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1. Shotgun lipidomics-based characterization of the landscape of lipid metabolism in colorectal cancer

Author:
Wang, Yuting; Hinz, Sebastian; Uckermann, Ortrud; Hönscheid, Pia; von Schönfels, Witigo; Burmeister, Greta; Hendricks, Alexander; Ackerman, Jacobo Miranda; Baretton, Gustavo B.; Hampe, Jochen; Brosch, Mario; Schafmayer, Clemens; Shevchenko, Andrej; Zeissig, Sebastian
Source:
Biochimica et biophysica acta 2020 v.1865 no.3 pp. 158579
ISSN:
1388-1981
Subject:
blood lipids,   etc   ; biopsy; colorectal neoplasms; gene expression; lipid composition; lipid metabolism; mucosa; phospholipids; reactive oxygen species;     Show all 9 Subjects
Abstract:
... Solid tumors are characterized by global metabolic alterations which contribute to their growth and progression. Altered gene expression profiles and plasma lipid composition suggested a role for metabolic reprogramming in colorectal cancer (CRC) development. However, a conclusive picture of CRC-associated lipidome alterations in the tumor tissue has not emerged. Here, we determined molar abundanc ...
DOI:
10.1016/j.bbalip.2019.158579

2. Xylan-oligosaccharides ameliorate high fat diet induced obesity and glucose intolerance and modulate plasma lipid profile and gut microbiota in mice

Author:
Zhang, Chengnan; Abdulaziz Abbod Abdo, Abdullah; Kaddour, Benariba; Wu, Qiuhua; Xin, Liang; Li, Xiuting; Fan, Guangsen; Teng, Chao
Source:
Journal of functional foods 2020 v.64 pp. 103622
ISSN:
1756-4646
Subject:
blood lipids,   etc   ; Bifidobacterium; Roseburia; ceramides; diacylglycerols; glucose; high fat diet; intestinal microorganisms; lipid composition; mice; obesity;     Show all 11 Subjects
Abstract:
... In recent years, xylan-oligosaccharides (XOS) have attracted much interest as an alternative sweetener for formulating an anti-obesity diet. The present study combining the plasma metabolic profile and gut microbiota analyses investigated the anti-obesity activity of XOS and the possible mechanism in mice. Our results showed that the dietary supplementations with 5% and 10% XOS could significantly ...
DOI:
10.1016/j.jff.2019.103622

3. Association between serum hepatocyte growth factor and prognosis of ischemic stroke: The role of blood lipid status

Author:
Zhu, Zhengbao; Wang, Aili; Guo, Daoxia; Bu, Xiaoqing; Xu, Tan; Zhong, Chongke; Peng, Yanbo; Xu, Tian; Peng, Hao; Chen, Jing; Ju, Zhong; Geng, Deqin; He, Jiang; Zhang, Yonghong
Source:
Nutrition, metabolism, and cardiovascular diseases 2020 v.30 no.3 pp. 492-499
ISSN:
0939-4753
Subject:
blood lipids,   etc   ; blood serum; death; hepatocyte growth factor; hyperlipidemia; lipids; odds ratio; patients; prediction; prognosis; risk factors; stroke; China;     Show all 13 Subjects
Abstract:
... High serum hepatocyte growth factor (HGF) levels increase the risk of ischemic stroke and are probably associated with outcomes after ischemic stroke. However, it remains unclear whether the association between HGF and ischemic stroke prognosis is modified by blood lipid status.Data were derived from the CATIS (China Antihypertensive Trial in Acute Ischemic Stroke), and we measured baseline serum ...
DOI:
10.1016/j.numecd.2019.11.005

