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1. Using clinical history taking chatbot mobile app for clinical bedside teachings – A prospective case control study

Author:
Michael Co; Tsz Hon John Yuen; Ho Hung Cheung
Source:
Heliyon 2022 v.8 no.6 pp. e09751
ISSN:
2405-8440
Subject:
case-control studies,   etc   ; females; males; patients;     Show all 4 Subjects
Abstract:
... A novel chatbot mobile app for training of undergraduate medical students’ clinical history taking skills was developed in 2021. Students were able to take clinical history from the virtual patient for bedside teaching. A case-control study was conducted to evaluate the effectiveness of learning with chatbot mobile app, versus conventional bedside teachings with real patients. 132 final year medic ...
DOI:
10.1016/j.heliyon.2022.e09751

2. Effectiveness of typhoid conjugate vaccine in Zimbabwe used in response to an outbreak among children and young adults: A matched case control study

Author:
Maria S. Lightowler; Portia Manangazira; Fabienne Nackers; Michel Van Herp; Isaac Phiri; Kuziwa Kuwenyi; Isabella Panunzi; Daniela Garone; Farayi Marume; Andrew Tarupiwa; Eva Ferreras; Clemence Duri; Francisco J. Luquero
Source:
Vaccine 2022 v.40 no.31 pp. 4199-4210
ISSN:
0264-410X
Subject:
case-control studies,   etc   ; typhoid fever; vaccination; vaccines; Zimbabwe;     Show all 5 Subjects
Abstract:
... Zimbabwe suffers from regular outbreaks of typhoid fever (TF), worse since 2017. Most cases were in Harare and a vaccination campaign with Typhoid Conjugate Vaccine (TCV) was conducted in March 2019. The vaccine effectiveness (VE) was assessed against culture-confirmed S. Typhi in children six months to 15 years and in individuals six months to 45 years in Harare. A matched case-control study was ...
DOI:
10.1016/j.vaccine.2022.04.093

3. GAS5/METTL14/ESR1 genetic variants are related to the susceptibility of coronary heart disease

Author:
Yuxiao Sun; Zhaoyun Cheng; Mingxia Cui; Yan Chen; Ruigang Xie; Guoqing Lu; Chuanyu Gao
Source:
Functional & integrative genomics 2022 v.22 no.3 pp. 341-357
ISSN:
1438-793X
Subject:
case-control studies,   etc   ; coronary disease; diabetes; genomics; risk;     Show all 5 Subjects
Abstract:
... The prevention and treatment of coronary heart disease (CHD) is a difficult problem to be solved urgently. Genetic factors play a crucial role in CHD development. This study aimed to investigate the association of GAS5/METTL14/ESR1 polymorphisms with CHD susceptibility. We carried out a case–control study that included 506 patients and 506 healthy subjects to detect the correlation between GAS5/ME ...
DOI:
10.1007/s10142-022-00831-1

4. Delayed cerebral ischemia associated with surgery for pituitary macroadenomas that express elevated levels of PACAP

Author:
Dominic A. Siler; Kate U. Rosen; Stephen G. Bowden; Andrew Y. Powers; Jesse J. Liu; Aclan Dogan; Holly E. Hinson; Maria Fleseriu; Randy L. Woltjer; Justin S. Cetas
Source:
Brain hemorrhages 2022 pp. -
ISSN:
2589-238X
Subject:
case-control studies,   etc   ; brain; immunohistochemistry; ischemia; neoplasms; neuropeptides; polypeptides;     Show all 7 Subjects
Abstract:
... Delayed cerebral ischemia (DCI) and cerebral vasospasm (VS) are rare but serious post-operative complications after surgery for pituitary macroadenomas; the mechanism of which are poorly understood. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a vasoactive neuropeptide expressed in pituitary adenomas and may play a role in DCI/VS. The aim of this case-control study was to investig ...
DOI:
10.1016/j.hest.2022.05.003

