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chemicalcompounds, etc ; European Union; Salvia officinalis; essential oils; food additives; food industry; ingredients; oils; postharvest technology; raw materials; sage; temperature; weed control; Show all 13 Subjects
Abstract:
... Salvia officinalis is commonly used as an ingredient in the food industry and has been shown to possess several biological activities. The essential oil (EO) of S. officinalis is characterized by thujones compounds, which are subjected to certain limits in the European Union (EU), as food additive. Sage inflorescences have different profile compared to leaves, with lower content in thujones, and c ...
chemicalcompounds, etc ; T-lymphocytes; antibodies; drugs; surface plasmon resonance; Show all 5 Subjects
Abstract:
... The use of intracellular antibodies as templates to derive surrogate compounds is an important objective because intracellular antibodies can be employed initially for target validation in pre-clinical assays and subsequently employed in compound library screens. LMO2 is a T cell oncogenic protein activated in the majority of T cell acute leukaemias. We have used an inhibitory intracellular antibo ...
chemicalcompounds, etc ; Ganoderma lucidum; active ingredients; agriculture; antifungal properties; corn; corn stover; crop yield; functional foods; gene expression; germination; greenhouses; induced resistance; medicine; pesticide use reduction; polysaccharides; root rot; seedlings; wheat; China; Show all 20 Subjects
Abstract:
... Ganoderma lucidum polysaccharide (GLP), which is the primary active ingredient in G. lucidum, has been widely used in functional food and clinical medicine. However, it is rarely reported in the prevention and control of plant diseases. In this study, we found that the GLP can increase the germination rates and seedling heights of maize and wheat. We also found that the combination of GLP and chem ...
chemicalcompounds, etc ; adhesion; attitudes and opinions; biotechnology; microparticles; tissue engineering; tissues; Show all 7 Subjects
Abstract:
... The modulation of cells in tissue formation is still one of the hardest tasks to achieve in Tissue Engineering. To control the cell response when undergoing their normal functions such as adhesion, differentiation, assembly, or maturation is vital the development of more successful solutions. Herein, we discuss how microparticles are being overlooked in their potential for controlling the cellular ...
Lilia Alejandra Conde-Hernández; Anette Gisela Botello-Ojeda; Alejandro Augusto Alonso-Calderón; María Auxilio Osorio-Lama; María Beatríz Bernabé-Loranca; Edith Chavez-Bravo
chemicalcompounds, etc ; antioxidant activity; essential oils; response surface methodology; systematic review; Show all 5 Subjects
Abstract:
... Extraction methods to obtain essential oils are usually influenced by many parameters. The optimization of the process is crucial because the extraction yield is low, i.e., less than 5 %. Fortunately, there are different ways to obtain essential oils and therefore to optimize the process. This article reviews recent studies regarding the use of Response Surface Methodology (RSM) in the optimizatio ...
chemicalcompounds, etc ; Ferula; algorithms; flora; fruit morphology; fruits; microstructure; morphometry; phylogeny; Central Asia; Show all 10 Subjects
Abstract:
... A comprehensive study was conducted on the fruits of 49 Ferula species, mostly from Central Asia, to describe the fruit surface microstructure and understand the systematic significance of this character for infrageneric delimitation. Ancestral states of the key morphometric characters were reconstructed via Mesquite, and distribution of informative characters at generic level was inferred using a ...
chemicalcompounds, etc ; brain; cell lines; drug therapy; genes; metastasis; neoplasms; protein synthesis; research; Show all 9 Subjects
Abstract:
... Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim of the present study was to identify small compounds that have activity to inhibit BEX2 expression and result in the attenuation of CSC-related pheno ...
chemicalcompounds, etc ; Gentiana; habitats; mountains; plant biochemistry; population; sampling; secondary metabolites; separation; underground parts; variability; Show all 11 Subjects
Abstract:
... Natural populations of Gentiana asclepiadea L., located at two mountainous sites, were HPLC-analyzed regarding the contents of six representative secondary metabolites. The contents of swertiamarin (SWM), gentiopicrin (GP), sweroside (SWZ), mangiferin (MGF), isoorientin (ISOOR), and isovitexin (ISOV) were determined in six populations (three per study site), and separately for aboveground and belo ...
... A propeller-like pyrene derivative of diphenyl-1-pyrenylphosphine (DPPP) is designed and synthesized. DPPP exhibits a unique photo-triggered AIE/ACQ transition with a remarkable third-order nonlinear optical signal change, which is proved to originate from the photo-induced oxidation of a phosphorus atom. ...
... Compact “push–pull” photochromic diaryethenes (DAEs) with unsymmetric oxidation pattern of the benzothiophene core display multicolour fluorescence switching, as a result of dual emission from both “open” and “closed” forms. These DAEs also present an unprecedented photo-fatigue resistance. ...
