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1. Mining the Core Gut Microbiome from a Sample Indian Population

Author:
Kulkarni, Abhijit S.; Kumbhare, Shreyas V.; Dhotre, Dhiraj. P.; Shouche, Yogesh S.
Source:
Indian journal of microbiology 2019 v.59 no.1 pp. 90-95
ISSN:
0046-8991
Subject:
carbohydrate metabolism,   etc   ; Bacteroides; Megasphaera; Prevotella; Roseburia; digestive system; feces; genes; humans; intestinal microorganisms; microbiome; ribosomal RNA; sampling; India;     Show all 14 Subjects
Abstract:
... Human gut microbiome studies are increasing at a rapid pace to understand contributions of the prokaryotic life to the innate workings of their eukaryotic host. Majority of studies focus on the pattern of gut microbial diversity in various diseases, however, understanding the core microbiota of healthy individuals presents a unique opportunity to study the microbial fingerprint in population speci ...
DOI:
10.1007/s12088-018-0742-0

2. Ambient fine particulate matter exposure induces cardiac functional injury and metabolite alterations in middle-aged female mice

Author:
Zhang, Yingying; Ji, Xiaotong; Ku, Tingting; Li, Ben; Li, Guangke; Sang, Nan
Source:
Environmental pollution 2019 v.248 pp. 121-132
ISSN:
0269-7491
Subject:
carbohydrate metabolism,   etc   ; adults; amino acid metabolism; cardiac output; cardiotoxicity; cardiovascular diseases; epidemiological studies; fatty acid metabolism; females; metabolic diseases; metabolites; mice; mitochondria; nicotinamide; particulates; ultrastructure;     Show all 16 Subjects
Abstract:
... Plenty of epidemiological studies have shown that exposure to ambient particulate matter (PM2.5) is linked to cardiovascular diseases (CVDs) in older even in middle-aged populations; however, experimental evidence through intuitive metabolic analysis to confirm the age susceptibility and explain the related molecular mechanism of PM2.5-induced cardiotoxicity is relatively rare. In the present stud ...
DOI:
10.1016/j.envpol.2019.01.080

3. A novel crustacean hyperglycemic hormone (CHH) from the mud crab Scylla paramamosain regulating carbohydrate metabolism

Author:
Liu, An; Liu, Jing; Chen, Xuelei; Lu, Bei; Zeng, Chaoshu; Ye, Haihui
Source:
Comparative biochemistry and physiology 2019 v.231 pp. 49-55
ISSN:
1095-6433
Subject:
carbohydrate metabolism,   etc   ; RNA interference; Scylla paramamosain; complementary DNA; crabs; double-stranded RNA; glucose; hemolymph; phylogeny; signal peptide; starvation; stomach; thoracic ganglia; tissue distribution;     Show all 14 Subjects
Abstract:
... Crustacean hyperglycemic hormone (CHH) plays a crucial role in regulating carbohydrate metabolism in crustaceans. In this study, a new cDNA encoding type I CHH peptide, termed Sp-CHH3, was isolated from the mud crab Scylla paramamosain and its potential functions were investigated. The full length cDNA of Sp-CHH3 was identified as encoding a 127-aa precursor composed of a 27-aa signal peptide, a 2 ...
DOI:
10.1016/j.cbpa.2019.01.015

4. Effect of exogenous ATP treatment on sucrose metabolism and quality of Nanguo pear fruit

Author:
Duan, Bin; Ge, Yonghong; Li, Canying; Gao, Xiaonan; Tang, Qi; Li, Xue; Wei, Meilin; Chen, Yanru
Source:
Scientia horticulturae 2019 v.249 pp. 71-76
ISSN:
0304-4238
Subject:
carbohydrate metabolism,   etc   ; adenosine triphosphate; ambient temperature; beta-fructofuranosidase; enzyme activity; firmness; fruit quality; fruits; pears; postharvest treatment; storage temperature; sucrose; total soluble solids;     Show all 13 Subjects
Abstract:
... Nanguo pear fruits were used as materials to investigate the effect of exogenous ATP treatment on the quality and sucrose metabolism during storage at room temperature (20 ± 1 °C, RH 45 ± 2%). The changes of weight loss, respiratory intensity, total soluble solids (TSS) content, flesh firmness and the activity of enzymes in sucrose metabolism were studied. The results indicated that ATP at 0.8 mM ...
DOI:
10.1016/j.scienta.2019.01.047

