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1. Precise regulation of particle size of poly(N-isopropylacrylamide) microgels: Measuring chain dimensions with a “molecular ruler”

Author:
Xue, Hui; Zhao, Ziqing; Chen, Rui; Brash, John L.; Chen, Hong
Source:
Journal of colloid and interface science 2020 v.566 pp. 394-400
ISSN:
0021-9797
Subject:
cell adhesion,   etc   ; crosslinking; drug carriers; microgels; particle size; temperature;     Show all 6 Subjects
Abstract:
... Hypothesis: Poly(N-isopropylacrylamide) microgels are used extensively in the design of drug carriers, surfaces for control of cell adhesion, and optical devices. Particle size is a key factor and has a significant influence in many areas.Experiments: In this work, precise control of the particle size of poly(N-isopropylacrylamide) microgels was achieved by controlling the separation distance of t ...
DOI:
10.1016/j.jcis.2020.01.076

2. Cell adhesion control by photoinduced LCST shift of PNIPAAm-based brush scaffolds

Author:
Imato, Keiichi; Nagata, Kazuho; Watanabe, Rina; Takeda, Naoya
Source:
Journal of materials chemistry B 2020 v.8 no.12 pp. 2393-2399
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; bioengineering; composite polymers; physicochemical properties; polyethylene glycol; temperature;     Show all 6 Subjects
Abstract:
... Poly(N-isopropylacrylamide) (PNIPAAm)-brush substrates are one of the most successful dynamic scaffolds for thermally controlling cell adhesion. Endowing substrates with photocontrollability promises further development and applications in the biomedical and bioengineering fields. In this study, we developed photoresponsive PNIPAAm copolymers by incorporation of spiropyran into the polymer chain, ...
DOI:
10.1039/c9tb02958c

3. Bioinspired surfaces with wettability: biomolecule adhesion behaviors

Author:
Fan, Haifeng; Guo, Zhiguang
Source:
Biomaterials science 2020 v.8 no.6 pp. 1502-1535
ISSN:
2047-4849
Subject:
cell adhesion,   etc   ; adhesion; hydrophilicity; hydrophobicity; nucleic acids; proteins; wettability;     Show all 7 Subjects
Abstract:
... Surface wettability plays an important role in regulating biomolecule adhesion behaviors. The biomolecule adhesion behaviors of superwettable surfaces have become an important topic as an important part of the interactions between materials and organisms. In addition to general research on the moderate wettability of surfaces, the studies of biomolecule adhesion behaviors extend to extreme wettabi ...
DOI:
10.1039/c9bm01729a

4. Integrated analysis of gene expression, alteration and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer

Author:
Weng, Chun-Yue; Hu, Xin-Yi; Wang, Ya-Jun
Source:
3 Biotech 2020 v.10 no.3 pp. 132
ISSN:
2190-572X
Subject:
cell adhesion; cell adhesion molecules,   etc   ; colorectal neoplasms; databases; gene expression; genes; head and neck neoplasms; lungs; mutation; pancreatic neoplasms; patients; prognosis; survival rate;     Show all 13 Subjects
Abstract:
... Even though cell–cell adhesion molecule carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is extensively studied since the discovery, the role of CEACAM1 in different cancers is not completely clarified. In the present study, we examined CEACAM1 expression and its association with patient survival in various cancers by analysis of multiple databases. Oncomine database analysis re ...
DOI:
10.1007/s13205-020-2122-9
PubMed:
32154045
PubMed Central:
PMC7036084

5. ZEB and Snail expression indicates epithelial-mesenchymal transition in canine melanoma

Author:
Veloso, Emerson Soares; Gonçalves, Ivy Nayra Nascimento; Silveira, Tatiany Luiza; Espirito Santo, Juliane Taynar; Figueiredo, Larissa Vieira; Varaschin, Mary Suzan; Cassali, Geovanni Dantas; Del Puerto, Helen Lima; Ferreira, Enio
Source:
Research in veterinary science 2020 v.131 pp. 7-14
ISSN:
0034-5288
Subject:
cell adhesion,   etc   ; cadherins; cell membranes; cytoplasm; dogs; epithelium; melanoma; neoplasm cells; protein synthesis; transcription factors;     Show all 10 Subjects
Abstract:
... Melanoma progression is associated with the epithelial-mesenchymal transition (EMT) when tumor cells reduce E-cadherin and increase N-cadherin expression resulting in an escape from the microenvironment via loss of cellular adhesion and gain of motility. Transcription factor proteins Snail and ZEB trigger EMT by repression of epithelial markers and activation of mesenchymal properties. This study ...
DOI:
10.1016/j.rvsc.2020.04.007

