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1. Development of a three dimensional (3D) knitted scaffold for myocardial tissue engineering. Part II: biological performance of the knitted scaffolds

Author:
Derya Haroglu; Ahmet Eken; Zeynep Burçin Gönen; Dilek Bahar
Source:
The journal of the Textile Institute 2025 v.113 no.5 pp. 895-905
ISSN:
1754-2340
Subject:
cell adhesion,   etc   ; adhesion; anisotropy; cell lines; fabrics; fibronectins; humans; interleukin-11; medicine; mice; myoblasts; myocardial infarction; myocardium; polyethylene terephthalates; porosity; therapeutics;     Show all 16 Subjects
Abstract:
... Cardiac patch has been proposed as an alternative therapeutic tissue engineering strategy to treat damaged heart for patients who survive the acute myocardial infarction (MI). To that end, studies have focused on designing an ideal cardiac patch assisting myocardium to repair itself. The engineering of three dimensional (3 D) anisotropic knitted scaffolds could be an efficient and effective strate ...
DOI:
10.1080/00405000.2021.1907990

2. miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β

Author:
Hongxin Xu; Ying Cui; Xianwei Liu; Xiao Zheng; Jiaqing Liu; Xinxin Hu; Fuhua Gao; Xiaoyan Hu; Mei Li; Xiaoqing Wei; Ying Gao; Ying Zhao
Source:
Molecular biology reports 2022 v.49 no.3 pp. 1871-1882
ISSN:
0301-4851
Subject:
cell adhesion; vascular cell adhesion molecules,   etc   ; adhesion; atherosclerosis; blood serum; hyperlipidemia; inflammation; intercellular adhesion molecule-1; interleukin-8; luciferase; molecular biology;     Show all 11 Subjects
Abstract:
... BACKGROUND: MicroRNA-1290 (miR-1290) has been reported to be involved in many diseases and play a key role during the development process. However, the role of miR-1290 in atherosclerosis (AS) is still unclear. METHODS AND RESULTS: The current study showed that the expressions of miR-1290 were high in serum of patients with hyperlipidemia. The functional role of miR-1290 were then investigated in ...
DOI:
10.1007/s11033-021-06998-3

3. Construction of a stereocomplex between poly(d-lactide) grafted hydroxyapatite and poly(l-lactide): toward a bioactive composite scaffold with enhanced interfacial bonding

Author:
Cijun Shuai; Li Yu; Pei Feng; Shuping Peng; Hao Pan; Xinna Bai
Source:
Journal of materials chemistry B 2022 v.10 no.2 pp. 214-223
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; bioactive properties; hydrogen; hydroxyapatite; polymerization; tensile strength;     Show all 6 Subjects
Abstract:
... The poly(l-lactide) (PLLA)/hydroxyapatite (HAP) composite scaffold is expected to combine the favorable compatibility and processability of PLLA with the excellent bioactivity and osteoconductivity of HAP. Unfortunately, the poor interfacial bonding between PLLA and HAP leads to a deterioration in mechanical properties. In this study, poly(d-lactide) (PDLA) was grafted onto the surface of HAP nano ...
DOI:
10.1039/d1tb02111g

4. Epithelial cell adhesion molecule (EpCAM) binding short peptides derived from antibody MOC-31; De-novo design, synthesis and their in-vitro evaluation

Author:
Suchita D. Shinde; Kamya B. Rao; Santosh K. Behera; Neha Arya; Bichismita Sahu
Source:
Biochemical and biophysical research communications 2022 v.600 pp. 1-5
ISSN:
0006-291X
Subject:
epithelial cell adhesion molecule,   etc   ; antibodies; dissociation; neoplasms; peptides; research;     Show all 6 Subjects
Abstract:
... Epithelial cell adhesion molecule (EpCAM) is one of the critical bio-maker for circulating tumor cells (CTC) detection. For capturing CTC, antibody-antigen-based techniques have mainly been explored. However, the expensiveness and tedious manufacturing process have posed certain limitations for antibody-based techniques for its wide applications in cell capturing. On the other hand, peptides are i ...
DOI:
10.1016/j.bbrc.2022.01.120

