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cellgrowth, etc ; acoustics; cell cycle; disease diagnosis; drugs; extrusion; hydrodynamics; medicine; microfluidic technology; Show all 9 Subjects
Abstract:
... Cell deformability plays an important role in cellular processes and functions, including cell growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at the single-cell level has attracted great interest in biomedicine owing to its importance in various applications, such as cell separation, disease diagnosis, and drug screening. Therefore, an accurate, robust ...
cellgrowth, etc ; endocytosis; gene expression; homeostasis; lanthanum; leaves; plant growth; plasma membrane; soybeans; toxicity; Show all 10 Subjects
Abstract:
... Light rare earth elements (LREEs) have been long used in agriculture (i.e., mainly via aerially applied LREE fertilizers) based on the fact that low-dose LREEs promote plant growth. Meanwhile, the toxic effects of low-dose LREEs on organisms have also been found. However, the cellular and molecular mechanism of low-dose LREEs acting on organisms remain unclear. Plants are at the beginning of food ...
... Compared with typical two-dimensional electrodes, the three-dimensional (3D) cell culture platform can simulate the real cell survival environment for cell growth to accurately reproduce cell functions. Moreover, considering that living cells are exposed to various of mechanical force in the microenvironment, the construction of 3D electrodes with excellent flexible, stretchable, and biocompatibil ...
cellgrowth, etc ; Artemia franciscana; Siphoviridae; Vibrio parahaemolyticus; adsorption; bacteriophages; biological control; food pathogens; food safety; gastroenteritis; genomics; microbial load; multiple drug resistance; pH; seafoods; seawater; Show all 16 Subjects
Abstract:
... Vibrio parahaemolyticus is a major seafood-borne zoonotic pathogen causing gastroenteritis in humans. Although antibiotics are the most effective chemical agents for V. parahaemolyticus, their abuse has caused the emergence of multidrug-resistant strains, affecting seafood safety. Here, we have isolated and characterized the V. parahaemolyticus bacteriophage VPG01 as an eco-friendly sustainable al ...
cellgrowth, etc ; 2-methylisoborneol; Ceratophyllum demersum; Hydrilla verticillata; Myriophyllum spicatum; Potamogeton crispus; Pseudanabaena; Vallisneria; algae; freshwater; lakes; macrophytes; metabolism; nutrient uptake; odors; off flavors; pioneer species; risk; water quality; Show all 19 Subjects
Abstract:
... The off-flavor compound 2-methylisoborneol (2-MIB) is generally associated with the proliferation and metabolism of filamentous cyanobacteria in shallow freshwater ecosystems. Here field monitoring in East Taihu Lake from July to October 2021, along with cultural experiments, was conducted to determine the impact of submerged macrophytes on the growth and 2-MIB production of filamentous cyanobacte ...
... Cadmium (Cd) induces severe soil pollution worldwide and exerts adverse effects on paddy field arthropods. Spiders grant a novel perspective to assess the Cd-induced toxicity, yet the impacts of long-term Cd stress on spider silk glands and its underlying mechanism remain elusive. The study showed that Cd stress enervated the antioxidant system in the spider Pardosa pseudoannulata, manifested as t ...
... Hepatocellular carcinoma (HCC) or hepatoma is malignant cancer that starts from the main liver cells. Although various classical methods have been used for patients with HCC, various molecular mechanisms involved in HCC progression should be invested. Previous studies demonstrated that abnormal expression of long non-coding RNAs (lncRNAs) presented important roles in the pathogenesis of HCC cells. ...
cellgrowth, etc ; humans; hydrostatic pressure; liver cirrhosis; Show all 4 Subjects
Abstract:
... Elevated interstitial fluid hydrostatic pressure is commonly observed in diseased livers. We herein examined the hypothesis that hydrostatic pressure induces hepatic stellate cells to acquire profibrotic properties under pathological conditions. Human hepatic stellate cells were exposed to 50 mmHg pressure for 24 h. Although we observed few changes of cell growth and morphology, PCR array data on ...
cellgrowth, etc ; biotechnology; communications technology; fermentation; gene deletion; Show all 5 Subjects
Abstract:
... With advantages of low substrates cost, high optical purity of end products and environmentally friendly fermentation process, microbial production of valuable chemicals grow rapidly. Compared with static microbial strain engineering strategies, such as gene deletion, overexpression and mutation, dynamic pathway regulation is a new approach that balances cellular growth and chemical production. Qu ...
cellgrowth, etc ; barium titanate; bones; electrodes; energy; porosity; Show all 6 Subjects
Abstract:
... Dedicated hierarchical structuring of functional ceramics can be used to shift the limits of functionality. This work presents the manufacturing of highly open porous, hierarchically structured barium titanate ceramics with 3-3 connectivity via direct ink writing of capillary suspension-type inks. The pore size of the printed struts (∼1 μm) is combined with a printed mesostructure (∼100 μm). The s ...
