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1. Iridoid glucosides in the genus Sutera (Scrophulariaceae) as chemotaxonomic markers in tribe Limoselleae

Author:
Gousiadou, Chryssoula; Kokubun, Tetsuo; Albach, Dirk C.; Gotfredsen, Charlotte H.; Jensen, Søren Rosendal
Source:
Phytochemistry 2019 v.158 pp. 149-155
ISSN:
0031-9422
Subject:
biochemical pathways,   etc   ; Microdon; Scrophulariaceae; aucubin; chemotaxonomy; glucosides; verbascoside;     Show all 7 Subjects
Abstract:
... From two species of Sutera (S. foetida and S. cordata) (Scrophulariaceae tribe Limoselleae) were isolated three known secoiridoid glucosides (12–14) as well as four iridoid congeners (8–11), all biosynthetically derived from iridodial glucoside (and/or deoxyloganic acid). In addition, two previously unknown compounds were found, namely a terpenoid glucoside lactone (suterolide, 21) and the phenyle ...
DOI:
10.1016/j.phytochem.2018.10.021

2. A sensitive and selective terahertz sensor for the fingerprint detection of lactose

Author:
Han, Baojuan; Han, Zhanghua; Qin, Jianyuan; Wang, Yongmei; Zhao, Zongshan
Source:
Talanta 2019 v.192 pp. 1-5
ISSN:
0039-9140
Subject:
biochemical pathways,   etc   ; electric field; fructose; honors and awards; lactose; transmittance;     Show all 6 Subjects
Abstract:
... Special recognition to molecules is essential for many biochemical processes, thus highly sensitive sensing methods for molecule recognition are strongly demanded. Recently, metamaterials present a unique platform for sensing applications owing to their exotic properties. In the current work, a metamaterial sensor for enhanced fingerprint detection of lactose based on resonant coupling of plasmoni ...
DOI:
10.1016/j.talanta.2018.09.029

3. Efficient glycosylation with glycosyl ortho-allylbenzoates as donors

Author:
Liang, Haijing; Ma, Lixia; Li, Changwei; Peng, Qiang; Wang, Zhaoyan; Zhang, Zhan-xin; Yu, Lan; Liu, Huanxiang; An, Fengli; Xue, Weihua
Source:
Tetrahedron letters 2019 v.60 no.1 pp. 84-87
ISSN:
0040-4039
Subject:
biochemical pathways,   etc   ; chemical structure; glycosides; glycosylation; models; organic compounds;     Show all 6 Subjects
Abstract:
... Glycosylation reactions are significant as they provide access to model compounds that are useful for elucidating biochemical pathways. Herein, we describe the development of glycosyl ortho-alkynylbenzoates as novel, bench-top stable, and readily available glycosyl donors. Glycosylation is promoted by inexpensive trimethylsilyl triflate (TMSOTf) in combination with N-iodosuccinimide (NIS) under mi ...
DOI:
10.1016/j.tetlet.2018.11.061

4. Nutrients, immune system, and exercise: Where will it take us?

Author:
Batatinha, Helena A.P.; Biondo, Luana A.; Lira, Fabio S.; Castell, Linda M.; Rosa-Neto, José C.
Source:
Nutrition 2019 v.61 pp. 151-156
ISSN:
0899-9007
Subject:
biochemical pathways,   etc   ; energy; exercise; glucose; glutamine; homeostasis; immune system; metabolism; nutrient availability; nutrients;     Show all 10 Subjects
Abstract:
... The immune system plays a key role in controlling infections, repairing injuries, and restoring homeostasis. Immune cells are bioenergetically expensive during activation, which requires a tightly regulated control of the metabolic pathways, which is mostly regulated by two cellular energy sensors: Adenosine monophosphate–activated protein kinase and mammalian target of rapamycin. The activation a ...
DOI:
10.1016/j.nut.2018.09.019

5. Bromocatechol conjugates from a Chinese marine red alga, Symphyocladia latiuscula

Author:
Xu, Xiuli; Yang, Haijin; Khalil, Zeinab G.; Yin, Liyuan; Xiao, Xue; Salim, Angela A.; Song, Fuhang; Capon, Robert J.
Source:
Phytochemistry 2019 v.158 pp. 20-25
ISSN:
0031-9422
Subject:
biochemical pathways,   etc   ; Rhodophyta; aconitic acid; coastal water; solvolysis; spectral analysis; China;     Show all 7 Subjects
Abstract:
... This study describes an investigation into polybromocatechol conjugates isolated from a marine red alga, Symphyocladia latiuscula (Harvey) Yamada, collected from coastal waters off Qingdao, China. We report on the isolation and characterisation of eight undescribed aconitic acid conjugates, symphyocladins R-X, including a likely solvolysis artifact of symphyocladin S, and an undescribed furanoyl c ...
DOI:
10.1016/j.phytochem.2018.10.026

