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1. Anchoring red blood cell with tetrahedral DNA nanostructure: Electrochemical biosensor for the sensitive signage of circulating tumor DNA

Author:
Xinyue Zha; Weiwei Qin; Jiadi Chen; Mengting Chen; Qiyue Zhang; Kaiyu He; Yingju Liu; Weipeng Liu
Source:
Talanta 2023 v.251 pp. 123793
ISSN:
0039-9140
Subject:
blood serum,   etc   ; DNA; biocompatibility; biosensors; detection limit; erythrocytes; methylene blue; neoplasms; rapid methods;     Show all 9 Subjects
Abstract:
... Circulating tumor cells (CTCs), as a type of tumor, have attracted wide attention because of their characteristics of shedding from the primary tumor and spreading to other tissues and organs through peripheral blood. The circulating tumor DNA (ctDNA), the DNA released by CTCs and other tumor cells into the peripheral blood, was considered as a promising detection substance for clinical applicatio ...
DOI:
10.1016/j.talanta.2022.123793

2. A novel flower-shaped Ag@ZIF-67 chemiluminescence sensor for sensitive detection of CEA

Author:
Yanan Hou; Jingdao Wang; Shantian Liu; Yuanling Sun; Yuxue Dai; Chuannan Luo; Xueying Wang
Source:
Talanta 2023 v.253 pp. 123938
ISSN:
0039-9140
Subject:
blood serum,   etc   ; antigens; aptasensors; carbon nanotubes; chemiluminescence; detection limit; humans; magnetic fields; oligonucleotides;     Show all 9 Subjects
Abstract:
... In this work, a chemiluminescence (CL) aptasensor for sensitive carcinoembryonic antigen (CEA) detection was constructed based on the CL system of luminol–H₂O₂–NaOH. Magnetic carbon nanotubes (MCNTs), as the base material, was modified with CEA-aptamer and DNA1, and was combined with the novel flower-shaped Ag@ZIF-67 of modified with DNA2 through the principle of base complementary pairing. CEA co ...
DOI:
10.1016/j.talanta.2022.123938

3. Ionic liquid functionalized trapezoidal Zn-MOF nanosheets integrated with gold nanoparticles for photoelectrochemical immunosensing alpha-fetoprotein

Author:
Xinming Qin; Yu Pan; Jiachang Zhang; Jingru Shen; Chunya Li
Source:
Talanta 2023 v.253 pp. 123684
ISSN:
0039-9140
Subject:
blood serum,   etc   ; detection limit; electric current; imidazoles; immunosensors; ionic liquids; ligands; nanocomposites; nanogold; nanosheets;     Show all 10 Subjects
Abstract:
... An imidazolium based ionic liquid was successfully prepared and used as an organic ligand to coordinate with Zn²⁺ to prepare trapezoidal metal-organic frameworks (Zn-MOF) nanosheets. Then, gold nanoparticles (AuNPs) were integrated onto Zn-MOF nanosheets surface to produce AuNPs@Zn-MOF nanocomposites by in-situ reduction of chloroauric acid. AuNPs with size less than 5 nm were uniformly dispersed ...
DOI:
10.1016/j.talanta.2022.123684

4. Development of a colorimetric assay for quantification of favipiravir in human serum using ferrihydrite

Author:
Yukiko Moriiwa; Natsu Oyama; Ryo Otsuka; Kazuhiro Morioka; Atsushi Shoji; Akio Yanagida
Source:
Talanta 2023 v.252 pp. 123827
ISSN:
0039-9140
Subject:
blood serum,   etc   ; COVID-19 infection; colorimetry; computer software; equipment; ferrihydrite; humans; iron; ligands; microbeads;     Show all 10 Subjects
Abstract:
... We developed a colorimetric analytical method for favipiravir (FPV), a promising treatment for COVID-19. FPV forms yellow complexes with ferrihydrite (Fh) by a ligand substitution reaction with the iron (III) hydroxyl surface groups in Fh. Fh-coated microbeads were packed into a capillary tube with an inner diameter of 1 mm. FPV-spiked serum after pretreatment was drawn into the capillary packed w ...
DOI:
10.1016/j.talanta.2022.123827

5. Boron-doped carbon nanowalls for fast and direct detection of cytochrome C and ricin by matrix-free laser desorption/ionization mass spectrometry