5. Determination of red blood cell adhesion to vascular endothelial cells: A critical role for blood plasma

Author:
Gregory Barshtein; Orly Zelig; Alexander Gural; Dan Arbell; Saul Yedgar
Source:
Colloids and surfaces 2022 v.210 pp. 112226
ISSN:
0927-7765
Subject:
cell adhesion,   etc   ; adhesion; blood plasma; erythrocytes; humans; pathophysiology; shear stress;     Show all 7 Subjects
Abstract:
... Red blood cell (RBC) adhesion to vascular endothelial cells (EC) is considered a potent effector of circulatory disorders, and its enhancement is implicated in the pathophysiology of numerous conditions, mainly hemoglobinopathies. The actual RBC/EC interaction is determined by both cellular and plasmatic factors, and the differentiation between them is essential for understanding its physiological ...
DOI:
10.1016/j.colsurfb.2021.112226

6. JAM-A interacts with α3β1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells

Author:
Sonja Thölmann; Jochen Seebach; Tetsuhisa Otani; Luise Florin; Hans Schnittler; Volker Gerke; Mikio Furuse; Klaus Ebnet
Source:
Cellular and molecular life sciences 2022 v.79 no.2 pp. 88
ISSN:
1420-682X
Subject:
cell adhesion,   etc   ; adhesion; cell movement; epithelium; fibronectins; integrins; laminin; pseudopodia;     Show all 8 Subjects
Abstract:
... Junctional adhesion molecule (JAM)-A is a cell adhesion receptor localized at epithelial cell–cell contacts with enrichment at the tight junctions. Its role during cell–cell contact formation and epithelial barrier formation has intensively been studied. In contrast, its role during collective cell migration is largely unexplored. Here, we show that JAM-A regulates collective cell migration of pol ...
DOI:
10.1007/s00018-022-04140-5

7. Establishment of a luciferase-based method for measuring cancer cell adhesion and proliferation

Author:
Stine Bull Jessen; Derya Coskun Özkul; Yasemin Özen; Ismail Gögenur; Jesper T. Troelsen
Source:
Analytical biochemistry 2022 v.650 pp. 114723
ISSN:
0003-2697
Subject:
cell adhesion,   etc   ; adhesion; blood serum; cell proliferation; genome; luciferase; neoplasm cells;     Show all 7 Subjects
Abstract:
... Methods measuring cell proliferation and adhesion are widely used but each hold limitations. We, therefore, introduce novel methods for measuring cell proliferation and adhesion based on CRISPR-modified cancer cell lines secreting luciferase to the growth media. Using CRISPR genome editing, we generated stable luciferase-secreting LS174T, HCT 116, Caco-2, and PANC-1 cell lines. The modified cells ...
DOI:
10.1016/j.ab.2022.114723

8. Expression of αV integrin and its potential partners in bull reproductive tissues, germ cells and spermatozoa

Author:
Jana Antalíková; Petra Sečová; Katarína Michalková; Ľubica Horovská; Veronika Páleníková; Jana Jankovičová
Source:
International journal of biological macromolecules 2022 v.209 pp. 542-551
ISSN:
0141-8130
Subject:
cell adhesion,   etc   ; acrosome; ejaculation; epididymis; exocytosis; integrins; plasma membrane; spermatids; testes;     Show all 9 Subjects
Abstract:
... Integrins are transmembrane receptors expressed in all nucleated mammalian cells, critically involved in cell-matrix adhesion and cell-cell interactions that modulate many signalling cascades. It is assumed that integrins also provide essential functions of the reproductive system. In this study, we describe the detailed localization and distribution of αV integrin in the plasma membrane of bull s ...
DOI:
10.1016/j.ijbiomac.2022.04.001