5. Discovery and Characterization of FMN-Binding β-Glucuronidases in the Human Gut Microbiome

Author:
Pellock, Samuel J.; Walton, William G.; Ervin, Samantha M.; Torres-Rivera, Dariana; Creekmore, Benjamin C.; Bergan, Grace; Dunn, Zachary D.; Li, Bo; Tripathy, Ashutosh; Redinbo, Matthew R.
Source:
Journal of molecular biology 2019 v.431 no.5 pp. 970-980
ISSN:
0022-2836
Subject:
carbohydrate metabolism,   etc   ; Roseburia hominis; Ruminococcus gnavus; X-ray diffraction; active sites; calorimetry; databases; digestive system; drugs; glycosides; humans; hydrolases; intestinal microorganisms; kinetics; mass spectrometry; metagenomics; microbiome; mutants; titration;     Show all 19 Subjects
Abstract:
... The human gut microbiota encodes β-glucuronidases (GUSs) that play key roles in health and disease via the metabolism of glucuronate-containing carbohydrates and drugs. Hundreds of putative bacterial GUS enzymes have been identified by metagenomic analysis of the human gut microbiome, but less than 10% have characterized structures and functions. Here we describe a set of unique gut microbial GUS ...
DOI:
10.1016/j.jmb.2019.01.013

6. Deciphering the evolution characteristics of extracellular microbial products from autotrophic and mixotrophic anammox consortia in response to nitrogen loading variations

Author:
Zhang, Zheng-Zhe; Cheng, Ya-Fei; Liu, Ying-Yi; Zhang, Qian; Zhu, Bing-Qian; Jin, Ren-Cun
Source:
Environment international 2019 v.124 pp. 501-510
ISSN:
0160-4120
Subject:
carbohydrate metabolism,   etc   ; anaerobic ammonium oxidation; bioreactors; chemical oxygen demand; factor analysis; fluorescence emission spectroscopy; genes; monitoring; nitrifying bacteria; nitrogen; polysaccharides; total nitrogen; wastewater treatment;     Show all 13 Subjects
Abstract:
... Extracellular microbial products (EMP) in biological wastewater treatment systems vary with operational conditions and in turn indicate the metabolic status of functional bacteria. In this study, the response of EMP from autotrophic and mixotrophic anammox consortia (AAC and MAC) to the variation of total nitrogen loading rates (TNLR) were investigated as well as their correlations with the commun ...
DOI:
10.1016/j.envint.2018.12.034

7. Does a ghrelin stimulus during zebrafish embryonic stage modulate its performance on the long-term?

Author:
Navarro-Guillén, Carmen; Dias, Jorge; Rocha, Filipa; Castanheira, M.F.; Martins, Catarina I.M.; Laizé, Vincent; Gavaia, Paulo J.; Engrola, Sofia
Source:
Comparative biochemistry and physiology 2019 v.228 pp. 1-8
ISSN:
1095-6433
Subject:
carbohydrate metabolism,   etc   ; Danio rerio; biochemical pathways; digestive system; eggs; energy balance; food intake; foraging; gene expression; ghrelin; larvae; ligands; lipids; locomotion; messenger RNA; protein metabolism; somatotropin; swimming;     Show all 18 Subjects
Abstract:
... Metabolic programming refers to the induction, deletion, or impaired development of a somatic structure or “setting” of a physiological system by an early life stimulus operated at a critical period during development. Ghrelin is the only known orexigenic gut hormone, is an acylated peptide that acts as an endogenous ligand specific for growth-hormone secretagogue-receptor. The aim of the present ...
DOI:
10.1016/j.cbpa.2018.10.019

8. Effects of individual and combined zinc oxide nanoparticle, norfloxacin, and sulfamethazine contamination on sludge anaerobic digestion

Author:
Zhao, Lin; Ji, Yi; Sun, Peizhe; Deng, Jinghui; Wang, Hongyang; Yang, Yongkui
Source:
Bioresource technology 2019 v.273 pp. 454-461
ISSN:
0960-8524
Subject:
carbohydrate metabolism,   etc   ; Archaea; anaerobic digestion; antibiotics; fermentation; hydrolysis; methane production; nanoparticles; norfloxacin; pollution; pollution control; risk; sludge; sulfamethazine; toxicity; zinc oxide;     Show all 16 Subjects
Abstract:
... This work investigated the individual and combined effects of zinc oxide, norfloxacin, and sulfamethazine on sludge anaerobic digestion-associated methane production, protein and carbohydrate metabolism, and microbial diversity. Norfloxacin and sulfamethazine (500 mg/kg) did not inhibit methane production, but inhibited its production rate. Zinc oxide nanoparticles with antibiotics inhibited hydro ...
DOI:
10.1016/j.biortech.2018.11.049