5. CT imaging of dogs with perineal hernia reveals large prostates with morphological and spatial abnormalities

Author:
Tuuli M. Åhlberg; Hanna M Salonen; Outi M Laitinen‐Vapaavuori; Sari H Mölsä
Source:
Veterinary radiology & ultrasound 2022 v.63 no.5 pp. 530-538
ISSN:
1058-8183
Subject:
case-control studies,   etc   ; dogs; etiology; hernia; males; radiology; ultrasonics; vertebrae;     Show all 8 Subjects
Abstract:
... The etiology of canine perineal hernia (PH) remains unclear, although as a disease of older male dogs, it is likely to be hormonal. The role of the prostate in the formation of PH has been questioned; however, prospective and systematic evaluation of prostates in these dogs is absent in the literature. In this prospective case–control study, CT imaging was used to assess prostatic changes in dogs ...
DOI:
10.1111/vru.13087

6. Healthy diet associated with better asthma outcomes in elderly women of the French Asthma-E3N study

Author:
Wassila Ait-hadad; Annabelle Bédard; Sébastien Chanoine; Orianne Dumas; Nasser Laouali; Nicole Le Moual; Bénédicte Leynaert; Conor Macdonald; Valérie Siroux; Marie-Christine Boutron-Ruault; Raphaëlle Varraso
Source:
European journal of nutrition 2022 v.61 no.5 pp. 2555-2569
ISSN:
1436-6207
Subject:
case-control studies,   etc   ; asthma; elderly; food intake; healthy diet; risk;     Show all 6 Subjects
Abstract:
... PURPOSE: The impact of a healthy diet on asthma prevention and management, particularly among elderly women, remains poorly understood. We investigated whether a healthy diet would be associated with fewer asthma symptoms, and, among women with asthma, with reduced uncontrolled asthma and metabolic-related multimorbidity. METHODS: We included 12,991 elderly women (mean age = 63 years) from the Ast ...
DOI:
10.1007/s00394-022-02815-0

7. A combined healthy lifestyle score in relation to glioma: a case-control study

Author:
Soraiya Ebrahimpour-Koujan; Mehdi Shayanfar; Minoo Mohammad-Shirazi; Giuve Sharifi; Ahmad Esmaillzadeh
Source:
Nutrition journal 2022 v.21 no.1 pp. 6
ISSN:
1475-2891
Subject:
case-control studies,   etc   ; glioma; healthy diet; lifestyle; physical activity; questionnaires; risk;     Show all 7 Subjects
Abstract:
... BACKGROUND: The evidence on the association between adherence to a healthy lifestyle and risk of glioma are scarce. This is particularly relevant to Middle Eastern countries where lifestyle factors including dietary intakes, physical activity and environmental contributors are different from other parts of the world. The aim of this case-control study was, therefore, investigating the association ...
DOI:
10.1186/s12937-022-00758-0

8. miR-146a, miR-196a2, miR-499, and miR-149 linked with susceptibility to acute lymphoblastic leukemia: A case-control study in Tunisia

Author:
Amani Dhiflaoui; Sana Mahjoub; Vera Chayeb; Bechir Achour; Saoussen Chouchen; Hassen Ben Abdennebi; Touhami Mahjoub; Wassim Y. Almawi
Source:
Gene 2022 v.834 pp. 146648
ISSN:
0378-1119
Subject:
case-control studies,   etc   ; alleles; biomarkers; genotype; lymphocytic leukemia; microRNA; risk; Tunisia;     Show all 8 Subjects
Abstract:
... MicroRNAs (miRNAs) are promising biomarkers of hematological malignancies, including acute lymphoblastic leukaemia (ALL). Recent studies revealed that miRNA single nucleotide polymorphisms (miR-SNP) modulate cancer risk by regulating various signaling pathways. However, their association with altered risk of ALL yielded inconsistent results. This study aims to investigate the association of four m ...
DOI:
10.1016/j.gene.2022.146648

