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1. Unraveling the mechanism of the synergistic antimicrobial effect of cineole and carvacrol on Escherichia coli O157:H7 inhibition and its application on fresh-cut cucumbers

Author:
Keren Agyekumwaa Addo; Hui Li; Yigang Yu; Xinglong Xiao
Source:
Food control 2023 v.144 pp. 109339
ISSN:
0956-7135
Subject:
carvacrol,   etc   ; DNA; Escherichia coli O157; Shiga toxin; antimicrobial properties; bacteria; biofilm; cineole; exopolysaccharides; flagellum; food safety; fresh produce; genes; intimin; mechanism of action; quorum sensing; sanitizers; transcription (genetics); virulence;     Show all 19 Subjects
Abstract:
... The objective of this study was to evaluate the mechanism of the synergistic antimicrobial effect of cineole (CN) and carvacrol (CR) on E. coli and its application on fresh-cut cucumbers. Herein, the CN/CR synergy could effectively inhibit E. coli by destroying its bacterial cell structure and causing the leakage of intracellular organic matters. For the first time, CN/CR synergy interaction on E. ...
DOI:
10.1016/j.foodcont.2022.109339

2. Second-order electrochemical data generation to quantify carvacrol in oregano essential oils

Author:
Gastón Darío Pierini; Santiago Andrés Bortolato; Sebastian Noel Robledo; Mirta Raquel Alcaraz; Héctor Fernández; Héctor Casimiro Goicoechea; María Alicia Zon
Source:
Food chemistry 2022 v.368 pp. 130840
ISSN:
0308-8146
Subject:
carvacrol,   etc   ; electrochemistry; food chemistry; oregano; thymol; voltammetry;     Show all 6 Subjects
Abstract:
... A novel analytical method using voltammetric second-order modeling based on multivariate curve resolution-alternating least-square (MCR-ALS) is presented for the first time for the quantitation of carvacrol (CAR) in oregano essential oils (OEO). The second-order cyclic voltammetry data were generated on the basis that CAR shows a diffusional system. Thus, the scan rate (v) was used as a second ins ...
DOI:
10.1016/j.foodchem.2021.130840

3. Development of sodium alginate-based antioxidant and antibacterial bioactive films added with IRMOF-3/Carvacrol

Author:
Haoyue Ning; Lixin Lu; Jing Xu; Lijing Lu; Liao Pan; Zidong Lin
Source:
Carbohydrate polymers 2022 v.292 pp. 119682
ISSN:
0144-8617
Subject:
carvacrol,   etc   ; antioxidants; hydrophobicity; pork; sodium; sodium alginate; thermal stability; water vapor;     Show all 8 Subjects
Abstract:
... The purpose of this study was to compare the effects of different concentrations of the amine-functionalized isoreticular metal-organic framework-3 loaded with carvacrol (IRMOF-3/CA) on the properties of sodium alginate (SA) composite films, thus determining the optimal addition amount and further preparing bioactive packaging film with antibacterial and antioxidant activities. The morphology, str ...
DOI:
10.1016/j.carbpol.2022.119682

4. Antibacterial effect of the combination of terpenoids

Author:
Takayoshi Yamaguchi
Source:
Archives of microbiology 2022 v.204 no.8 pp. 520
ISSN:
0302-8933
Subject:
carvacrol,   etc   ; Enterococcus faecalis; Staphylococcus aureus; antibacterial properties; color; eugenol; flavor; isoprene; nootkatone; thymol;     Show all 10 Subjects
Abstract:
... Terpenoids are natural compounds originating from five-carbon isoprene units. Over 60,000 terpenoid structures have been identified, and they contribute to the flavor, color, growth, and development of plants. There are several reports on various physiological activities of terpenoids, such as antioxidative and anticancer activities. This study revealed that combinations of terpenoids have activit ...
DOI:
10.1007/s00203-022-03142-y

