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1. Evaluation of the Mandibular Condyle Morphologic Relation before and after Orthognathic Surgery in Class II and III Malocclusion Patients Using Cone Beam Computed Tomography

Author:
Raluca Roman; Oana Almășan; Mihaela Hedeșiu; Mihaela Băciuț; Simion Bran; Daiana Popa; Alina Ban; Cristian Dinu
Source:
Biology 2022 v.11 no.9 pp. -
ISSN:
2079-7737
Subject:
bones,   etc   ; malocclusion; osteotomy; tomography;     Show all 4 Subjects
Abstract:
... This study aimed at evaluating the mandibular condyle position changes before and after bimaxillary orthognathic surgery in class II and III malocclusion patients. CBCT scans from patients who underwent bimaxillary orthognathic surgery were analyzed: Le Fort I osteotomy and bilateral sagittal split osteotomy (BSSO). Both condyles were independently assessed for their largest anterior and posterior ...
DOI:
10.3390/biology11091353

2. Progress in 3D printing for bone tissue engineering: a review

Author:
Weiwei Lan; Xiaobo Huang; Di Huang; Xiaochun Wei; Weiyi Chen
Source:
Journal of materials science 2022 v.57 no.27 pp. 12685-12709
ISSN:
0022-2461
Subject:
bones,   etc   ; hydrogels; magnetism; tomography;     Show all 4 Subjects
Abstract:
... Effective clinical methods for large bone defects are not yet available on account of the complex intrinsic structure and mechanical characteristics of natural bone tissue. It remains a challenge to restore bone damage to its original form by tissue engineering. With the continuous development of three-dimensional (3D) printing in recent years, the emergence of new technical supports and material ...
DOI:
10.1007/s10853-022-07361-y

3. Oxidative Damage in Korean Medicine

Author:
Gunhyuk Park
Source:
Antioxidants 2022 v.11 no.3 pp. -
ISSN:
2076-3921
Subject:
bones,   etc   ; Koreans; antioxidants; boning; medicine;     Show all 5 Subjects
Abstract:
... Korean medicine originated in ancient and prehistoric times, as evidenced by the discovery of stone and bone needles in the North Hamgyeong Province, dating back to 3000 BC [...] ...
DOI:
10.3390/antiox11030600

4. Tough Photo-Cross-Linked PCL-Hydroxyapatite Composites for Bone Tissue Engineering

Author:
Quinten Thijssen; Kim Cornelis; Rand Alkaissy; Janis Locs; Lana Van Damme; David Schaubroeck; Robin Willaert; Sarah Snelling; Pierre-Alexis Mouthuy; Sandra Van Vlierberghe
Source:
Biomacromolecules 2022 v.23 no.3 pp. 1366-1375
ISSN:
1526-4602
Subject:
bones,   etc   ; crosslinking; hydroxyapatite; osteoblasts; polymerization;     Show all 5 Subjects
Abstract:
... Acrylate-based photo-cross-linked poly(ε-caprolactone) (PCL) tends to show low elongation and strength. Incorporation of osteo-inductive hydroxyapatite (HAp) further enhances this effect, which limits its applicability in bone tissue engineering. To overcome this, the thiol–ene click reaction is introduced for the first time in order to photo-cross-link PCL composites with 0, 10, 20, and 30 wt % H ...
DOI:
10.1021/acs.biomac.1c01584

5. Fretting stimulation enhances bone growth at the interface between hydroxyapatite coating and bone

Author:
Kai Chen; Yujie Zhao; Yueru Zhang; Dong Yan; Yu Zhang; Xiangyang Li; Cunao Feng; Xiaowei Li; Dekun Zhang
Source:
Colloids and surfaces 2022 v.217 pp. 112669
ISSN:
0927-7765
Subject:
bones,   etc   ; alloys; hydroxyapatite; prostheses; titanium;     Show all 5 Subjects
Abstract:
... Biologically fixed arthroplasty is limited in its development by the long postoperative recovery time and the low quality of solidity of the fixed interface in the short postoperative period. Therefore, fretting stimulation is used to accelerate the combination between bone tissue and the biological fixation interface of artificial joint prostheses. The effects of different compression loads and t ...
DOI:
10.1016/j.colsurfb.2022.112669

6. Analysis of Urotomy and Regeneration in Agamid Lizards of the Genus Mantheyus (Reptilia: Sauria: Agamidae: Draconinae) Using X-ray Methods and a Computed Microtomography