Author:
I.S. Hosu; M. Sobaszek; M. Ficek; R. Bogdanowicz; Y. Coffinier
Source:
Talanta 2023 v.252 pp. 123778
ISSN:
0039-9140
Subject:
blood serum,   etc   ; bioterrorism; boron; cytochrome c; databases; desorption; detection limit; galactosamine; graphene; ricin; spectrometers; toxicity;     Show all 12 Subjects
Abstract:
... Detecting proteins via surface assisted laser desorption/ionization mass spectrometry (SALDI-MS) method is still highly challenging, and only few examples of nanomaterials have been demonstrated to perform such detection so far. In this study, carbon nanowalls (CNWs), vertically aligned graphene sheet-based materials, presenting specific morphology, dimensions, and boron doping levels have shown i ...
DOI:
10.1016/j.talanta.2022.123778

6. A near-infrared photoelectrochemical immunosensor for CA72-4 sensing based on SnS nanorods integrated with gold nanoparticles

Author:
Baojun Xu; Wei Li; Chunfeng Lu; Yanying Wang; Chunya Li; Dong Sun
Source:
Talanta 2023 v.253 pp. 123910
ISSN:
0039-9140
Subject:
blood serum,   etc   ; detection limit; electric current; hot water treatment; humans; immunosensors; nanocomposites; nanogold; nanorods; stomach neoplasms;     Show all 10 Subjects
Abstract:
... SnS nanorods with near-infrared photoelectric conversion characteristics were successfully synthesized through a simple hydrothermal method. Gold nanoparticles were self-assembled onto SnS nanorods surface to form SnS/AuNPs nanocomposites. The integration of AuNP can significantly improve the photocurrent response of SnS nanorods under being illuminated with 808 nm near-infrared light. A near-infr ...
DOI:
10.1016/j.talanta.2022.123910

7. Electrochemiluminescence biosensor for DNA adenine methylation methyltransferase based on CRISPR/Cas12a trans-cleavage-induced dual signal enhancement

Author:
Cuiying Lin; Qingqing Huang; Mengjian Tian; Fang Luo; Jian Wang; Bin Qiu; Shuofei Yang; Zhenyu Lin
Source:
Talanta 2023 v.251 pp. 123748
ISSN:
0039-9140
Subject:
blood serum,   etc   ; DNA; adenine; biosensors; detection limit; electrochemiluminescence; electrodes; ferrocenes; indium; methylation; methyltransferases; restriction endonucleases; tin;     Show all 13 Subjects
Abstract:
... In this work, an electrochemiluminescence (ECL) biosensor with dual signal enhancement was constructed and used for DNA adenine methylation methyltransferase (Dam MTase) detection. At present of Dam MTase, restriction endonuclease (DPnI) cleaves hairpin DNA (HP) and releases the HP stem end as a single strand that can activate CRISPR/Cas12a trans-cleavage activity. Assisted by trans-cleavage, the ...
DOI:
10.1016/j.talanta.2022.123748

8. Low temperature microfiltration of skim milk: Impact of membrane type, configuration and concentration factor on serum protein permeation efficiency

Author:
Surabhi Subhir; Paul L.H. McSweeney; Mark A. Fenelon; John T. Tobin
Source:
International dairy journal 2023 v.137 pp. 105500
ISSN:
0958-6946
Subject:
blood serum,   etc   ; blood proteins; crude protein; energy; microfiltration; molecular weight; permeability; polymers; porosity; skim milk; temperature;     Show all 11 Subjects
Abstract:
... Protein transmission, permeate flux and energy consumption during MF of skim milk was evaluated at 7 °C using two discrete 800 kDa polymeric MF membranes. Filtration trials determined optimum process parameters (i.e., transmembrane pressure and volume concentration factor) and membrane configuration (in-series or in-parallel) to maximise serum protein permeation. This study demonstrated that a com ...
DOI:
10.1016/j.idairyj.2022.105500

9. Edible mushrooms as a potent therapeutics of subclinical thyroid dysfunction among adults, especially in obese individuals: a prospective cohort study