9. Global transcriptomic response of Listeria monocytogenes during growth on cantaloupe slices

Author:
Kang, Jihun; Burall, Laurel; Mammel, Mark K.; Datta, Atin R.
Source:
Food microbiology 2019 v.77 pp. 192-201
ISSN:
0740-0020
Subject:
carbohydrate metabolism,   etc   ; Listeria monocytogenes; biosynthesis; cantaloupes; foods; gastric juice; gene expression regulation; iron; isoleucine; leucine; messenger RNA; microarray technology; operon; pathogens; refrigeration; transcription (genetics); transcriptomics; valine; virulence;     Show all 19 Subjects
Abstract:
... Understanding a pathogen's response to food environments is imperative to develop effective control strategies as well as to elucidate the impact of foods on virulence potential. The purpose of this study was to assess transcriptional response of Listeria monocytogenes after growth in cantaloupe, as well as its impact on survival in synthetic gastric fluid (SGF). The transcriptional profiles of L. ...
DOI:
10.1016/j.fm.2018.09.012

10. Target of rapamycin‐signaling modulates starch accumulation via glycogenin phosphorylation status in the unicellular red alga Cyanidioschyzon merolae

Author:
Pancha, Imran; Shima, Hiroki; Higashitani, Nahoko; Igarashi, Kazuhiko; Higashitani, Atsushi; Tanaka, Kan; Imamura, Sousuke
Source:
Theplant journal 2019 v.97 no.3 pp. 485-499
ISSN:
0960-7412
Subject:
carbohydrate metabolism,   etc   ; Rhodophyta; aspartic acid; dimethyl sulfoxide; drugs; eukaryotic cells; genes; glycogen; liquid chromatography; phosphoproteome; phosphorylation; proteins; rapamycin; signal transduction; starch; tandem mass spectrometry; transcriptomics; yeasts;     Show all 18 Subjects
Abstract:
... The target of rapamycin (TOR) signaling pathway is involved in starch accumulation in various eukaryotic organisms; however, the molecular mechanism behind this phenomenon in eukaryotes has not been elucidated. We report a regulatory mechanism of starch accumulation by TOR in the unicellular red alga, Cyanidioschyzon merolae. The starch content in C. merolae after TOR‐inactivation by rapamycin, a ...
DOI:
10.1111/tpj.14136

11. Metabolomics study of the therapeutic mechanism of a Chinese herbal formula on collagen-induced arthritis mice

Author:
Jin, Zhen; Zhang, Ji-da; Wu, Xin; Cao, Gang
Source:
RSC advances 2019 v.9 no.7 pp. 3716-3725
ISSN:
2046-2069
Subject:
carbohydrate metabolism,   etc   ; Oriental traditional medicine; arachidonic acid; biochemical pathways; biomarkers; lipid metabolism; mechanism of action; metabolites; metabolomics; mice; multivariate analysis; prediction; rheumatoid arthritis; therapeutics; thiamin;     Show all 15 Subjects
Abstract:
... Wenjinghuoluo (WJHL) prescription, the typical rheumatoid arthritis (RA) treatment compound in traditional Chinese medicine, shows favorable efficacy. The precise mechanism of WJHL on RA therapy is yet to be elucidated. This study aimed to determine the metabolic biomarkers in the early onset of RA and evaluate the regulation effect of WJHL on metabolite levels. Multivariate statistical analysis i ...
DOI:
10.1039/c8ra05528a

12. Analysis of proteomic responses of freeze-dried Oenococcus oeni to access the molecular mechanism of acid acclimation on cell freeze-drying resistance