5. Carvacrol Enhances the Antimicrobial Potency of Berberine in Bacillus subtilis

Author:
Basak Atas; Cemile Selin Aksoy; Fatma Gizem Avci; Nihat Alpagu Sayar; Kutlu Ulgen; Elif Ozkirimli; Berna Sariyar Akbulut
Source:
Current microbiology 2022 v.79 no.5 pp. 135
ISSN:
0343-8651
Subject:
carvacrol,   etc   ; Bacillus subtilis; antimicrobial properties; berberine; essential oils; ethidium; microbiology; oregano; permeability; transporters;     Show all 10 Subjects
Abstract:
... The essential oil carvacrol from oregano displays a wide range of biological activities among which is found the inhibition of efflux pumps. Thus, using carvacrol, the current work undertook the effort to potentiate the antimicrobial activity of berberine, a natural product with limited antimicrobial efficacy due to its efflux. Following the selection of concentrations for the combinatorial treatm ...
DOI:
10.1007/s00284-022-02823-7

6. Influence of two different nanomaterials on Aspergillus fumigatus isolated from salted fish

Author:
Nahed Mahmoud Abdel-Aziz; Sayed Alhabaty
Source:
SVU- International Journal of Veterinary Sciences 2022 v.5 no.1 pp. 17-23
ISSN:
2535-1877
Subject:
carvacrol,   etc   ; Aspergillus fumigatus; chitosan; food industry; food safety; fungi; nanoemulsions; salted fish; ultrastructure;     Show all 9 Subjects
Abstract:
... This study detecting Aspergillus fumigatus in salted fish as Feseakh and Moloha that is being sold in Sohag city markets using culture methods and scanning electron microscope (SEM). In addition, study the effect of chitosan nanoparticles (CNP) and carvacrol nanoemulsion (CNE) with five concentrations on the isolated strains of A. fumigatus using well diffusion method (WDM) and SEM. Results showed ...
DOI:
10.21608/SVU.2022.100311.1154

7. Electrospun Starch Nanofibers as a Delivery Carrier for Carvacrol as Anti‐Glioma Agent

Author:
Laura Martins Fonseca; Natalia Pontes Bona; Rosane Lopes Crizel; Nathalia Stark Pedra; Francieli Moro Stefanello; Loong‐Tak Lim; Neftali Lenin Villarreal Carreño; Alvaro Renato Guerra Dias; Elessandra da Rosa Zavareze
Source:
Stärke = 2022 v.74 no.1-2 pp. e2100115
ISSN:
0038-9056
Subject:
carvacrol,   etc   ; antineoplastic activity; astrocytes; cytotoxicity; digestion; glioma; in vitro digestion; nanofibers; rats; starch;     Show all 10 Subjects
Abstract:
... Phenolic compounds are prone to degradation from external deleterious conditions. Thus, a carrier for its delivery can be useful in protecting them and ensuring their optimal release profile. The objective of this study is to produce starch nanofibers as delivery carriers for carvacrol and to evaluate its in‐vitro digestion simulation and anti‐glioma activity. Nanofibers are produced by electrospi ...
DOI:
10.1002/star.202100115

8. Effect of the pH on the thermodynamic stability of inclusion complexes of thymol and carvacrol in β-cyclodextrin in water

Author:
Oscar E. Cedillo-Flores; Norma Rodríguez-Laguna; Adrián Ricardo Hipólito-Nájera; Didier Nivón-Ramírez; Rodolfo Gómez-Balderas; Rosario Moya-Hernández
Source:
Food hydrocolloids 2022 v.124 pp. 107307
ISSN:
0268-005X
Subject:
carvacrol,   etc   ; calorimetry; hydrocolloids; ionization; pH; terpenoids; thermodynamics; thymol; titration; ultraviolet-visible spectroscopy; water solubility;     Show all 11 Subjects
Abstract:
... Thymol and carvacrol are terpenes which have great potential to be used as preservatives in food and antimicrobial agents in medicinal herbs. As they present low water solubility and display acid-basic properties, inclusion in cyclodextrins and pH variations may enhance their properties. Here, the inclusion of thymol and carvacrol in β-cyclodextrin, at neutral and basic pH at 25 °C, is reported. T ...
DOI:
10.1016/j.foodhyd.2021.107307

