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1. Bilayer biodegradable films prepared by co-extrusion film blowing: Mechanical performance, release kinetics of an antimicrobial agent and hydrolytic degradation

Author:
Scaffaro, Roberto; Maio, Andrea; Gulino, Fortunato E.; Di Salvo, Claudio; Arcarisi, Alessia
Source:
Composites 2020 v.132 pp. 105836
ISSN:
1359-835X
Subject:
carvacrol,   etc   ; adhesion; anti-infective agents; biodegradability; composite materials; mechanical testing; nanoclays; polylactic acid; volatilization;     Show all 9 Subjects
Abstract:
... Bilayer biodegradable, eco-friendly films were prepared by co-extrusion film blowing, coupling polylactic acid (PLA) and Bio-flex ® (BIO). Furthermore, in the PLA layer, carvacrol (CRV) was added as a natural antimicrobial additive, whereas a nanoclay (D72T) was integrated to protect CRV from volatilization and to modulate release. The materials were analyzed by morphological, chemical-physical, m ...
DOI:
10.1016/j.compositesa.2020.105836

2. Structure–Odor Activity Studies on Derivatives of Aromatic and Oxygenated Monoterpenoids Synthesized by Modifying p-Cymene

Author:
Schreiner, Linda; Bauer, Johannes; Ortner, Eva; Buettner, Andrea
Source:
Journal of natural products 2020 v.83 no.4 pp. 834-842
ISSN:
1520-6025
Subject:
carvacrol,   etc   ; air; foods; monoterpenoids; odor compounds; odors; oregano; p-cymene; quinones; smell; thyme; thymol;     Show all 12 Subjects
Abstract:
... Thymoquinone was recently reported as having a unique pencil-like odor and being the impact compound for the cedar-like and cedar wood-based product smell such as pencils. The compounds thymol and carvacrol are structurally related odorants commonly found in plants and foods such as thyme and oregano, also having a significant contribution to their overall aroma. However, a systematic elucidation ...
DOI:
10.1021/acs.jnatprod.9b00339

3. Mucus-Inspired Supramolecular Adhesives with Oil-Regulated Molecular Configurations and Long-Lasting Antibacterial Properties

Author:
He, Wenqing; Wang, Zhaoyue; Hou, Changshun; Huang, Xin; Yi, Bo; Yang, Yuhe; Zheng, Wenrui; Zhao, Xin; Yao, Xi
Source:
ACS applied materials & interfaces 2020 v.12 no.14 pp. 16877-16886
ISSN:
1944-8252
Subject:
carvacrol,   etc   ; adhesives; antibacterial properties; buildings; coatings; crosslinking; fabrics; food storage; hydrogen bonding; mechanics; models; oils; packaging;     Show all 13 Subjects
Abstract:
... Inspired by mucus, which provides an ideal supramolecular model and whose fluid-like (viscous) and solid-like (elastic) behaviors can be adjusted to meet different physiological requirements, we report oil-regulated supramolecular adhesives by the co-assembly of polyurea oligomers and carvacrol oils. The adhesive is crosslinked by weak but abundant hydrogen bonds, which can be regulated by the inc ...
DOI:
10.1021/acsami.0c00531

4. Multiscale Structural Characterization of Biobased Diallyl–Eugenol Polymer Networks

Author:
Rios de Anda, Agustín; Sotta, Paul; Modjinou, Tina; Langlois, Valérie; Versace, Davy-Louis; Renard, Estelle
Source:
Macromolecules 2020 v.53 no.6 pp. 2187-2197
ISSN:
1520-5835
Subject:
carvacrol,   etc   ; biopolymers; crosslinking; dielectric spectroscopy; nuclear magnetic resonance spectroscopy; phenol; plasticizers; separation; structure-activity relationships;     Show all 9 Subjects
Abstract:
... Biosourced eugenol-based polymer networks have a potential functionality for antibacterial coating applications. The presence of carvacrol, a phenol compound, improves these properties. However, the relationship between the network structure and the macroscopic thermomechanical behavior is not known for these biopolymers. Thus, this work details a robust study of this relationship through a multis ...
DOI:
10.1021/acs.macromol.9b02280

