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1. A sensitive and selective terahertz sensor for the fingerprint detection of lactose

Author:
Han, Baojuan; Han, Zhanghua; Qin, Jianyuan; Wang, Yongmei; Zhao, Zongshan
Source:
Talanta 2019 v.192 pp. 1-5
ISSN:
0039-9140
Subject:
biochemical pathways,   etc   ; electric field; fructose; honors and awards; lactose; transmittance;     Show all 6 Subjects
Abstract:
... Special recognition to molecules is essential for many biochemical processes, thus highly sensitive sensing methods for molecule recognition are strongly demanded. Recently, metamaterials present a unique platform for sensing applications owing to their exotic properties. In the current work, a metamaterial sensor for enhanced fingerprint detection of lactose based on resonant coupling of plasmoni ...
DOI:
10.1016/j.talanta.2018.09.029

2. Brown and beige fat: From molecules to physiology Molecular and cell biology of lipids

Author:
Chondronikola, Maria; Sidossis, Labros S.
Source:
Biochimica et biophysica acta 2019 v.1864 no.1 pp. 91-103
ISSN:
1388-1981
Subject:
biochemical pathways,   etc   ; brown adipose tissue; humans; obesity; physiology; white adipose tissue;     Show all 6 Subjects
Abstract:
... The recent re-discovery of brown adipose tissue (BAT) and even more recent discovery of the browning of white adipose tissue (WAT) in humans have generated intense scientific interest in the role of adipose tissue as potential target against obesity and its metabolic complications. The purpose of this review is to: i) critically evaluate the current evidence on the physiological significance of BA ...
DOI:
10.1016/j.bbalip.2018.05.014

3. Insights into the methanogenic degradation of N, N-dimethylformamide: The functional microorganisms and their ecological relationships

Author:
Kong, Zhe; Li, Lu; Wu, Jiang; Zhang, Tao; Li, Yu-You
Source:
Bioresource technology 2019 v.271 pp. 37-47
ISSN:
0960-8524
Subject:
biochemical pathways,   etc   ; activated sludge; anaerobic digestion; bacteria; coculture; hydrolysis; methane; methane production; methanogens; nitrates;     Show all 10 Subjects
Abstract:
... The methanogenic degradation of N, N-dimethylformamide (DMF) was investigated using anaerobic digested sludge (ADS), aerobic activated sludge (AAS) and co-cultured sludge (CCS), respectively. Both the metabolic pathway and the corresponding microorganisms which function in the methanogenic degradation of DMF were elucidated. DMF was unable to be degraded anaerobically by ADS due to the lack of DMF ...
DOI:
10.1016/j.biortech.2018.09.074

4. In memory of Achim Trebst (1929–2017): a pioneer of photosynthesis research

Author:
Bothe, Hermann; Happe, Thomas; Trebst, Simon; Rögner, Matthias
Source:
Photosynthesis research 2018 v.137 no.3 pp. 341-359
ISSN:
0166-8595
Subject:
biochemical pathways,   etc   ; photosystem II; scientists; singlet oxygen;     Show all 4 Subjects
Abstract:
... The life and work of Achim Trebst (1929–2017) was dedicated to photosynthesis, involving a wide span of seminal contributions which cumulated in more than five decades of active research: Major topics include the separation of light and dark phases in photosynthesis, the elucidation of photosynthesis by the use of inhibitors, the identification of the three-dimensional structure of photosystem II ...
DOI:
10.1007/s11120-018-0516-x

5. Hydra Regeneration: Closing the Loop with Mechanical Processes in Morphogenesis

Author:
Braun, Erez; Keren, Kinneret
Source:
BioEssays 2018 v.40 no.7 pp. e1700204
ISSN:
0265-9247
Subject:
biochemical pathways,   etc   ; Hydra; cytoskeleton; morphogenesis; tissues;     Show all 5 Subjects
Abstract:
... The convergence of morphogenesis into viable organisms under variable conditions suggests closed‐loop dynamics involving multiscale functional feedback. We develop the idea that morphogenesis is based on synergy between mechanical and bio‐signaling processes, spanning all levels of organization: molecular, cellular, tissue, up to the whole organism. This synergy provides feedback within and betwee ...
DOI:
10.1002/bies.201700204

