Although acute melatonin treatment effectively reduces cardiac ischemia/reperfusion (I/R) injury in lean rats by modulating melatonin receptor 2 (MT2), there is no information regarding the temporal effects of melatonin administration during cardiac I/R injury in prediabetic obese rats. Prediabetic obese rats induced by chronic consumption of a high-fat diet (HFD) were used. The rats underwent a c ...
... Our primary objective was to examine the extent to which moment-to-moment associations between preschool-aged children's behavior and maternal emotional support differed for mothers showing different levels of parasympathetic engagement. We used behavioral observations of maternal and child behavior and maternal changes in cardiac vagal tone assessed via respiratory sinus arrhythmia in 15-s interv ...
arrhythmia, etc ; German Shepherd; anesthesia; cardiac arrest; dogs; energy; epinephrine; magnesium sulfate; medicine; patent ductus arteriosus; patients; Show all 11 Subjects
Abstract:
... OBJECTIVE: To describe a case of successful return of spontaneous circulation in an anesthetized dog that developed spontaneous ventricular fibrillation during CPR that was refractory to multiple defibrillation attempts by utilizing pharmacological antiarrhythmic therapy. CASE SUMMARY: Cardiopulmonary arrest occurred during surgical preparation in a 1‐year‐old German Shepherd Dog under general ane ...
Tai Le; Jimmy Zhang; Anh H. Nguyen; Ramses Seferino Trigo Torres; Khuong Vo; Nikil Dutt; Juhyun Lee; Yonghe Ding; Xiaolei Xu; Michael P.H. Lau; Hung Cao
arrhythmia, etc ; Danio rerio; anesthetics; biosensors; data quality; drug therapy; electrocardiography; fish; heart rate; mutants; sodium; temperature; Show all 12 Subjects
Abstract:
... Zebrafish and their mutant lines have been extensively used in cardiovascular studies. In the current study, the novel system, Zebra II, is presented for prolonged electrocardiogram (ECG) acquisition and analysis for multiple zebrafish within controllable working environments. The Zebra II is composed of a perfusion system, apparatuses, sensors, and an in-house electronic system. First, the Zebra ...
... Calmodulin (CaM), a ubiquitous and highly conserved Ca²⁺-sensor protein involved in the regulation of over 300 molecular targets, has been recently associated with severe forms of lethal arrhythmia. Here, we investigated how arrhythmia-associated mutations in CaM localized at the C-terminal lobe alter the molecular recognition with Ryanodine receptor 2 (RyR2), specifically expressed in cardiomyocy ...
... This study aimed to characterize the clinical and histopathological features of arrhythmogenic right ventricular cardiomyopathy (ARVC) in English Bulldogs, American Bulldogs, and Bulldog-type mixed breed dogs and assess affected Bulldogs for a striatin gene mutation previously reported in Boxers with ARVC. Seventy-one Bulldogs fit the inclusion criteria. Genetic analysis was performed on five dogs ...
... This study assesses the effect of malnutrition on the in-hospital outcomes of patients with takotsubo cardiomyopathy (TCM).We performed a retrospective cohort analysis using the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes for a primary diagnosis of TCM from the National Inpatient Sample database (2016–2018). A concurrent diagnosis of malnutriti ...
arrhythmia, etc ; biosensors; calcium; cardiomyocytes; cardiotoxicity; drug therapy; drug toxicity; drugs; electrodes; heart failure; potassium; sodium; sodium channels; Show all 13 Subjects
Abstract:
... Unintended binding of small-molecule drugs to ion channels affects electrophysiological properties of cardiomyocytes and potentially leads to arrhythmia and heart failure. The waveforms of intracellular action potentials reflect the coordinated activities of cardiac ion channels and serve as a reliable means for assessing drug toxicity, but the implementation is limited by the low throughput of pa ...
arrhythmia, etc ; Iris domestica; RNA; auxins; circadian clocks; cryptochromes; flowers; genes; hypocotyls; phytochrome; research; scotophase; transcription (genetics); white light; Show all 14 Subjects
Abstract:
... The circadian clock can entrain to forced light-dark cycles by adjusting the phases and periods of flower opening and closing in ephemeral flowers. The responses of circadian rhythms to the same light conditions differ from species. However, the differences in internal genetic mechanisms underlying the different responses between species remain unclear. Iris domestica and I. dichotoma have ephemer ...
arrhythmia, etc ; Corydalis yanhusuo; Oriental traditional medicine; alkaloids; analgesia; analgesics; blood circulation; databases; lead; pain; prediction; sodium; sodium channels; Show all 13 Subjects
Abstract:
... Corydalis yanhusuo W. T. Wang, a traditional Chinese herbal medicine, has been used as an analgesic for thousands of years and it also promotes blood circulation. In this study, 33 Corydalis yanhusuo alkaloid active components were acquired from Traditional Chinese Medicine Database and Analysis Platform (TCMSP). A total of 543 pain-related targets, 1774 arrhythmia targets, and 642 potential targe ...