5. Biodegradability and disintegration of multilayer starch films with electrospun PCL fibres encapsulating carvacrol

Author:
Tampau, Alina; González-Martínez, Chelo; Chiralt, Amparo
Source:
Polymer degradation and stability 2020 v.173 pp. 109100
ISSN:
0141-3910
Subject:
carvacrol,   etc   ; biodegradability; biodegradation; carbon dioxide; composting; composts; encapsulation; inoculum; lactones; starch; thermogravimetry; thermoplastics;     Show all 12 Subjects
Abstract:
... The biodegradation and disintegration of thermoplastic starch multilayers containing carvacrol(CA)-loaded poly-(ε-caprolactone) electrospun mats were evaluated under thermophilic composting conditions for 45 and 84 days, respectively, and compared with non-loaded carvacrol films and pure starch films. Sample mass loss, thermogravimetric and visual analyses were performed throughout the disintegrat ...
DOI:
10.1016/j.polymdegradstab.2020.109100

6. Thymol and carvacrol in nanoliposomes: Characterization and a comparison with free counterparts against planktonic and glass-adhered Salmonella

Author:
Heckler, Caroline; Marques Maders Silva, Caroline; Ayres Cacciatore, Fabiola; Daroit, Daniel Joner; da Silva Malheiros, Patrícia
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2020 v.127 pp. 109382
ISSN:
0023-6438
Subject:
carvacrol,   etc   ; Salmonella; anti-infective agents; bacterial adhesion; disinfection; encapsulation; food processing; foods; glass; minimum inhibitory concentration; plankton; thymol; zeta potential;     Show all 13 Subjects
Abstract:
... Nanoliposome-encapsulated and free thymol, carvacrol, and thymol/carvacrol (1:1) were assessed as antimicrobials against a Salmonella pool. Liposome-encapsulated thymol (TL), carvacrol (CL) and thymol/carvacrol (TCL) presented 230–270 nm diameter, satisfactory polydispersity (0.24–0.31), zeta potential of approximately −30 mV and high encapsulation efficiencies (~99%), remaining stable during 28 d ...
DOI:
10.1016/j.lwt.2020.109382

7. Polylactic acid–based materials encapsulating carvacrol obtained by solvent casting and electrospinning

Author:
Tampau, Alina; González‐Martínez, Chelo; Chiralt, Amparo
Source:
Journal of food science 2020 v.85 no.4 pp. 1177-1185
ISSN:
0022-1147
Subject:
carvacrol,   etc   ; antioxidants; differential scanning calorimetry; dimethyl sulfoxide; encapsulation; ethyl acetate; foods; packaging; polylactic acid; scanning electron microscopy; solvents; thermogravimetry;     Show all 12 Subjects
Abstract:
... Polylactic acid (PLA) dissolved (15 wt.%) in ethyl acetate (EtAc): dimethyl sulfoxide (DMSO) binary systems (0:1; 1:3, and 2:3 v/v) was used as carrier to obtain carvacrol (CA)‐loaded (20 wt.% with respect to PLA) matrices by electrospinning, in comparison with solvent casting. Field emission scanning electron microscopy (FESEM) observations showed that CA‐loaded electrospun fibers were thinner th ...
DOI:
10.1111/1750-3841.15094

8. In vitro scolicidal activity of Thymus capitatus Hoff. et Link. essential oil on Echinococcus granulosus protoscoleces

Author:
Hizem, Amani; M’rad, Selim; Oudni-M’rad, Myriam; Mezhoud, Habib; Ben Jannet, Hichem; Flamini, Guido; Ghedira, Kamel; Babba, Hamouda
Source:
TheJournal of essential oil research 2020 v.32 no.2 pp. 178-185
ISSN:
2163-8152
Subject:
carvacrol,   etc   ; Echinococcus granulosus; Thymbra capitata; adverse effects; echinococcosis; eosin; essential oils; gas chromatography-mass spectrometry; protoscoleces; risk; staining; surgery; viability;     Show all 13 Subjects
Abstract:
... Cystic echinococcosis remains a serious public health problem worldwide. Surgery is considered as the first option of treatment. Various investigations were carried out to find a convenient scolicidal agent for reducing the risk of post-surgical recurrence of the disease but most of them are associated with adverse side effects. The present study aimed to evaluate the in vitro scolicidal activity ...
DOI:
10.1080/10412905.2019.1711212

9. Temperature‐sensitive polyurethane (TSPU) film incorporated with carvacrol and cinnamyl aldehyde: antimicrobial activity, sustained release kinetics and potential use as food packaging for Cantonese‐style moon cake