9. The restricted adhesion of bone marrow mesenchymal stem cells by stepped structures on surfaces of hydroxyapatite

Author:
Jin Chen; Zhuo Huang; Fang Wang; Min Gong; Xueli Zhang; Yajing Wang; Zuquan Hu; Zhu Zeng; Yun Wang
Source:
RSC advances 2022 v.12 no.19 pp. 12002-12010
ISSN:
2046-2069
Subject:
cell adhesion,   etc   ; adhesion; bone marrow; crystal structure; crystallization; hydroxyapatite; models; roughness;     Show all 8 Subjects
Abstract:
... Currently, many researches have developed several strategies to design the surface structures of hydroxyapatite (HA), and have proved that the surface structures are pivotal in guiding the adhesion of bone marrow mesenchymal stem cells (BMSCs) as well as subsequent cellular behaviours. Most of these strategies, such as altering roughness and constructing surface patterning of HA, involve the const ...
DOI:
10.1039/d2ra00756h

10. Deep whole-genome resequencing sheds light on the distribution and effect of amphioxus SNPs

Author:
Yunchi Zhu; Na Lu; J.-Y. Chen; Chunpeng He; Zhen Huang; Zuhong Lu
Source:
BMC genomic data 2022 v.23 no.1 pp. 26
ISSN:
2730-6844
Subject:
cell adhesion,   etc   ; data collection; genomics; haploidy; phenotype; protein structure; signal transduction; vertebrates;     Show all 8 Subjects
Abstract:
... BACKGROUND: Amphioxus is a model organism for vertebrate evolutionary research. The significant contrast between morphological phenotypic similarity and high-level genetic polymorphism among amphioxus populations has aroused scientists' attention. Here we resequenced 21 amphioxus genomes to over 100X depth and mapped them to a haploid reference. RESULTS: More than 11.5 million common SNPs were det ...
DOI:
10.1186/s12863-022-01038-w

11. Preparation of Assemblable Chondral and Subchondral Bone Microtissues for Osteochondral Tissue Engineering

Author:
Pengfei Xia; Shifeng Yan; Guifei Li; Jingbo Yin
Source:
ACS applied materials & interfaces 2022 v.14 no.10 pp. 12089-12105
ISSN:
1944-8252
Subject:
cell adhesion,   etc   ; bone formation; bones; cartilage; chemical reactions; hydrophilicity; microgels; porosity; tissue repair;     Show all 9 Subjects
Abstract:
... Microtissues exhibit great advantages in injecting with minimum invasiveness, mimicking natural tissues, and promoting tissue regeneration. However, very few studies have focused on the construction of osteochondral microtissues that could simultaneously support hyaline-like cartilage and bone tissue regeneration. In this study, chondral microtissues that could favor the formation of hyaline-like ...
DOI:
10.1021/acsami.2c00997

12. DNA modified MSN-films as versatile biointerfaces to study stem cell adhesion processes

Author:
Xingzhen Zhang; Sabine van Rijt
Source:
Colloids and surfaces 2022 v.215 pp. 112495
ISSN:
0927-7765
Subject:
cell adhesion,   etc   ; adhesion; complementary DNA; extracellular matrix; ligands; porous media; silica; stem cells; tripeptides;     Show all 9 Subjects
Abstract:
... A significant bottleneck in the clinical translation of stem cells remains eliciting the desired stem cell behavior once transplanted in the body. In their natural environment, stem cell fate is regulated by their interaction with extracellular matrix (ECM), mainly through integrin-mediated cell adhesion. 2D biointerfaces that selectively present ECM-derived ligands can be used as valuable tools t ...
DOI:
10.1016/j.colsurfb.2022.112495

13. The substrate stiffness at physiological range significantly modulates vascular cell behavior

Author:
Sheng-wen Zhou; Jing Wang; Sheng-yu Chen; Ke-feng Ren; You-xiang Wang; Jian Ji
Source:
Colloids and surfaces 2022 v.214 pp. 112483
ISSN:
0927-7765
Subject:
cell adhesion,   etc   ; blood; cellular microenvironment; gene expression regulation; hydrogels; nitric oxide; phenotype; smooth muscle;     Show all 8 Subjects
Abstract:
... Changes in the stiffness of the cellular microenvironment are involved in many pathological processes of blood vessels. Substrate stiffness has been shown to have extensive effects on vascular endothelial cells (VECs) and vascular smooth muscle cells (VSMCs). However, the material stiffness of most previously reported in-vitro models is ranging from ~100 kPa to the magnitude of MPa, which does not ...
DOI:
10.1016/j.colsurfb.2022.112483