4. Nattospes as Effective and Safe Functional Supplements in Management of Stroke

Author:
Pham, Phuong T.; Han, Bo; Hoang, Ba X.
Source:
Journal of medicinal food 2020
ISSN:
1557-7600
Subject:
blood lipids,   etc   ; adjuvants; adverse effects; blood pressure; dietary supplements; electroacupuncture; humans; ingestion; patients; quality of life; randomized clinical trials; stroke;     Show all 12 Subjects
Abstract:
... Stroke remains a major cause of human disability worldwide. Interventions and rehabilitation at the poststroke stage are critical for recovery. A single-blinded randomized controlled trial was conducted on 61 patients diagnosed with subacute stage of ischemic stroke. Ingestion of Nattospecs was tested as an adjuvant to support rehabilitation when combined with standard of care (SOC) treatment (ele ...
DOI:
10.1089/jmf.2019.0183

5. Order restricted univariate and multivariate inference with adjustment for covariates in partially linear models

Author:
Bogomolov, Marina; Davidov, Ori
Source:
Computational statistics & data analysis 2019 v.133 pp. 20-27
ISSN:
0167-9473
Subject:
blood lipids,   etc   ; linear models; methodology; pollutants; pregnant women;     Show all 5 Subjects
Abstract:
... In a variety of applications researchers are interested in comparing two or more naturally ordered experimental conditions after adjusting for covariates. Addressing this problem we develop a methodology for estimating a mean response conditional on covariates in the framework of partially linear models which allows the effects of some covariates to be modeled nonparametrically. Our focus is on un ...
DOI:
10.1016/j.csda.2018.08.019

6. The physiological functions and pharmaceutical applications of inulin: A review

Author:
Wan, Xinhuan; Guo, Hao; Liang, Yiyu; Zhou, Changzheng; Liu, Zihao; Li, Kunwei; Niu, Fengju; Zhai, Xin; Wang, Lizhu
Source:
Carbohydrate polymers 2020 v.246 pp. 116589
ISSN:
0144-8617
Subject:
blood lipids,   etc   ; Jerusalem artichokes; antioxidants; bioactive properties; blood glucose; chicory; constipation; diabetes; drug carriers; fat replacers; food industry; intestinal microorganisms; inulin; pharmaceutical industry; prebiotics; stabilizers; thickeners;     Show all 17 Subjects
Abstract:
... Inulin (IN), a fructan-type plant polysaccharide, is widely found in nature. The major plant sources of IN include chicory, Jerusalem artichoke, dahlia etc. Studies have found that IN possessed a wide array of biological activities, e.g. as a prebiotic to improve the intestinal microbe environment, regulating blood sugar, regulating blood lipids, antioxidant, anticancer, immune regulation and so o ...
DOI:
10.1016/j.carbpol.2020.116589

7. Influence of fermentation on antioxidant and hypolipidemic properties of maifanite mineral water-cultured common buckwheat sprouts

Author:
Chen, Tiejun; Piao, Meizi; Ehsanur Rahman, Syed Md.; Zhang, Lehong; Deng, Yang
Source:
Food chemistry 2020 v.321 pp. 126741
ISSN:
0308-8146
Subject:
blood lipids,   etc   ; 2,2-diphenyl-1-picrylhydrazyl; Lactobacillus plantarum; Saccharomyces cerevisiae; antioxidant activity; buckwheat sprouts; dose response; fermentation; foods; hydroxyl radicals; liver; mice; mineral water; rutin;     Show all 14 Subjects
Abstract:
... Buckwheat sprouts (BS) becomes popular due to its’ health-promoting properties as food product. The effects of fermentation with Saccharomyces cerevisiae and Lactobacillus plantarum on antioxidant and hypolipidemic activities as well as functional composition in common BS cultivated in maifanite mineral water were investigated here. DPPH and ·OH results showed higher antioxidant potential in ferme ...
DOI:
10.1016/j.foodchem.2020.126741