9. In vitro assessment of the acaricidal activity of a carvacrol shampoo on tick larvae

Author:
AnildesI.P. Sousa; GlayaneJ.S. Castro; Caio P. Tavares; Tássia L. do Vale; Livio M. Costa-Junior; AlexandraM.S. Soares
Source:
Experimental parasitology 2022 v.242 pp. 108364
ISSN:
0014-4894
Subject:
carvacrol,   etc   ; Rhipicephalus sanguineus; acaricidal properties; acaricides; larvae; larvicides; monoterpenoids; mortality; pH; parasitology; therapeutics; ticks;     Show all 12 Subjects
Abstract:
... Ticks are a widely distributed arthropod of veterinary importance. Resistance of ticks to synthetic acaricides has become widespread, warranting the development of new drugs for tick management. Carvacrol is a volatile monoterpene, with promising results against various species of ticks; however, to be used for therapeutic purposes, carvacrol must be included in a formulation that makes its applic ...
DOI:
10.1016/j.exppara.2022.108364

10. Synthesis of a pyrrolidine derivative of a carvotacetone and monoterpenes for anti-methicillin-resistant Staphylococcus aureus and anti-cryptococcal properties

Author:
Veronica M. Masila; Albert J. Ndakala; Jacob O. Midiwo; Robert Byamukama; Rahab W. Kamau; Mallika Kumarihamy; Ilias Muhammad
Source:
Natural product research 2022 v.36 no.9 pp. 2321-2328
ISSN:
1478-6427
Subject:
carvacrol,   etc   ; Cryptococcus neoformans; acetates; methicillin-resistant Staphylococcus aureus; monoterpenoids; pharmaceutical industry; research; spectral analysis;     Show all 8 Subjects
Abstract:
... Monoterpene derivatives are of great biological relevance in the pharmaceutical industry. In the present study, pyrrolidine derivative of a carvotacetone, 3-O-benzylcarvotacetone (1), and selected monoterpenes (3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (3) and cis-piperitol (5)) were prepared to provide (R)-1-(4-(benzyloxy)-5-isopropyl-2-methylcyclohexa-1,3-dien-1-yl)-pyrrolidine (2), 2-isopro ...
DOI:
10.1080/14786419.2020.1833201

11. Octanol–Water Partition Coefficients and Aqueous Solubility Data of Monoterpenoids: Experimental, Modeling, and Environmental Distribution

Author:
Sérgio M. Vilas-Boas; Mariana C. da Costa; João A. P. Coutinho; Olga Ferreira; Simão P. Pinho
Source:
Industrial & engineering chemistry process design and development 2022 v.61 no.8 pp. 3154-3167
ISSN:
1520-5045
Subject:
carvacrol,   etc   ; cineole; eugenol; geraniol; linalool; process design; secondary metabolites; thermodynamic models; thymol; water solubility;     Show all 10 Subjects
Abstract:
... Terpenes and terpenoids encompass one of the most extensive and valuable classes of secondary metabolites. Their ten-carbon-containing oxygenated representatives, monoterpenoids, are the main components of plant essential oils, being widely exploited in the cosmetic, pharmaceutical, and food industrial areas. Due to its widespread use, it is crucial to investigate their environmental distribution. ...
DOI:
10.1021/acs.iecr.1c04196

12. Curcumin or microencapsulated phytogenic blend to replace ionophore and non-ionophore antibiotics in weaned calves: Effects on growth performance and health

Author:
Vitor L. Molosse; Guilherme L. Deolindo; Patricia Glombosky; Wanderson A.B. Pereira; Raissa A. Carvalho; Claiton A. Zotti; Gabriela Solivo; Marcelo Vedovato; Mateus Fracasso; Anielen D. Silva; Vera M. Morsch; Aleksandro Schafer da Silva
Source:
Livestock science 2022 v.263 pp. 105029
ISSN:
1871-1413
Subject:
carvacrol,   etc   ; bambermycin; body weight; curcumin; diet; growth performance; leukocytes; microencapsulation; monensin; thymol; weight gain;     Show all 11 Subjects
Abstract:
... The objective was to determine whether the inclusion of curcumin and microencapsulated phytogenic (alone or combined) could replace the combination of ionophore and non-ionophore antibiotics in the diet of calves in the initial breeding phase and maintain zootechnical performance. The microencapsulated phytogenic blend used in this study contained carvacrol, cinnamaldehyde, and thymol. Twenty-four ...
DOI:
10.1016/j.livsci.2022.105029