14. Fabrication of super-hydrophilic and highly open-porous poly (lactic acid) scaffolds using supercritical carbon dioxide foaming

Author:
Qian Ren; Xiuyu Zhu; Wanwan Li; Minghui Wu; Shijie Cui; Yihan Ling; Xuehua Ma; Guilong Wang; Long Wang; Wenge Zheng
Source:
International journal of biological macromolecules 2022 v.205 pp. 740-748
ISSN:
0141-8130
Subject:
cell adhesion,   etc   ; biocompatibility; carbon dioxide; cell structures; contact angle; cost effectiveness; fibroblasts; fluorescence; hydrophilicity; mice;     Show all 10 Subjects
Abstract:
... Porous poly (lactic acid) (PLA)-based scaffolds have been widely used as a promising product in tissue engineering. However, it is still a challenge to prepare the PLA-based scaffolds with high expansion ratio, good hydrophilicity, and excellent cytocompatibility by a green and cost-effective fabrication approach. Herein, we prepared porous PLA-based scaffolds using carbon dioxide (CO₂) as the phy ...
DOI:
10.1016/j.ijbiomac.2022.03.107

15. Immunological functional differentiation of two transmembrane variants of Dscam in Chinese mitten crab

Author:
Jiying Li; Ke Zhao; Hao Li; Kaimin Zhou; Qun Wang; Weiwei Li
Source:
Developmental and comparative immunology 2022 v.128 pp. 104313
ISSN:
0145-305X
Subject:
cell adhesion molecules,   etc   ; Eriocheir sinensis; antimicrobial peptides; arthropods; bioinformatics; exons; gene expression; hemocytes; intestines; phagocytosis;     Show all 10 Subjects
Abstract:
... Down syndrome cell adhesion molecule (Dscam), also called hypervariable Dscam (Dscam-hv), is an important player in arthropod alternative splicing that connects neurons and immune regulation, acting as a pathogen-specific recognition molecule. Dscam-hv has two forms: transmembrane (TM) Dscam (mDscam) and soluble Dscam (sDscam). Herein, we investigated two transmembrane variants of mDscam resulting ...
DOI:
10.1016/j.dci.2021.104313

16. Prochloraz alone or in combination with nano-CuO promotes the conjugative transfer of antibiotic resistance genes between Escherichia coli in pure water

Author:
Aiyun Guo; Qixing Zhou; Yanyu Bao; Fanghan Qian; Xu Zhou
Source:
Journal of hazardous materials 2022 v.424 pp. 127761
ISSN:
0304-3894
Subject:
cell adhesion,   etc   ; Escherichia coli; antibiotic resistance; membrane permeability; oxidative stress; plasmids; polymers; polysaccharides; prochloraz; risk;     Show all 10 Subjects
Abstract:
... Conjugative plasmid transfer is a major contributor to the spread of antibiotic resistance genes (ARGs). However, the role of conventional fungicides on conjugative plasmid transfer has been neglected. Based on the condition that the increasing use of the combination of nano- and conventional fungicides will lead to combined contamination, the effects of a conventional fungicide prochloraz alone o ...
DOI:
10.1016/j.jhazmat.2021.127761