8. Effects of soy isoflavones on serum lipids and lipoprotein (a) in peritoneal dialysis patients

Author:
Yari, Zahra; Tabibi, Hadi; Najafi, Iraj; Hedayati, Mehdi; Movahedian, Mina
Source:
Nutrition, metabolism, and cardiovascular diseases 2020 v.30 no.8 pp. 1382-1388
ISSN:
0939-4753
Subject:
blood lipids,   etc   ; blood serum; cardiovascular diseases; dialysis; high density lipoprotein cholesterol; isoflavones; low density lipoprotein cholesterol; metabolism; patients; placebos; randomized clinical trials; triacylglycerols;     Show all 12 Subjects
Abstract:
... Lipid abnormalities are common in peritoneal dialysis (PD) patients and no effective treatment to decrease serum lipoprotein (a) [Lp(a)] in dialysis patients is known so far. Therefore, this research was designed to investigate the effects of soy isoflavone supplement on serum lipids and Lp(a) in PD patients.In this randomized, double-blind, placebo-controlled trial, 40 PD patients were randomly a ...
DOI:
10.1016/j.numecd.2020.04.023

9. Effect of time-restricted feeding on metabolic risk and circadian rhythm associated with gut microbiome in healthy males

Author:
Zeb, Falak; Wu, Xiaoyue; Chen, Lijun; Fatima, Sadia; Haq, Ijaz-ul; Chen, Aochang; Majeed, Fatima; Feng, Qing; Li, Min
Source:
The British journal of nutrition 2020 v.123 no.11 pp. 1216-1226
ISSN:
1475-2662
Subject:
blood lipids,   etc   ; adults; bacteria; blood; circadian rhythm; gene expression; genes; hyperlipidemia; intestinal microorganisms; liver; males; obesity; quantitative polymerase chain reaction; ribosomal RNA; risk; sequence analysis;     Show all 16 Subjects
Abstract:
... Time-restricted feeding (TRF) confers protection against nutritional challenges that predispose obesity and metabolic risks through involvement of circadian locomotor output cycles protein kaput genes and gut microbiome, but the underlying mechanism is not clearly understood. Therefore, the present study examined the effects of TRF on metabolic markers and circadian rhythm associated with gut micr ...
DOI:
10.1017/S0007114519003428

10. Short-term exposure to air pollution and its interaction effects with two ABO SNPs on blood lipid levels in northern China: A family-based study

Author:
Wu, Yao; Tian, Yaohua; Wang, Mengying; Wang, Xiaowen; Wu, Junhui; Wang, Zijing; Hu, Yonghua
Source:
Chemosphere 2020 v.249 pp. 126120
ISSN:
0045-6535
Subject:
blood lipids,   etc   ; acute exposure; aerodynamics; air pollution; alleles; at-risk population; genetic background; high density lipoprotein cholesterol; low density lipoprotein cholesterol; models; particulates; single nucleotide polymorphism; triacylglycerols; China;     Show all 14 Subjects
Abstract:
... We examined the main effects of ambient particulate matters, as well as whether single-nucleotide polymorphisms (SNPs), located within ABO gene would modify the relationship. Data were collected from a family-based study conducted in Northern China. A generalized additive model with a Gaussian link and with each family as a stratum was applied to estimate the percentage change in blood lipid level ...
DOI:
10.1016/j.chemosphere.2020.126120

11. Vitamin D-related genes and cardiometabolic markers in healthy children: a Mendelian randomisation study

Author:
Lopez-Mayorga, Ania; Hauger, Hanne; Petersen, Rikke A.; Vogel, Ulla; Damsgaard, Camilla T.; Lauritzen, Lotte
Source:
The British journal of nutrition 2020 v.123 no.10 pp. 1138-1147
ISSN:
1475-2662
Subject:
blood lipids,   etc   ; alleles; blood serum; children; complement; cytochrome P-450; genetic variation; genotyping; homozygosity; insulin; metabolism; observational studies; risk factors; single nucleotide polymorphism; systolic blood pressure; vitamin D;     Show all 16 Subjects
Abstract:
... Observational studies show associations between low serum 25-hydroxyvitamin D (25(OH)D) and cardiometabolic risk markers. This Mendelian randomisation study examined associations between cardiometabolic markers in children and SNP in genes related to vitamin D metabolism (DHCR7; group-specific complement (GC); cytochrome P450 subfamily IIR1 (CYP2R1); and CYP24A1) and action (CYP27B1 and VDR). In 6 ...
DOI:
10.1017/S0007114520000148