Author:
N. B. Ananjeva; D. A. Gordeev; Nguyen Thien Tao; N. L. Orlov
Source:
Biology bulletin of the Russian Academy of Sciences 2022 v.49 no.4 pp. 309-317
ISSN:
1062-3590
Subject:
spine (bones),   etc   ; Agamidae; X-radiation; phylogeny;     Show all 4 Subjects
Abstract:
... The results of an analysis of manifestations and combinations of urotomy and regeneration in the caudal part of the vertebral column in agamid lizards of the subfamily Draconinae Fitzinger, 1826 are considered based on the material stored in museums around the world. The methods of X-ray analysis and computed microtomography (CT) were used based on our own data and the data on skeletal morphology ...
DOI:
10.1134/S1062359022040033

7. Giant Functional Properties in Porous Electroceramics through Additive Manufacturing of Capillary Suspensions

Author:
David Menne; Lucas Lemos da Silva; Magnus Rotan; Julia Glaum; Manuel Hinterstein; Norbert Willenbacher
Source:
ACS applied materials & interfaces 2022 v.14 no.2 pp. 3027-3037
ISSN:
1944-8252
Subject:
bones,   etc   ; barium titanate; cell growth; electrodes; energy; porosity;     Show all 6 Subjects
Abstract:
... Dedicated hierarchical structuring of functional ceramics can be used to shift the limits of functionality. This work presents the manufacturing of highly open porous, hierarchically structured barium titanate ceramics with 3-3 connectivity via direct ink writing of capillary suspension-type inks. The pore size of the printed struts (∼1 μm) is combined with a printed mesostructure (∼100 μm). The s ...
DOI:
10.1021/acsami.1c19297

8. Osteosynthesis Metal Plate System for Bone Fixation Using Bicortical Screws: Numerical–Experimental Characterization

Author:
Andrea A. R. Olmos; Aureliano Fertuzinhos; Teresa D. Campos; Isabel R. Dias; Carlos A. Viegas; Fábio A. M. Pereira; Nguyễn T. Quyền; Marcelo F. S. F. de Moura; Andrea Zille; Nuno Dourado
Source:
Biology 2022 v.11 no.6 pp. -
ISSN:
2079-7737
Subject:
bones,   etc   ; fracture fixation; mathematical models; mechanical properties; neutralization;     Show all 5 Subjects
Abstract:
... This study reports the numerical and experimental characterization of a standard immobilization system currently being used to treat simple oblique bone fractures of femoral diaphyses. The procedure focuses on the assessment of the mechanical behavior of a bone stabilized with a dynamic compression plate (DCP) in a neutralization function, associated to a lag screw, fastened with surgical screws. ...
DOI:
10.3390/biology11060940

9. A 3D-printed biphasic calcium phosphate scaffold loaded with platelet lysate/gelatin methacrylate to promote vascularization

Author:
Gang Liu; Boqing Zhang; Ting Wan; Changchun Zhou; Yujiang Fan; Weidong Tian; Wei Jing
Source:
Journal of materials chemistry B 2022 v.10 no.16 pp. 3138-3151
ISSN:
2050-7518
Subject:
bones,   etc   ; blood; calcium phosphates; cell proliferation; coculture; gelatin;     Show all 6 Subjects
Abstract:
... 3D-printed biphasic calcium phosphate (BCP) scaffolds show great clinical application potential in bone tissue engineering; however, vascularization of the scaffold is a crucial step for bone regeneration and is still difficult to be controlled. To enhance scaffold vascularization, a novel bioactive scaffold loaded with platelet lysate/gelatin methacrylate (PL/GelMA) in a BCP scaffold was proposed ...
DOI:
10.1039/d2tb00006g

10. Applications of bone regeneration hydrogels in the treatment of bone defects: a review

Author:
Yukun Xiong; Yuzhu Xiong
Source:
Journal of materials science 2022 v.57 no.2 pp. 887-913
ISSN:
0022-2461
Subject:
bones,   etc   ; angiogenesis; biocompatibility; hydrogels; immune response; mineralization; osteoblasts;     Show all 7 Subjects
Abstract:
... Hydrogels can be designed as scaffolds in bone tissue engineering for more efficient healing of bone defects. Bone regeneration hydrogels have attracted extensive attention because of their good biocompatibility and excellent ability in promoting bone regeneration. This review will introduce the methods of bone regeneration hydrogels in the treatment of bone defects. Namely, promoting differentiat ...
DOI:
10.1007/s10853-021-06675-7

11. Manufacturing functional hydrogels for inducing angiogenic–osteogenic coupled progressions in hard tissue repairs: prospects and challenges