17. Superior processability of Antheraea mylitta silk with cryo-milling: Performance in bone tissue regeneration

Author:
Nimisha Parekh; C.K. Bijosh; Kartiki Kane; Alaka Panicker; Anuya Nisal; Pralhad Wangikar; Sachin Agawane
Source:
International journal of biological macromolecules 2022 pp. -
ISSN:
0141-8130
Subject:
cell adhesion,   etc   ; Antheraea mylitta; Bombyx mori; biocompatibility; bone formation; bones; models; rats; silk; tissue repair;     Show all 10 Subjects
Abstract:
... Non-mulberry silk polymers have a promising future in biomedical applications. However, the dissolution of non-mulberry silk fiber is a still challenge and this poor processability has limited the use of this material. Here, we report a unique protocol to process the Antheraea mylitta (AM) silk fiber. We have shown that the cryo-milling of silk fiber reduces the beta sheet content by more than 10% ...
DOI:
10.1016/j.ijbiomac.2022.05.122

18. Targeting Staphylococcus aureus and its biofilms with novel antibacterial compounds produced by Lactiplantibacillus plantarum SJ33

Author:
Amrita Ray Mohapatra; Adhikesavan Harikrishnan; Divya Lakshmanan; Kadirvelu Jeevaratnam
Source:
Archives of microbiology 2022 v.204 no.1 pp. 20
ISSN:
0302-8933
Subject:
cell adhesion,   etc   ; antimicrobial properties; biofilm; fluorescence; gentian violet; methicillin-resistant Staphylococcus aureus; microbiology; molecular weight;     Show all 8 Subjects
Abstract:
... The emergence of microbial resistance to conventional antibiotics, partially attributed to biofilm formation, has urged for new antimicrobial compounds. Here, we reported two novel low molecular weight (LMW) compounds from Lactiplantibacillus plantarum SJ33 and evaluated their biofilm inhibitory effects on Staphylococcus aureus. The compounds C1 and C2 were purified by RP-HPLC and structurally ide ...
DOI:
10.1007/s00203-021-02630-x

19. Engineering of a Microscale Niche for Pancreatic Tumor Cells Using Bioactive Film Coatings Combined with 3D-Architectured Scaffolds

Author:
Arunkumar Rengaraj; Lauriane Bosc; Paul Machillot; Colin McGuckin; Clément Milet; Nico Forraz; Philippe Paliard; Denis Barbier; Catherine Picart
Source:
ACS applied materials & interfaces 2022 v.14 no.11 pp. 13107-13121
ISSN:
1944-8252
Subject:
cell adhesion,   etc   ; cell culture; dose response; fibronectins; humans; hyaluronic acid; liquids; lysine; metastasis; pancreatic neoplasms; polymerization;     Show all 11 Subjects
Abstract:
... Two-photon polymerization has recently emerged as a promising technique to fabricate scaffolds for three-dimensional (3D) cell culture and tissue engineering. Here, we combined 3D-printed microscale scaffolds fabricated using two-photon polymerization with a bioactive layer-by-layer film coating. This bioactive coating consists of hyaluronic acid and poly(l-lysine) of controlled stiffness, loaded ...
DOI:
10.1021/acsami.2c01747

20. Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome

Author:
Hwan Yeul Yu; Seungun Lee; Hyein Ju; Youngkyu Kim; Jung-Hyun Shin; HongDuck Yun; Chae-Min Ryu; Jinbeom Heo; Jisun Lim; Sujin Song; Sanghwa Lee; Ki-Sung Hong; Hyung-Min Chung; Jun Ki Kim; Myung-Soo Choo; Dong-Myung Shin
Source:
Biomaterials 2022 v.280 pp. 121277
ISSN:
0142-9612
Subject:
cell adhesion,   etc   ; animal models; biocompatible materials; bladder; cyclins; humans; interstitial cystitis; mesenchymal stromal cells; therapeutics; transcriptomics;     Show all 10 Subjects
Abstract:
... Mesenchymal stem cell (MSC) therapy is a promising treatment for various intractable disorders including interstitial cystitis/bladder pain syndrome (IC/BPS). However, an analysis of fundamental characteristics driving in vivo behaviors of transplanted cells has not been performed, causing debates about rational use and efficacy of MSC therapy. Here, we implemented two-photon intravital imaging an ...
DOI:
10.1016/j.biomaterials.2021.121277