12. The utility of anthopometric indicators to identify cardiovascular risk factors in Vietnamese children

Author:
Mai, T. M. T.; Gallegos, D.; Jones, L.; Tran, Q. C.; Tran, T. M. H.; van der Pols, J. C.
Source:
The British journal of nutrition 2020 v.123 no.9 pp. 1043-1055
ISSN:
1475-2662
Subject:
blood lipids,   etc   ; Vietnamese people; adolescents; adolescents at risk; blood pressure; body mass index; hyperlipidemia; risk factors; school children; surveys; waist circumference; waist-to-height ratio; Asia;     Show all 13 Subjects
Abstract:
... BMI, waist circumference (WC) and waist-to-height ratio (WHtR) can be used for discriminating children and adolescents at risk of CVD. However, consensus on how to use these anthropometric indicators is lacking for children and adolescents in Asia. Discrete criteria are promoted internationally, but continuous variables could be used. Data from a survey of 10 949 Vietnamese school-aged children (6 ...
DOI:
10.1017/S0007114520000203

13. Serum concentrations of persistent organic pollutants and the metabolic syndrome in Akwesasne Mohawks, a Native American community

Author:
Aminov, Zafar; Carpenter, David O.
Source:
Environmental pollution 2020 v.260 pp. 114004
ISSN:
0269-7491
Subject:
blood lipids,   etc   ; American Indians; DDE (pesticide); blood sampling; blood serum; diabetes; fasting; glucose; hexachlorobenzene; hyperlipidemia; hypertension; metabolic syndrome; mirex; obesity; persistent organic pollutants; polychlorinated biphenyls; questionnaires; risk factors;     Show all 18 Subjects
Abstract:
... The metabolic syndrome (MetS) is a group of diseases that tend to occur together, including diabetes, hypertension, central obesity, cardiovascular disease and hyperlipidemia. Exposure to persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) has been associated with increased risk of development of several of the components of the MetS. ...
DOI:
10.1016/j.envpol.2020.114004

14. Adherence to a priori dietary indexes and baseline prevalence of cardiovascular risk factors in the PREDIMED-Plus randomised trial

Author:
Alvarez-Alvarez, Ismael; Toledo, Estefanía; Lecea, Oscar; Salas-Salvadó, Jordi; Corella, Dolores; Buil-Cosiales, Pilar; Zomeño, María Dolores; Vioque, Jesús; Martinez, J. Alfredo; Konieczna, Jadwiga; Barón-López, Francisco J.; López-Miranda, José; Estruch, Ramon; Bueno-Cavanillas, Aurora; Alonso-Gómez, Ángel M.; Tur, Josep A.; Tinahones, Francisco J.; Serra-Majem, Lluís; Martín, Vicente; Ortega-Calvo, Manuel; Vázquez, Clotilde; Pintó, Xavier; Vidal, Josep; Daimiel, Lidia; Delgado-Rodríguez, Miguel; Matía, Pilar; González, José I.; Díaz-López, Andrés; Paz-Graniel, Indira; Muñoz, Miguel A.; Fito, Montse; Pertusa-Martinez, Salvador; Abete, Itziar; García-Ríos, Antonio; Ros, Emilio; Ruiz-Canela, Miguel; Martínez-González, Miguel Á.
Source:
European journal of nutrition 2020 v.59 no.3 pp. 1219-1232
ISSN:
1436-6207
Subject:
blood lipids,   etc   ; Mediterranean diet; death; diabetes; elderly; healthy eating habits; hyperlipidemia; hypertension; lipid composition; men; metabolic syndrome; multivariate analysis; nutritional adequacy; obesity; risk factors; women;     Show all 16 Subjects
Abstract:
... PURPOSE: Cardiovascular disease remains the global leading cause of death. We evaluated at baseline the association between the adherence to eight a priori high-quality dietary scores and the prevalence of individual and clustered cardiovascular risk factors (CVRF) in the PREDIMED-Plus cohort. METHODS: All PREDIMED-Plus participants (6874 men and women aged 55–75 years, with overweight/obesity and ...
DOI:
10.1007/s00394-019-01982-x