6. Something ancient and something neofunctionalized—evolution of land plant hormone signaling pathways

Author:
Bowman, John L; Briginshaw, Liam N; Fisher, Tom J; Flores-Sandoval, Eduardo
Source:
Current opinion in plant biology 2019 v.47 pp. 64-72
ISSN:
1369-5266
Subject:
biochemical pathways,   etc   ; Angiospermae; algae; ancestry; embryophytes; evolution; ligands; plant hormones; signal transduction; transcription (genetics); uncertainty;     Show all 11 Subjects
Abstract:
... The evolution of land plants from a charophycean algal ancestor was accompanied by an increased diversity of regulatory networks, including signaling pathways mediating cellular communication within plants and between plants and the environment. Canonical land plant hormone signaling pathways were originally identified in angiosperms, and comparative studies in basal taxa show that they have been ...
DOI:
10.1016/j.pbi.2018.09.009

7. Degradation and defluorination of 6:2 fluorotelomer sulfonamidoalkyl betaine and 6:2 fluorotelomer sulfonate by Gordonia sp. strain NB4-1Y under sulfur-limiting conditions

Author:
Shaw, Dayton M.J.; Munoz, Gabriel; Bottos, Eric M.; Duy, Sung Vo; Sauvé, Sébastien; Liu, Jinxia; Van Hamme, Jonathan D.
Source:
The Science of the total environment 2019 v.647 pp. 690-698
ISSN:
0048-9697
Subject:
biochemical pathways,   etc   ; aquatic ecosystems; betaine; biodegradation; fire fighting; foams; metabolism; water solubility;     Show all 8 Subjects
Abstract:
... 6:2 fluorotelomer sulfonamidoalkyl betaine (6:2 FTAB) is a major component of aqueous film-forming foams (AFFFs) used for firefighting and is frequently detected, along with one of its suspected transformation products, 6:2 fluorotelomer sulfonate (6:2 FTSA), in terrestrial and aquatic ecosystems impacted by AFFF usage. Biochemical processes underlying bacterial biodegradation of these compounds r ...
DOI:
10.1016/j.scitotenv.2018.08.012

8. Brown and beige fat: From molecules to physiology Molecular and cell biology of lipids

Author:
Chondronikola, Maria; Sidossis, Labros S.
Source:
Biochimica et biophysica acta 2019 v.1864 no.1 pp. 91-103
ISSN:
1388-1981
Subject:
biochemical pathways,   etc   ; brown adipose tissue; humans; obesity; physiology; white adipose tissue;     Show all 6 Subjects
Abstract:
... The recent re-discovery of brown adipose tissue (BAT) and even more recent discovery of the browning of white adipose tissue (WAT) in humans have generated intense scientific interest in the role of adipose tissue as potential target against obesity and its metabolic complications. The purpose of this review is to: i) critically evaluate the current evidence on the physiological significance of BA ...
DOI:
10.1016/j.bbalip.2018.05.014

9. Development, activation, and therapeutic potential of thermogenic adipocytes

Author:
Emont, Margo P.; Kim, Dong-il; Wu, Jun
Source:
Biochimica et biophysica acta 2019 v.1864 no.1 pp. 13-19
ISSN:
1388-1981
Subject:
biochemical pathways,   etc   ; adipocytes; cell lines; energy; heat; humans; metabolism; therapeutics; transcription (genetics);     Show all 9 Subjects
Abstract:
... During the last decade, significant progress has been made in understanding adipocytes with a particular focus on thermogenic fat cells, which effectively convert chemical energy into heat in addition to their other metabolic functions. It has been increasingly recognized that different types and subtypes of adipocytes exist and the developmental origins of various types of fat cells are being int ...
DOI:
10.1016/j.bbalip.2018.05.004

10. Insights into the methanogenic degradation of N, N-dimethylformamide: The functional microorganisms and their ecological relationships