Author:
Anuj Kumar; Ankur Sood; Ritu Singhmar; Yogendra Kumar Mishra; Vijay Kumar Thakur; Sung Soo Han
Source:
Biomaterials science 2022 v.10 no.19 pp. 5472-5497
ISSN:
2047-4849
Subject:
bones,   etc   ; angiogenesis; biocompatible materials; blood; bone mineralization; hydrogels; manufacturing;     Show all 7 Subjects
Abstract:
... In large bone defects, inadequate vascularization within the engineered constructs has been a major challenge in developing clinically impactful products. It is fairly determined that bone tissues and blood vessels are established concurrently throughout tissue repairs after an injury. Thus, the coupling of angiogenesis–osteogenesis is an essential course of action in bone tissue restoration. The ...
DOI:
10.1039/d2bm00894g

12. Fabrication and Characterization of Bioactive Gelatin–Alginate–Bioactive Glass Composite Coatings on Porous Titanium Substrates

Author:
Belen Begines; Cristina Arevalo; Carlos Romero; Zoya Hadzhieva; Aldo R. Boccaccini; Yadir Torres
Source:
ACS applied materials & interfaces 2022 v.14 no.13 pp. 15008-15020
ISSN:
1944-8252
Subject:
bones,   etc   ; alginates; cartilage; gelatin; glass; microstructure; polymers; porosity; titanium;     Show all 9 Subjects
Abstract:
... In this research work, the fabrication of biphasic composite implants has been investigated. Porous, commercially available pure Ti (50 vol % porosity and pore distributions of 100–200, 250–355, and 355–500 μm) has been used as a cortical bone replacement, while different composites based on a polymer blend (gelatin and alginate) and bioactive glass (BG) 45S5 have been applied as a soft layer for ...
DOI:
10.1021/acsami.2c01241

13. Osteogenic differentiation of human mesenchymal stem cells on substituted calcium phosphate/chitosan composite scaffold

Author:
Antonia Ressler; Maja Antunović; Laura Teruel-Biosca; Gloria Gallego Ferrer; Slaven Babić; Inga Urlić; Marica Ivanković; Hrvoje Ivanković
Source:
Carbohydrate polymers 2022 v.277 pp. 118883
ISSN:
0144-8617
Subject:
bones,   etc   ; bone formation; calcium; calcium phosphates; chitosan; humans; immunohistochemistry;     Show all 7 Subjects
Abstract:
... Ionic substitutions are a promising strategy to enhance the biological performance of calcium phosphates (CaP) and composite materials for bone tissue engineering applications. However, systematic studies have not been performed on multi-substituted organic/inorganic scaffolds. In this work, highly porous composite scaffolds based on CaPs substituted with Sr²⁺, Mg²⁺, Zn²⁺ and SeO₃²⁻ ions, and chit ...
DOI:
10.1016/j.carbpol.2021.118883

14. Study on synergistic effects of carboxymethyl cellulose and LIPUS for bone tissue engineering

Author:
Liang Tang; Tianpei Wu; Yaling Zhou; Yi Zhong; Lijun Sun; Jianzhong Guo; Xiushan Fan; Dean Ta
Source:
Carbohydrate polymers 2022 v.286 pp. 119278
ISSN:
0144-8617
Subject:
bones,   etc   ; bone formation; carboxymethylcellulose; osteoblasts; ramie; sodium monochloroacetate; ultrasonics;     Show all 7 Subjects
Abstract:
... In this research, the pharmaceutical used carboxymethyl cellulose (CMC) was successfully synthesized by ramie fiber and sodium monochloroacetate. Meanwhile, this study focused on the proliferation and differentiation of osteoblast which was stimulated by ramie based CMC. Additionally, the synergistic effects between CMC and Low-intensity pulsed ultrasound (LIPUS) for the proliferation and differen ...
DOI:
10.1016/j.carbpol.2022.119278

15. A brief review of mRNA therapeutics and delivery for bone tissue engineering

Author:
Arun Kumar Rajendran; Sivashanmugam Amirthalingam; Nathaniel S. Hwang
Source:
RSC advances 2022 v.12 no.15 pp. 8889-8900
ISSN:
2046-2069
Subject:
bones,   etc   ; cost effectiveness; half life; ribonucleases; therapeutics; tissue repair;     Show all 6 Subjects
Abstract:
... The therapeutics for bone tissue regeneration requires constant advancements owing to the steady increase in the number of patients suffering from bone-related disorders, and also to find efficient and cost-effective treatment modalities. One of the major advancements in the field of therapeutics is the development of mRNAs. mRNAs, which have been extensively tested for the vaccines, could be very ...
DOI:
10.1039/d2ra00713d