Author:
Dong, Hao; He, Jiapeng; Xiao, Kaijun; Li, Chao
Source:
International journal of food science & technology 2020 v.55 no.1 pp. 293-302
ISSN:
0950-5423
Subject:
carvacrol,   etc   ; aldehydes; antimicrobial properties; cakes; equations; food packaging; lipid peroxidation; microbial growth; packaging films; polyethylene; polyurethanes; shelf life; temperature;     Show all 13 Subjects
Abstract:
... Temperature‐sensitive polyurethane (TSPU) films incorporated with carvacrol and cinnamyl aldehyde were prepared for the potential use of food packaging. The antimicrobial properties and sustained release kinetics of carvacrol and cinnamyl aldehyde in TSPU film were investigated. Results indicated that cinnamyl aldehyde and carvacrol had favourable antimicrobial properties at relatively low additio ...
DOI:
10.1111/ijfs.14276

10. Antifungal activity of phenolic monoterpenes and structure-related compounds against plant pathogenic fungi

Author:
Wang, Kaibo; Jiang, Shanshan; Pu, Te; Fan, Liming; Su, Fawu; Ye, Min
Source:
Natural product research 2019 v.33 no.10 pp. 1423-1430
ISSN:
1478-6427
Subject:
carvacrol,   etc   ; antifungal properties; fungicides; monoterpenoids; mycelium; plant pathogenic fungi; thymol;     Show all 7 Subjects
Abstract:
... The aim of this work is to explore the possibility of using the phenolic monoterpenes (PMs) as leading compounds with antifungal activity against plant disease. The in vitro antifungal activities of carvacrol and thymol against seven kinds of plant pathogenic fungi were evaluated on mycelium growth rate method, and the results showed that carvacrol and thymol exhibited broad spectrum antifungal ac ...
DOI:
10.1080/14786419.2017.1419232

11. Assessment of different antimicrobials to inhibit the growth of Zygosaccharomyces rouxii cocktail in concentrated apple juice

Author:
Wang, Huxuan; Sun, Hongmin
Source:
Food microbiology 2020 v.91 pp. 103549
ISSN:
0740-0020
Subject:
carvacrol,   etc   ; Zygosaccharomyces rouxii; anti-infective agents; antimicrobial properties; apple juice; biopreservatives; brix; equations; essential oils; grape must; honey; juice industry; mathematical models; spoilage; thymol; yeasts;     Show all 16 Subjects
Abstract:
... Zygosaccharomyces rouxii represents the main spoilage cause of concentrated apple juice, leading to waste of products or recalls. Essential oils components derived from plants have been found to present antimicrobial activities against various microbes. However, few work has been reported about their antimicrobial activities against Z. rouxii in concentrated apple juice. In this work, reparameteri ...
DOI:
10.1016/j.fm.2020.103549

12. Interactions between fish isolates Pseudomonas fluorescens and Staphylococcus aureus in dual-species biofilms and sensitivity to carvacrol

Author:
Wang, Yaying; Hong, Xiaoli; Liu, Jingcong; Zhu, Junli; Chen, Jinru
Source:
Food microbiology 2020 v.91 pp. 103506
ISSN:
0740-0020
Subject:
carvacrol,   etc   ; Pseudomonas fluorescens; Staphylococcus aureus; biofilm; cell viability; coculture; financial economics; fish; food contamination; inoculum; juices; plankton; quorum sensing; secretion; spoilage;     Show all 15 Subjects
Abstract:
... Biofilm formation is a frequent source of contamination of food products, which results in significant economic losses through microbial spoilage and poses serious health concerns. Little is known about the fate of Staphylococcus aureus in the dual-species biofilms with Pseudomonas fluorescens an important spoiler commonly found in aquatic products. This study evaluates the interactions between mo ...
DOI:
10.1016/j.fm.2020.103506

13. Chemical composition and biological activities of the essential oil from Pulicaria undulata (L.) C. A. Mey. growing wild in Egypt