15. A 10‐year longitudinal study on the associations between changes in plant‐based diet indices, anthropometric parameters and blood lipids in a Flemish adult population

Author:
Waterplas, Jana; Versele, Vickà; D'Hondt, Eva; Lefevre, Johan; Mertens, Evelien; Charlier, Ruben; Knaeps, Sara; Clarys, Peter
Source:
Nutrition & dietetics 2020 v.77 no.2 pp. 196-203
ISSN:
1446-6368
Subject:
blood lipids,   etc   ; adults; animal-based foods; body mass index; environmental sustainability; longitudinal studies; men; models; plant-based diet; plant-based foods; regression analysis; women;     Show all 12 Subjects
Abstract:
... AIM: Plant‐based diets are recommended in the context of environmental sustainability and health. Since not all plant foods can be considered beneficial, a distinction needs to be made between healthful and unhealthful plant foods. The aim of this study was to investigate longitudinal associations between changes in an overall plant‐based diet index, a healthful plant‐based diet index and an unhea ...
DOI:
10.1111/1747-0080.12578

16. Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study

Author:
Hovland, Ida Heir; Leikanger, Ingrid Sande; Stokkeland, Oddbjørg; Waage, Kaia Hevrøy; Mjøs, Svein A.; Brokstad, Karl A.; McCann, Adrian; Ueland, Per Magne; Slizyte, Rasa; Carvajal, Ana; Mellgren, Gunnar; Remman, Tore; Høgøy, Ingmar; Gudbrandsen, Oddrun A.
Source:
European journal of nutrition 2020 v.59 no.3 pp. 1013-1029
ISSN:
1436-6207
Subject:
blood lipids,   etc   ; 3-hydroxybutyric acid; acetoacetic acid; adults; blood serum; c-peptide; glucose; herring; insulin resistance; lipid content; milk; milk proteins; overweight; salmon;     Show all 14 Subjects
Abstract:
... PURPOSE: To examine whether supplementation with low doses of fish or milk proteins would affect glucose regulation and circulating lipid concentrations in overweight healthy adults. METHODS: Ninety-three overweight adults were assigned to receive 2.5 g protein/day from herring (HER), salmon (SAL), cod (COD) or milk (CAS, a casein–whey mixture as positive control) as tablets for 8 weeks. RESULTS: ...
DOI:
10.1007/s00394-019-01963-0

17. In vivo anti-obesity effects of Monascus pigment threonine derivative with enhanced hydrophilicity

Author:
Choe, Deokyeong; Jang, Heeyoung; Jung, Hyun Ho; Shin, Chul Soo; Johnston, Tony V.; Kim, Daehwan; Ku, Seockmo
Source:
Journal of functional foods 2020 v.67 pp. 103849
ISSN:
1756-4646
Subject:
blood lipids,   etc   ; Monascus; abdominal fat; amines; body weight changes; diet; epididymis; hydrophilicity; hydrophobicity; in vivo studies; kidneys; liver; mice; spleen; threonine; toxicity; tryptophan;     Show all 17 Subjects
Abstract:
... The hydrophobicity and anti-obesity characteristics of the threonine (Thr) derivative of Monascus pigment were determined and compared with 2-(p-tolyl)-ethylamine (TEA) and tryptophan (Trp) derivatives of the same. Treatment by all three derivatives decreased body weight gain, epididymal fat weight, and abdominal fat in mice. The lowest body weight gain and epididymal fat weight were observed with ...
DOI:
10.1016/j.jff.2020.103849