13. Determination of chemical component of essential oil of Origanum dubium plants grown at different altitudes and antifungal activity against Sclerotinia sclerotiorum

Author:
Musa Türkmen; Merve Kara; Hasan Maral; Soner Soylu
Source:
Journal of food processing and preservation 2022 v.46 no.6 pp. e15787
ISSN:
0145-8892
Subject:
carvacrol,   etc   ; Origanum; Sclerotinia sclerotiorum; altitude; antifungal properties; chemical composition; essential oils; fungi; linalool; p-cymene;     Show all 10 Subjects
Abstract:
... The aim of this study was to determine effect of altitude on the yields, composition, and antifungal activities of the essential oil isolated from Origanum dubium plant populations collected at four different altitudes. The essential oil yield, the content of four compounds and antifungal activities against Sclerotinia sclerotiorum were found to vary in relation to the different altitudes examined ...
DOI:
10.1111/jfpp.15787

14. A review of effective essential oils and their biologically active compounds to protect the safety of food stored against insect pests

Author:
Zahra Moshrefi Zenoozi; Batool Soltaninezhad; Mohammad Hashemi; Seyyed Mohammad Ali Noori
Source:
Journal of essential oil research 2022 v.34 no.2 pp. 111-122
ISSN:
2163-8152
Subject:
carvacrol,   etc   ; cineole; essential oils; eugenol; food safety; humans; limonene; myrcene; population growth; research; secretion; thymol;     Show all 12 Subjects
Abstract:
... With population growth and the increasing human demand for crops, chemical insecticides have been used to reduce pests. Due to the adverse effects of these chemicals on the environment and health, several studies have investigated alternatives such as natural insecticides derived from essential oils or plant extracts. This review article was provided by using search engines such as Google scholar, ...
DOI:
10.1080/10412905.2022.2032420

15. Evaluation of the slow-release polylactic acid/polyhydroxyalkanoates active film containing oregano essential oil on the quality and flavor of chilled pufferfish (Takifugu obscurus) fillets

Author:
Hui Zheng; Haibing Tang; Chunxiang Yang; Jingwen Chen; Li Wang; Qingfeng Dong; Wenzheng Shi; Li Li; Yuan Liu
Source:
Food chemistry 2022 v.385 pp. 132693
ISSN:
0308-8146
Subject:
carvacrol,   etc   ; Takifugu obscurus; active ingredients; adsorption; flavor; food chemistry; montmorillonite; oregano oil; polylactic acid; shelf life;     Show all 10 Subjects
Abstract:
... Active packaging is an innovative and effective way to extend the shelf life of food, but few studies have focused on the effect of its active ingredients on food flavor. This study aimed to develop slow-release polylactic acid/polyhydroxyalkanoates (PLA/PHA) active packaging containing oregano essential oil (OEO) and investigate the effect of active composite packaging on the flavor and quality o ...
DOI:
10.1016/j.foodchem.2022.132693

16. PHB/PLA plasticized by olive oil and carvacrol solvent-cast films with optimised ductility and physical ageing stability

Author:
Demetres Briassoulis; Ioanna-Georgia Athanasoulia; Philippos Tserotas
Source:
Polymer degradation and stability 2022 v.200 pp. 109958
ISSN:
0141-3910
Subject:
carvacrol,   etc   ; biodegradability; brittleness; chemical structure; commercialization; degradation; extrusion; olive oil; polyhydroxybutyrate; polylactic acid; solvents; thermal properties;     Show all 12 Subjects
Abstract:
... Polylactic acid (PLA) is a bio-based polyester, widely used in various compostable food packaging film applications. Polyhydroxybutyrate (PHB), the most commercialised polymer of the PHA polyesters family, is one of the preferred bio-based polymers for food packaging, mainly because of its biodegradability in natural and controlled environments, and its good gas barrier properties. PHB, being a ra ...
DOI:
10.1016/j.polymdegradstab.2022.109958