Rajnish Kumar; Farhat Ullah Khan; Anju Sharma; Mohammed Haris Siddiqui; Izzatdin BA Aziz; Mohammad Amjad Kamal; Ghulam Md Ashraf; Badrah S. Alghamdi; Md. Sahab Uddin
chemicalcompounds, etc ; cosmetics; cost effectiveness; models; mutagenicity; mutagens; pollution; prediction; research; risk; support vector machines; wastewater; Show all 12 Subjects
Abstract:
... We are exposed to various chemical compounds present in the environment, cosmetics, and drugs almost every day. Mutagenicity is a valuable property that plays a significant role in establishing a chemical compound’s safety. Exposure and handling of mutagenic chemicals in the environment pose a high health risk; therefore, identification and screening of these chemicals are essential. Considering t ...
chemicalcompounds, etc ; Salmo trutta; acute exposure; aquaculture; eggs; fish; fish development; overdose; selenium; survival rate; toxicity; Show all 11 Subjects
Abstract:
... Adequate selenium (Se) availability enhances the health and growth of organisms, but overdose of it can be harmful and pathogenic. The study’s objective was to analyse the impact of short-term exposure of sea trout fertilised eggs to inorganic selenium (SeO₂) at concentrations from 0 to 32 mg Se L⁻¹ to find the optimal and toxic dose of Se on early fish development. Se accumulated in the body, emb ...
chemicalcompounds, etc ; chemical reactions; enantioselectivity; Show all 3 Subjects
Abstract:
... An efficient enantioselective dearomatization of 2-nitrobenzofurans was realized via an organocatalyzed one-step Michael addition process. This method provides a facile strategy to access a range of structurally diverse 3,3′-disubstituted oxindoles, which feature an intriguing combination of two privileged motifs including 3-pyrrolyl-substituted-oxindoles and 2,3-dihydrobenzofurans substructures, ...
... The operation of DNA nanodevices is often limited by erroneous strand displacement. Here we demonstrate simple design principles that reduce such leakage by up to two orders of magnitude. Enhanced operational robustness against multiple spurious inputs was obtained by simply relocating toehold overhangs to external locations and strengthening adjacent G–C clamping. ...
chemicalcompounds, etc ; chemical reactions; fluorescence; Show all 3 Subjects
Abstract:
... Embedding a boroxazine (B₃N₂O) heterocycle by a m-quinquephenyl scaffold renders a B/N/O substituted nanographene molecule. The target compound can be synthesized in four steps and in good overall yield. The incorporation of a boroxazine core modifies the electronic structure and results in high fluorescence quantum yield. ...
... Homogeneous DNA-only keypad locks were built with multi-stranded scalable junction substrates and a series of double-stranded eliminators to differentially process correctly- and wrongly-added DNA inputs, respectively. Unlike conventional strategies that employed solid-phase platforms, one-pot assay of multiple DNA inputs was achieved, showing merits in fabricating complicated information security ...
... The peroxotungstate oxidation-mediated two-phase amplification system (POM-TPAS) is applied for the first time to the sensitive detection of locus-specific 5-hydroxymethylcytosine (5hmC) in DNA with low non-specific amplification. This strategy greatly shortens reaction time, improves sensitivity, and reduces non-specific amplification. ...
... The proton conduction of {NBu₂(CH₂COOH)₂}[MnCr(ox)₃] (dic-MnCr) is studied in comparison with its analogous {NBu₃(CH₂COOH)}[MnCr(ox)₃] (moc-MnCr). The proton conductivity is enhanced remarkably by the multiplication of the carboxyl carrier in the cation, from 5.2 × 10⁻⁷ S cm⁻¹ at 90% RH (25 °C) in moc-MnCr to 1.8 × 10⁻³ S cm⁻¹ at 95% RH (25 °C) in dic-MnCr. ...
chemicalcompounds, etc ; Bovine leukemia virus; antiviral agents; antiviral properties; fungi; livestock and meat industry; transactivators; transcriptional activation; virology; Show all 9 Subjects
Abstract:
... Bovine leukemia virus (BLV) infection has spread worldwide causing significant economic losses in the livestock industry. In countries with a high prevalence of BLV, minimizing economic losses is challenging; thus, research into various countermeasures is important for improving BLV control. Because anti-BLV drugs have not been developed, the present study explored a promising chemical compound wi ...
chemicalcompounds, etc ; carbon; nitrogen; quantum mechanics; Show all 4 Subjects
Abstract:
... Based on the results of a quantum chemical calculation using the DFT B3PW91/TZVP, MP2/TZVP and MP3/TZVP levels, the possibility of the existence of carbon–nitrogen compounds having the unusual carbon : nitrogen ratio 1 : 12, which is unknown for these elements at present, was shown. Data on the structural parameters are presented; it was shown that all CN₄ groupings are strictly planar. In additio ...