Author:
Kong, Zhe; Li, Lu; Wu, Jiang; Zhang, Tao; Li, Yu-You
Source:
Bioresource technology 2019 v.271 pp. 37-47
ISSN:
0960-8524
Subject:
biochemical pathways,   etc   ; activated sludge; anaerobic digestion; bacteria; coculture; hydrolysis; methane; methane production; methanogens; nitrates;     Show all 10 Subjects
Abstract:
... The methanogenic degradation of N, N-dimethylformamide (DMF) was investigated using anaerobic digested sludge (ADS), aerobic activated sludge (AAS) and co-cultured sludge (CCS), respectively. Both the metabolic pathway and the corresponding microorganisms which function in the methanogenic degradation of DMF were elucidated. DMF was unable to be degraded anaerobically by ADS due to the lack of DMF ...
DOI:
10.1016/j.biortech.2018.09.074

11. Process analytical technologies to monitor the liquid phase of anaerobic cultures

Author:
Bockisch, Anika; Kielhorn, Erich; Neubauer, Peter; Junne, Stefan
Source:
Process biochemistry 2019 v.76 pp. 1-10
ISSN:
1359-5113
Subject:
biochemical pathways,   etc   ; acoustics; beverages; electrochemistry; fermentation; liquids; pharmaceutical industry; process monitoring; spectroscopy; viability;     Show all 10 Subjects
Abstract:
... Recent advances in sensor development and miniaturization offer new possibilities to monitor and control bioprocesses. Specific requirements for anaerobic processes in terms of low costs and high robustness against insoluble fractions and impurities in media led to a decelerated penetration of new technology in this field. Since no regulatory framework demands for process monitoring and documentat ...
DOI:
10.1016/j.procbio.2018.10.005

12. Designing artificial metabolic pathways, construction of target enzymes, and analysis of their function

Author:
Mori, Yutaro; Shirai, Tomokazu
Source:
Current opinion in biotechnology 2018 v.54 pp. 41-44
ISSN:
0958-1669
Subject:
biochemical pathways,   etc   ; enzymatic reactions; enzymes; genes; microorganisms;     Show all 5 Subjects
Abstract:
... Artificial design of metabolic pathways is essential for the production of useful compounds using microbes. Based on this design, heterogeneous genes are introduced into the host, and then various analysis and evaluation methods are conducted to ensure that the target enzyme reactions are functionalized within the cell. In this chapter, we list successful examples of useful compounds produced by d ...
DOI:
10.1016/j.copbio.2018.01.021

13. Biosynthesis of Plant Triterpenoid Saponins in Microbial Cell Factories

Author:
Zhao, Yu-jia; Li, Chun
Source:
Journal of agricultural and food chemistry 2018 v.66 no.46 pp. 12155-12165
ISSN:
1520-5118
Subject:
biochemical pathways,   etc   ; biosynthesis; food industry; triterpenoid saponins;     Show all 4 Subjects
Abstract:
... Triterpenoid saponins are triterpenoid glycoside compounds which have been widely used in pharmaceutical, agricultural, and food industries. Traditionally, they are extracted from plants, which is time-consuming and environmentally unfriendly. Recently, de novo synthesis of triterpenoid saponins in microbial cell factories was realized, which provides a promising and green approach to alter the tr ...
DOI:
10.1021/acs.jafc.8b04657

14. Organization out of disorder: liquid–liquid phase separation in plants

Author:
Cuevas-Velazquez, Cesar L; Dinneny, José R
Source:
Current opinion in plant biology 2018 v.45 pp. 68-74
ISSN:
1369-5266
Subject:
biochemical pathways,   etc   ; RNA; eukaryotic cells; proteins; separation;     Show all 5 Subjects
Abstract:
... Membraneless compartments are formed from the dynamic physical association of proteins and RNAs through liquid–liquid phase separation, and have recently emerged as an exciting new mechanism to explain the dynamic organization of biochemical processes in the cell. In this review, we provide an overview of the current knowledge of the process of phase separation in plants and other eukaryotes. We d ...
DOI:
10.1016/j.pbi.2018.05.005

15. In memory of Achim Trebst (1929–2017): a pioneer of photosynthesis research

Author:
Bothe, Hermann; Happe, Thomas; Trebst, Simon; Rögner, Matthias
Source:
Photosynthesis research 2018 v.137 no.3 pp. 341-359
ISSN:
0166-8595
Subject:
biochemical pathways,   etc   ; photosystem II; scientists; singlet oxygen;     Show all 4 Subjects
Abstract:
... The life and work of Achim Trebst (1929–2017) was dedicated to photosynthesis, involving a wide span of seminal contributions which cumulated in more than five decades of active research: Major topics include the separation of light and dark phases in photosynthesis, the elucidation of photosynthesis by the use of inhibitors, the identification of the three-dimensional structure of photosystem II ...
DOI:
10.1007/s11120-018-0516-x