cellgrowth, etc ; metabolism; mice; morphogenesis; phosphotransferases (kinases); rapamycin; Show all 6 Subjects
Abstract:
... The skin epidermis, with its capacity for lifelong self-renewal and rapid repairing response upon injury, must maintain an active status in metabolism. Mechanistic target of rapamycin (mTOR) signaling is a central controller of cellular growth and metabolism that coordinates diverse physiological and pathological processes in a variety of tissues and organs. Recent evidence with genetic mouse mode ...
cellgrowth, etc ; Arabidopsis thaliana; hypocotyls; microgravity; microtubules; tubulin; Show all 6 Subjects
Abstract:
... How microgravity in space influences plant cell growth is an important issue for plant cell biology as well as space biology. We investigated the role of cortical microtubules in the stimulation of elongation growth in Arabidopsis (Arabidopsis thaliana) hypocotyls under microgravity conditions with the Resist Tubule space experiment. The epidermal cells in the lower half of the hypocotyls of wild- ...
cellgrowth, etc ; body weight; metabolism; ontogeny; surface area; Show all 5 Subjects
Abstract:
... Metabolic rate and its covariation with body mass vary substantially within and among species in little understood ways. Here, I critically review explanations (and supporting data) concerning how cell size and number and their establishment by cell expansion and multiplication may affect metabolic rate and its scaling with body mass. Cell size and growth may affect size-specific metabolic rate, a ...
cellgrowth, etc ; non-coding RNA; thermodynamics; transcription factors; Show all 4 Subjects
Abstract:
... 7SK is a conserved noncoding RNA that regulates transcription by sequestering the transcription factor P-TEFb. 7SK function entails complex changes in RNA structure, but characterizing RNA dynamics in cells remains an unsolved challenge. We developed a single-molecule chemical probing strategy, DANCE-MaP (deconvolution and annotation of ribonucleic conformational ensembles), that defines per-nucle ...
cellgrowth, etc ; Escherichia coli; protein synthesis; ribosomes; stoichiometry; Show all 5 Subjects
Abstract:
... Understanding how cells grow and adapt under various nutrient conditions is pivotal in the study of biological stoichiometry. Recent studies provide empirical evidence that cells use multiple strategies to maintain an optimal protein production rate under different nutrient conditions. Mathematical models can provide a solid theoretical foundation that can explain experimental observations and gen ...
cellgrowth, etc ; colorectal neoplasms; models; neoplasm cells; xenotransplantation; Show all 5 Subjects
Abstract:
... Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among these, the clinicopathological significance and molecular mechanisms of Daxx overexpression in colorectal cancer (CRC) remain unknown. Here, we showed that Daxx expression was increased in both clinical CRC samples and CRC cell lines. Daxx knockdown significantly reduced proliferation act ...
cellgrowth, etc ; bone formation; compression strength; pH; polylactic acid; Show all 5 Subjects
Abstract:
... Porous bone scaffolds based on high-precision 3D printing technology gave recently been developed for use in bone defect repair. However, conventional scaffold materials have poor mechanical properties and low osteogenic activity, limiting their clinical use. In this study, a porous composite tissue-engineered bone scaffold was prepared using polylactic acid, nano-hydroxyapatite, and nano-magnesiu ...
cellgrowth, etc ; Ciliophora; autocrine signaling; loci; pheromones; Antarctic region; Show all 6 Subjects
Abstract:
... In ciliates, diffusible cell type-specific pheromones regulate cell growth and mating phenomena acting competitively in both autocrine and heterologous fashion. In Euplotes species, these signaling molecules are represented by species-specific families of structurally homologous small, disulfide-rich proteins, each specified by one of a series of multiple alleles that are inherited without relatio ...
cellgrowth, etc ; Drosophila; Echinoidea; Xenopus; homeostasis; lithium; stem cells; Show all 7 Subjects
Abstract:
... Wnt signalling plays an eminent role in development, stem cell growth, and tissue homeostasis. Much of what we know about Wnt signalling, we owe to research in developmental biology. Here I review some salient discoveries in the older literature, beginning with the Lithium experiments in sea urchin by Curt Herbst in the 1890ies, when unknown to him he observed the gradual effects of Wnt overactiva ...
cellgrowth, etc ; biosynthesis; endoplasmic reticulum; genome; lipids; nuclear membrane; Show all 6 Subjects
Abstract:
... The nuclear envelope (NE) is a protective barrier to the genome, yet its membranes undergo highly dynamic remodeling processes that are necessary for cell growth and maintenance. While mechanisms by which proteins promote NE remodeling are emerging, the types of bilayer lipids and the lipid‐protein interactions that define and sculpt nuclear membranes remain elusive. The NE is continuous with the ...