16. The osteogenic effects of porous Tantalum and Titanium alloy scaffolds with different unit cell structure

Author:
Gan Huang; Shu-Ting Pan; Jia-Xuan Qiu
Source:
Colloids and surfaces 2022 v.210 pp. 112229
ISSN:
0927-7765
Subject:
bones,   etc   ; alloys; bone formation; rats; strength (mechanics); tantalum; titanium;     Show all 7 Subjects
Abstract:
... Porous scaffolds have long been regarded as optimal substitute for bone tissue repairing. In order to explore the influence of unit cell structure and inherent material characteristics on the porous scaffolds in terms of mechanical and biological performance, selective laser melting (SLM) technology was used to fabricate porous tantalum (Ta) and titanium alloy (Ti6Al4V) with diamond (Di) or rhombi ...
DOI:
10.1016/j.colsurfb.2021.112229

17. The osteogenic response to chirality-patterned surface potential distribution of CFO/P(VDF-TrFE) membranes

Author:
Jiamin Zhang; Xuzhao He; Zhiyuan Zhou; Xiaoyi Chen; Jiaqi Shao; Donghua Huang; Lingqing Dong; Jun Lin; Huiming Wang; Wenjian Weng; Kui Cheng
Source:
Biomaterials science 2022 v.10 no.16 pp. 4576-4587
ISSN:
2047-4849
Subject:
bones,   etc   ; biocompatible materials; bone formation; cytoskeleton; electrophysiology; integrins; microelectrodes; topology;     Show all 8 Subjects
Abstract:
... Piezoelectric poly(vinylidene fluoride-trifluoroethylene) has demonstrated an ability to promote osteogenesis, and biomaterials with a chirality-patterned topological surface could enhance cellular osteogenic differentiation. In this work, we created a chirality-patterned surface potential distribution of CoFe₂O₄/poly(vinylidene fluoride-trifluoroethylene (CFO/P(VDF-TrFE)) membranes to explore the ...
DOI:
10.1039/d2bm00186a

18. Beta-tricalcium phosphate enhanced mechanical and biological properties of 3D-printed polyhydroxyalkanoates scaffold for bone tissue engineering

Author:
Xiangling Ye; Yongqiang Zhang; Tao Liu; Zehua Chen; Weijian Chen; Zugui Wu; Yi Wang; Junyi Li; Congcong Li; Tao Jiang; Ying Zhang; Huai Wu; Xuemeng Xu
Source:
International journal of biological macromolecules 2022 v.209 pp. 1553-1561
ISSN:
0141-8130
Subject:
bones,   etc   ; adhesion; bioactive properties; biocompatibility; compression strength; hardness; phosphates; polyhydroxyalkanoates;     Show all 8 Subjects
Abstract:
... Polyhydroxyalkanoates (PHA) is a naturally degradable polyester with good biocompatibility. However, several disadvantages including poor bioactivity and mechanical properties limit the biomedical application of PHA. To circumvent these drawbacks, PHA needs to be blended with other materials to improve performance. Beta-tricalcium phosphate (β-TCP) has emerged as one of the most promising bone rep ...
DOI:
10.1016/j.ijbiomac.2022.04.056

19. Bacterial cellulose-based biomaterials: From fabrication to application

Author:
Chuntao Chen; Weixiao Ding; Heng Zhang; Lei Zhang; Yang Huang; Mengmeng Fan; Jiazhi Yang; Dongping Sun
Source:
Carbohydrate polymers 2022 v.278 pp. 118995
ISSN:
0144-8617
Subject:
bones,   etc   ; artificial skin; biocompatible materials; cellulose; drugs; extracellular matrix; tissue repair;     Show all 7 Subjects
Abstract:
... Driven by its excellent physical and chemical properties, BC (bacterial cellulose) has achieved significant progress in the last decade, rendering with many novel applications. Due to its resemblance to the structure of extracellular matrix, BC-based biomaterials have been widely explored for biomedical applications such as tissue engineering and drug delivery. The recent advances in nanotechnolog ...
DOI:
10.1016/j.carbpol.2021.118995

20. Enzymatically functionalized RGD-gelatin scaffolds that recruit host mesenchymal stem cells in vivo and promote bone regeneration

Author:
Junling Li; Yan Zhang; Xing Zhou; Shili Wang; Ruirui Hao; Jinxiang Han; Mian Li; Yurong Zhao; Cuixia Chen; Hai Xu
Source:
Journal of colloid and interface science 2022 v.612 pp. 377-391
ISSN:
0021-9797
Subject:
bones,   etc   ; bone formation; bone transplantation; gelatin; mice; skeletal muscle; tissue repair;     Show all 7 Subjects
Abstract:
... Critical-size bone defects are imposing a substantial biomedical burden. Despite being long regarded as a potential approach to mitigate this burden or an alternative to bone grafts, bone tissue engineering (BTE) has virtually not proceeded to widespread clinical practices. In the BTE field, it is highly required to find a facile method to prepare active scaffolds with tailored biological function ...
DOI:
10.1016/j.jcis.2021.12.091