6. An In Vivo Perspective of the Role(s) of the Alternative Oxidase Pathway

Author:
Del-Saz, Néstor Fernández; Ribas-Carbo, Miquel; McDonald, Allison E.; Lambers, Hans; Fernie, Alisdair R.; Florez-Sarasa, Igor
Source:
Trends in plant science 2018 v.23 pp. 206-219
ISSN:
1360-1385
Subject:
biochemical pathways,   etc   ; fractionation; in vivo studies; oxidoreductases;     Show all 4 Subjects
Abstract:
... Despite intense research on the in vitro characterization of regulatory factors modulating the alternative oxidase (AOX) pathway, the regulation of its activity in vivo is still not fully understood. Advances concerning in vivo regulation of AOX based on the oxygen-isotope fractionation technique are reviewed, and regulatory factors that merit future research are highlighted. In addition, we revie ...
DOI:
10.1016/j.tplants.2017.11.006

7. Production optimization for concentration and volume-limited fed-batch reactors in biochemical processes

Author:
Liu, Ping; Liu, Xinggao; Zhang, Zeyin; Wang, Yalin; Yang, Chunhua; Gui, Weihua
Source:
Bioprocess and biosystems engineering 2018 v.41 no.3 pp. 407-422
ISSN:
1615-7591
Subject:
biochemical pathways,   etc   ; ethanol; manufacturing; penicillins; product quality;     Show all 5 Subjects
Abstract:
... Since a very slight violation of constraint could cause process safety and product quality problems in biochemical processes, an adaptive approach of fed-batch reactor production optimization that can strictly satisfy constraints over the entire operating time is presented. In this approach, an improved smooth function is proposed such that the inequality constraints can be transformed into smooth ...
DOI:
10.1007/s00449-017-1875-y

8. Correction to: Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate

Author:
Takehara, Ikki; Fujii, Tsubasa; Tanimoto, Yuuki; Kato, Dai-Ichiro; Takeo, Masahiro; Negoro, Seiji
Source:
Applied microbiology and biotechnology 2018 v.102 no.2 pp. 815
ISSN:
0175-7598
Subject:
biochemical pathways,   etc   ; Arthrobacter; bacteria; enzymes; nylon;     Show all 5 Subjects
Abstract:
... The original publication of this paper contains mistakes for Tables 1 and 2 legends as well as the sublabels in Figs. 2, 4, 5, 6, and 7. ...
DOI:
10.1007/s00253-017-8682-x

9. Microbial cell factories for the sustainable manufacturing of B vitamins

Author:
Acevedo-Rocha, Carlos G; Gronenberg, Luisa S; Mack, Matthias; Commichau, Fabian M; Genee, Hans J
Source:
Current opinion in biotechnology 2019 v.56 pp. 18-29
ISSN:
0958-1669
Subject:
biochemical pathways,   etc   ; cosmetics; diet; hazardous waste; humans; manufacturing; markets; metabolic engineering; microorganisms; pharmaceutical industry; sustainable manufacturing; vitamin B complex;     Show all 12 Subjects
Abstract:
... Vitamins are essential compounds in human and animal diets. Their demand is increasing globally in food, feed, cosmetics, chemical and pharmaceutical industries. Most current production methods are unsustainable because they use non-renewable sources and often generate hazardous waste. Many microorganisms produce vitamins naturally, but their corresponding metabolic pathways are tightly regulated ...
DOI:
10.1016/j.copbio.2018.07.006

10. A bioinformatics study on characteristics, metabolic pathways, and cellular functions of the identified S-nitrosylated proteins in postmortem pork muscle

Author:
Liu, Rui; Zhang, Chaoyang; Xing, Lujuan; Zhang, Lili; Zhou, Guanghong; Zhang, Wangang
Source:
Food chemistry 2019 v.274 pp. 407-414
ISSN:
0308-8146
Subject:
biochemical pathways,   etc   ; apoptosis; bioinformatics; cysteine; enzymes; glycolysis; isoelectric point; lysine; meat quality; molecular weight; muscles; myocytes; pork; proteins;     Show all 14 Subjects
Abstract:
... This study aimed to determine the characteristics, metabolic pathways and cellular functions of S-nitrosylated proteins from pork postmortem muscle using bioinformatics analysis. The results showed that S-nitrosylated proteins had a broad range of molecular weight and pI value and were mainly located in the functional region of secondary structure. The motif revealed the lysine (K) positioned at − ...
DOI:
10.1016/j.foodchem.2018.09.038