9. Dietary Inflammatory Index and Breast Cancer: report from a Large-Scale Case-Control Study

Author:
Bahareh Sasanfar; Fatemeh Toorang; Maedeh Mozafari Nia; Amin Salehi-Abargouei; Kazem Zendehdel
Source:
Nutrition and cancer 2022 v.74 no.5 pp. 1692-1700
ISSN:
1532-7914
Subject:
case-control studies,   etc   ; breast neoplasms; food intake; postmenopause; premenopause; regression analysis;     Show all 6 Subjects
Abstract:
... The relationship between diet, including its inflammatory potential, and breast cancer has led to inconsistent results. We investigated the association between a dietary inflammatory index (DII) and the odds of breast cancer in a large case-control study among women. This case-control study was carried out on 412 women with pathologically confirmed breast cancer and 456 apparently healthy controls ...
DOI:
10.1080/01635581.2021.1957489

10. Incidence and demographic risk factors for leptospirosis in dogs in the UK

Author:
Collette Taylor; Dan G. O'Neill; Brian Catchpole; Dave C. Brodbelt
Source:
Veterinary record 2022 v.190 no.6 pp. e512
ISSN:
0042-4900
Subject:
case-control studies,   etc   ; adults; crossbreds; kennels; leptospirosis; odds ratio; regression analysis;     Show all 7 Subjects
Abstract:
... OBJECTIVES: To estimate the annual incidence risk of leptospirosis diagnosis in practice‐attending dogs in the UK during 2016 and identify risk factors for diagnosis. METHODS: Incidence of leptospirosis diagnosis in dogs during 2016 was estimated from dogs in primary‐care practices from the VetCompass Programme (n = 905,543). A case‐control study of laboratory cases (n = 362) versus VetCompass con ...
DOI:
10.1002/vetr.512

11. Plasma l-carnitine and risks of cardiovascular events and recurrent stroke after ischemic stroke: A nested case-control study

Author:
Jigang Du; Mengyuan Miao; Zian Lu; Haichang Chen; Anran Bao; Bizhong Che; Jintao Zhang; Zhong Ju; Tan Xu; Jiang He; Yonghong Zhang; Chongke Zhong
Source:
Nutrition, metabolism, and cardiovascular diseases 2022 pp. -
ISSN:
0939-4753
Subject:
case-control studies,   etc   ; atherosclerosis; carnitine; metabolism; nutrition; regression analysis; risk; stroke;     Show all 8 Subjects
Abstract:
... l-Carnitine was suggested to prevent the progression of atherosclerosis, myocardial and neurologic injury, and exhibited cardioprotective effects. However, epidemiological data on circulating l-carnitine and risks of cardiovascular events in the setting of stroke is rare. We aimed to explore the relationships between plasma l-carnitine and cardiovascular events and stroke recurrence after ischemic ...
DOI:
10.1016/j.numecd.2022.08.016

12. Inflammatory Potential of Diet and Odds of Lung Cancer: A Case-Control Study

Author:
Alireza Sadeghi; Karim Parastouei; Sharareh Seifi; Adnan Khosravi; Babak Salimi; Hoda Zahedi; Omid Sadeghi; Hamid Rasekhi; Maryam Amini
Source:
Nutrition and cancer 2022 v.74 no.8 pp. 2859-2867
ISSN:
1532-7914
Subject:
case-control studies,   etc   ; food frequency questionnaires; lung neoplasms; males; mortality; Middle East;     Show all 6 Subjects
Abstract:
... Lung cancer is one of the common types of malignant disorders and the most prevalent cause of cancer mortality worldwide. Few studies have examined the association of dietary inflammatory index (DII) with lung cancer and findings from these studies are conflicting. Moreover, no study has examined this association in the Middle East. Therefore, the current case-control study was conducted to examin ...
DOI:
10.1080/01635581.2022.2036770