18. Associations of a mixture of urinary phthalate metabolites with blood lipid traits: A repeated-measures pilot study

Author:
Zhu, Qingqing; Hou, Jian; Yin, Wenjun; Ye, Fang; Xu, Tian; Cheng, Juan; Yu, Zhiqiang; Wang, Lin; Yuan, Jing
Source:
Environmental pollution 2020 v.257 pp. 113509
ISSN:
0269-7491
Subject:
blood lipids,   etc   ; Bayesian theory; clinical examination; high performance liquid chromatography; lipid metabolism; low density lipoprotein cholesterol; metabolites; models; phthalates; questionnaires; summer; surveys; tandem mass spectrometry; urine; winter; China;     Show all 16 Subjects
Abstract:
... Evidence is available about the associations of phthalates or their metabolites with blood lipids, however, the mixture effects of multiple phthalate metabolites on blood lipid traits remain largely unknown. In this pilot study, 106 individuals at three age groups of <18, 18- and ≥60 years were recruited from the residents (n = 1240) who were randomly selected from two communities in Wuhan city, C ...
DOI:
10.1016/j.envpol.2019.113509

19. The impact of probiotic yogurt consumption on lipid profiles in subjects with mild to moderate hypercholesterolemia: A systematic review and meta-analysis of randomized controlled trials

Author:
Pourrajab, Behnaz; Fatahi, Somaye; Dehnad, Afsaneh; Kord Varkaneh, Hamed; Shidfar, Farzad
Source:
Nutrition, metabolism, and cardiovascular diseases 2020 v.30 no.1 pp. 11-22
ISSN:
0939-4753
Subject:
blood lipids,   etc   ; confidence interval; databases; high density lipoprotein cholesterol; hypercholesterolemia; lipid composition; low density lipoprotein cholesterol; meta-analysis; probiotics; randomized clinical trials; systematic review; triacylglycerols; yogurt;     Show all 13 Subjects
Abstract:
... Potential beneficial effect of probiotic yogurt on the lipid profile has raised much interest. However, the results are inconsistent in this regard. The aim of the study is to determine the effects of probiotic yogurt on serum lipid profile in individuals with mild to moderate hypercholesterolemia.Online databases including PubMed, Scopus, ISI Web of Science, Cochrane Central Register of Controlle ...
DOI:
10.1016/j.numecd.2019.10.001

20. Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study

Author:
Grabež, Milkica; Škrbić, Ranko; Stojiljković, Miloš P.; Rudić-Grujić, Vesna; Paunović, Marija; Arsić, Aleksandra; Petrović, Snježana; Vučić, Vesna; Mirjanić-Azarić, Bosa; Šavikin, Katarina; Menković, Nebojša; Janković, Teodora; Vasiljević, Nađa
Source:
Journal of functional foods 2020 v.64 pp. 103692
ISSN:
1756-4646
Subject:
blood lipids,   etc   ; blood plasma; blood pressure; diabetes mellitus; fatty acid composition; fatty acids; high density lipoprotein cholesterol; low density lipoprotein cholesterol; patients; phytochemicals; placebos; pomegranates; triacylglycerols;     Show all 13 Subjects
Abstract:
... Pomegranate peel contains high levels of various phytochemicals. We evaluated the effects of pomegranate peel extract (PoPEx) consumption on plasma lipid profile, fatty acids (FA) level and blood pressure (BP) in patients with diabetes mellitus type 2 (DMT2). Thirty-seven subjects were recruited in this double blind, placebo controlled randomized trial. The study group (n = 19) received over 8 wee ...
DOI:
10.1016/j.jff.2019.103692