Author:
Juanjuan Zhang; Sabina Rayamajhi; Amrish Thapa; Ge Meng; Qing Zhang; Li Liu; Hongmei Wu; Yeqing Gu; Shunming Zhang; Tingjing Zhang; Xuena Wang; Zhixia Cao; Jun Dong; Xiaoxi Zheng; Xu Zhang; Xinrong Dong; Xing Wang; Shaomei Sun; Ming Zhou; Qiyu Jia; Kun Song; Kaijun Niu
Source:
Food science and human wellness 2023 v.12 no.1 pp. 295-302
ISSN:
2213-4530
Subject:
blood serum,   etc   ; adults; cohort studies; food frequency questionnaires; food science; humans; hyperthyroidism; hypothyroidism; therapeutics; thyrotropin; thyroxine;     Show all 11 Subjects
Abstract:
... Mushrooms are a good source of many nutrients which are potentially beneficial for chronic diseases. We speculated that due to its abundant nutrients edible mushrooms might have a beneficial effect on the prevention of subclinical thyroid dysfunction (SCTD). Therefore, we designed a large-scale cohort study to examine whether mushrooms consumption is a protective factor for SCTD in adults. This pr ...
DOI:
10.1016/j.fshw.2022.07.019

10. Target and suspect analysis of liquid crystal monomers in soil from different urban functional zones

Author:
Rongrong Li; Kefan Ren; Huijun Su; Yu Wei; Guanyong Su
Source:
Science of the total environment 2023 v.854 pp. 158408
ISSN:
0048-9697
Subject:
blood serum,   etc   ; agricultural zoning; databases; dust; environment; gas chromatography; humans; liquid crystals; mass spectrometry; sediments; soil;     Show all 11 Subjects
Abstract:
... Recent studies have reported the occurrence of liquid crystal monomers (LCMs) in sediment, indoor dust, hand wipes, and human serum samples; however, information regarding their contamination status in soil is currently unavailable. The concentrations of 39 target LCMs were determined in n = 96 surface soil samples collected from five different urban functional zones including agricultural, scenic ...
DOI:
10.1016/j.scitotenv.2022.158408

11. A microfluidic electrochemical aptasensor for highly sensitive and selective detection of A549 cells as integrin α6β4-containing cell model via IDA aptamers

Author:
Sedighe Khaksari; Amir Reza Ameri; Seyed Mohammad Taghdisi; Mahya Sabet; Seyed Mohammad Javad Ghaani Bami; Khalil Abnous; Seyed Ali Mousavi Shaegh
Source:
Talanta 2023 v.252 pp. 123781
ISSN:
0039-9140
Subject:
blood serum,   etc   ; aptasensors; biomarkers; biopsy; detection limit; electrochemistry; electrodes; gold; humans; integrins; microchip technology; models; neoplasm cells; oligonucleotides;     Show all 14 Subjects
Abstract:
... There is a growing interest in developing microfluidic biosensors for the accurate and reproducible analysis of various biomarkers obtained from liquid biopsy. This paper reports a novel microfluidic electrochemical aptasensor for determination of A549 cells as integrin α6β4-containing cell model and circulating tumor cell (CTC) model of NSCLC, based on target-induced structure switching mode. The ...
DOI:
10.1016/j.talanta.2022.123781

12. Source apportionment of serum PFASs in two highly exposed communities

Author:
Dylan J. Wallis; Kelsey E. Barton; Detlef R.U. Knappe; Nadine Kotlarz; Carrie A. McDonough; Christopher P. Higgins; Jane A. Hoppin; John L. Adgate
Source:
Science of the total environment 2023 v.855 pp. 158842
ISSN:
0048-9697
Subject:
blood serum,   etc   ; National Health and Nutrition Examination Survey; environment; humans; nutrition; principal component analysis; regression analysis; Colorado; North Carolina;     Show all 9 Subjects
Abstract:
... Per- and polyfluoroalkyl substances (PFASs) are synthetic chemicals that are ubiquitous in environmental and biological systems, including human serum. PFASs are used in many products and industrial processes and are tied to numerous health effects. Due to multiple sources and exposure pathways, methods are needed to identify PFAS sources in communities to develop targeted interventions. We assess ...
DOI:
10.1016/j.scitotenv.2022.158842

13. Smartphone recognition-based immune microparticles for rapid on-site visual data-sharing detection of Newcastle disease virus