16. Hydra Regeneration: Closing the Loop with Mechanical Processes in Morphogenesis

Author:
Braun, Erez; Keren, Kinneret
Source:
BioEssays 2018 v.40 no.7 pp. e1700204
ISSN:
0265-9247
Subject:
biochemical pathways,   etc   ; Hydra; cytoskeleton; morphogenesis; tissues;     Show all 5 Subjects
Abstract:
... The convergence of morphogenesis into viable organisms under variable conditions suggests closed‐loop dynamics involving multiscale functional feedback. We develop the idea that morphogenesis is based on synergy between mechanical and bio‐signaling processes, spanning all levels of organization: molecular, cellular, tissue, up to the whole organism. This synergy provides feedback within and betwee ...
DOI:
10.1002/bies.201700204

17. An In Vivo Perspective of the Role(s) of the Alternative Oxidase Pathway

Author:
Del-Saz, Néstor Fernández; Ribas-Carbo, Miquel; McDonald, Allison E.; Lambers, Hans; Fernie, Alisdair R.; Florez-Sarasa, Igor
Source:
Trends in plant science 2018 v.23 pp. 206-219
ISSN:
1360-1385
Subject:
biochemical pathways,   etc   ; fractionation; in vivo studies; oxidoreductases;     Show all 4 Subjects
Abstract:
... Despite intense research on the in vitro characterization of regulatory factors modulating the alternative oxidase (AOX) pathway, the regulation of its activity in vivo is still not fully understood. Advances concerning in vivo regulation of AOX based on the oxygen-isotope fractionation technique are reviewed, and regulatory factors that merit future research are highlighted. In addition, we revie ...
DOI:
10.1016/j.tplants.2017.11.006

18. Production optimization for concentration and volume-limited fed-batch reactors in biochemical processes

Author:
Liu, Ping; Liu, Xinggao; Zhang, Zeyin; Wang, Yalin; Yang, Chunhua; Gui, Weihua
Source:
Bioprocess and biosystems engineering 2018 v.41 no.3 pp. 407-422
ISSN:
1615-7591
Subject:
biochemical pathways,   etc   ; ethanol; manufacturing; penicillins; product quality;     Show all 5 Subjects
Abstract:
... Since a very slight violation of constraint could cause process safety and product quality problems in biochemical processes, an adaptive approach of fed-batch reactor production optimization that can strictly satisfy constraints over the entire operating time is presented. In this approach, an improved smooth function is proposed such that the inequality constraints can be transformed into smooth ...
DOI:
10.1007/s00449-017-1875-y

19. Correction to: Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate

Author:
Takehara, Ikki; Fujii, Tsubasa; Tanimoto, Yuuki; Kato, Dai-Ichiro; Takeo, Masahiro; Negoro, Seiji
Source:
Applied microbiology and biotechnology 2018 v.102 no.2 pp. 815
ISSN:
0175-7598
Subject:
biochemical pathways,   etc   ; Arthrobacter; bacteria; enzymes; nylon;     Show all 5 Subjects
Abstract:
... The original publication of this paper contains mistakes for Tables 1 and 2 legends as well as the sublabels in Figs. 2, 4, 5, 6, and 7. ...
DOI:
10.1007/s00253-017-8682-x

20. Microbial cell factories for the sustainable manufacturing of B vitamins

Author:
Acevedo-Rocha, Carlos G; Gronenberg, Luisa S; Mack, Matthias; Commichau, Fabian M; Genee, Hans J
Source:
Current opinion in biotechnology 2019 v.56 pp. 18-29
ISSN:
0958-1669
Subject:
biochemical pathways,   etc   ; cosmetics; diet; hazardous waste; humans; manufacturing; markets; metabolic engineering; microorganisms; pharmaceutical industry; sustainable manufacturing; vitamin B complex;     Show all 12 Subjects
Abstract:
... Vitamins are essential compounds in human and animal diets. Their demand is increasing globally in food, feed, cosmetics, chemical and pharmaceutical industries. Most current production methods are unsustainable because they use non-renewable sources and often generate hazardous waste. Many microorganisms produce vitamins naturally, but their corresponding metabolic pathways are tightly regulated ...
DOI:
10.1016/j.copbio.2018.07.006