17. The effects of different disinfectants and application conditions on microbial contaminants at dairy processing line

Author:
Ganga Dewi Pacheappan; Nik Iskandar Putra Samsudin; Hanan Hasan
Source:
Journal of food processing and preservation 2022 v.46 no.1 pp. e16172
ISSN:
0145-8892
Subject:
carvacrol,   etc   ; Bacillus subtilis; Escherichia coli; Staphylococcus aureus; biofilm; cost effectiveness; dairy industry; disinfectants; microbial contamination; temperature;     Show all 10 Subjects
Abstract:
... Disinfectants are very crucial in reducing microbial contaminants at dairy processing lines. However, there are limitations of their efficacy due to broad spectrum of microorganisms. Therefore, the aim of the present work was to investigate varying implementation conditions of disinfectants, Oxonia Active, Whisper V, and carvacrol, that could give the highest reduction of foodborne pathogens. The ...
DOI:
10.1111/jfpp.16172

18. The Beneficial Effect of Carvacrol in HL-1 Cardiomyocytes Treated with LPS-G: Anti-Inflammatory Pathway Investigations

Author:
Guya Diletta Marconi; Ylenia Della Rocca; Luigia Fonticoli; Simone Guarnieri; Simone Carradori; Thangavelu Soundara Rajan; Jacopo Pizzicannella; Francesca Diomede
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
carvacrol,   etc   ; Porphyromonas gingivalis; Western blotting; anti-inflammatory activity; antioxidants; cardiomyocytes; fluorescent antibody technique; lipopolysaccharides; monoterpenoids; protective effect;     Show all 10 Subjects
Abstract:
... Carvacrol (CAR), a natural phenolic monoterpene, possesses different biological activities, such as anti-inflammatory and antioxidant activities. The current study aimed to evaluate the response of HL-1 cardiomyocytes to an inflammatory stimulus triggered by lipopolysaccharide from Porphyromonas gingivalis (LPS-G), alone or in co-treatment with CAR, to investigate the potential protective role of ...
DOI:
10.3390/antiox11020386

19. Fabrication of electrospun nanofibers with moisture‐triggered carvacrol release in fresh produce packaging

Author:
Chun Hong Wong; Ming Yan Tan; Xu Li; Dan Li
Source:
Journal of food science 2022 v.87 no.7 pp. 3129-3137
ISSN:
0022-1147
Subject:
carvacrol,   etc   ; encapsulation; food preservation; food quality; fresh produce; headspace analysis; humidity; nanofibers; polyethylene glycol; polylactic acid; shelf life;     Show all 11 Subjects
Abstract:
... In this study, by incorporating polyethylene glycol (PEG) into the polylactic acid (PLA) nanofibers, a moisture‐controlled system was developed in the release of carvacrol to the food package headspaces. With the use of electrospinning technology, an optimized solution (80:20 [PLA:PEG] polymer mixture incorporated with a carvacrol content of 20% [w/w polymer]) generated nanofibers with excellent e ...
DOI:
10.1111/1750-3841.16206

20. In vitro activity of carvacrol in combination with meropenem against carbapenem-resistant Klebsiella pneumoniae

Author:
Elif Odabaş Köse
Source:
Folia microbiologica 2022 v.67 no.1 pp. 143-156
ISSN:
0015-5632
Subject:
carvacrol,   etc   ; Klebsiella pneumoniae; antimicrobial properties; beta-lactamase; cytotoxicity; meropenem; minimum inhibitory concentration; polymerase chain reaction; toxicity testing; viability;     Show all 10 Subjects
Abstract:
... Carbapenem resistance observed in Klebsiella pneumoniae strains limits treatment options. Therefore, use of antibiotics combined with bioactive compounds may be an important strategy to control K. pneumoniae. The purpose of this study was to evaluate the activity of combination of carvacrol and meropenem on carbapenem-resistant K. pneumoniae (CRKP) strains. The presence of blaOXA₋₄₈ carbapenemase ...
DOI:
10.1007/s12223-021-00908-7