Author:
Yang, Kun; Zhu, Yang; Qi, Yiman; Zhang, Tingjing; Liu, Miaomiao; Zhang, Jie; Wei, Xinyuan; Fan, Mingtao; Zhang, Guoqiang
Source:
Food chemistry 2019
ISSN:
0308-8146
Subject:
carbohydrate metabolism,   etc   ; Oenococcus oeni; acclimation; adenosine triphosphate; arginine deiminase; biosynthesis; cell walls; freeze drying; malolactic fermentation; proteins; proteomics; secretion; stress response; sugars; viability; wine quality;     Show all 16 Subjects
Abstract:
... Malolactic fermentation (MLF), usually induced by Oenococcus oeni (O. oeni), is an important process to improve wine quality. Acid acclimation has been proven to be useful for enhancing the viability of lyophilized O. oeni. To explain the involved mechanisms, cell integrity, morphology and protein patterns of lyophilized O. oeni SD-2a were investigated with acid acclimation. After lyophilization, ...
DOI:
10.1016/j.foodchem.2019.01.120

13. DNA methylation footprints during soybean domestication and improvement

Author:
Shen, Yanting; Zhang, Jixiang; Liu, Yucheng; Liu, Shulin; Liu, Zhi; Duan, Zongbiao; Wang, Zheng; Zhu, Baoge; Guo, Ya-Long; Tian, Zhixi
Source:
Genome biology 2018 v.19 no.1 pp. 128
ISSN:
1474-760X
Subject:
carbohydrate metabolism,   etc   ; DNA methylation; bisulfites; cultivars; domestication; epigenetics; genes; genetic variation; landraces; sequence analysis; soybeans;     Show all 11 Subjects
Abstract:
... BACKGROUND: In addition to genetic variation, epigenetic variation plays an important role in determining various biological processes. The importance of natural genetic variation to crop domestication and improvement has been widely investigated. However, the contribution of epigenetic variation in crop domestication at population level has rarely been explored. RESULTS: To understand the impact ...
DOI:
10.1186/s13059-018-1516-z

14. Impact of anti-acidification microbial consortium on carbohydrate metabolism of key microbes during food waste composting

Author:
Song, Caihong; Li, Mingxiao; Qi, Hui; Zhang, Yali; Liu, Dongming; Xia, Xunfeng; Pan, Hongwei; Xi, Beidou
Source:
Bioresource technology 2018 v.259 pp. 1-9
ISSN:
0960-8524
Subject:
carbohydrate metabolism,   etc   ; biochemical pathways; biotransformation; cellulose; composting; enzymes; food waste; hemicellulose; inoculum; lignin; propionic acid;     Show all 11 Subjects
Abstract:
... This study investigated the effect of anti-acidification microbial consortium (AAMC), which act synergistically for rapid bioconversion of organic acids on carbohydrate metabolism of key microbes in the course of food waste (FW) composting by metaproteomics. AAMC was inoculated to the composting mass and compared with treatment with alkaline compounds and the control without any amendment. Inocula ...
DOI:
10.1016/j.biortech.2018.03.022

15. Glycan Utilization and Cross-Feeding Activities by Bifidobacteria

Author:
Turroni, Francesca; Milani, Christian; Duranti, Sabrina; Mahony, Jennifer; van Sinderen, Douwe; Ventura, Marco
Source:
Trends in microbiology 2018 v.26 no.4 pp. 339-350
ISSN:
0966-842X
Subject:
carbohydrate metabolism,   etc   ; Bifidobacterium; bacteria; chromosomes; digestive system; genes; mammals; polysaccharides; social behavior;     Show all 9 Subjects
Abstract:
... Bifidobacteria represent one of the first colonizers of the mammalian gut, where such colonization is facilitated by their saccharolytic capabilities. Genomic analyses of bifidobacteria have revealed intriguing genetic strategies employed by these bacteria to access a variety of dietary and host-produced glycans. Bifidobacterial genome evolution therefore represents a fascinating example of how th ...
DOI:
10.1016/j.tim.2017.10.001

16. The role of receptor-like kinases in regulating plant male reproduction

Author:
Cai, Wenguo; Zhang, Dabing
Source:
Plant reproduction 2018 v.31 no.1 pp. 77-87
ISSN:
2194-7953
Subject:
carbohydrate metabolism,   etc   ; cell communication; ligands; males; phosphotransferases (kinases); plant growth; reproduction;     Show all 7 Subjects
Abstract:
... KEY MESSAGE: RLKs in anther development. The cell-to-cell communication is essential for specifying different cell types during plant growth, development and adaption to the ever-changing environment. Plant male reproduction, in particular, requires the exquisitely synchronized development of different cell layers within the male tissue, the anther. Receptor-like kinases (RLKs) belong to a large g ...
DOI:
10.1007/s00497-018-0332-7