6. Impact of molecular weight on polyelectrolyte multilayer assembly and surface properties

Author:
Towle, Elizabeth G.; Ding, Ivan; Peterson, Amy M.
Source:
Journal of colloid and interface science 2020 v.570 pp. 135-142
ISSN:
0021-9797
Subject:
cell adhesion,   etc   ; electrolytes; energy; finishes; molecular weight; polyacrylic acid; quartz crystal microbalance; roughness;     Show all 8 Subjects
Abstract:
... Polyelectrolyte multilayers (PEMs) are a versatile category of materials due to their ability to modify surface properties for applications ranging from protective coatings to improved cell adhesion. Polyelectrolyte choice, including its structure and molecular weight (MW), is known to greatly influence PEM assembly and surface properties. In this work, poly(acrylic acid)/poly-l-lysine PEMs using ...
DOI:
10.1016/j.jcis.2020.02.114

7. A comparative analysis of detachment forces and energies in initial and mature cell-material interaction

Author:
Wysotzki, Philipp; Sancho, Ana; Gimsa, Jan; Groll, Jürgen
Source:
Colloids and surfaces 2020 v.190 pp. 110894
ISSN:
0927-7765
Subject:
cell adhesion,   etc   ; adhesion; cell lines; collagen; energy; fibroblasts; fibronectins; glass; osteoblasts; spectroscopy;     Show all 10 Subjects
Abstract:
... Single cell force spectroscopy (SCFS) enables data on interaction forces to be acquired during the very early adhesion phase. However, SCFS detachment forces and energies have not been compared so far with the forces and energies after maturation of the cell-material contact on a single cell level and with comparable time resolution. We used FluidFM® to physically attach single cells to the cantil ...
DOI:
10.1016/j.colsurfb.2020.110894

8. The importance of force in microbial cell adhesion

Author:
El-Kirat-Chatel, Sofiane; Beaussart, Audrey; Mathelié-Guinlet, Marion; Dufrêne, Yves F.
Source:
Current opinion in colloid & interface science 2020 v.47 pp. 111-117
ISSN:
1359-0294
Subject:
cell adhesion,   etc   ; adhesion; antibodies; appendages; atomic force microscopy; biofilm; fimbriae; microorganisms; pathogens; peptides; proteins; sugars;     Show all 12 Subjects
Abstract:
... Microbes have evolved sophisticated strategies to colonize biotic and abiotic surfaces. Forces play a central role in microbial cell adhesion processes, yet until recently these were not accessible to study at the molecular scale. Unlike traditional assays, atomic force microscopy (AFM) is capable to study forces in single cell surface molecules and appendages, in their biologically relevant confo ...
DOI:
10.1016/j.cocis.2019.12.010

9. Universal surface modification using dopamine-hyaluronic acid conjugates for anti-biofouling

Author:
Lee, Sanghun; Kim, Semin; Park, Junggeon; Lee, Jae Young
Source:
International journal of biological macromolecules 2020 v.151 pp. 1314-1321
ISSN:
0141-8130
Subject:
cell adhesion,   etc   ; adsorption; biocompatible materials; biofouling; coatings; gold; hydrophilicity; pH; polymethylmethacrylate; polytetrafluoroethylene; polyurethanes; proteins;     Show all 12 Subjects
Abstract:
... Various materials are used to make implantable devices such as pumps, catheters, and stimulators. However, such implants inevitably undergo biofouling, which is associated with non-specific proteins and cell adhesion on the material surfaces. Severe biofouling often leads to adverse tissue reactions, such as foreign body responses, and thick scar tissue formation around the implantation, which in ...
DOI:
10.1016/j.ijbiomac.2019.10.177

10. Peculiarities of extracellular polymeric substances produced by Antarctic bacteria and their possible applications

Author:
Lo Giudice, Angelina; Poli, Annarita; Finore, Ilaria; Rizzo, Carmen
Source:
Applied microbiology and biotechnology 2020 v.104 no.7 pp. 2923-2934
ISSN:
0175-7598
Subject:
cell adhesion,   etc   ; marine environment; polymers; sea ice; seawater; soil; thermophilic bacteria; Antarctic region;     Show all 8 Subjects
Abstract:
... Extracellular polymeric substances (EPSs) possess diversified ecological role, including the cell adhesion to surfaces and cell protection, and are highly involved in the interactions between the bacterial cells and the bulk environments. Interestingly, EPSs find valuable applications in the industrial field, due to their chemical versatility. In this context, Antarctic bacteria have not been give ...
DOI:
10.1007/s00253-020-10448-8