13. Mendelian Randomization Analysis of the Association of SOCS3 Methylation with Abdominal Obesity

Author:
Yuqian Li; Xiaotian Liu; Runqi Tu; Jian Hou; Guihua Zhuang
Source:
Nutrients 2022 v.14 no.18 pp. -
ISSN:
2072-6643
Subject:
case-control studies,   etc   ; genotyping; methylation; obesity; regression analysis; single nucleotide polymorphism; variance;     Show all 7 Subjects
Abstract:
... This study was conducted to evaluate the potential causality association of SOCS3 methylation with abdominal obesity using Mendelian randomization. A case–control study, including 1064 participants, was carried out on Chinese subjects aged 18 to 79. MethylTargetTM was used to detect the methylation level for each CpG site of SOCS3, and SNPscan® was applied to measure the single-nucleotide polymorp ...
DOI:
10.3390/nu14183824

14. Exposure to metal mixtures and hypertensive disorders of pregnancy: A nested case-control study in China

Author:
Jiaolong Ma; Hongling Zhang; Tongzhang Zheng; Wenxin Zhang; Chenhui Yang; Ling Yu; Xiaojie Sun; Wei Xia; Shunqing Xu; Yuanyuan Li
Source:
Environmental pollution 2022 v.306 pp. 119439
ISSN:
0269-7491
Subject:
case-control studies,   etc   ; Bayesian theory; pollution; pregnancy; regression analysis; risk; thallium; vanadium;     Show all 8 Subjects
Abstract:
... Exposure to metals has been linked with the risk of hypertensive disorders of pregnancy (HDP), but little is known about the potential effects of exposure to metal mixtures. Thus, our study aimed to investigated the impact of a complex mixture of metals on HDP, especially the interactions among metal mixtures. We did a population-based nested case-control study from October 2013 to October 2016 in ...
DOI:
10.1016/j.envpol.2022.119439

15. Evaluation of association with subtypes and alleles of Blastocystis with chronic spontaneous urticaria

Author:
Mehmet Aykur; Asuman Camyar; Bengü Gerceker Türk; Aytül Zerrin Sin; Hande Dagci
Source:
Acta tropica 2022 v.231 pp. 106455
ISSN:
0001-706X
Subject:
case-control studies,   etc   ; Blastocystis; DNA barcoding; alleles; gastrointestinal system; parasites; pruritus; urticaria;     Show all 8 Subjects
Abstract:
... Blastocystis is a single-celled parasite commonly found in humans and its pathogenic role is still controversial. In recent years, some studies have suggested that Blastocystis may be a possible agent of gastrointestinal and dermatological symptoms such as acute or chronic urticaria, angioedema, rash, itch, palmoplantar, and diffuse pruritus. We aimed to investigate whether there is a relationship ...
DOI:
10.1016/j.actatropica.2022.106455

16. Evaluation of efficacy and safety of adjuvant Ayurvedic therapy in patients with severe post-covid mucor-mycosis at a Government tertiary care hospital – A Case-Control study

Author:
Uma Shankar Prasad Adluri; Srikanthbabu Perugu
Source:
Journal of Ayurveda and integrative medicine 2022 v.13 no.3 pp. 100585
ISSN:
0975-9476
Subject:
case-control studies,   etc   ; Ayurvedic medicine; Mucor; adjuvants; disease progression; hospitals; mortality; zygomycosis;     Show all 8 Subjects
Abstract:
... In the wake of the unprecedented Mucormycosis epidemic following the delta variant run second wave of SARS COV-2, the Government of Telangana decided to utilize Ayurveda for its adjuvant immune-boosting role. Based on clinical assessment of patients, Mucor mycosis was identified as Vataja vidradhi and treatment was planned. To assess the safety and efficacy of Ayurvedic regime as an adjuvant thera ...
DOI:
10.1016/j.jaim.2022.100585