Author:
Shenjunjie Lu; Binglin Ma; Haoran Zhou; Yayang Li; Zhihao Qiao; Tong Xiao; Husheng Li; Baijie Wang; Meihui Cui; Shufang Zhang; Jin Chang; Taofeng Du; Jing Liu; Hanjie Wang
Source:
Talanta 2023 v.252 pp. 123845
ISSN:
0039-9140
Subject:
blood serum,   etc   ; Avian orthoavulavirus 1; antibodies; color; human resources; humans; hydrogels; image analysis; industry; mobile telephones; nucleocapsid proteins; viruses;     Show all 12 Subjects
Abstract:
... Since the last century, animal viruses have posed great threats to the health of humans and the farming industry. Therefore, virus control is of great urgency, and regular, timely, and accurate detection is essential to it. Here, we designed a rapid on-site visual data-sharing detection method for the Newcastle disease virus with smartphone recognition-based immune microparticles. The detection me ...
DOI:
10.1016/j.talanta.2022.123845

14. Immunomodulatory efficacy of Cousinia thomsonii C.B. Clarke in ameliorating inflammatory cascade expressions

Author:
Khalid Bashir Dar; Ruhban Ansar Parry; Aashiq Hussain Bhat; Afaq Hameed Beigh; Maroof Ahmed; Umer Majeed Khaja; Aijaz Hassan Ganie; Manzoor Ahmad Mir; Bilal Ahmad Reshi; Ishfaq Shafi Khan; Showkat Ahmad Ganie
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115727
ISSN:
0378-8741
Subject:
blood serum,   etc   ; Cousinia; arthritis; asthma; cough; decline; dermatitis; dexamethasone; dose response; energy; immunoblotting; lipopolysaccharides; methanol; models; pain; therapeutics; traditional medicine;     Show all 17 Subjects
Abstract:
... Cousinia thomsonii is traditionally known for treating various diseases including joint pain, swelling, body ache, asthma, dermatitis, cough and arthritis. This study employs lipopolysaccharide induced inflammatory wistar-rat model to evaluate efficacy of Cousinia thomsonii active-extracts on the expression of crucial inflammatory markers viz. iNOS, PPAR-γ, Rel-A, COX-2 and serum analysis of CRP.  ...
DOI:
10.1016/j.jep.2022.115727

15. Confined catalysis of MOF-818 nanozyme and colorimetric aptasensing for cardiac troponin I

Author:
Ruiting Wen; Chunhong Zhou; Jiuying Tian; Jusheng Lu
Source:
Talanta 2023 v.252 pp. 123830
ISSN:
0039-9140
Subject:
blood serum,   etc   ; aptasensors; catalytic activity; colorimetry; detection limit; enzyme inhibition; enzyme kinetics; humans; oxidation; porous media; troponin I; tungsten oxide;     Show all 12 Subjects
Abstract:
... Understanding the catalytic performance of nanozymes assembled in confined environment is an interesting topic. Herein, a three-dimensional nanozyme-catalytic nanoreactor was constructed by confining MOF-818 nanozyme in the pore of macroporous tungsten trioxide (p-WO₃). The catalytic activity of MOF-818 assembled in-situ for the oxidation of 3,5-Di-tert-butylcatechol (3,5-DTBC) could be regulated ...
DOI:
10.1016/j.talanta.2022.123830

16. XCHT alleviates the pancreatic fibrosis via VDR/NLRP3 signaling pathway in a mouse model of CP

Author:
Guixian Zhang; Xiumei Zhao; Jun Cai; Sainan Li; Xijing Li; Wenchang Li; Pengcheng Shi; Dawei Liu; Duo Zheng; Ting Zhang; Renrui Feng; Hongbin Liu
Source:
Journal of ethnopharmacology 2023 v.300 pp. 115689
ISSN:
0378-8741
Subject:
blood serum,   etc   ; actin; collagen; fibrosis; immunohistochemistry; inflammasomes; inflammation; interleukin-6; males; mice; models; muscles; pancreatitis; secretion; therapeutics; traditional medicine; China;     Show all 17 Subjects
Abstract:
... Xiao Chai Hu Tang (XCHT) derived from the classic medical book Shang Han Lun (Treatise on Febrile Diseases) in the Eastern Han Dynasty, which has been widely used in China and other Asian countries for the treatment of inflammation and fibrosis of chronic pancreatitis (CP), but the therapeutic mechanism of XCHT in pancreatic fibrosis remains unclear. This study aimed to evaluate the intervention e ...
DOI:
10.1016/j.jep.2022.115689

17. Environmental microcystin exposure triggers the poor prognosis of prostate cancer: Evidence from case-control, animal, and in vitro studies