17. Improvement in Submergence Tolerance of Cherry Through Regulation of Carbohydrate Metabolism and Plant Growth by PsERF and PsCIPK

Author:
Sheng, Lixia; Meng, Xiangyi; Wang, Meng; Zang, Shu; Feng, Liguo
Source:
Applied biochemistry and biotechnology 2018 v.184 no.1 pp. 63-79
ISSN:
0273-2289
Subject:
carbohydrate metabolism,   etc   ; Prunus pseudocerasus; Prunus serrulata; cherries; flooding tolerance; genes; genetic engineering; germplasm; plant growth; submergence;     Show all 10 Subjects
Abstract:
... Cherry is an important fruit tree with delicious taste and high economic value, which have been planted worldwide. However, this species cannot withstand the presence of excessive amount of water; submergence injury sometimes occurs during cultivation of cherry and results in severe economic losses. By using a submergence-tolerant germplasm Prunus serrulata “Yimeng” and a submergence-sensitive ger ...
DOI:
10.1007/s12010-017-2530-4

18. First RNA-seq approach to study fruit set and parthenocarpy in zucchini (Cucurbita pepo L.)

Author:
Pomares-Viciana, Teresa; Del Río-Celestino, Mercedes; Román, Belén; Die, Jose; Pico, Belén; Gómez, Pedro
Source:
BMC plant biology 2019 v.19 no.1 pp. 61
ISSN:
1471-2229
Subject:
carbohydrate metabolism,   etc   ; Cucurbita pepo subsp. pepo; auxins; breeding programs; cell cycle; crops; cultivars; environmental factors; ethylene; gene expression regulation; genes; gibberellins; high-throughput nucleotide sequencing; hormones; parthenocarpy; pollination; transcriptome; transcriptomics; zucchini;     Show all 19 Subjects
Abstract:
... BACKGROUND: Zucchini fruit set can be limited due to unfavourable environmental conditions in off-seasons crops that caused ineffective pollination/fertilization. Parthenocarpy, the natural or artificial fruit development without fertilization, has been recognized as an important trait to avoid this problem, and is related to auxin signalling. Nevertheless, differences found in transcriptome analy ...
DOI:
10.1186/s12870-019-1632-2

19. Effect of soil horizon stratigraphy on the microbial ecology of alpine paleosols

Author:
Young, Jonathan M.; Skvortsov, Timofey; Kelleher, Brian P.; Mahaney, William C.; Somelar, Peeter; Allen, Christopher C.R.
Source:
The Science of the total environment 2019 v.657 pp. 1183-1193
ISSN:
0048-9697
Subject:
carbohydrate metabolism,   etc   ; Bacilli; bacterial communities; beta-Proteobacteria; carbohydrates; carbon dioxide; carbon dioxide fixation; community structure; fermentation; genes; high-throughput nucleotide sequencing; microbiology; multivariate analysis; nitrogen metabolism; paleosolic soil types; soil depth; soil horizons; species diversity; stratigraphy; taxonomy; weathering;     Show all 21 Subjects
Abstract:
... There is remarkable potential for research at the interface between the earth sciences and environmental microbiology that may lead to advances in our understanding of the role of bacterial communities in the surface or subsurface environment of our planet. One mainstay of sedimentary classification is the concept of differential soil and/or paleosol horizons being the result of primarily physical ...
DOI:
10.1016/j.scitotenv.2018.11.442

20. Comparative transcriptomics reveals potential genes involved in the vegetative growth of Morchella importuna

Author:
Liu, Wei; Cai, Yingli; He, Peixin; Chen, Lianfu; Bian, Yinbing
Source:
3 Biotech 2019 v.9 no.3 pp. 81
ISSN:
2190-572X
Subject:
carbohydrate metabolism,   etc   ; Morchella; beta-galactosidase; caprolactam; catalytic activity; energy metabolism; gene expression; genes; medicinal fungi; morphogenesis; mycelium; open reading frames; polysaccharides; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; sclerotia; transcription (genetics); transcriptome; transcriptomics; vegetative growth;     Show all 20 Subjects
Abstract:
... True morels (Morchella spp.) are edible, medicinal mushrooms which have recently been artificially cultivated in China but stable production remains a problem. Here, we describe complete and comprehensive transcriptome of Morchella importuna at the stages of vegetative mycelium (VM), initial sclerotium (IS) and mature sclerotium (MS) by deep transcriptional sequencing and de novo assembly for the ...
DOI:
10.1007/s13205-019-1614-y