Author:
Mustafa, Ahmed M.; Eldahmy, Samih I.; Caprioli, Giovanni; Bramucci, Massimo; Quassinti, Luana; Lupidi, Giulio; Beghelli, Daniela; Vittori, Sauro; Maggi, Filippo
Source:
Natural product research 2020 v.34 no.16 pp. 2358-2362
ISSN:
1478-6427
Subject:
carvacrol,   etc   ; 2,2-diphenyl-1-picrylhydrazyl; Pulicaria undulata; antioxidant activity; cell lines; chemical composition; cytotoxicity; essential oils; gas chromatography-mass spectrometry; inhibitory concentration 50; monoterpenoids; oils; traditional medicine; Egypt;     Show all 14 Subjects
Abstract:
... Pulicaria undulata is used as a traditional herbal remedy in Egypt. We used gas chromatography-mass spectrometry for analysis of essential oil of this plant growing wild in Egypt and 64 compounds were identified. The oil was rich in oxygenated monoterpenes (64.0%) and aromatic derivatives (18.8%). The major components were carvacrol (46.5%), xanthoxylin (18.1%) and carvotanacetone (8.7%). The oil ...
DOI:
10.1080/14786419.2018.1534107

14. Carvacrol release from PLA to a model food emulsion: Impact of oil droplet size

Author:
Wang, Li; Dekker, Matthijs; Heising, Jenneke; Fogliano, Vincenzo; Berton-Carabin, Claire C.
Source:
Food control 2020 v.114 pp. 107247
ISSN:
0956-7135
Subject:
carvacrol,   etc   ; active food packaging; antimicrobial properties; bacterial growth; droplet size; droplets; emulsions; food matrix; model food systems; oils; polylactic acid; whey protein isolate;     Show all 12 Subjects
Abstract:
... The effect of food structure on the release of a volatile antimicrobial from an active packaging (AP) was investigated by measuring the migration of carvacrol from a polylactic acid (PLA) film to a model food system, namely, an oil-in-water (O/W) emulsion. We aimed to understand the influence of the oil droplet size on the kinetics of carvacrol migration from the PLA film to the emulsions, on its ...
DOI:
10.1016/j.foodcont.2020.107247

15. Synergistic interaction between carvacrol and Bacillus thuringiensis crystalline proteins against Cydia pomonella and Spodoptera exigua

Author:
Konecka, Edyta; Kaznowski, Adam; Grzesiek, Weronika; Nowicki, Patryk; Czarniewska, Elżbieta; Baranek, Jakub
Source:
BioControl 2020 v.65 no.4 pp. 447-460
ISSN:
1386-6141
Subject:
carvacrol,   etc   ; Bacillus thuringiensis; Cydia pomonella; Spodoptera exigua; bacterial toxins; biological control; crops; hemocytes; immune system; insect larvae; insect pests; mortality; oral exposure; proteins; synergism; toxicity;     Show all 16 Subjects
Abstract:
... The aim of our study was to determine the usefulness of mixtures of carvacrol and Bacillus thuringiensis crystalline proteins Cry against pests of two different species: Cydia pomonella L. (Lepidoptera: Tortricidae) and Spodoptera exigua Hübner (Lepidoptera: Noctuidae). The novelty of our work lies in showing the interactions between carvacrol and bacterial toxins against insect pests. Moreover, w ...
DOI:
10.1007/s10526-020-10011-4

16. Fat content and storage conditions are key factors on the partitioning and activity of carvacrol in antimicrobial packaging

Author:
Wang, Li; Heising, Jenneke; Fogliano, Vincenzo; Dekker, Matthijs
Source:
Food packaging and shelf life 2020 v.24 pp. 100500
ISSN:
2214-2894
Subject:
carvacrol,   etc   ; absorption; antimicrobial packaging; antimicrobial properties; food matrix; food packaging; ground beef; headspace analysis; humidity; lipid content; mass transfer; polylactic acid; shelf life; storage temperature; volatile compounds;     Show all 15 Subjects
Abstract:
... The ability of carvacrol loaded polylactic acid (PLA) films to improve ground beef preservation was assessed. The mass transfer processes of carvacrol partitioning in a food packaging system between the PLA film, headspace and food product was studied. Carvacrol release was studied on packed ground beef having a fat content of 5 or 12 % at a temperature between 5 and 30 °C and a humidity between 4 ...
DOI:
10.1016/j.fpsl.2020.100500

17. Combination of mild heat and plant essential oil constituents to inactivate resistant variants of Escherichia coli in buffer and in coconut water