11. State transitions: a major mortality risk for seasonal species

Author:
Landes, Julie; Perret, Martine; Hardy, Isabelle; Camarda, Carlo Giovanni; Henry, Pierre‐Yves; Pavard, Samuel
Source:
Ecology letters 2017 v.20 no.7 pp. 883-891
ISSN:
1461-023X
Subject:
biochemical pathways,   etc   ; Primates; mortality; risk;     Show all 4 Subjects
Abstract:
... Ageing results from the accumulation of multifactorial damage over time. However, the temporal distribution of this damage remains unknown. In seasonal species, transitions between seasons are critical periods of massive physiological remodelling. We hypothesised that these recurrent peaks of physiological remodelling are costly in terms of survival. We tested whether captive small primates expose ...
DOI:
10.1111/ele.12785

12. Bio-production of gaseous alkenes: ethylene, isoprene, isobutene

Author:
Wilson, James; Gering, Sarah; Pinard, Jessica; Lucas, Ryan; Briggs, Brandon R.
Source:
Biotechnology for biofuels 2018 v.11 no.1 pp. 234
ISSN:
1754-6834
Subject:
biochemical pathways,   etc   ; biological production; emissions; ethylene; isoprene; petrochemicals;     Show all 6 Subjects
Abstract:
... To reduce emissions from petrochemical refinement, bio-production has been heralded as a way to create economically valuable compounds with fewer harmful effects. For example, gaseous alkenes are precursor molecules that can be polymerized into a variety of industrially significant compounds and have biological production pathways. Production levels, however, remain low, thus enhancing bio-product ...
DOI:
10.1186/s13068-018-1230-9

13. Discordance Between Resident and Active Bacterioplankton in Free-Living and Particle-Associated Communities in Estuary Ecosystem

Author:
Li, Jia-Ling; Salam, Nimaichand; Wang, Pan-Deng; Chen, Lin-Xing; Jiao, Jian-Yu; Li, Xin; Xian, Wen-Dong; Han, Ming-Xian; Fang, Bao-Zhu; Mou, Xiao-Zhen; Li, Wen-Jun
Source:
Microbial ecology 2018 v.76 no.3 pp. 637-647
ISSN:
0095-3628
Subject:
biochemical pathways,   etc   ; bacterioplankton; biogeochemical cycles; ecosystems; estuaries; rivers; taxonomy;     Show all 7 Subjects
Abstract:
... Bacterioplankton are the major driving force for biogeochemical cycles in estuarine ecosystems, but the communities that mediate these processes are largely unexplored. We sampled in the Pearl River Estuary (PRE) to examine potential differences in the taxonomic composition of resident (DNA-based) and active (RNA-based) bacterioplankton communities in free-living and particle-associated fractions. ...
DOI:
10.1007/s00248-018-1174-4

14. A pathway for every product? Tools to discover and design plant metabolism

Author:
Jeffryes, James G.; Seaver, Samuel M.D.; Faria, José P.; Henry, Christopher S.
Source:
Plant science 2018 v.273 pp. 61-70
ISSN:
0168-9452
Subject:
biochemical pathways,   etc   ; algorithms; biosynthesis; databases; enzymes; models; synthetic biology;     Show all 7 Subjects
Abstract:
... The vast diversity of plant natural products is a powerful indication of the biosynthetic capacity of plant metabolism. Synthetic biology seeks to capitalize on this ability by understanding and reconfiguring the biosynthetic pathways that generate this diversity to produce novel products with improved efficiency. Here we review the algorithms and databases that presently support the design and ma ...
DOI:
10.1016/j.plantsci.2018.03.025

15. Sniffing bacterial volatile compounds for healthier plants

Author:
Sharifi, Rouhallah; Ryu, Choong-Min
Source:
Current opinion in plant biology 2018 v.44 pp. 88-97
ISSN:
1369-5266
Subject:
biochemical pathways,   etc   ; bacteria; metabolism; nutrients; pathogens; plant physiology; volatile compounds;     Show all 7 Subjects
Abstract:
... Bacterial volatile compounds (BVCs) are not waste or by-products of primary metabolism but rather have critical roles in the biology and ecological competence of bacteria. BVCs are exploited as a source of nutrients and information in plant–bacteria interactions. They target key points in plant physiology, activating downstream metabolic pathways by a domino effect. BVCs are an ancient signal and ...
DOI:
10.1016/j.pbi.2018.03.004