17. Living near coasts is associated with higher suicide rates among females but not males: A register-based linkage study in the Netherlands

Author:
Marco Helbich; Matthew H.E.M. Browning; Mathew White; Paulien Hagedoorn
Source:
Science of the total environment 2022 v.845 pp. 157329
ISSN:
0048-9697
Subject:
case-control studies,   etc   ; behavior disorders; coasts; distress; environment; income; risk; suicide; Netherlands;     Show all 9 Subjects
Abstract:
... Exposure to blue spaces may promote psychological wellbeing and reduce mental distress. Whether these effects extend to suicide is unknown. We used register data from 14 million Dutch adults aged 18–64-years between 2007 and 2016 in a nested case-control study to estimate associations between blue space exposures and suicide risk. Each suicide case was matched to ten randomly selected controls. Tw ...
DOI:
10.1016/j.scitotenv.2022.157329

18. METTL14 gene polymorphisms influence hepatoblastoma predisposition in Chinese children: Evidences from a seven-center case-control study

Author:
Huitong Chen; Zhen Chen; Mi Wang; Jiao Zhang; Yong Li; Li Li; Suhong Li; Jiwen Cheng; Xianqiang Wang; Huimin Xia; Zhonghua Yang; Jing He
Source:
Gene 2022 v.809 pp. 146050
ISSN:
0378-1119
Subject:
case-control studies,   etc   ; carcinogenesis; etiology; genes; genotype; genotyping; methyltransferases; quantitative traits; risk;     Show all 9 Subjects
Abstract:
... Hepatoblastoma as the most prevalent hepatic malignancy in children, its etiology remains unclear. N⁶-Methyladenosine (m⁶A) modification which can modify various physiological processes, plays a critical role in tumorigenesis. Methyltransferase-like 14 (METTL14), an important component of the m⁶A methyltransferase complex, remains elusive during hepatoblastoma occurrence and development. We explor ...
DOI:
10.1016/j.gene.2021.146050

19. Spatial Variation in Risk for Highly Pathogenic Avian Influenza Subtype H5N6 Viral Infections in South Korea: Poultry Population-Based Case–Control Study

Author:
Saleem Ahmad; Kye-Young Koh; Dae-Sung Yoo; Jae-Il Lee
Source:
Veterinary sciences 2022 v.9 no.3 pp. -
ISSN:
2306-7381
Subject:
case-control studies,   etc   ; avian influenza; biosecurity; computer software; poultry; risk; South Korea;     Show all 7 Subjects
Abstract:
... Given the substantial economic damage caused by the continual circulation of highly pathogenic avian influenza (HPAI) outbreaks since 2003, identifying high-risk locations associated with HPAI infections is essential. In this study, using affected and unaffected poultry farms’ locations during an HPAI H5N6 epidemic in South Korea, we identified places where clusters of HPAI cases were found. Hotsp ...
DOI:
10.3390/vetsci9030135

20. Associations of Evolutionary-Concordance Diet and Lifestyle Pattern Scores with Incident, Sporadic Colorectal Adenoma in a Pooled Case-Control Study

Author:
McKenna J. Penley; Doratha A. Byrd; Roberd M. Bostick
Source:
Nutrition and cancer 2022 v.74 no.6 pp. 2075-2087
ISSN:
1532-7914
Subject:
case-control studies,   etc   ; adenoma; colorectal neoplasms; confidence interval; diet; lifestyle; regression analysis; risk;     Show all 8 Subjects
Abstract:
... Differences in diet and lifestyle relative to those of our Paleolithic-era ancestors may explain current high incidences of chronic diseases, including colorectal cancer (CRC), in Westernized countries. Previously reported evolutionary-concordance diet and lifestyle pattern scores, reflecting closeness of diet and lifestyle patterns to those of Paleolithic-era humans, were associated with lower CR ...
DOI:
10.1080/01635581.2021.2002919