Author:
Gayán, Elisa; Geens, Elise; Berdejo, Daniel; García-Gonzalo, Diego; Pagán, Rafael; Aertsen, Abram; Michiels, Chris W.
Source:
Food microbiology 2020 v.87 pp. 103388
ISSN:
0740-0020
Subject:
carvacrol,   etc   ; Escherichia coli O157; anti-infective agents; bacteria; citral; coconut water; essential oils; heat; heat inactivation; heat tolerance; minimally processed foods; mutants; preservatives; processing technology; synergism; temperature;     Show all 16 Subjects
Abstract:
... The growing demand for minimally processed foods with clean labels has stimulated research into mild processing methods and natural antimicrobials to replace intensive heating and conventional preservatives, respectively. However, we have previously demonstrated that repetitive exposure of some bacteria to mild heat or subinhibitory concentrations of essential oil constituents (EOCs) may induce th ...
DOI:
10.1016/j.fm.2019.103388

18. Essential oils, chemical constituents, antioxidant, antibacterial and in vitro cytotoxic activity of different Thymus species and Zataria multiflora collected from Iran

Author:
Golkar, Pooran; Mosavat, Nima; Jalali, Seyed Amir Hossein
Source:
South African journal of botany 2020 v.130 pp. 250-258
ISSN:
0254-6299
Subject:
carvacrol,   etc   ; Thymus daenensis; Thymus kotschyanus; Thymus vulgaris; Zataria multiflora; anthocyanins; antineoplastic activity; antioxidant activity; antioxidants; bioactive compounds; cytotoxicity; essential oils; flavonols; industry; ingredients; thymol; Iran;     Show all 17 Subjects
Abstract:
... The present study evaluated the essential oil (EO) compositions, total phenolics (TPC), total flavonoids (TFD), total flavonols (TFL), anthocyanin (Ant) and biological activities of three Thymus population (T. daenensis Celak; T. vulgaris L. and T. kotschyanus Celak and Zataria multiflora Boiss collected from diverse geographical locations in Iran. Carvacrol (4.99 - 46.22%) and thymol (14.8 - 70.1 ...
DOI:
10.1016/j.sajb.2019.12.005

19. Phytochemical- and Cyclodextrin-Based Pickering Emulsions: Natural Potentiators of Antibacterial, Antifungal, and Antibiofilm Activity

Author:
Leclercq, Loïc; Tessier, Jérémie; Douyère, Grégory; Nardello-Rataj, Véronique; Schmitzer, Andreea R.
Source:
Langmuir 2020 v.36 no.16 pp. 4317-4323
ISSN:
1520-5827
Subject:
carvacrol,   etc   ; Candida albicans; Escherichia coli; Staphylococcus aureus; antimicrobial properties; bacteria; beta-cyclodextrin; biofilm; emulsions; enzyme inhibition; enzymes; fungi; membrane permeability; miconazole; nitrates; oils; phytochemicals; reactive oxygen species; synergism;     Show all 19 Subjects
Abstract:
... We present self-assembled Pickering emulsions containing biocidal phytochemical oils (carvacrol and terpinen-4-ol) and β-cyclodextrin able to potentiate the antimicrobial and antibiofilm activity of miconazoctylium bromide. The carvacrol-containing emulsion is 2-fold more sensitive against C. albicans and S. aureus and highly active against E. coli, compared to the commercial cream containing mico ...
DOI:
10.1021/acs.langmuir.0c00314

20. Quantitative Structure–Activity Relationship Modeling and Docking of Monoterpenes with Insecticidal Activity Against Reticulitermes chinensis Snyder and Drosophila melanogaster

Author:
Soares Rodrigues, Gabriela Cristina; dos Santos Maia, Mayara; Muratov, Eugene N.; Scotti, Luciana; Scotti, Marcus Tullius
Source:
Journal of agricultural and food chemistry 2020 v.68 no.16 pp. 4687-4698
ISSN:
1520-5118
Subject:
carvacrol,   etc   ; Drosophila melanogaster; Reticulitermes chinensis; acetates; acetylcholinesterase; active sites; citronellal; computer simulation; insecticidal properties; methiocarb; molecular dynamics; pirimicarb; quantitative structure-activity relationships; simulation models;     Show all 14 Subjects
Abstract:
... The goal of this study was to perform in silico identification of bioinsecticidal potential of 42 monoterpenes against Drosophila melanogaster and Reticulitermes chinensis Snyder. Quantitative structure–activity relationship (QSAR) modeling was performed for both organisms, while docking and molecular dynamics were used only for Drosophila melanogaster. Neryl acetate has the lowest interaction ene ...
DOI:
10.1021/acs.jafc.0c00272