Author:
Chun Pan; Haixiang Qin; Minghao Yan; Xuefeng Qiu; Wenyue Gong; Wenxin Luo; Hongqian Guo; Xiaodong Han
Source:
Journal of environmental sciences (China) 2023 v.127 pp. 69-81
ISSN:
1001-0742
Subject:
blood serum,   etc   ; cadherins; estrogens; humans; lungs; metastasis; microcystin-LR; migratory behavior; odds ratio; prognosis; prostatic neoplasms; risk; toxicity; vimentin; xenotransplantation; China;     Show all 16 Subjects
Abstract:
... Microcystin-leucine-arginine (MC-LR) is positively linked with multiple cancers in humans. However, the association between MC-LR and the risk and prognosis of prostate cancer has not been conducted in epidemiological studies. No reported studies have linked MC-LR exposure to the poor prognosis of prostate cancer by conducting experimental studies. The content of MC-LR was detected in most of the ...
DOI:
10.1016/j.jes.2022.05.051

18. Accumulation and risk prioritization of psychoactive substances in the critically endangered Yangtze finless porpoise

Author:
Zeyuan Wang; Bin Tang; Kexiong Wang; Yujiang Hao; Fangxing Yang
Source:
Journal of hazardous materials 2023 v.442 pp. 130002
ISSN:
0304-3894
Subject:
blood serum,   etc   ; aquatic environment; codeine; endangered species; humans; lakes; methamphetamines; morphine; prioritization; psychotropic agents; risk; risk analysis; therapeutics; watersheds; China; Yangtze River;     Show all 16 Subjects
Abstract:
... Psychoactive substances have been identified as a kind of emerging contaminants in aquatic environment and pose potential adverse effects on aquatic animals. Yangtze finless porpoise, a critically endangered species in China, is also facing the threat of psychoactive substances. In this study, the accumulation characteristics and risk prioritization of psychoactive substances were investigated in ...
DOI:
10.1016/j.jhazmat.2022.130002

19. Serum metabolite signatures in normal individuals and patients with colorectal adenoma or colorectal cancer using UPLC-MS/MS method

Author:
Jiachi Guo; Yuanming Pan; Jigui Chen; Peng Jin; Shan Tang; Haihong Wang; Hui Su; Qian Wang; Chao Chen; Fei Xiong; Kejia Liu; Yansheng Li; Mingliang Su; Tang Tang; Yuqi He; Jianqiu Sheng
Source:
Journal of proteomics 2023 v.270 pp. 104741
ISSN:
1874-3919
Subject:
blood serum,   etc   ; adenocarcinoma; adenoma; biomarkers; carcinogenesis; chenodeoxycholic acid; colorectal neoplasms; cysteine; developmental stages; early diagnosis; intestines; mannose; metabolites; mucosa; prediction; proteomics; sarcosines;     Show all 17 Subjects
Abstract:
... Colorectal cancer (CRC) is one of the main causes of cancer-related deaths worldwide. Sporadic CRC develops from normal mucosa via adenoma to adenocarcinoma, which provides a long screening window for clinical detection. However, early diagnosis of sporadic colorectal adenoma (CRA) and CRC using serum metabolic screening remains unclear. The purpose of this study was to identify some promising sig ...
DOI:
10.1016/j.jprot.2022.104741

20. Association between serum levels of TSH and free T4 and per- and polyfluoroalkyl compounds concentrations in pregnant women

Author:
Aijing Li; Jian Hou; Jianjie Fu; Yinan Wang; Yifei Hu; Taifeng Zhuang; Menglong Li; Maoyong Song; Guibin Jiang
Source:
Journal of environmental sciences (China) 2023 v.124 pp. 11-18
ISSN:
1001-0742
Subject:
blood serum,   etc   ; antibodies; early development; fetal development; homeostasis; iodide peroxidase; pregnancy; regression analysis; thyroid function; thyroid hormones; thyrotropin; thyroxine; weight gain; China;     Show all 14 Subjects
Abstract:
... Many per- and polyfluoralkyl substances (PFASs) may disrupt maternal thyroid hormone homeostasis in pregnancy. Concerns should be raised regarding the PFASs exposure in pregnant women because thyroid hormones are involved in the early development of the fetus. In this study, we measured the concentrations of 13 PFASs, including five novel short-chain PFASs, in serum from 123 pregnant women in Beij ...
DOI:
10.1016/j.jes.2021.10.026