16. Synthesis and production of the antitumor polyketide aurovertins and structurally related compounds

Author:
Li, Wei; Ma, Zihui; Chen, Lin; Yin, Wen-Bing
Source:
Applied microbiology and biotechnology 2018 v.102 no.15 pp. 6373-6381
ISSN:
0175-7598
Subject:
biochemical pathways,   etc   ; antibacterial properties; biosynthesis; engineering; fungi; models; polyketides;     Show all 7 Subjects
Abstract:
... Aurovertins belong to a family of highly reducing polyketides sharing a polyene α-pyrone-type structure. These compounds comprise aurovertin, asteltoxin, avertoxin, citreoviridin, verrucosidin, and their derivatives, which exihibit potent antitumor, antiviral, and antibacterial activities. Until now, over 40 aurovertins and structurally related compounds have been found in the fungal kingdom. Due ...
DOI:
10.1007/s00253-018-9123-1

17. Prospects for engineering dynamic CRISPR–Cas transcriptional circuits to improve bioproduction

Author:
Fontana, Jason; Voje, William E.; Zalatan, Jesse G.; Carothers, James M.
Source:
Journal of industrial microbiology & biotechnology 2018 v.45 no.7 pp. 481-490
ISSN:
1367-5435
Subject:
biochemical pathways,   etc   ; gene regulatory networks; genes; metabolic engineering; synthetic biology;     Show all 5 Subjects
Abstract:
... Dynamic control of gene expression is emerging as an important strategy for controlling flux in metabolic pathways and improving bioproduction of valuable compounds. Integrating dynamic genetic control tools with CRISPR–Cas transcriptional regulation could significantly improve our ability to fine-tune the expression of multiple endogenous and heterologous genes according to the state of the cell. ...
DOI:
10.1007/s10295-018-2039-z

18. Sunlight Brightens Learning and Memory

Author:
Chantranupong, Lynne; Sabatini, Bernardo L.
Source:
Cell 2018 v.173 pp. 1570-1572
ISSN:
0092-8674
Subject:
biochemical pathways,   etc   ; cognition; emotions; memory; mice; solar radiation;     Show all 6 Subjects
Abstract:
... Sunlight can alter mood, behavior, and cognition, but the cellular basis of this phenomenon remains to be fully elucidated. In this issue of Cell, Zhu et al. shed light on a UV-dependent metabolic pathway that leads to increased synaptic release of glutamate and enhanced motor learning and memory in mice. ...
DOI:
10.1016/j.cell.2018.05.044

19. Improvement of industrially important microbial strains by genome shuffling: Current status and future prospects

Author:
Magocha, Tinashe Archbold; Zabed, H.; Yang, Miaomiao; Yun, Junhua; Zhang, Huanhuan; Qi, Xianghui
Source:
Bioresource technology 2018 v.257 pp. 281-289
ISSN:
0960-8524
Subject:
biochemical pathways,   etc   ; DNA shuffling; genome; metabolites; microorganisms; phenotype; protoplast fusion;     Show all 7 Subjects
Abstract:
... The growing demand for biotechnological products against limited metabolic capacity of industrially used microorganisms has led to an increased interest on strain-improvement over the last several decades, which aimed to enhance metabolite yield, substrate uptake and tolerance of the strains. Among a few techniques of strain-improvement, genome shuffling is the most recent and promising approach u ...
DOI:
10.1016/j.biortech.2018.02.118

20. Meroterpenoids from Ganoderma Species: A Review of Last Five Years

Author:
Peng, Xingrong; Qiu, Minghua
Source:
Natural products and bioprospecting 2018 v.8 no.3 pp. 137-149
ISSN:
2192-2195
Subject:
biochemical pathways,   etc   ; Ganoderma; bioactive properties; plant biochemistry; terpenoids;     Show all 5 Subjects
Abstract:
... Meroterpenoids are hybrid natural products that partially originate from the terpenoid pathway. Ganoderma meroterpenoids (GMs) are a type of meroterpenoids containing a 1,2,4-trisubstituted phenyl and a polyunsaturated terpenoid part. Over last 5 years, great efforts have been made to conduct phytochemistry research on the genus Ganoderma, which have led to the isolation and identification of a nu ...
DOI:
10.1007/s13659-018-0164-z