11. Pectate lyases: Their role in plants and importance in fruit ripening

Author:
Uluisik, Selman; Seymour, Graham B.
Source:
Food chemistry 2020 v.309 pp. 125559
ISSN:
0308-8146
Subject:
cell adhesion,   etc   ; cell walls; cellulose; hemicellulose; pathogens; pectate lyase; pectins; plant development; porosity; proteins; ripening;     Show all 11 Subjects
Abstract:
... Plant cell walls are complex structures that are modified throughout development. They are a major contributor to the properties of plant structure and act as barriers against pathogens. The primary cell walls of plants are composed of polysaccharides and proteins. The polysaccharide fraction is divided into components cellulose, hemicelluloses and pectin, are all modified during fruit ripening. P ...
DOI:
10.1016/j.foodchem.2019.125559

12. An electrospun polyurethane scaffold-reinforced zwitterionic hydrogel as a biocompatible device

Author:
Liu, Sihang; Ma, Jun; Xu, Liangbo; Lin, Weifeng; Xue, Weili; Huang, Mei; Chen, Shengfu
Source:
Journal of materials chemistry B 2020 v.8 no.12 pp. 2443-2453
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; adsorption; biocompatibility; blood; fibrinogen; hydrogels; mechanical stress; polyurethanes; sulfobetaine; tensile strength; zwitterions;     Show all 11 Subjects
Abstract:
... Although zwitterionic hydrogels exhibit excellent hemocompatibility, their extremely low tensile strength is an obstacle for their use in blood-contacting devices. Electrospun fiber scaffold-reinforced zwitterionic hydrogels are a possible solution to overcome the challenges of both mechanical strength and hemocompatibility. In this work, electrospun polyurethane (ePU) fiber scaffold-reinforced su ...
DOI:
10.1039/c9tb02870f

13. Adherent self-healing chitosan/dialdehyde starch coating

Author:
Ren, Jiaoyu; Li, Minli; Yuan, Renqiang; Pang, Aiping; Lu, Zuhong; Ge, Liqin
Source:
Colloids and surfaces 2020 v.586 pp. 124203
ISSN:
0927-7757
Subject:
cell adhesion,   etc   ; Fourier transform infrared spectroscopy; adhesion; chitosan; coatings; mechanical stress; schiff bases; starch;     Show all 8 Subjects
Abstract:
... Self-healing functional coatings have gained worldwide attention as its potential application in many fields. A series of self-healing coatings, which are composed of chitosan (CH) and dialdehyde starch (DS) are built by via Schiff base linkage in this work. The properties of the Schiff base bonded coatings have been characterized, for example, the Fourier transform infrared (FTIR) spectra, swelli ...
DOI:
10.1016/j.colsurfa.2019.124203

14. Polypropylene mesh for hernia repair with controllable cell adhesion/de-adhesion properties

Author:
Lanzalaco, Sonia; Del Valle, Luis Javier; Turon, Pau; Weis, Christine; Estrany, Francesc; Alemán, Carlos; Armelin, Elaine
Source:
Journal of materials chemistry B 2020 v.8 no.5 pp. 1049-1059
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; chemical bonding; cold; epithelium; fibroblasts; hernia; hydrogels; polypropylenes; porous media; temperature; thermosensitivity;     Show all 11 Subjects
Abstract:
... Herein, a versatile bilayer system, composed by a polypropylene (PP) mesh and a covalently bonded poly(N-isopropylacrylamide) (PNIPAAm) hydrogel, is reported. The cell adhesion mechanism was successfully modulated by controlling the architecture of the hydrogel in terms of duration of PNIPAAm grafting time, crosslinker content, and temperature of material exposure in PBS solutions (below and above ...
DOI:
10.1039/c9tb02537e

15. Thermoresponsive polymers and their biomedical application in tissue engineering – a review

Author:
Doberenz, Falko; Zeng, Kui; Willems, Christian; Zhang, Kai; Groth, Thomas
Source:
Journal of materials chemistry B 2020 v.8 no.4 pp. 607-628
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; adsorption; drugs; physical properties; polymers; polypeptides; three-dimensional printing; tissue engineering;     Show all 8 Subjects
Abstract:
... Thermoresponsive polymers hold great potential in the biomedical field, since they enable the fabrication of cell sheets, in situ drug delivery and 3D-printing under physiological conditions. In this review we provide an overview of several thermoresponsive polymers and their application, with focus on poly(N-isopropylacrylamide)-surfaces for cell sheet engineering. Basic knowledge of important pr ...
DOI:
10.1039/c9tb02052g

16. Stretching of fibroblast cells on micropatterned gelatin on silicone elastomer

Author:
Müller, Stefan; Ueda, Motoki; Isoshima, Takashi; Ushida, Takashi; Ito, Yoshihiro
Source:
Journal of materials chemistry B 2020 v.8 no.3 pp. 416-425
ISSN:
2050-7518
Subject:
cell adhesion,   etc   ; benzoic acids; cytoskeleton; deformation; fibroblasts; gelatin; hydrolysis; microscopy; moieties; oxygen; silicone; wettability;     Show all 12 Subjects
Abstract:
... Here, the surface of silicone elastomer was modified with photo-reactive gelatin bearing azidophenyl groups. Two types of gelatin were prepared: one by coupling with azidoaniline and the other by coupling with azidobenzoic acid. The silicone surface was hydrolyzed by oxygen plasma and then gelatin was micropatterned on the surface using a photomask. The surface wettability was tuned by these treat ...
DOI:
10.1039/c9tb02203a

17. Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites

Author:
Debons, Nicolas; Dems, Dounia; Hélary, Christophe; Le Grill, Sylvain; Picaut, Lise; Renaud, Flore; Delsuc, Nicolas; Schanne-Klein, Marie-Claire; Coradin, Thibaud; Aimé, Carole
Source:
Biomaterials science 2020 v.8 no.2 pp. 569-576
ISSN:
2047-4849
Subject:
cell adhesion,   etc   ; cell differentiation; cell-matrix junctions; collagen; epitopes; laminin; nanocomposites; signal transduction; silica;     Show all 9 Subjects
Abstract:
... Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a laminin epitope (IKVAV) crucial for cell–matrix adhesion and signal transduction. This combines scaffolding and signaling and shows that local tuning of collagen organization enhances cell differentiation. ...
DOI:
10.1039/c9bm01029g

18. Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN

Author:
Gao, Haifei; Gonçalves, Cristine; Gallego, Téo; François-Heude, Marc; Malard, Virginie; Mateo, Véronique; Lemoine, François; Cendret, Virginie; Djedaini-Pilard, Florence; Moreau, Vincent; Pichon, Chantal; Midoux, Patrick
Source:
Carbohydrate research 2020 v.487 pp. 107877
ISSN:
0008-6215
Subject:
cell adhesion,   etc   ; antigens; humans; lipids; liposomes (artificial); mannose; monocytes; oligosaccharides; receptors;     Show all 9 Subjects
Abstract:
... Mannose Receptor (MR) and DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) are two mannose-specific targets for antigens carried by liposomes but DC-SIGN is more specific of DCs. Here, DC targeting is addressed by using DPPC/DOPE liposomes decorated with a series of diether lipids with a polar head of either a mannose (Man), tri-antenna of α-d-mannopyranoside (Tri-Man) ...
DOI:
10.1016/j.carres.2019.107877

19. Netrin Synergizes Signaling and Adhesion through DCC

Author:
Meijers, Rob; Smock, Robert G.; Zhang, Yan; Wang, Jia-Huai
Source:
Trends in biochemical sciences 2020 v.45 no.1 pp. 6-12
ISSN:
0968-0004
Subject:
cell adhesion,   etc   ; adhesion; axons; cell movement; colorectal neoplasms; environmental factors; receptors; tissues;     Show all 8 Subjects
Abstract:
... Netrin is a prototypical axon guidance cue. Structural studies have revealed how netrin interacts with the deleted in colorectal cancer (DCC) receptor, other receptors, and co-factors for signaling. Recently, genetic studies suggested that netrin is involved in neuronal haptotaxis, which requires a reversible adhesion process. Structural data indicate that netrin can also mediate trans-adhesion be ...
DOI:
10.1016/j.tibs.2019.10.005

20. Zein hydrolysate and its peptides exert anti-inflammatory activity on endothelial cells by preventing TNF-α-induced NF-κB activation

Author:
Liang, Qiufang; Chalamaiah, Meram; Liao, Wang; Ren, Xiaofeng; Ma, Haile; Wu, Jianping
Source:
Journal of functional foods 2020 v.64 pp. 103598
ISSN:
1756-4646
Subject:
cell adhesion; vascular cell adhesion molecules,   etc   ; adhesion; anti-inflammatory activity; cardiovascular diseases; endothelial cells; hydrolysates; inflammation; intercellular adhesion molecule-1; monocytes; necrosis; neoplasms; oxidative stress; phosphorylation; transcription factor NF-kappa B; tumor necrosis factor receptors; tumor necrosis factor-alpha; zein;     Show all 18 Subjects
Abstract:
... Vascular inflammation and oxidative stress are the major causes of endothelial dysfunction leading to cardiovascular disease. Previously, we have reported the anti-inflammatory activity of zein hydrolysate and its-derived peptides. However, the underlying mechanisms have not been understood. In this study, we report that zein hydrolysate and its derived peptides can inhibit the tumor necrosis fact ...
DOI:
10.1016/j.jff.2019.103598